AutismKB 2.0

Annotation Detail for PPARGC1A


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Basic Information Top
Gene Symbol:PPARGC1A ( LEM6,PGC-1(alpha),PGC-1v,PGC1,PGC1A,PPARGC1 )
Gene Full Name: peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
Band: 4p15.2
Quick LinksEntrez ID:10891; OMIM: 604517; Uniprot ID:PRGC1_HUMAN; ENSEMBL ID: ENSG00000109819; HGNC ID: 9237
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa04920Adipocytokine signaling pathway
hsa04910Insulin signaling pathway
hsa05016Huntington's disease
No data
Pathway IDPathway Name
200154Signaling mediated by p38-alpha and p38-beta
200020Signaling events mediated by HDAC Class III
200080mTOR signaling pathway
200116ATF-2 transcription factor network
No data
No data
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1859Ovarian cancer
1879Glucose intolerance
1944Breast cancer
2091Hypertension
2102Polycystic ovary syndrome
2120Rabies
2197Metabolism disease
2237Neoplasm metastasis
Desease Name
aerobic fitness insulin
NORMALVARIATION
CARDIOVASCULAR
Birth Weight
CANCER
altered lipid oxidation and early insulin secretion
lipids
bone density
endurance performance
breast cancer
hypertension
Ventricular Dysfunction, Left
METABOLIC
obesity
insulin
REPRODUCTION
diabetes, type 2
cardiomyopathy hypertension left ventricular hypertrophy
intima media thickness
Diabetes Mellitus, Type 2
No data
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C095284 1H-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one 1H-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one inhibits the reaction [Carbon Monoxide results in increased expression of PPARGC1A protein]decreases reaction|increases expression 17179207
C085911 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Carbon Monoxide promotes the reaction [NRF1 protein binds to PPARGC1A protein]]affects binding|decreases reaction|increases reaction 17179207
C085911 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Carbon Monoxide results in increased expression of PPARGC1A protein]decreases reaction|increases expression 17179207
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene results in decreased expression of PPARGC1A mRNAdecreases expression 20406850
C457499 2-chloro-5-nitrobenzanilide 2-chloro-5-nitrobenzanilide inhibits the reaction [alitretinoin results in increased expression of PPARGC1A mRNA]decreases reaction|increases expression 16513826
C457499 2-chloro-5-nitrobenzanilide 2-chloro-5-nitrobenzanilide inhibits the reaction [rosiglitazone results in increased expression of PPARGC1A mRNA]decreases reaction|increases expression 16513826
C108123 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [tert-Butylhydroperoxide results in increased expression of PPARGC1A protein]decreases reaction|increases expression 17116659
C016601 4-hydroxytamoxifen 4-hydroxytamoxifen inhibits the reaction [PPARGC1A protein binds to ESRRG protein]affects binding|decreases reaction 16889744
D000082 Acetaminophen Acetaminophen affects the expression of PPARGC1A mRNAaffects expression 17562736
D000242 Cyclic AMP Cyclic AMP promotes the reaction [PPARGC1A protein binds to CYP2A5 promoter]affects binding|increases reaction 18602936
D000242 Cyclic AMP Cyclic AMP results in increased expression of PPARGC1A mRNAincreases expression 18602936
D016604 Aflatoxin B1 Aflatoxin B1 affects the expression of PPARGC1A proteinaffects expression 20106945
C430898 AGN 194204 AGN 194204 results in increased expression of PPARGC1A mRNAincreases expression 16513826
D000420 Albuterol Albuterol results in increased expression of PPARGC1A mRNAincreases expression 17446185
D000450 Aldosterone Aldosterone results in increased expression of PPARGC1A mRNAincreases expression 19808358
D000450 Aldosterone [Aldosterone binds to NR3C2 protein] which binds to PPARGC1A protein alternative formaffects binding 15761029
C103303 alitretinoin alitretinoin results in increased expression of PPARGC1A mRNAincreases expression 16513826
C103303 alitretinoin 2-chloro-5-nitrobenzanilide inhibits the reaction [alitretinoin results in increased expression of PPARGC1A mRNA]decreases reaction|increases expression 16513826
C103303 alitretinoin alitretinoin results in increased expression of PPARGC1A mRNAincreases expression 16513826
C103303 alitretinoin PPARG protein promotes the reaction [alitretinoin results in increased expression of PPARGC1A mRNA]increases expression|increases reaction 16513826
C103303 alitretinoin RXRA protein promotes the reaction [alitretinoin results in increased expression of PPARGC1A mRNA]increases expression|increases reaction 16513826
D000643 Ammonium Chloride Ammonium Chloride affects the expression of PPARGC1A mRNAaffects expression 16483693
C006632 arsenic trioxide arsenic trioxide results in increased expression of PPARGC1A mRNAincreases expression 20458559
D017638 Asbestos, Crocidolite Asbestos, Crocidolite affects the expression of PPARGC1A mRNAaffects expression 17331233
D001564 Benzo(a)pyrene Benzo(a)pyrene results in decreased expression of PPARGC1A mRNAdecreases expression 20106945
D001629 Bezafibrate Bezafibrate results in increased expression of PPARGC1A mRNAincreases expression 17275789
D020122 tert-Butylhydroperoxide PPARGC1A protein results in decreased susceptibility to tert-Butylhydroperoxidedecreases response to substance 17460188
D020122 tert-Butylhydroperoxide 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [tert-Butylhydroperoxide results in increased expression of PPARGC1A protein]decreases reaction|increases expression 17116659
D020122 tert-Butylhydroperoxide SB 203580 inhibits the reaction [tert-Butylhydroperoxide results in increased expression of PPARGC1A protein]decreases reaction|increases expression 17116659
D020122 tert-Butylhydroperoxide tert-Butylhydroperoxide results in increased expression of PPARGC1A proteinincreases expression 17116659
D020122 tert-Butylhydroperoxide tyrphostin AG 1478 inhibits the reaction [tert-Butylhydroperoxide results in increased expression of PPARGC1A protein]decreases reaction|increases expression 17116659
D002248 Carbon Monoxide Carbon Monoxide results in increased expression of PPARGC1A mRNAincreases expression 17179207
D002248 Carbon Monoxide 1H-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one inhibits the reaction [Carbon Monoxide results in increased expression of PPARGC1A protein]decreases reaction|increases expression 17179207
D002248 Carbon Monoxide 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Carbon Monoxide promotes the reaction [NRF1 protein binds to PPARGC1A protein]]affects binding|decreases reaction|increases reaction 17179207
D002248 Carbon Monoxide 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Carbon Monoxide results in increased expression of PPARGC1A protein]decreases reaction|increases expression 17179207
D002248 Carbon Monoxide Carbon Monoxide promotes the reaction [NRF1 protein binds to PPARGC1A protein]affects binding|increases reaction 17179207
D002248 Carbon Monoxide Carbon Monoxide results in increased expression of PPARGC1A proteinincreases expression 17179207
D002791 Cholesterol, Dietary Cholesterol, Dietary results in increased expression of PPARGC1A mRNAincreases expression 19509184
D002791 Cholesterol, Dietary [Fructose co-treated with Dietary Fats co-treated with Cholesterol, Dietary] results in increased expression of PPARGC1A mRNAaffects cotreatment|increases expression 19509184
C039671 ciglitazone ciglitazone results in increased expression of PPARGC1A mRNAincreases expression 16513826
C039671 ciglitazone PPARG protein promotes the reaction [ciglitazone results in increased expression of PPARGC1A mRNA]increases expression|increases reaction 16513826
D002976 Clenbuterol Clenbuterol results in increased expression of PPARGC1A mRNAincreases expression 17446185
D002976 Clenbuterol Propranolol inhibits the reaction [Clenbuterol results in increased expression of PPARGC1A mRNA]decreases reaction|increases expression 17446185
