AutismKB 2.0

Annotation Detail for GADD45G


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:GADD45G ( CR6,DDIT2,GADD45gamma,GRP17 )
Gene Full Name: growth arrest and DNA-damage-inducible, gamma
Band: 9q22.2
Quick LinksEntrez ID:10912; OMIM: 604949; Uniprot ID:GA45G_HUMAN; ENSEMBL ID: ENSG00000130222; HGNC ID: 4097
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa04010MAPK signaling pathway
hsa04110Cell cycle
hsa04115p53 signaling pathway
No data
Pathway IDPathway Name
200034IL12-mediated signaling events
Pathway IDPathway Name
P00059p53 pathway
No data
Related Diseases/Disorders Top
No data
Desease IDDesease Name
2022Liver cancer
2169Pituitary tumor
Desease Name
protein quantitative trait loci
Desease Name
Protein quantitative trait loci
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C404910 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane results in increased expression of GADD45G mRNAincreases expression 20826375
C016617 2-nitropropane 2-nitropropane results in increased expression of GADD45G mRNAincreases expression 19268524
C016617 2-nitropropane APEX1 protein inhibits the reaction [2-nitropropane results in increased expression of GADD45G mRNA]decreases reaction|increases expression 19268524
C009505 4,4'-diaminodiphenylmethane 4,4'-diaminodiphenylmethane results in decreased expression of GADD45G mRNAdecreases expression 18648102
D000082 Acetaminophen Acetaminophen affects the expression of GADD45G mRNAaffects expression 17562736
15606129
D000638 Amiodarone Amiodarone results in increased expression of GADD45G mRNAincreases expression 19774075
D000643 Ammonium Chloride Ammonium Chloride affects the expression of GADD45G mRNAaffects expression 16483693
C050510 arsenic trichloride arsenic trichloride results in increased expression of GADD45G mRNAincreases expression 16283526
C050510 arsenic trichloride IKBKB affects the reaction [arsenic trichloride results in increased expression of GADD45G mRNA]affects reaction|increases expression 16283526
C006780 bisphenol A bisphenol A results in increased expression of GADD45G mRNAincreases expression 20826375
C057862 cyanoginosin LR cyanoginosin LR results in decreased expression of GADD45G mRNAdecreases expression 17383702
D016572 Cyclosporine Cyclosporine results in increased expression of GADD45G mRNAincreases expression 20106945
D003907 Dexamethasone [Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of GADD45G mRNAaffects cotreatment|increases expression 16054899
D003907 Dexamethasone [Tetrachlorodibenzodioxin co-treated with EGF protein] inhibits the reaction [[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of GADD45G mRNA]affects cotreatment|decreases reaction|increases expression 16054899
D003907 Dexamethasone Tetrachlorodibenzodioxin inhibits the reaction [[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of GADD45G mRNA]affects cotreatment|decreases reaction|increases expression 16054899
D004041 Dietary Fats Dietary Fats results in decreased expression of GADD45G mRNAdecreases expression 18042831
D004052 Diethylnitrosamine Diethylnitrosamine results in increased expression of GADD45G mRNAincreases expression 17942915
D004052 Diethylnitrosamine MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of GADD45G mRNA]decreases reaction|increases expression 17942915
D004317 Doxorubicin Doxorubicin results in increased expression of GADD45G mRNAincreases expression 16404146
D004958 Estradiol Estradiol affects the expression of GADD45G mRNAaffects expression 15598610
D004958 Estradiol Estradiol results in increased expression of GADD45G mRNAincreases expression 20826375
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of GADD45G mRNAaffects expression 17555576
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of GADD45G mRNAincreases expression 17942748
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of GADD45G mRNAaffects cotreatment|increases expression 17942748
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of GADD45G mRNAincreases expression 17351261
16174780
D005031 Ethylenethiourea Ethylenethiourea results in increased expression of GADD45G mRNAincreases expression 18801409
C419708 gefitinib gefitinib results in decreased expression of GADD45G mRNAdecreases expression 16685379
D015056 1-Methyl-3-isobutylxanthine [Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of GADD45G mRNAaffects cotreatment|increases expression 16054899
D015056 1-Methyl-3-isobutylxanthine [Tetrachlorodibenzodioxin co-treated with EGF protein] inhibits the reaction [[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of GADD45G mRNA]affects cotreatment|decreases reaction|increases expression 16054899
D015056 1-Methyl-3-isobutylxanthine Tetrachlorodibenzodioxin inhibits the reaction [[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of GADD45G mRNA]affects cotreatment|decreases reaction|increases expression 16054899
C533894 LG 100815 LG 100815 results in increased expression of GADD45G mRNAincreases expression 16951191
C030957 methylmercury II methylmercury II results in increased expression of GADD45G mRNAincreases expression 17905399
C062198 octa-2,4,6-trienoic acid octa-2,4,6-trienoic acid results in increased expression of GADD45G mRNAincreases expression 16951191
C042763 olive oil olive oil analog affects the expression of GADD45G mRNAaffects expression 17349074
D010126 Ozone Ozone results in increased expression of GADD45G mRNAincreases expression 19555225
C041786 palm oil palm oil results in decreased expression of GADD45G mRNAdecreases expression 18042831
D010269 Paraquat Paraquat results in increased expression of GADD45G mRNAincreases expression 12595580
15246999
C494474 perchlorate perchlorate results in increased expression of GADD45G mRNAincreases expression 18801409
C006253 pirinixic acid pirinixic acid results in decreased expression of GADD45G mRNAdecreases expression 17426115
C006253 pirinixic acid pirinixic acid results in increased expression of GADD45G mRNAincreases expression 18301758
20059764
18445702
16985257
C006253 pirinixic acid PPARA protein promotes the reaction [pirinixic acid results in increased expression of GADD45G mRNA]increases expression|increases reaction 20059764
D011374 Progesterone Progesterone affects the expression of GADD45G mRNAaffects expression 17251523
C089730 rosiglitazone [Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of GADD45G mRNAaffects cotreatment|increases expression 16054899
C089730 rosiglitazone [Tetrachlorodibenzodioxin co-treated with EGF protein] inhibits the reaction [[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of GADD45G mRNA]affects cotreatment|decreases reaction|increases expression 16054899
C089730 rosiglitazone Tetrachlorodibenzodioxin inhibits the reaction [[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of GADD45G mRNA]affects cotreatment|decreases reaction|increases expression 16054899
D012402 Rotenone Rotenone results in decreased expression of GADD45G mRNAdecreases expression 19013527
C064116 S-(1,1,2,2-tetrafluoroethyl)cysteine S-(1,1,2,2-tetrafluoroethyl)cysteine results in increased expression of GADD45G mRNAincreases expression 16678137
C017947 sodium arsenite sodium arsenite results in decreased expression of GADD45G mRNAdecreases expression 16014739
D013629 Tamoxifen Tamoxifen affects the expression of GADD45G mRNAaffects expression 17555576
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with EGF protein] inhibits the reaction [[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of GADD45G mRNA]affects cotreatment|decreases reaction|increases expression 16054899
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with EGF protein] results in decreased expression of GADD45G mRNAaffects cotreatment|decreases expression 16054899
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of GADD45G mRNAaffects cotreatment|increases expression 17942748
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin inhibits the reaction [[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of GADD45G mRNA]affects cotreatment|decreases reaction|increases expression 16054899
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of GADD45G mRNAincreases expression 16054899
D013849 Thimerosal Thimerosal results in increased expression of GADD45G mRNAincreases expression 16870260
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 4.1714745880
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 2.4915322242 14514962 11752688
MESH:D000138 Acidosis Ammonium Chloride 3.1918287403
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.5717505938
MESH:D055371 Acute Lung Injury pirinixic acid 2.7818653653
MESH:D000230 Adenocarcinoma Doxorubicin 9.3917418594
MESH:D000230 Adenocarcinoma Estradiol 9.3911473722
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 9.3914692618
MESH:D000230 Adenocarcinoma Ethylenethiourea 9.397955072
MESH:D000236 Adenoma 4,4'-diaminodiphenylmethane 5.953712494
MESH:D000236 Adenoma Diethylnitrosamine 5.956695378 10737359
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 15.1418056438 19052882 17620307 19061943 16434500 17162532
MESH:D018248 Adenoma, Liver Cell pirinixic acid 15.1416434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 15.1416835633
MESH:D000310 Adrenal Gland Neoplasms sodium arsenite 4.3215276417
MESH:D018246 Adrenocortical Adenoma sodium arsenite 4.5317306315 16712894