D002976 Clenbuterol Clenbuterol results in increased expression of PPARGC1A mRNAincreases expression 17446185
D016572 Cyclosporine Cyclosporine results in decreased expression of PPARGC1A mRNAdecreases expression 20106945
D003907 Dexamethasone Dexamethasone results in increased expression of PPARGC1A mRNAincreases expression 19022236
D003907 Dexamethasone Dexamethasone results in increased expression of PPARGC1A mRNAincreases expression 18972406
D003907 Dexamethasone INS protein inhibits the reaction [Dexamethasone results in increased expression of PPARGC1A mRNA]decreases reaction|increases expression 18972406
D004041 Dietary Fats [Fructose co-treated with Dietary Fats co-treated with Cholesterol, Dietary] results in increased expression of PPARGC1A mRNAaffects cotreatment|increases expression 19509184
D004041 Dietary Fats Dietary Fats results in decreased expression of PPARGC1A mRNAdecreases expression 18457598
D004041 Dietary Fats Dietary Fats results in increased expression of PPARGC1A mRNAincreases expression 18042831
D002117 Calcitriol Calcitriol promotes the reaction [VDR protein binds to PPARGC1A protein]affects binding|increases reaction 15908514
D004958 Estradiol [Progesterone co-treated with Estradiol] results in increased expression of PPARGC1A mRNAaffects cotreatment|increases expression 17404688
D000431 Ethanol Ethanol results in increased expression of PPARGC1A mRNAincreases expression 16098508
D005576 Forskolin Forskolin results in increased expression of PPARGC1A mRNAincreases expression 16357189
D005632 Fructose Fructose results in decreased expression of PPARGC1A mRNAdecreases expression 18063403
D005632 Fructose [Fructose co-treated with Dietary Fats co-treated with Cholesterol, Dietary] results in increased expression of PPARGC1A mRNAaffects cotreatment|increases expression 19509184
D005632 Fructose Fructose results in increased expression of PPARGC1A mRNAincreases expression 19196556
D005632 Fructose Fructose results in increased expression of PPARGC1A proteinincreases expression 19196556
D005632 Fructose rosiglitazone inhibits the reaction [Fructose results in increased expression of PPARGC1A protein]decreases reaction|increases expression 19196556
D005947 Glucose Glucose deficiency results in decreased expression of PPARGC1A mRNAdecreases expression 17855661
D005947 Glucose Nitroprusside inhibits the reaction [Glucose deficiency results in decreased expression of PPARGC1A mRNA]decreases expression|decreases reaction 17855661
C425931 GW 501516 [GW 501516 co-treated with PPARD protein] results in increased expression of PPARGC1A mRNAaffects cotreatment|increases expression 17275789
C425931 GW 501516 GW 501516 results in increased expression of PPARGC1A mRNAincreases expression 17275789
C056599 icariin icariin results in increased expression of PPARGC1A mRNAincreases expression 17883938
C056599 icariin icariin results in increased expression of PPARGC1A proteinincreases expression 17883938
C026777 ICI 118551 ICI 118551 results in decreased expression of PPARGC1A mRNAdecreases expression 17446185
D007545 Isoproterenol Isoproterenol results in increased expression of PPARGC1A mRNAincreases expression 19808358
C006552 kaempferol kaempferol results in increased expression of PPARGC1A mRNAincreases expression 17327447
C082161 lipopolysaccharide A lipopolysaccharide A results in decreased expression of PPARGC1A mRNAdecreases expression 16061943
D008070 Lipopolysaccharides Lipopolysaccharides results in decreased expression of PPARGC1A mRNAdecreases expression 16847310
C063509 N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Norepinephrine results in increased expression of PPARGC1A mRNA]decreases reaction|increases expression 16513826
D009599 Nitroprusside Nitroprusside inhibits the reaction [Glucose deficiency results in decreased expression of PPARGC1A mRNA]decreases expression|decreases reaction 17855661
D009638 Norepinephrine N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Norepinephrine results in increased expression of PPARGC1A mRNA]decreases reaction|increases expression 16513826
D009638 Norepinephrine Norepinephrine results in increased expression of PPARGC1A mRNAincreases expression 16513826
D009638 Norepinephrine [Propranolol co-treated with Prazosin] inhibits the reaction [Norepinephrine results in increased expression of PPARGC1A mRNA]affects cotreatment|decreases reaction|increases expression 16513826
D009638 Norepinephrine Norepinephrine inhibits the reaction [Testosterone results in decreased expression of PPARGC1A mRNA]decreases expression|decreases reaction 16954335
C041786 palm oil palm oil results in increased expression of PPARGC1A mRNAincreases expression 18042831
D010634 Phenobarbital Phenobarbital results in increased expression of PPARGC1A mRNAincreases expression 19270015
D010833 Phytic Acid [resveratrol co-treated with Quercetin co-treated with Phytic Acid] results in increased expression of PPARGC1A mRNAaffects cotreatment|increases expression 18657603
C006253 pirinixic acid [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of PPARGC1A mRNAaffects binding|decreases expression|increases activity 19710929
C006253 pirinixic acid pirinixic acid promotes the reaction [PPARGC1B protein results in decreased expression of PPARGC1A mRNA]decreases expression|increases reaction 17932310
C006253 pirinixic acid pirinixic acid results in increased expression of PPARGC1A mRNAincreases expression 18445702
17275789
D011224 Prazosin [Propranolol co-treated with Prazosin] inhibits the reaction [Norepinephrine results in increased expression of PPARGC1A mRNA]affects cotreatment|decreases reaction|increases expression 16513826
D011374 Progesterone [Progesterone co-treated with Estradiol] results in increased expression of PPARGC1A mRNAaffects cotreatment|increases expression 17404688
D011374 Progesterone Progesterone results in increased expression of PPARGC1A mRNAincreases expression 17404688
D011433 Propranolol [Propranolol co-treated with Prazosin] inhibits the reaction [Norepinephrine results in increased expression of PPARGC1A mRNA]affects cotreatment|decreases reaction|increases expression 16513826
D011433 Propranolol Propranolol inhibits the reaction [Clenbuterol results in increased expression of PPARGC1A mRNA]decreases reaction|increases expression 17446185
D011433 Propranolol Propranolol results in decreased expression of PPARGC1A mRNAdecreases expression 17446185
C031280 pyrazole pyrazole results in decreased expression of PPARGC1A mRNAdecreases expression 17945193
D011794 Quercetin Quercetin results in increased expression of PPARGC1A mRNAincreases expression 19211721
D011794 Quercetin [resveratrol co-treated with Quercetin co-treated with Phytic Acid] results in increased expression of PPARGC1A mRNAaffects cotreatment|increases expression 18657603
C059514 resveratrol resveratrol results in increased expression of PPARGC1A proteinincreases expression 16849586
C059514 resveratrol [resveratrol co-treated with Quercetin co-treated with Phytic Acid] results in increased expression of PPARGC1A mRNAaffects cotreatment|increases expression 18657603
C059514 resveratrol resveratrol promotes the reaction [SIRT1 protein results in decreased acetylation of PPARGC1A protein]decreases acetylation|increases reaction 17581637
C059514 resveratrol resveratrol results in decreased acetylation of and results in increased activity of PPARGC1A proteindecreases acetylation|increases activity 17112576
C059514 resveratrol resveratrol results in decreased acetylation of PPARGC1A proteindecreases acetylation 17581637
C059514 resveratrol resveratrol results in increased activity of PPARGC1A proteinincreases activity 17086191
C059514 resveratrol resveratrol results in increased expression of PPARGC1A mRNAincreases expression 17438283
D012293 Rifampin Rifampin promotes the reaction [PPARGC1A protein binds to CYP2A6 promoter]affects binding|increases reaction 16857725
C089730 rosiglitazone rosiglitazone results in increased expression of PPARGC1A mRNAincreases expression 16513826