MESH:D000382 Agricultural Workers' Diseases Paraquat 3.4011874814
MESH:D000419 Albuminuria Doxorubicin 4.1921441931
MESH:D000544 Alzheimer Disease Ozone 4.1715513908
MESH:D000544 Alzheimer Disease rosiglitazone 4.1719621015
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.6311748828
MESH:D000799 Angioedema Acetaminophen 3.4710982225
MESH:D001145 Arrhythmias, Cardiac Amiodarone 3.4918218290 20041841 18057881
MESH:D001161 Arteriosclerosis Dietary Fats 8.7115238619
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 8.7111256880
MESH:D001169 Arthritis, Experimental Dexamethasone 6.6117659584
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 6.6115885639
MESH:D001172 Arthritis, Rheumatoid Ozone 2.4715570426
MESH:D001249 Asthma Ozone 2.5217854713 16373670
MESH:D050197 Atherosclerosis olive oil 4.1216216721
MESH:D001281 Atrial Fibrillation Amiodarone 3.6318651412 19698954
MESH:D001321 Autistic Disorder Acetaminophen 1.4618445737
MESH:D001660 Biliary Tract Diseases 4,4'-diaminodiphenylmethane 4.641440618 11289319
MESH:D001778 Blood Coagulation Disorders Amiodarone 13.4119483382
MESH:D001778 Blood Coagulation Disorders pirinixic acid 13.4119483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 13.4112125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.4215340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.5315746008
MESH:D019046 Bone Marrow Neoplasms Doxorubicin 4.3214601052
MESH:D001862 Bone Resorption bisphenol A 3.5411985600
MESH:D020201 Brain Hemorrhage, Traumatic Progesterone 4.9617868700
MESH:D001930 Brain Injuries Progesterone 3.9015665606 15380490 15845082
MESH:D001932 Brain Neoplasms Doxorubicin 3.4917150277
MESH:D001943 Breast Neoplasms bisphenol A 4.3917123778
MESH:D001943 Breast Neoplasms Dietary Fats 4.3920435547
MESH:D001943 Breast Neoplasms Diethylnitrosamine 4.3917474063
MESH:D001943 Breast Neoplasms Doxorubicin 4.3918628466 15634643 15136595 16115903 16264153 18234424 15939500 11325840 19526202 15567936 18695136 15994142 16096432 15692762 17369602 15993339 16322301 18382427 16826403 17983394 16935488 17426702 16595493 15668708
MESH:D001943 Breast Neoplasms Estradiol 4.3917289903 17018787 12948864 17261762 18497071 16675129 19861407 14630087
MESH:D001943 Breast Neoplasms Progesterone 4.3917614352 16175315 15562024
MESH:D001943 Breast Neoplasms Tamoxifen 4.3919103187 11161223 18425577 19221464 16818667 18815881 18821012 15668708 18997820 18855134 21152245 15565566 20065188 19142967 19487384 19115204 19066611 16202921 18984771 20544844 17049068 20135344 19244106 18629630 17440819 19189210 16873071 19155303 17242785 19289846 20859285 18351453 19059307 19011961 19200415 17893378 16273361 19288272 20005174 20390343 19189212 19084267 17261762 21138602 19410462
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 4.3920435547
MESH:D016535 Bronchial Hyperreactivity Ozone 3.3918315731 19059883 15516495 14754758 18417511 17626835 16777450
MESH:D002100 Cachexia Ozone 4.3716183385
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 4.0916111702
MESH:D002276 Carcinoid Tumor Doxorubicin 4.4416051944
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.5116835633
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 4.1519066611
MESH:D006528 Carcinoma, Hepatocellular 4,4'-diaminodiphenylmethane 13.033581430 7296757
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 13.033084413
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 13.0319383236 16502159 10737359 16328049 18665156 20727157 19418558 18788625 19822196 18978308 18056438 16878318 20007298 19171122 17428255 17138121 16540662 16569478 16830150 19539802 18210153 17978847 20084675 10672840 20935162 17761372 18691550 16288022 19394651 17173139 19519916 3084413 11831363 19919837 20524982 20514400 20101231 18393292 16779866 19701751 16807293 16935385 3581430 20214788 19052882 19208518 20512989 17055752 21159647 18506893 16681979 19335982 18494052 19107877 16698587 17162532 20432363 18971187 18785209
MESH:D006528 Carcinoma, Hepatocellular Doxorubicin 13.0318059187 17876044 16234567 16023760
MESH:D006528 Carcinoma, Hepatocellular Estradiol 13.0316924424
MESH:D006528 Carcinoma, Hepatocellular sodium arsenite 13.0316507464 17306315 15276417
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 13.0316924424
MESH:D002278 Carcinoma in Situ bisphenol A 4.6217123778
MESH:D002289 Carcinoma, Non-Small-Cell Lung gefitinib 3.8218347146 16230376 20005069 17290066 15496427 19233551
MESH:D002292 Carcinoma, Renal Cell 4,4'-diaminodiphenylmethane 5.957296757
MESH:D002292 Carcinoma, Renal Cell Doxorubicin 5.9516201981 1485588
MESH:D002294 Carcinoma, Squamous Cell Doxorubicin 4.436189445
MESH:D002294 Carcinoma, Squamous Cell sodium arsenite 4.4318572023
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 3.3017572228
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.1618850075 18670907 16120746
MESH:D009202 Cardiomyopathies Doxorubicin 3.2916278810 15476868 16952015 16731534 17007740 16269455 17924179 16109756 16455267 16651473 17928571 17519947 17974986 17308081 16242529 18627295 16612575 16364871 15811867 17329180 17382496 17131338 15792986 15505089 17351982
MESH:D002311 Cardiomyopathy, Dilated Amiodarone 5.5315710769 19225199
MESH:D002311 Cardiomyopathy, Dilated Doxorubicin 5.5317334414 16243910
MESH:D002318 Cardiovascular Diseases olive oil 4.2916216721
MESH:D002341 Carotid Artery Thrombosis Amiodarone 4.7218974383
MESH:D002386 Cataract Acetaminophen 2.3610977129
MESH:D002471 Cell Transformation, Neoplastic 4,4'-diaminodiphenylmethane 18.407505956
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 18.4012371664
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 18.4017174075 21159647 2727394 7505956
MESH:D002471 Cell Transformation, Neoplastic Estradiol 18.4018566989
MESH:D002471 Cell Transformation, Neoplastic sodium arsenite 18.4020056578 19524636
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 8.3019052882
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 8.3016835633
MESH:D002779 Cholestasis 4,4'-diaminodiphenylmethane 16.9919486331 9022650
MESH:D002779 Cholestasis Cyclosporine 16.9919486331
MESH:D002779 Cholestasis Ethinyl Estradiol 16.9917110522 15861022 17681005 17333356 16105132 11677210 16919318
MESH:D002779 Cholestasis pirinixic acid 16.9919176532
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 1.958697196 15340226 15668235 16354765 12621046
MESH:D003110 Colonic Neoplasms Dexamethasone 2.4315824018
MESH:D015179 Colorectal Neoplasms Doxorubicin 3.0118802399 18259882
MESH:D015179 Colorectal Neoplasms gefitinib 3.0117594712
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 2.7517141729 14669216
MESH:D019465 Craniofacial Abnormalities Dexamethasone 2.4917728286
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 2.4915322242 20055451 10048152
MESH:D003711 Demyelinating Diseases Tamoxifen 4.0019031437
MESH:D017449 Dermatitis, Allergic Contact 4,4'-diaminodiphenylmethane 9.7418759878 14531868 8156756 2524372 12868966 11906362 11298694 8970840
MESH:D017449 Dermatitis, Allergic Contact Dexamethasone 9.7412438553
MESH:D017449 Dermatitis, Allergic Contact Thimerosal 9.7416958921 15932584
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.2518249437
MESH:D003877 Dermatitis, Contact 4,4'-diaminodiphenylmethane 3.153621924 2952479
MESH:D002658 Developmental Disabilities Thimerosal 4.5915764492
MESH:D003920 Diabetes Mellitus rosiglitazone 3.9917446233
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 6.5720387270
MESH:D003924 Diabetes Mellitus, Type 2 rosiglitazone 6.5712642470
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 6.5717107852
MESH:D003928 Diabetic Nephropathies Estradiol 7.8219279558
MESH:D003928 Diabetic Nephropathies Tamoxifen 7.8219279558
MESH:D003929 Diabetic Neuropathies Progesterone 4.1317187935
MESH:D003967 Diarrhea Dexamethasone 3.367237001
MESH:D056486 Drug-Induced Liver Injury 2-nitropropane 20.1115804453 16445897 20517888
MESH:D056486 Drug-Induced Liver Injury 4,4'-diaminodiphenylmethane 20.1118289764 7440962 18692083 9022650 6679447 9653073 6482804 8291058 9328219 18648102 1440618 11289319 16192314
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 20.1115619225 19416960 16485898 16177239 10663392 16227642 16393943 11421492 12594235 12705907 19370779 16081117 19164858 16781746 18713872 14986274 19420014 18071297 11739529 15968718 17562736 19085960 11743745 10774834 19923254 11461765 2444490 12958197 12392966 14725611 12153990 17522070 19739265 16109766 11529661 11834606 11287661 17906064 10915739 12540782 14550746
MESH:D056486 Drug-Induced Liver Injury Amiodarone 20.1115265979 18218290
MESH:D056486 Drug-Induced Liver Injury cyanoginosin LR 20.1117654400
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 20.1119107877
MESH:D056486 Drug-Induced Liver Injury Doxorubicin 20.1117416283
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 20.1120420201
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 3.7219426721
MESH:D004362 Drug Toxicity Doxorubicin 7.2118602426
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 7.2111462148
MESH:D050171 Dyslipidemias Dietary Fats 3.1918367378
MESH:D004485 Eczema Dexamethasone 4.1112438553
MESH:D004487 Edema Dexamethasone 13.7919703484
MESH:D004487 Edema pirinixic acid 13.7912083418
MESH:D004487 Edema rosiglitazone 13.7912083418