C089730 rosiglitazone 2-chloro-5-nitrobenzanilide inhibits the reaction [rosiglitazone results in increased expression of PPARGC1A mRNA]decreases reaction|increases expression 16513826
C089730 rosiglitazone PPARGC1A protein promotes the reaction [rosiglitazone results in increased expression of PPARGC1A mRNA]increases expression|increases reaction 16513826
C089730 rosiglitazone PPARGC1A protein promotes the reaction [rosiglitazone results in increased expression of UCP1 mRNA]increases expression|increases reaction 16513826
C089730 rosiglitazone [PPARG protein co-treated with RXRA protein] promotes the reaction [rosiglitazone results in increased expression of PPARGC1A mRNA]affects cotreatment|increases expression|increases reaction 16513826
C089730 rosiglitazone PPARG protein promotes the reaction [rosiglitazone results in increased expression of PPARGC1A mRNA]increases expression|increases reaction 16513826
C089730 rosiglitazone rosiglitazone results in increased expression of PPARGC1A mRNAincreases expression 16513826
C089730 rosiglitazone rosiglitazone results in increased expression of PPARGC1A proteinincreases expression 16513826
C089730 rosiglitazone rosiglitazone inhibits the reaction [Fructose results in increased expression of PPARGC1A protein]decreases reaction|increases expression 19196556
C057823 salmeterol salmeterol results in increased expression of PPARGC1A mRNAincreases expression 17446185
C093642 SB 203580 SB 203580 inhibits the reaction [tert-Butylhydroperoxide results in increased expression of PPARGC1A protein]decreases reaction|increases expression 17116659
C017947 sodium arsenite sodium arsenite results in increased expression of PPARGC1A mRNAincreases expression 19822182
D013629 Tamoxifen Tamoxifen inhibits the reaction [PPARGC1A protein binds to ESRRG protein]affects binding|decreases reaction 16889744
D013739 Testosterone Norepinephrine inhibits the reaction [Testosterone results in decreased expression of PPARGC1A mRNA]decreases expression|decreases reaction 16954335
D013739 Testosterone Testosterone results in decreased expression of PPARGC1A mRNAdecreases expression 16954335
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of PPARGC1A mRNAdecreases expression 20106945
D014212 Tretinoin Tretinoin results in increased expression of PPARGC1A mRNAincreases expression 16840543
C057693 troglitazone PPARG protein promotes the reaction [troglitazone results in increased expression of PPARGC1A mRNA]increases expression|increases reaction 16513826
C057693 troglitazone troglitazone results in increased expression of PPARGC1A mRNAincreases expression 16513826
D014425 Turpentine Turpentine results in decreased expression of PPARGC1A mRNAdecreases expression 16061943
C101044 tyrphostin AG 1478 tyrphostin AG 1478 inhibits the reaction [tert-Butylhydroperoxide results in increased expression of PPARGC1A protein]decreases reaction|increases expression 17116659
D014801 Vitamin A Vitamin A affects the reaction [PPARGC1A protein binds to PCK1 promoter]affects binding|affects reaction 16317119
C488234 XCT790 XCT790 results in decreased expression of PPARGC1A proteindecreases expression 19464277
D015054 Zymosan Zymosan results in decreased expression of PPARGC1A mRNAdecreases expression 16061943
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 3.8614745880
MESH:D000014 Abnormalities, Drug-Induced Ethanol 10.4118926900 17676605
MESH:D000014 Abnormalities, Drug-Induced Phenobarbital 10.416195326
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 10.4111752688 14514962 15322242
MESH:D000015 Abnormalities, Multiple Vitamin A 4.2610992263
MESH:D000138 Acidosis Ammonium Chloride 8.2518287403
MESH:D000138 Acidosis Ethanol 8.2511192467
MESH:D058186 Acute Kidney Injury resveratrol 3.2616538975
MESH:D055371 Acute Lung Injury Lipopolysaccharides 6.9811850527 18653653
MESH:D055371 Acute Lung Injury pirinixic acid 6.9818653653
MESH:D000210 Acute-Phase Reaction Turpentine 5.5016044259
MESH:D000230 Adenocarcinoma arsenic trioxide 5.7311798837 19825857
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 5.7320127859 20464547
MESH:D000230 Adenocarcinoma Estradiol 5.7311473722
MESH:D000236 Adenoma Benzo(a)pyrene 5.386695378
MESH:D000236 Adenoma resveratrol 5.3815688382
MESH:D018248 Adenoma, Liver Cell Phenobarbital 13.4217620307
MESH:D018248 Adenoma, Liver Cell pirinixic acid 13.4216434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 13.4216835633
MESH:D000310 Adrenal Gland Neoplasms sodium arsenite 4.0115276417
MESH:D018246 Adrenocortical Adenoma sodium arsenite 4.2217306315 16712894
MESH:D020268 Alcohol-Induced Disorders, Nervous System Ethanol 4.6315451040 15451039
MESH:D000505 Alopecia Tretinoin 3.0715955085
MESH:D000544 Alzheimer Disease Cholesterol, Dietary 7.8720157255
MESH:D000544 Alzheimer Disease icariin 7.8719858766 19782061
MESH:D000544 Alzheimer Disease resveratrol 7.8716162502 16183991
MESH:D000544 Alzheimer Disease rosiglitazone 7.8719621015
MESH:D000740 Anemia Tetrachlorodibenzodioxin 11.6311748828
MESH:D000740 Anemia Vitamin A 11.6316960172
MESH:D000740 Anemia Zymosan 11.6318664788
MESH:D000743 Anemia, Hemolytic Quercetin 3.6317084956
MESH:D018798 Anemia, Iron-Deficiency Vitamin A 4.2116960172
MESH:D000799 Angioedema Acetaminophen 9.9910982225
MESH:D000799 Angioedema salmeterol 9.9910982225
MESH:D000853 Anophthalmos Ethanol 4.1615513904
MESH:D000987 Antisocial Personality Disorder Testosterone 5.177506515
MESH:D001008 Anxiety Disorders Ethanol 3.4611141031
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 3.4219183758
MESH:D001161 Arteriosclerosis Cholesterol, Dietary 8.5215552841
MESH:D001161 Arteriosclerosis Dietary Fats 8.5215238619
MESH:D001169 Arthritis, Experimental Dexamethasone 13.9217659584
MESH:D001169 Arthritis, Experimental resveratrol 13.9217115116
MESH:D001169 Arthritis, Experimental Tretinoin 13.9216412693
MESH:D001169 Arthritis, Experimental Zymosan 13.9215944321 15188379 17659584 15142272 16872482
MESH:D001172 Arthritis, Rheumatoid Tretinoin 2.0716292516
MESH:D001249 Asthma Albuterol 9.309949315 11991558
MESH:D001249 Asthma salmeterol 9.3010359889 11694805
MESH:D001249 Asthma Tretinoin 9.3016456186
MESH:D001249 Asthma Vitamin A 9.3016732791
MESH:D001250 Asthma, Exercise-Induced salmeterol 5.4410984370
MESH:D001260 Ataxia Telangiectasia Quercetin 4.3015336622
MESH:D050197 Atherosclerosis resveratrol 2.8516873680 17967414
MESH:D001321 Autistic Disorder Acetaminophen 2.3418445737
MESH:D001321 Autistic Disorder Norepinephrine 2.348570775
MESH:D001321 Autistic Disorder Propranolol 2.3418766980
MESH:D001327 Autoimmune Diseases Quercetin 3.7519761891
MESH:D001471 Barrett Esophagus Tretinoin 3.7616935849
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 17.0016206674
MESH:D001778 Blood Coagulation Disorders pirinixic acid 17.0019483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 17.0012125929
MESH:D001778 Blood Coagulation Disorders Tretinoin 17.0016206674 16197459
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.1115340226
MESH:D001847 Bone Diseases icariin 5.7318295595
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.3015746008
MESH:D001919 Bradycardia Isoproterenol 9.116740701
MESH:D001919 Bradycardia Propranolol 9.116740701
MESH:D020201 Brain Hemorrhage, Traumatic Progesterone 4.6517868700
MESH:D001930 Brain Injuries Nitroprusside 9.2414637104
MESH:D001930 Brain Injuries Progesterone 9.2415665606 15380490 15845082
MESH:D002545 Brain Ischemia icariin 8.5219303870
MESH:D002545 Brain Ischemia resveratrol 8.5217600658
MESH:D001943 Breast Neoplasms alitretinoin 9.5516344269
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 9.5517474063 20146248
MESH:D001943 Breast Neoplasms Calcitriol 9.5511237771
MESH:D001943 Breast Neoplasms Dietary Fats 9.5520435547
MESH:D001943 Breast Neoplasms Estradiol 9.5512948864 17289903 16675129 19861407 17261762 18497071 14630087 17018787
MESH:D001943 Breast Neoplasms kaempferol 9.5516756079
MESH:D001943 Breast Neoplasms Progesterone 9.5517614352 15562024 16175315
MESH:D001943 Breast Neoplasms Quercetin 9.5518628248
MESH:D001943 Breast Neoplasms resveratrol 9.5517534123 16393696 17651959
MESH:D001943 Breast Neoplasms Tamoxifen 9.5519410462 19155303 16273361 16818667 20390343 17893378 20859285 18821012 19288272 11161223 21152245 18351453 15668708 19011961 19487384 19059307 20005174 18815881 18425577 19244106 21138602 17242785 19084267 18629630 19289846 20065188 17440819 20135344 17049068 18855134 17261762 19221464 19103187 19189210 19200415 19142967 18984771 15565566 16873071 19066611 19115204 19189212 20544844 16202921 18997820
MESH:D001943 Breast Neoplasms Testosterone 9.5517261762
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 9.5520435547
MESH:D001943 Breast Neoplasms Tretinoin 9.5516873071 16443354 16166294
MESH:D016535 Bronchial Hyperreactivity tyrphostin AG 1478 4.3512794006
MESH:D029481 Bronchitis, Chronic salmeterol 5.8617687719
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 10.7916813970
MESH:D001997 Bronchopulmonary Dysplasia Vitamin A 10.7917426644 17377406
MESH:D002051 Burkitt Lymphoma arsenic trioxide 3.7011589617
MESH:D002056 Burns Ethanol 4.0016374292
MESH:D002105 Cadmium Poisoning Quercetin 4.8616962696
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 3.7916111702
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.2616835633
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 3.8519066611
MESH:D018236 Carcinoma, Embryonal Tretinoin 4.4716168501
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 25.1916705839
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 25.193084413
MESH:D006528 Carcinoma, Hepatocellular Aflatoxin B1 25.1921507988 12619106 12907637
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 25.1914691202 15553829 16217749 15073043 11135700
MESH:D006528 Carcinoma, Hepatocellular Estradiol 25.1916924424
MESH:D006528 Carcinoma, Hepatocellular Ethanol 25.1918788625 15763234 15289165
MESH:D006528 Carcinoma, Hepatocellular Phenobarbital 25.1917173139 1701930 20007298 20935162 6705139
MESH:D006528 Carcinoma, Hepatocellular Quercetin 25.1919519916 12508355
MESH:D006528 Carcinoma, Hepatocellular resveratrol 25.1919321006 16227395
MESH:D006528 Carcinoma, Hepatocellular sodium arsenite 25.1915276417 16507464 17306315
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 25.1916924424
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 25.191917145
MESH:D018827 Carcinoma, Lewis Lung resveratrol 3.9216675471
MESH:D021441 Carcinoma, Pancreatic Ductal Quercetin 4.3017234771
MESH:D002291 Carcinoma, Papillary arsenic trioxide 4.1919014326
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 3.5212490120
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 11.6020419170
MESH:D002294 Carcinoma, Squamous Cell Calcitriol 11.6011237771
MESH:D002294 Carcinoma, Squamous Cell resveratrol 11.6016227395
MESH:D002294 Carcinoma, Squamous Cell sodium arsenite 11.6018572023
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 11.6016096774 16051514
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 3.0317572228
MESH:D006332 Cardiomegaly Ethanol 17.1019332462
MESH:D006332 Cardiomegaly Isoproterenol 17.1011179087 7544033
MESH:D006332 Cardiomegaly Norepinephrine 17.1011179087
MESH:D006332 Cardiomegaly Quercetin 17.1019794523
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 17.1018670907 18850075 16120746
MESH:D002318 Cardiovascular Diseases Aldosterone 9.7311230374
MESH:D002318 Cardiovascular Diseases kaempferol 9.7316756079
MESH:D002318 Cardiovascular Diseases resveratrol 9.7315458977
MESH:D002375 Catalepsy Norepinephrine 4.878216760
MESH:D002386 Cataract Acetaminophen 5.7810977129
MESH:D002386 Cataract Tretinoin 5.7817460283
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 12.016135515
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 12.0112371664
MESH:D002471 Cell Transformation, Neoplastic Estradiol 12.0118566989
MESH:D002471 Cell Transformation, Neoplastic sodium arsenite 12.0119524636 20056578
MESH:D002493 Central Nervous System Diseases Phenobarbital 3.604080065
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 3.9216129372
MESH:D002659 Child Development Disorders, Pervasive Testosterone 3.3920678186
MESH:D015362 Child Nutrition Disorders Vitamin A 4.7916153327
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 2.5916835633
MESH:D002779 Cholestasis Cyclosporine 10.5419486331
MESH:D002779 Cholestasis pirinixic acid 10.5419176532
MESH:D002779 Cholestasis Vitamin A 10.5416175620
MESH:D002822 Choriocarcinoma Tretinoin 4.4716461808
MESH:D002971 Cleft Lip Ethanol 3.1915513904
MESH:D002972 Cleft Palate Ethanol 11.3715513904
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 11.3715668235 8697196 15340226 12621046 16354765
MESH:D002972 Cleft Palate Tretinoin 11.379407595
MESH:D002972 Cleft Palate Vitamin A 11.3716054864
MESH:D003092 Colitis Carbon Monoxide 12.5216365149
MESH:D003092 Colitis resveratrol 12.5216474422
MESH:D003092 Colitis Tretinoin 12.5217035595
MESH:D003110 Colonic Neoplasms Dexamethasone 6.8915824018
MESH:D003110 Colonic Neoplasms Quercetin 6.8915741050 17191121 11134977 19056647 17148506 16640504 19440933
MESH:D003110 Colonic Neoplasms resveratrol 6.8916338953
MESH:D003110 Colonic Neoplasms Vitamin A 6.8917219422 16267017
MESH:D015179 Colorectal Neoplasms arsenic trioxide 3.0220501625
MESH:D015179 Colorectal Neoplasms Quercetin 3.0218095365 18852136
MESH:D015179 Colorectal Neoplasms resveratrol 3.0216550006
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 2.4914669216 17141729
MESH:D003327 Coronary Disease Fructose 7.2318504504
MESH:D003327 Coronary Disease resveratrol 7.2316507316
MESH:D023903 Coronary Restenosis arsenic trioxide 3.5512609071
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 8.0010525206
MESH:D019465 Craniofacial Abnormalities Dexamethasone 8.0017728286
MESH:D019465 Craniofacial Abnormalities Ethanol 8.0015451040 11198716 15513904 19302082 10194807 11873399 15451039
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 8.0015322242 10048152 20055451
MESH:D019465 Craniofacial Abnormalities Tretinoin 8.0010589399 16925845 17551590 9224671 8800419 9664655 9125849 9211117 9142499 14991402
MESH:D019465 Craniofacial Abnormalities Vitamin A 8.0010992263
MESH:D003490 Cyanosis 2,6-dinitrotoluene 3.3618551238
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 3.4715213294
MESH:D003711 Demyelinating Diseases Tamoxifen 3.7119031437
MESH:D017449 Dermatitis, Allergic Contact Dexamethasone 2.8012438553
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.0718249437
MESH:D003920 Diabetes Mellitus rosiglitazone 3.7317446233
MESH:D003921 Diabetes Mellitus, Experimental Fructose 10.8918603373
MESH:D003921 Diabetes Mellitus, Experimental Quercetin 10.8919496084
MESH:D003921 Diabetes Mellitus, Experimental resveratrol 10.8916873680
MESH:D003922 Diabetes Mellitus, Type 1 Vitamin A 3.2616506275
MESH:D003924 Diabetes Mellitus, Type 2 Fructose 8.5118603373
MESH:D003924 Diabetes Mellitus, Type 2 rosiglitazone 8.5112642470
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 8.5117107852
MESH:D003924 Diabetes Mellitus, Type 2 troglitazone 8.5116023994
MESH:D003925 Diabetic Angiopathies troglitazone 4.9812601628
MESH:D003928 Diabetic Nephropathies Estradiol 11.7119279558
MESH:D003928 Diabetic Nephropathies resveratrol 11.7116286809
MESH:D003928 Diabetic Nephropathies Tamoxifen 11.7119279558
MESH:D003929 Diabetic Neuropathies Progesterone 3.8417187935
MESH:D003967 Diarrhea Dexamethasone 3.087237001
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 14.6821346803 18551238
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 14.6816081117 10663392 19164858 19416960 19085960 11739529 15968718 17562736 2444490 12153990 17522070 10774834 16177239 18713872 19923254 11529661 17906064 14725611 15619225 19370779 18071297 11743745 12705907 16393943 12958197 16781746 14986274 14550746 10915739 12540782 16109766 19739265 16227642 16485898 11287661 12392966 19420014 11461765 11421492 11834606 12594235