MESH:D004487 Edema Tetrachlorodibenzodioxin 13.7912711302 11000095
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.5315322242 16714409 18230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 13.3012538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Progesterone 13.3017692515
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 13.3019031437
MESH:D016889 Endometrial Neoplasms Doxorubicin 15.8817359293
MESH:D016889 Endometrial Neoplasms Estradiol 15.8818566989 11473722 19148513
MESH:D016889 Endometrial Neoplasms Ethylenethiourea 15.887955072
MESH:D016889 Endometrial Neoplasms Tamoxifen 15.8819155303 16202921 17893378 20544844
MESH:D004715 Endometriosis Progesterone 7.8716134523
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 7.8710568697 9294722
MESH:D004719 Endomyocardial Fibrosis Doxorubicin 4.7818037988
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 4.7416302075
MESH:D004938 Esophageal Neoplasms 4,4'-diaminodiphenylmethane 2.013581430
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 2.7411564622
MESH:D005234 Fatty Liver Amiodarone 37.5914986274
MESH:D005234 Fatty Liver Cyclosporine 37.5919224547
MESH:D005234 Fatty Liver Dietary Fats 37.5917967931 18296743 19004024 19551842
MESH:D005234 Fatty Liver Diethylnitrosamine 37.5920387270 21071580
MESH:D005234 Fatty Liver Ethinyl Estradiol 37.5915345470
MESH:D005234 Fatty Liver pirinixic acid 37.5920131406 19236843
MESH:D005234 Fatty Liver rosiglitazone 37.5919196556
MESH:D005234 Fatty Liver Tamoxifen 37.5919224547 14986274
MESH:D052776 Female Urogenital Diseases Tamoxifen 3.0116709447
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.1011858732
MESH:D005350 Fibroma 4,4'-diaminodiphenylmethane 4.646705139
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 4.1614745880
MESH:D018222 Fibromatosis, Aggressive Doxorubicin 10.2119069698
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 10.2119069698
MESH:D005355 Fibrosis Cyclosporine 12.6412639820 12168785
MESH:D005355 Fibrosis Dietary Fats 12.6418296743
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 12.6420067830
MESH:D005756 Gastritis Acetaminophen 3.3016983495
MESH:D005833 Genital Neoplasms, Female sodium arsenite 4.3116452187
MESH:D005885 Gingival Hyperplasia Cyclosporine 3.858708960
MESH:D005909 Glioblastoma Doxorubicin 3.1117150277
MESH:D005911 Gliosis Paraquat 4.7911124998
MESH:D006042 Goiter 4,4'-diaminodiphenylmethane 10.357505956
MESH:D006042 Goiter perchlorate 10.3518801409
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.2210696789
MESH:D006258 Head and Neck Neoplasms Doxorubicin 3.2815692506
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 2.1310048152 11294989
MESH:D006331 Heart Diseases Doxorubicin 3.2316244371 16879835 12587719 17875725 16330681 16244372 17888722 18006777 16707910 14766674 18674790 16495754 16144979
MESH:D006333 Heart Failure Doxorubicin 6.2917481944
MESH:D006333 Heart Failure pirinixic acid 6.2920558911
MESH:D006394 Hemangiosarcoma Doxorubicin 3.5715692506
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.0515720958
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.0111000095
MESH:D006505 Hepatitis 4,4'-diaminodiphenylmethane 3.176705139
MESH:D006529 Hepatomegaly Amiodarone 12.3415265979
MESH:D006529 Hepatomegaly pirinixic acid 12.3418467677 19772884 19176532 16221962
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 12.3412621046 16120746 15340226
MESH:D006548 Hernia, Diaphragmatic Dexamethasone 2.947520565
MESH:D006558 Herpes Genitalis Estradiol 4.6615709030
MESH:D006689 Hodgkin Disease Doxorubicin 6.4715147373 17606976 18501091
MESH:D006689 Hodgkin Disease sodium arsenite 6.4712676792
MESH:D019584 Hot Flashes Estradiol 3.3817088409
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.6716959395 16354765 15340226 18606429 8697196
MESH:D006930 Hyperalgesia Acetaminophen 6.9316870215
MESH:D006930 Hyperalgesia rosiglitazone 6.9312083418
MESH:D006937 Hypercholesterolemia Amiodarone 8.088137927 9751232
MESH:D006937 Hypercholesterolemia Dietary Fats 8.0821332399
MESH:D006943 Hyperglycemia pirinixic acid 2.8720558911
MESH:D006949 Hyperlipidemias Dietary Fats 3.2821332399
MESH:D006965 Hyperplasia 4,4'-diaminodiphenylmethane 3.5815034207
MESH:D006973 Hypertension Cyclosporine 7.7210903974
MESH:D006973 Hypertension Dexamethasone 7.7217042910
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 7.7218850075 18670907
MESH:D006976 Hypertension, Pulmonary gefitinib 4.4318424623
MESH:D017380 Hypertrophy, Right Ventricular gefitinib 5.8718424623
MESH:D007021 Hypospadias Ethinyl Estradiol 3.4516945680 16569931
MESH:D007037 Hypothyroidism Amiodarone 4.1517991464 18020914
MESH:D007077 Ileal Diseases 1-Methyl-3-isobutylxanthine 5.0718306037