MESH:D056486 Drug-Induced Liver Injury Ethanol 14.6811566570
MESH:D056486 Drug-Induced Liver Injury Prazosin 14.6818071297
MESH:D056486 Drug-Induced Liver Injury pyrazole 14.6812499123
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 14.6820420201
MESH:D056486 Drug-Induced Liver Injury troglitazone 14.6814986274
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 3.4119426721
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.2511462148
MESH:D015352 Dry Eye Syndromes Vitamin A 5.1316146918
MESH:D050171 Dyslipidemias Dietary Fats 2.9518367378
MESH:D004417 Dyspnea Albuterol 5.1420016425
MESH:D004421 Dystonia Phenobarbital 3.381851702
MESH:C538011 Eales disease Vitamin A 4.939068938
MESH:D004480 Ectromelia Vitamin A 5.1416054864
MESH:D004485 Eczema Dexamethasone 3.8212438553
MESH:D004487 Edema Dexamethasone 19.3319703484
MESH:D004487 Edema pirinixic acid 19.3312083418
MESH:D004487 Edema resveratrol 19.338985016
MESH:D004487 Edema rosiglitazone 19.3312083418
MESH:D004487 Edema Tetrachlorodibenzodioxin 19.3312711302 11000095
MESH:D004487 Edema Zymosan 19.337907874
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 9.6718230668 15322242 16714409
MESH:D004489 Edema, Cardiac Tretinoin 9.6718230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Calcitriol 22.0515138306
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental ciglitazone 22.0516844232
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Progesterone 22.0517692515
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental resveratrol 22.0517872969
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 22.0519031437
MESH:D016889 Endometrial Neoplasms 4-hydroxytamoxifen 13.9619148513
MESH:D016889 Endometrial Neoplasms Estradiol 13.9611473722 18566989 19148513
MESH:D016889 Endometrial Neoplasms Tamoxifen 13.9617893378 20544844 16202921 19155303
MESH:D016889 Endometrial Neoplasms Tretinoin 13.9616569247
MESH:D004715 Endometriosis Progesterone 6.9716134523
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 6.9710568697 9294722
MESH:D019446 Endotoxemia Lipopolysaccharides 3.7315821434 17637181 15328337
MESH:D020345 Enterocolitis, Necrotizing resveratrol 4.1917923197
MESH:D004831 Epilepsies, Myoclonic Phenobarbital 3.453659116
MESH:D004828 Epilepsies, Partial Phenobarbital 3.1911558140 3922381
MESH:D004827 Epilepsy Norepinephrine 5.86821787
MESH:D004827 Epilepsy Phenobarbital 5.8620417680
MESH:D004832 Epilepsy, Absence Phenobarbital 2.976401628
MESH:D017029 Epilepsy, Complex Partial Phenobarbital 3.607750514
MESH:D004830 Epilepsy, Tonic-Clonic Phenobarbital 3.353659116
MESH:D007172 Erectile Dysfunction icariin 4.7916281085 15329286
MESH:D004938 Esophageal Neoplasms arsenic trioxide 5.9512903497
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 5.9516530937
MESH:D004938 Esophageal Neoplasms Ethanol 5.9516704527
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 7.1011564622
MESH:D005124 Eye Abnormalities Tretinoin 7.109664655 16938888
MESH:D005234 Fatty Liver arsenic trioxide 32.7915073043
MESH:D005234 Fatty Liver Cyclosporine 32.7919224547
MESH:D005234 Fatty Liver Dietary Fats 32.7918296743 19004024 17967931 19551842
MESH:D005234 Fatty Liver Ethanol 32.7919236843 18620774 16409862
MESH:D005234 Fatty Liver Fructose 32.7918395287 19196556 18641190
MESH:D005234 Fatty Liver pirinixic acid 32.7919236843 20131406
MESH:D005234 Fatty Liver rosiglitazone 32.7919196556
MESH:D005234 Fatty Liver Tamoxifen 32.7914986274 19224547
MESH:D005235 Fatty Liver, Alcoholic Ethanol 4.9817920746
MESH:D052776 Female Urogenital Diseases Tamoxifen 2.7916709447
MESH:D005310 Fetal Alcohol Syndrome Ethanol 4.6310194807 16946407 15451040 15513904
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 2.8011858732
MESH:D005327 Fetal Resorption Vitamin A 4.6816054864
MESH:D005334 Fever Lipopolysaccharides 3.4311852909 9205823
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 3.8614745880
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 3.5119069698
MESH:D005355 Fibrosis Albuterol 31.5315467267
MESH:D005355 Fibrosis Cyclosporine 31.5312168785 12639820
MESH:D005355 Fibrosis Dietary Fats 31.5318296743
MESH:D005355 Fibrosis Fructose 31.5318504504
MESH:D005355 Fibrosis Quercetin 31.5319474275
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 31.5320067830
MESH:D005355 Fibrosis Tretinoin 31.5317994277
MESH:D005391 Firesetting Behavior Testosterone 5.177506515
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 3.6216904648
MESH:D005739 Gas Poisoning Albuterol 5.5220016425
MESH:D005756 Gastritis Acetaminophen 8.8616983495
MESH:D005756 Gastritis Ethanol 8.8615046732
MESH:D005833 Genital Neoplasms, Female sodium arsenite 4.0116452187
MESH:D005885 Gingival Hyperplasia Cyclosporine 3.558708960
MESH:D005909 Glioblastoma Quercetin 9.3219804834
MESH:D005909 Glioblastoma Testosterone 9.3217162496
MESH:D005909 Glioblastoma Tretinoin 9.3217312396
MESH:D005910 Glioma Quercetin 2.7517643826
MESH:D018149 Glucose Intolerance Fructose 4.7019165636
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 3.9110696789
MESH:D006258 Head and Neck Neoplasms Tretinoin 2.7116096774
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 4.4716084493
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 12.7220471113
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 12.7210048152 11294989
MESH:D006330 Heart Defects, Congenital Tretinoin 12.7214991402 9664655
MESH:D006330 Heart Defects, Congenital Vitamin A 12.7210992263 16080930
MESH:D006333 Heart Failure marker/mechanism 19808358
MESH:D006333 Heart Failure Isoproterenol 9.5318097624
MESH:D006333 Heart Failure pirinixic acid 9.5320558911
MESH:D006333 Heart Failure Propranolol 9.5320082655
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 3.7515720958
MESH:D006463 Hemolytic-Uremic Syndrome Lipopolysaccharides 3.7916366002
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 2.7311000095
MESH:D006505 Hepatitis Zymosan 4.0719110552
MESH:D006529 Hepatomegaly Phenobarbital 15.4116109766
MESH:D006529 Hepatomegaly pirinixic acid 15.4116221962 19176532 18467677 19772884
MESH:D006529 Hepatomegaly Propranolol 15.4116371745
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 15.4112621046 16120746 15340226
MESH:D006548 Hernia, Diaphragmatic Dexamethasone 5.347520565
MESH:D006548 Hernia, Diaphragmatic Vitamin A 5.3416863852 16490937 16877224 16292552 17436238 15707848
MESH:D006558 Herpes Genitalis Estradiol 4.3515709030
MESH:D006561 Herpes Simplex resveratrol 3.5216876885
MESH:D006628 Hirsutism Testosterone 4.9717019078
MESH:D015658 HIV Infections Vitamin A 3.4416960176
MESH:D006679 HIV Seropositivity Vitamin A 4.9317209195
MESH:D006689 Hodgkin Disease sodium arsenite 2.6012676792
MESH:D019584 Hot Flashes Estradiol 3.0717088409
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.3615340226 18606429 8697196 16959395 16354765
MESH:D006930 Hyperalgesia Acetaminophen 18.7916870215
MESH:D006930 Hyperalgesia Ethanol 18.7918783367
MESH:D006930 Hyperalgesia Prazosin 18.7912727271
MESH:D006930 Hyperalgesia rosiglitazone 18.7912083418
MESH:D006930 Hyperalgesia Tretinoin 18.7916870215
MESH:D017588 Hyperandrogenism Testosterone 4.6217019078
MESH:D006937 Hypercholesterolemia Cholesterol, Dietary 12.0510876104
MESH:D006937 Hypercholesterolemia Dietary Fats 12.0521332399
MESH:D006937 Hypercholesterolemia resveratrol 12.0517188708
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 3.9116778211
MESH:D006943 Hyperglycemia kaempferol 12.4018262572
MESH:D006943 Hyperglycemia pirinixic acid 12.4020558911
MESH:D006943 Hyperglycemia Quercetin 12.4011834736 18262572
MESH:D006946 Hyperinsulinism Fructose 4.3319008412 18360027 14757778 15752949 18563319
MESH:D006949 Hyperlipidemias Dietary Fats 12.0121332399
MESH:D006949 Hyperlipidemias Fructose 12.0115752949
MESH:D006949 Hyperlipidemias resveratrol 12.0116873680
MESH:D006973 Hypertension Cyclosporine 13.0810903974
MESH:D006973 Hypertension Dexamethasone 13.0817042910
MESH:D006973 Hypertension Fructose 13.0819008412 14633139 14568997 16843071 14573337
MESH:D006973 Hypertension Quercetin 13.0818356687
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 13.0818850075 18670907
MESH:D015228 Hypertriglyceridemia Fructose 4.4919342510 19799862
MESH:D006984 Hypertrophy Isoproterenol 4.5912791704
MESH:D017379 Hypertrophy, Left Ventricular resveratrol 3.7117488730
MESH:D006986 Hypervitaminosis A Vitamin A 5.4816054864
MESH:D007006 Hypogonadism Testosterone 4.0912002444
MESH:D007018 Hypopituitarism Testosterone 5.5217426086
MESH:D007022 Hypotension Isoproterenol 12.096740701
MESH:D007022 Hypotension Norepinephrine 12.096740701
MESH:D007022 Hypotension Propranolol 12.096740701
MESH:D007174 Impulse Control Disorders Testosterone 5.177506515
MESH:D020244 Infarction, Middle Cerebral Artery Progesterone 9.3115869954
MESH:D020244 Infarction, Middle Cerebral Artery resveratrol 9.3117600658
MESH:D007248 Infertility, Male sodium arsenite 2.5315346721 12646999
MESH:D007249 Inflammation Dexamethasone 25.328960868 11099482
MESH:D007249 Inflammation Dietary Fats 25.3220412841
MESH:D007249 Inflammation Lipopolysaccharides 25.3212878042 17237260 9205823 17255318 17963957
MESH:D007249 Inflammation Progesterone 25.3215869954
MESH:D007249 Inflammation resveratrol 25.3216366677
MESH:D007249 Inflammation rosiglitazone 25.3212083418
MESH:D007249 Inflammation Tamoxifen 25.3219457130
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 25.3212200463 12878042
MESH:D007249 Inflammation Zymosan 25.3211289658 8014878
MESH:D007251 Influenza, Human Quercetin 8.9316624496
MESH:D007251 Influenza, Human resveratrol 8.9316624496
MESH:D007333 Insulin Resistance Dietary Fats 18.2418457598 11836018
MESH:D007333 Insulin Resistance Estradiol 18.2416393666 16627594
MESH:D007333 Insulin Resistance Fructose 18.2418981581 19799862 19586609 17133782 18563319 18057795 19008412 14757778 14633139 19342510 14573337
MESH:D007333 Insulin Resistance pirinixic acid 18.2416306350
MESH:D007333 Insulin Resistance rosiglitazone 18.2416306350
MESH:D007410 Intestinal Diseases Tretinoin 3.1217994277
MESH:D019586 Intracranial Hypertension Vitamin A 5.1415955940
MESH:D019189 Iron Metabolism Disorders Lipopolysaccharides 4.0117255318
MESH:D043183 Irritable Bowel Syndrome Zymosan 5.1617553498
MESH:D007569 Jaw Abnormalities Ethanol 13.6815513904
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 13.6816580747
MESH:D007569 Jaw Abnormalities Tretinoin 13.6815992940 17551590
MESH:D007627 Keloid Quercetin 4.3017086741
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 3.7615604871
MESH:D017492 Keratosis, Seborrheic alitretinoin 4.9616144296
MESH:D007674 Kidney Diseases Acetaminophen 14.5215629191 12587719
MESH:D007674 Kidney Diseases Cyclosporine 14.528314463 10903974 18776723
MESH:D007674 Kidney Diseases Estradiol 14.5215618244
MESH:D007674 Kidney Diseases Quercetin 14.5216962696
MESH:D007674 Kidney Diseases sodium arsenite 14.5220008137
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 13.2016705839
MESH:D007680 Kidney Neoplasms Cyclosporine 13.2012371664
MESH:D007680 Kidney Neoplasms Estradiol 13.2015610895
MESH:D007680 Kidney Neoplasms Tamoxifen 13.2018625569
MESH:D007859 Learning Disorders Ethanol 8.0815451040
MESH:D007859 Learning Disorders icariin 8.0819782061
MESH:D007938 Leukemia 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one 15.6712970779
MESH:D007938 Leukemia arsenic trioxide 15.6715070760
MESH:D007938 Leukemia kaempferol 15.6717468513
MESH:D007938 Leukemia Quercetin 15.6717468513
MESH:D007938 Leukemia Tretinoin 15.6717143497
MESH:D004915 Leukemia, Erythroblastic, Acute troglitazone 5.4616085563
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 3.1912560223 17077332
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 3.6416972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 2.9114633726
MESH:D007951 Leukemia, Myeloid arsenic trioxide 7.4619077051
MESH:D007951 Leukemia, Myeloid Tretinoin 7.4616482212 16932348 19285840
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 3.3216467208 20471514 16968895 17050201 19850784
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 3.3216294345 19850784 17596541
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 10.0511161223 17107899 16966277 17712046 16330433 19642359 16891316 16112521 15748426 17649720 15213294 16823087 19075265 12018890 19225113 19035177 15622746 12712474 16331271 9834237 15336539 17217047 17869043 11468182 12679006
MESH:D015473 Leukemia, Promyelocytic, Acute resveratrol 10.0516087638
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 10.0516823087 17217047 17294898 19075265 16766008 17301526 17649720 16891316 17368321 16140955 19035177 17361223 19642359 17506722 16331271 16935935 15748426 19225113 17712046 12679006 16788101 19029980 17107899 17339181 9834237
MESH:D015458 Leukemia, T-Cell arsenic trioxide 3.7116882451
MESH:D007970 Leukopenia Lipopolysaccharides 4.0315821434
MESH:D017880 Limb Deformities, Congenital Ethanol 10.9117676605
MESH:D017880 Limb Deformities, Congenital Tretinoin 10.919224671
MESH:D017880 Limb Deformities, Congenital Vitamin A 10.9116054864
MESH:D008064 Lipidoses Tamoxifen 2.6615342952 17567588
MESH:D008103 Liver Cirrhosis Dietary Fats 12.4318296743
MESH:D008103 Liver Cirrhosis Ethanol 12.4315289165
MESH:D008103 Liver Cirrhosis Phenobarbital 12.4321047994
MESH:D008103 Liver Cirrhosis Vitamin A 12.4316256175
MESH:D008104 Liver Cirrhosis, Alcoholic Ethanol 4.4218295389
MESH:D008106 Liver Cirrhosis, Experimental Dexamethasone 17.8016718785
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 17.8014716833 14659978
MESH:D008106 Liver Cirrhosis, Experimental Ethanol 17.8018166357
MESH:D008106 Liver Cirrhosis, Experimental Lipopolysaccharides 17.8012878042
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 17.8015474484
MESH:D008106 Liver Cirrhosis, Experimental Quercetin 17.8012741479
MESH:D008106 Liver Cirrhosis, Experimental rosiglitazone 17.8015980055 17347453
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 17.8018564211
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 17.8012878042
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 17.8016248980 18397230
MESH:D008106 Liver Cirrhosis, Experimental Vitamin A 17.8016248980
MESH:D008107 Liver Diseases Acetaminophen 7.5912969438 11587558 16611625 19014921 19784758 19460945 16610002 12587719
MESH:D008107 Liver Diseases Carbon Monoxide 7.5917173083
MESH:D008107 Liver Diseases Phenobarbital 7.5919363144
MESH:D008107 Liver Diseases Vitamin A 7.5916175620
MESH:D008108 Liver Diseases, Alcoholic Ethanol 9.3717347304 17207112
MESH:D008108 Liver Diseases, Alcoholic Vitamin A 9.3716762690
MESH:D017114 Liver Failure, Acute Acetaminophen 2.6517185352 16871587
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 35.037678174
MESH:D008113 Liver Neoplasms Aflatoxin B1 35.039163691 2125692 15890375 18177683
MESH:D008113 Liver Neoplasms arsenic trioxide 35.0314682389
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 35.0321137059 20195826
MESH:D008113 Liver Neoplasms Phenobarbital 35.038742319 21047994 19073162 15975961 19482888 19812893
MESH:D008113 Liver Neoplasms pirinixic acid 35.0320007298 15890375 16377806
MESH:D008113 Liver Neoplasms Quercetin 35.0318980244
MESH:D008113 Liver Neoplasms resveratrol 35.0320405173 19073162 19321006 19812893
MESH:D008113 Liver Neoplasms sodium arsenite 35.0315276417 16712894
MESH:D008113 Liver Neoplasms Tamoxifen 35.0316684651
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 35.0316984957
MESH:D008113 Liver Neoplasms XCT790 35.0319464277
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 21.342876784 2876786 6135515
MESH:D008114 Liver Neoplasms, Experimental Aflatoxin B1 21.348603461
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 21.3420377131
MESH:D008114 Liver Neoplasms, Experimental Phenobarbital 21.3417172636 2563599 18308698 6150874 1399818
MESH:D008114 Liver Neoplasms, Experimental Quercetin 21.3419519916
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 21.3412151625
MESH:D008114 Liver Neoplasms, Experimental Vitamin A 21.3417113696