MESH:D020244 Infarction, Middle Cerebral Artery Progesterone 4.0415869954
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.1212013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 9.8117937319
MESH:D007248 Infertility, Male Paraquat 9.814850670
MESH:D007248 Infertility, Male sodium arsenite 9.8112646999 15346721
MESH:D007249 Inflammation Dexamethasone 21.2211099482 8960868
MESH:D007249 Inflammation Dietary Fats 21.2220412841
MESH:D007249 Inflammation Diethylnitrosamine 21.2218785209
MESH:D007249 Inflammation Progesterone 21.2215869954
MESH:D007249 Inflammation rosiglitazone 21.2212083418
MESH:D007249 Inflammation Tamoxifen 21.2219457130
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 21.2212878042 12200463
MESH:D007333 Insulin Resistance bisphenol A 20.6316393666
MESH:D007333 Insulin Resistance Dietary Fats 20.6311836018 18457598
MESH:D007333 Insulin Resistance Estradiol 20.6316393666 16627594
MESH:D007333 Insulin Resistance pirinixic acid 20.6316306350
MESH:D007333 Insulin Resistance rosiglitazone 20.6316306350
MESH:D007565 Jaundice 4,4'-diaminodiphenylmethane 4.648074119 9022650
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 3.0116580747
MESH:D007579 Jejunal Diseases 1-Methyl-3-isobutylxanthine 5.0718306037
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.0715604871
MESH:D007674 Kidney Diseases Acetaminophen 16.7612587719 15629191
MESH:D007674 Kidney Diseases Cyclosporine 16.768314463 10903974 18776723
MESH:D007674 Kidney Diseases Doxorubicin 16.7615699352 15369732 16775033
MESH:D007674 Kidney Diseases Estradiol 16.7615618244
MESH:D007674 Kidney Diseases sodium arsenite 16.7620008137
MESH:D007676 Kidney Failure, Chronic Doxorubicin 3.8316707910
MESH:D007680 Kidney Neoplasms 4,4'-diaminodiphenylmethane 20.216582329
MESH:D007680 Kidney Neoplasms Cyclosporine 20.2112371664
MESH:D007680 Kidney Neoplasms Estradiol 20.2115610895
MESH:D007680 Kidney Neoplasms gefitinib 20.2118625569
MESH:D007680 Kidney Neoplasms Tamoxifen 20.2118625569
MESH:D004915 Leukemia, Erythroblastic, Acute Doxorubicin 4.7816085563
MESH:D008064 Lipidoses Amiodarone 7.0417567588 15342952
MESH:D008064 Lipidoses Tamoxifen 7.0415342952 17567588
MESH:D008103 Liver Cirrhosis Dietary Fats 5.9518296743
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 5.9518665156 18407596 18522880 19638242 20032147
MESH:D008105 Liver Cirrhosis, Biliary 4,4'-diaminodiphenylmethane 2.979327722 15034207
MESH:D008106 Liver Cirrhosis, Experimental Dexamethasone 10.1016718785
MESH:D008106 Liver Cirrhosis, Experimental Doxorubicin 10.1016439617 16595196
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 10.1014716833 14659978
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 10.1015474484
MESH:D008106 Liver Cirrhosis, Experimental rosiglitazone 10.1017347453 15980055
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 10.1018564211
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 10.1012878042
MESH:D008107 Liver Diseases Acetaminophen 3.5612969438 16610002 19784758 12587719 19460945 11587558 19014921 16611625
MESH:D008107 Liver Diseases Diethylnitrosamine 3.5617034775
MESH:D017114 Liver Failure, Acute Acetaminophen 2.9216871587 17185352
MESH:D008113 Liver Neoplasms Diethylnitrosamine 16.0521278145 18754104 19812893 21167192 19426721 19256749 19690152 19996281 12112319 16942905 15175105 19255062 20452335 10737359 20137499 19427195 12771043 2422723 19499222 20118626 18648771 21047994 19254457 20492335 19638242 21071580 18977376 18644402 20101389 19551842 2862719 19833225 19294768 20501860 18978307 19090486 15885732 20583210 20405173 19850985 19073162 19642983 20434301 9163691
MESH:D008113 Liver Neoplasms Ethylenethiourea 16.0511940454
MESH:D008113 Liver Neoplasms pirinixic acid 16.0515890375 20007298 16377806
MESH:D008113 Liver Neoplasms sodium arsenite 16.0516712894 15276417
MESH:D008113 Liver Neoplasms Tamoxifen 16.0516684651
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 16.0516984957
MESH:D008114 Liver Neoplasms, Experimental 4,4'-diaminodiphenylmethane 12.21598648 6587162 3712494 1399818
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 12.2119126423 18544905 18164116 18775883 18282651 18079962 17942915 16842330 3124819 19009564 2563599 9362446 21159647 16267830 19004024 19539802 17174075 19519916 17854601 18308698 18093689 18253720
MESH:D008114 Liver Neoplasms, Experimental Doxorubicin 12.2117085340 16842330
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 12.2112151625
MESH:D008133 Long QT Syndrome Amiodarone 3.3017391786 15350150 11989578
MESH:D008171 Lung Diseases Amiodarone 10.9612587719
MESH:D008171 Lung Diseases Ozone 10.968266340 19066396
MESH:D008171 Lung Diseases sodium arsenite 10.9619095001
MESH:D017563 Lung Diseases, Interstitial Amiodarone 4.1018516814
MESH:D055370 Lung Injury Ozone 3.4920417186
MESH:D008175 Lung Neoplasms Dexamethasone 9.8915824018 11195469
MESH:D008175 Lung Neoplasms Diethylnitrosamine 9.8920512841 20970405 6695378 21163286
MESH:D008175 Lung Neoplasms Doxorubicin 9.8917418594 6189445
MESH:D008175 Lung Neoplasms Ozone 9.898597069 7614698
MESH:D008175 Lung Neoplasms sodium arsenite 9.8917306315 15276417 16712894 17077188 19931552
MESH:D008175 Lung Neoplasms Tamoxifen 9.8918625569
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 9.8911884234 19555203
MESH:D008223 Lymphoma Doxorubicin 3.2016098063
MESH:D008228 Lymphoma, Non-Hodgkin Doxorubicin 3.4917654614
MESH:D016399 Lymphoma, T-Cell Doxorubicin 4.2115621674
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 3.3919428831
MESH:D008325 Mammary Neoplasms, Experimental Doxorubicin 20.4915458769
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 20.4911807958 16891317 11408345 17203775
MESH:D008325 Mammary Neoplasms, Experimental gefitinib 20.4918375820
MESH:D008325 Mammary Neoplasms, Experimental Progesterone 20.4911408345 17203775
MESH:D008325 Mammary Neoplasms, Experimental rosiglitazone 20.4916827153
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 20.4914580682 19196722 11731420 19196723 16827153
MESH:D020149 Manganese Poisoning Estradiol 11.4019453300
MESH:D020149 Manganese Poisoning Tamoxifen 11.4019453300
MESH:D008545 Melanoma Doxorubicin 4.7116827129
MESH:D008545 Melanoma sodium arsenite 4.7119082730 16487513
MESH:D008545 Melanoma Tamoxifen 4.7112393984 19393235
MESH:D018328 Melanoma, Amelanotic Tamoxifen 3.8115990972
MESH:D008546 Melanoma, Experimental Acetaminophen 3.2119513568
MESH:D008654 Mesothelioma Doxorubicin 2.9117638057
MESH:D024821 Metabolic Syndrome X rosiglitazone 4.0817261469
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.4116801185
MESH:D008679 Metaplasia Ozone 4.7310496685
MESH:D028361 Mitochondrial Diseases Doxorubicin 4.1715792986
MESH:D052016 Mucositis Doxorubicin 4.4217415656
MESH:D009101 Multiple Myeloma Dexamethasone 3.2515867202 16118317 15744524
MESH:D009135 Muscular Diseases pirinixic acid 3.1516239165
MESH:D009181 Mycoses Amiodarone 4.5312754197 17974566
MESH:D009190 Myelodysplastic Syndromes Dexamethasone 3.339809623
MESH:D009203 Myocardial Infarction Doxorubicin 5.1815857846 19429709
MESH:D009203 Myocardial Infarction pirinixic acid 5.1819151258
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 2.7312213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 7.3216810080
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 7.3216411023
MESH:D009336 Necrosis 2-nitropropane 5.1912195237
MESH:D009362 Neoplasm Metastasis 4,4'-diaminodiphenylmethane 12.303581430
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 12.303581430 9029167
MESH:D009362 Neoplasm Metastasis Doxorubicin 12.3018259882
MESH:D009362 Neoplasm Metastasis Tamoxifen 12.3019393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.3919410462
MESH:D009369 Neoplasms pirinixic acid 4.3217405874
MESH:D009369 Neoplasms sodium arsenite 4.3211559025
MESH:D009374 Neoplasms, Experimental sodium arsenite 3.3120056578
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 3.6319196722 19189210 19200415
MESH:D009389 Neovascularization, Pathologic Estradiol 3.3717289903
MESH:D009401 Nephrosis Doxorubicin 4.4116636307 16899518
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.0717954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 8.2719348381 18481113
MESH:D009404 Nephrotic Syndrome Doxorubicin 8.2715640375 16889571
MESH:D009410 Nerve Degeneration Paraquat 7.7116893418
MESH:D009410 Nerve Degeneration Rotenone 7.7118619942 15790535 17356569
MESH:D009421 Nervous System Malformations bisphenol A 14.3311399458 16427766
MESH:D009421 Nervous System Malformations Estradiol 14.3311399458 16427766
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 14.3314600291
MESH:D009436 Neural Tube Defects 4,4'-diaminodiphenylmethane 6.466679447
MESH:D009436 Neural Tube Defects sodium arsenite 6.4612854658
MESH:D009447 Neuroblastoma Doxorubicin 3.0715555623
MESH:D019636 Neurodegenerative Diseases Acetaminophen 7.1918514411
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 7.1920387270
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 4.7420387270
MESH:D009765 Obesity Dietary Fats 4.0918457598 21332399 20132043 17217161 18674790 20518802 19632207 11836018 16723640
MESH:D009765 Obesity pirinixic acid 4.0920558911
MESH:D009784 Occupational Diseases 4,4'-diaminodiphenylmethane 3.104026338 6482804
MESH:D009902 Optic Neuritis 4,4'-diaminodiphenylmethane 4.643988306