MESH:D008133 Long QT Syndrome arsenic trioxide 2.8315213294
MESH:D008171 Lung Diseases sodium arsenite 6.1819095001
MESH:D008171 Lung Diseases Vitamin A 6.1816863852
MESH:D055370 Lung Injury Asbestos, Crocidolite 7.1417365036
MESH:D055370 Lung Injury Lipopolysaccharides 7.1421114838
MESH:D008175 Lung Neoplasms Aflatoxin B1 15.1314755239
MESH:D008175 Lung Neoplasms alitretinoin 15.1316413115
MESH:D008175 Lung Neoplasms arsenic trioxide 15.1311798837 19825857
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 15.1320869020 18569708 6695378 17053015 18816296 18520028 20135361 20464547 20064080
MESH:D008175 Lung Neoplasms ciglitazone 15.1315899809
MESH:D008175 Lung Neoplasms Dexamethasone 15.1315824018 11195469
MESH:D008175 Lung Neoplasms Quercetin 15.1316280456
MESH:D008175 Lung Neoplasms sodium arsenite 15.1315276417 17306315 17077188 16712894 19931552
MESH:D008175 Lung Neoplasms Tamoxifen 15.1318625569
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 15.1319555203 11884234
MESH:D008178 Lupus Erythematosus, Cutaneous Rifampin 5.4611422169
MESH:D008180 Lupus Erythematosus, Systemic Rifampin 3.7411422169
MESH:D016393 Lymphoma, B-Cell resveratrol 3.6817088997
MESH:D008228 Lymphoma, Non-Hodgkin resveratrol 3.3214749477
MESH:D015674 Mammary Neoplasms, Animal resveratrol 7.7815688416
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 7.7819428831
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 13.9416891317 17203775 11807958 11408345
MESH:D008325 Mammary Neoplasms, Experimental Progesterone 13.9411408345 17203775
MESH:D008325 Mammary Neoplasms, Experimental resveratrol 13.9411606380 8985016
MESH:D008325 Mammary Neoplasms, Experimental rosiglitazone 13.9416827153
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 13.9411731420 16827153 19196722 19196723 14580682
MESH:D020149 Manganese Poisoning Estradiol 10.3719453300
MESH:D020149 Manganese Poisoning Tamoxifen 10.3719453300
MESH:D008527 Medulloblastoma Tretinoin 2.4717453147
MESH:D008545 Melanoma Glucose 7.9814993021
MESH:D008545 Melanoma resveratrol 7.9817992120
MESH:D008545 Melanoma sodium arsenite 7.9819082730 16487513
MESH:D008545 Melanoma Tamoxifen 7.9812393984 19393235
MESH:D008545 Melanoma Tretinoin 7.9816752155
MESH:D018328 Melanoma, Amelanotic Tamoxifen 3.5115990972
MESH:D008546 Melanoma, Experimental Acetaminophen 2.9119513568
MESH:D008569 Memory Disorders Ethanol 8.0615451040 18411066
MESH:D008569 Memory Disorders icariin 8.0619782061
MESH:D008591 Meningomyelocele Tretinoin 3.7716940565
MESH:D008654 Mesothelioma Asbestos, Crocidolite 2.8716166281 16966607 18303189
MESH:D008659 Metabolic Diseases resveratrol 3.7717112576
MESH:D024821 Metabolic Syndrome X Fructose 8.1717098227 18497449 19165636 17261469 16815490
MESH:D024821 Metabolic Syndrome X rosiglitazone 8.1717261469
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.1016801185
MESH:D020326 Migraine without Aura Cyclic AMP 4.5211304026
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 2.6616381670
MESH:D009101 Multiple Myeloma arsenic trioxide 13.2215949261 11468182 14977855 19549372 19417148
MESH:D009101 Multiple Myeloma Dexamethasone 13.2215867202 16118317 15744524
MESH:D009101 Multiple Myeloma resveratrol 13.2216490592 17049120 17935668 17164350 16267019 14749477
MESH:D009101 Multiple Myeloma Vitamin A 13.2216374440
MESH:D009102 Multiple Organ Failure Zymosan 4.5918160304 10479408 12879239 12130978 15241586 10890648 15259001 17724436 15834315 15213630
MESH:D009134 Muscular Atrophy, Spinal resveratrol 4.2017962980
MESH:D009135 Muscular Diseases Bezafibrate 14.2616239165
MESH:D009135 Muscular Diseases GW 501516 14.2616239165
MESH:D009135 Muscular Diseases pirinixic acid 14.2616239165
MESH:D009164 Mycobacterium Infections Rifampin 4.8718474467
MESH:D009182 Mycosis Fungoides arsenic trioxide 3.9918349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 9.8916105982 16882451
MESH:D009190 Myelodysplastic Syndromes Dexamethasone 9.899809623
MESH:D009190 Myelodysplastic Syndromes Tretinoin 9.8917596541
MESH:D009203 Myocardial Infarction Isoproterenol 10.8615740881 16697266 19172585 17052832 19595682 16538859 16584858
MESH:D009203 Myocardial Infarction pirinixic acid 10.8619151258
MESH:D009203 Myocardial Infarction Quercetin 10.8619595682
MESH:D009203 Myocardial Infarction resveratrol 10.8616525036 16456233 17188708 17015251 17125593 16317513
MESH:D017202 Myocardial Ischemia resveratrol 7.1917015251 17125593
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 7.1912213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 16.0016810080
MESH:D015428 Myocardial Reperfusion Injury Norepinephrine 16.0015642760
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 16.0016411023
MESH:D015428 Myocardial Reperfusion Injury Quercetin 16.0019207477
MESH:D009205 Myocarditis resveratrol 4.0917322642
MESH:D020191 Myoclonic Epilepsies, Progressive Phenobarbital 3.8017484760
MESH:D009336 Necrosis 2,6-dinitrotoluene 3.1918551238 7678174
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 3.3216624393
MESH:D009362 Neoplasm Metastasis Tamoxifen 2.2419393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.2519410462
MESH:D009369 Neoplasms alitretinoin 14.8516946489
MESH:D009369 Neoplasms Benzo(a)pyrene 14.8511141357
MESH:D009369 Neoplasms pirinixic acid 14.8517405874
MESH:D009369 Neoplasms Quercetin 14.8515185748
MESH:D009369 Neoplasms sodium arsenite 14.8511559025
MESH:D009369 Neoplasms Tretinoin 14.8516594593 16946489
MESH:D009374 Neoplasms, Experimental resveratrol 7.078985016
MESH:D009374 Neoplasms, Experimental sodium arsenite 7.0720056578
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 3.3219196722 19200415 19189210
MESH:D009389 Neovascularization, Pathologic Estradiol 3.0717289903
MESH:D009402 Nephrosis, Lipoid Cyclosporine 3.7617954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 2.7119348381 18481113
MESH:D009421 Nervous System Malformations Estradiol 12.6511399458 16427766
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 12.6514600291
MESH:D009421 Nervous System Malformations Tretinoin 12.659125849
MESH:D009436 Neural Tube Defects arsenic trioxide 13.5310525206
MESH:D009436 Neural Tube Defects sodium arsenite 13.5312854658
MESH:D009436 Neural Tube Defects Tretinoin 13.539142499
MESH:D009436 Neural Tube Defects Vitamin A 13.5317400914
MESH:D019636 Neurodegenerative Diseases Acetaminophen 6.5018514411
MESH:D019636 Neurodegenerative Diseases resveratrol 6.5017652729
MESH:D020078 Neurogenic Inflammation Quercetin 8.6317929310
MESH:D020078 Neurogenic Inflammation resveratrol 8.6317929310
MESH:D009765 Obesity Dietary Fats 6.2121332399 20132043 16723640 19632207 18457598 18674790 17217161 11836018 20518802
MESH:D009765 Obesity Fructose 6.2117707055 18585860
MESH:D009765 Obesity pirinixic acid 6.2120558911
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 2.8516049721
MESH:D010018 Osteomalacia Phenobarbital 3.6917016548
MESH:D010024 Osteoporosis icariin 6.6918236786 19747809
MESH:D010024 Osteoporosis kaempferol 6.6916756079
MESH:D015663 Osteoporosis, Postmenopausal Quercetin 8.1419495926
MESH:D015663 Osteoporosis, Postmenopausal resveratrol 8.1417513867
MESH:D010051 Ovarian Neoplasms 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one 18.7816211241
MESH:D010051 Ovarian Neoplasms arsenic trioxide 18.7816624393 12452020 19769630
MESH:D010051 Ovarian Neoplasms Estradiol 18.7819401270
MESH:D010051 Ovarian Neoplasms Progesterone 18.7816525653 17393432
MESH:D010051 Ovarian Neoplasms Quercetin 18.7819005980
MESH:D010051 Ovarian Neoplasms sodium arsenite 18.7815276417 17306315
MESH:D010051 Ovarian Neoplasms Tretinoin 18.7816936753
MESH:D010146 Pain Acetaminophen 4.7816870215
MESH:D010146 Pain Tretinoin 4.7816870215
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 13.1415580305
MESH:D010190 Pancreatic Neoplasms Ethanol 13.1412384795
MESH:D010190 Pancreatic Neoplasms Phenobarbital 13.1416965848
MESH:D010190 Pancreatic Neoplasms Quercetin 13.1416965848
MESH:D010190 Pancreatic Neoplasms Tretinoin 13.1415976015
MESH:D010235 Paraganglioma arsenic trioxide 3.5419927285
MESH:D010300 Parkinson Disease Cholesterol, Dietary 3.8919014385
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 3.5612520081
MESH:D010538 Peritonitis Zymosan 4.2314761945 18977430 15979727 17826846 18557954 19641140 19088179 18760300 17371808 11985352 15259001
MESH:D010995 Pleural Diseases Asbestos, Crocidolite 4.2410923243
MESH:D011014 Pneumonia Lipopolysaccharides 3.8912224865 11605937
MESH:D017499 Porokeratosis alitretinoin 5.3216144296
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 2.9218163543
MESH:D011230 Precancerous Conditions Cyclosporine 12.0112371664
MESH:D011230 Precancerous Conditions Phenobarbital 12.012563599
MESH:D011230 Precancerous Conditions Quercetin 12.0119056647
MESH:D054198 Precursor Cell Lymphoblastic Leukemia-Lymphoma Dexamethasone 3.1321297632
MESH:D011297 Prenatal Exposure Delayed Effects resveratrol 7.3816679765
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 7.3811896295 11118676 11399792 11222880
MESH:D011470 Prostatic Hyperplasia Calcitriol 4.1115572423
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 8.8520887781
MESH:D019048 Prostatic Intraepithelial Neoplasia Testosterone 8.8520887781
MESH:D011471 Prostatic Neoplasms AGN 194204 2.5916000583
MESH:D011471 Prostatic Neoplasms arsenic trioxide 2.5919131511
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 2.5917292933
MESH:D011471 Prostatic Neoplasms Calcitriol 2.5912479363 15754350 16289102 18247401 16644109
MESH:D011471 Prostatic Neoplasms Estradiol 2.5916740699
MESH:D011471 Prostatic Neoplasms Quercetin 2.5917292933 14715546
MESH:D011471 Prostatic Neoplasms resveratrol 2.5916731767 17675339 15767336 17804756 17718901 17636462
MESH:D011471 Prostatic Neoplasms sodium arsenite 2.5916039940
MESH:D011471 Prostatic Neoplasms Tamoxifen 2.5915067354
MESH:D011507 Proteinuria Tretinoin 2.9916636307
MESH:D019310 Pseudolymphoma Phenobarbital 3.8112752131
MESH:D011565 Psoriasis Cyclosporine 1.9516882103
MESH:D011625 Pterygium Tretinoin 4.1216723453
MESH:D011654 Pulmonary Edema Isoproterenol 4.5710903255
MESH:D011658 Pulmonary Fibrosis Asbestos, Crocidolite 5.2317365031 15814490 17975199 17322281
MESH:D011658 Pulmonary Fibrosis troglitazone 5.2318162602
MESH:D051436 Renal Insufficiency, Chronic resveratrol 4.9016325855
MESH:D015427 Reperfusion Injury pirinixic acid 5.3119058328
MESH:D015427 Reperfusion Injury resveratrol 5.3116317513 16314181 17058453 17520802 15827377
MESH:D012128 Respiratory Distress Syndrome, Adult Dexamethasone 3.4018379247 11700416
MESH:D012127 Respiratory Distress Syndrome, Newborn Vitamin A 5.1316877224
MESH:D012130 Respiratory Hypersensitivity Lipopolysaccharides 3.2610835634
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.2018990726
MESH:D012208 Rhabdomyosarcoma Tretinoin 3.4816283617 16116481
MESH:D012468 Salivary Gland Neoplasms Progesterone 2.5718045962
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 3.3216646077
MESH:D012554 Schistosomiasis japonica Quercetin 4.8616862918
MESH:D012640 Seizures 2,6-dinitrotoluene 7.1218551238
MESH:D012640 Seizures Ethanol 7.129754883
MESH:D012640 Seizures Phenobarbital 7.123137016 11442880 4039156 16876388
MESH:D003294 Seizures, Febrile Phenobarbital 4.156407741
MESH:D018805 Sepsis Zymosan 4.0911441115
MESH:D012735 Sexual Dysfunction, Physiological Testosterone 5.5216631401
MESH:D012871 Skin Diseases Vitamin A 3.1518709164
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 21.5910029692 19755658
MESH:D012878 Skin Neoplasms Glucose 21.5914993021
MESH:D012878 Skin Neoplasms resveratrol 21.5915837718 8985016
MESH:D012878 Skin Neoplasms sodium arsenite 21.5919524636 18572023
MESH:D012878 Skin Neoplasms tert-Butylhydroperoxide 21.598532709
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 21.5916192470
MESH:D012878 Skin Neoplasms Tretinoin 21.5916467112
MESH:D013088 Spermatocele Tamoxifen 3.6116709447
MESH:D013119 Spinal Cord Injuries Progesterone 8.6516503802 15862959
MESH:D013119 Spinal Cord Injuries Tamoxifen 8.6519457130
MESH:D016135 Spinal Dysraphism sodium arsenite 3.2612854658
MESH:D013272 Stomach Diseases Dexamethasone 3.6615472012
MESH:D013274 Stomach Neoplasms arsenic trioxide 5.3417007042
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 5.342093021 20155912
MESH:D013274 Stomach Neoplasms Ethanol 5.3418456281
MESH:D013274 Stomach Neoplasms Tretinoin 5.3417261132
MESH:D013274 Stomach Neoplasms troglitazone 5.3415930296
MESH:D013276 Stomach Ulcer Dexamethasone 5.5915138204
MESH:D013276 Stomach Ulcer Ethanol 5.599562338 11906479 9211565 17918041 17189318 16755016
OMIM:601367 STROKE, ISCHEMIC resveratrol 3.8916321402
MESH:D013375 Substance Withdrawal Syndrome Ethanol 3.679754883
MESH:D013610 Tachycardia Nitroprusside 9.4815306635
MESH:D013610 Tachycardia Norepinephrine 9.483261545
MESH:D013733 Testicular Diseases pyrazole 4.156499806
MESH:D013921 Thrombocytopenia Lipopolysaccharides 3.5815821434
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.2212697716
MESH:D013964 Thyroid Neoplasms 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine 12.8816940797
MESH:D013964 Thyroid Neoplasms arsenic trioxide 12.8819014326
MESH:D013964 Thyroid Neoplasms Phenobarbital 12.881399818
MESH:D013964 Thyroid Neoplasms Tretinoin 12.8816026305 17045167
MESH:D013978 Tibial Fractures Estradiol 4.0019048282
MESH:D014062 Tongue Neoplasms resveratrol 7.9516227395
MESH:D014062 Tongue Neoplasms Tretinoin 7.9516051514
MESH:D016171 Torsades de Pointes arsenic trioxide 3.2915213294
MESH:D014376 Tuberculosis Rifampin 6.9218397238 15236969
MESH:D014376 Tuberculosis Tretinoin 6.9216040207
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 15.7216049721
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 15.7220435036 12845720 11780464 12973940
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 15.7217053015
MESH:D001749 Urinary Bladder Neoplasms Quercetin 15.7216720314
MESH:D001749 Urinary Bladder Neoplasms sodium arsenite 15.7211723127 16712894 16452187 17306315
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 15.7217572228 8653321 16712894
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 3.6510091137
MESH:D014581 Urticaria Acetaminophen 7.2110982225
MESH:D014581 Urticaria salmeterol 7.2110982225
MESH:D002583 Uterine Cervical Neoplasms resveratrol 12.4917473185
MESH:D002583 Uterine Cervical Neoplasms sodium arsenite 12.4911813266
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 12.4916129372
MESH:D014594 Uterine Neoplasms resveratrol 3.5017044934
MESH:D014604 Uveal Neoplasms Tretinoin 3.9316752155
MESH:D014605 Uveitis Cyclosporine 16.361336536
MESH:D014605 Uveitis Dexamethasone 16.361336536
MESH:D014605 Uveitis Zymosan 16.3611006244
MESH:D014652 Vascular Diseases sodium arsenite 3.7517056641
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 3.9112125929
MESH:D018487 Ventricular Dysfunction, Left Isoproterenol 8.5018097624
MESH:D018487 Ventricular Dysfunction, Left resveratrol 8.5017488730
MESH:D020257 Ventricular Remodeling Isoproterenol 5.0218097624
MESH:D014802 Vitamin A Deficiency Vitamin A 4.6516960172 16175781 16146918
MESH:D014820 Vitiligo Tretinoin 3.4216761959
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 3.5615886252
MESH:D015430 Weight Gain Dietary Fats 3.1616723640
MESH:D009396 Wilms Tumor Tretinoin 3.3916287080
MESH:D014985 Xerophthalmia Cyclosporine 3.7617120751
Pathway ID Pathway Name
KEGG:04920 Adipocytokine signaling pathway
REACT:15380 Diabetes pathways
KEGG:05016 Huntington's disease
KEGG:04910 Insulin signaling pathway
REACT:27166 Transcriptional Regulation of Adipocyte Differentiation in 3T3-L1 Pre-adipocytes
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA33558
    • No data
    Releated disease ID Related disease Name
    PA443890Diabetes Mellitus, Type 2
    Releated drug ID Related drug Name
    PA450970pioglitazone
    Drug Bank Top

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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