MESH:D012516 Osteosarcoma Doxorubicin 3.8215930896
MESH:D010049 Ovarian Diseases bisphenol A 4.6211985600
MESH:D010051 Ovarian Neoplasms Estradiol 7.1619401270
MESH:D010051 Ovarian Neoplasms Progesterone 7.1617393432 16525653
MESH:D010051 Ovarian Neoplasms sodium arsenite 7.1617306315 15276417
MESH:D010146 Pain Acetaminophen 2.1116870215
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 2.2916540662
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.3511578682
MESH:D010212 Papilloma 4,4'-diaminodiphenylmethane 3.137296757
MESH:D010300 Parkinson Disease Paraquat 5.1011445065 11181820 15451049 11124998 12911755 15824117 16140633 16510128
MESH:D010300 Parkinson Disease Rotenone 5.1019114014 16140633 11535288 18619942 11445065 16412576 15451049 19232380 18191903
MESH:D010302 Parkinson Disease, Secondary Paraquat 4.0716190885
MESH:D020734 Parkinsonian Disorders Rotenone 3.7615795934 18197244 15927086 15574749
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 3.8712520081
MESH:D010538 Peritonitis Ozone 3.7716369182
MESH:D010787 Photosensitivity Disorders 4,4'-diaminodiphenylmethane 4.106228378
MESH:D003557 Phyllodes Tumor Doxorubicin 4.7817983394
MESH:D010997 Pleural Neoplasms Doxorubicin 4.7817638057
MESH:D011014 Pneumonia Ozone 9.8418007984 18929643 18381685
MESH:D011014 Pneumonia Paraquat 9.8412504350
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.2118163543
MESH:D011230 Precancerous Conditions Cyclosporine 7.9212371664
MESH:D011230 Precancerous Conditions Diethylnitrosamine 7.922563599
MESH:D054198 Precursor Cell Lymphoblastic Leukemia-Lymphoma Dexamethasone 3.3421297632
MESH:D011297 Prenatal Exposure Delayed Effects bisphenol A 8.2910548101
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 8.2911118676 11896295 11222880 11399792
MESH:D019048 Prostatic Intraepithelial Neoplasia bisphenol A 9.4620887781
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 9.4620887781
MESH:D011471 Prostatic Neoplasms bisphenol A 1.8816740699
MESH:D011471 Prostatic Neoplasms Doxorubicin 1.8816868541 18437689 15749863 15897917 16888761 16729912
MESH:D011471 Prostatic Neoplasms Estradiol 1.8816740699
MESH:D011471 Prostatic Neoplasms gefitinib 1.8817914592 15651060 16685379
MESH:D011471 Prostatic Neoplasms sodium arsenite 1.8816039940
MESH:D011471 Prostatic Neoplasms Tamoxifen 1.8815067354
MESH:D011537 Pruritus Ethinyl Estradiol 2.9516919318 15861022
MESH:D011565 Psoriasis Cyclosporine 2.1016882103
MESH:D011629 Puberty, Precocious bisphenol A 4.4210548101
MESH:D011658 Pulmonary Fibrosis Amiodarone 8.6112490602 11597910 12832656
MESH:D011658 Pulmonary Fibrosis gefitinib 8.6118424623
MESH:D011658 Pulmonary Fibrosis Paraquat 8.6117997886 16324872
MESH:D051437 Renal Insufficiency Doxorubicin 3.8617922066
MESH:D015427 Reperfusion Injury pirinixic acid 2.2019058328
MESH:D012128 Respiratory Distress Syndrome, Adult Dexamethasone 8.1418379247 11700416
MESH:D012128 Respiratory Distress Syndrome, Adult Paraquat 8.1411700416
MESH:D012135 Respiratory Sounds Paraquat 3.7011874814
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.4918990726
MESH:D012162 Retinal Degeneration 4,4'-diaminodiphenylmethane 8.013692021
MESH:D012162 Retinal Degeneration Paraquat 8.0116458197
MESH:D012468 Salivary Gland Neoplasms Progesterone 2.7218045962
MESH:D012509 Sarcoma Doxorubicin 3.6716767912 15675481 18313854 17710206 15625365 17203757
MESH:D012512 Sarcoma, Ewing's Doxorubicin 3.8914601052 16326096
MESH:D012514 Sarcoma, Kaposi Doxorubicin 4.4217846226
OMIM:609620 SHORT QT SYNDROME 1 Amiodarone 4.7218724381
MESH:D012878 Skin Neoplasms Doxorubicin 8.4315692506
MESH:D012878 Skin Neoplasms sodium arsenite 8.4318572023 19524636
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 8.4316192470
MESH:D012983 Soft Tissue Neoplasms Doxorubicin 4.2116767912 17203757 15625365
MESH:D013088 Spermatocele Ethinyl Estradiol 10.3116709447
MESH:D013088 Spermatocele Tamoxifen 10.3116709447
MESH:D013119 Spinal Cord Injuries Progesterone 9.6516503802 15862959
MESH:D013119 Spinal Cord Injuries Tamoxifen 9.6519457130
MESH:D016135 Spinal Dysraphism sodium arsenite 3.5112854658
MESH:D013272 Stomach Diseases Dexamethasone 3.9515472012
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 1.7518456281
MESH:D013276 Stomach Ulcer Amiodarone 10.4218087811
MESH:D013276 Stomach Ulcer Dexamethasone 10.4215138204
MESH:D013276 Stomach Ulcer olive oil 10.4216252198 12498302
MESH:D019966 Substance-Related Disorders bisphenol A 3.6216684133 16045194
MESH:D013610 Tachycardia Amiodarone 3.9411238279
MESH:D017180 Tachycardia, Ventricular Amiodarone 3.8419225199
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.2811994571
MESH:D013927 Thrombosis Ethinyl Estradiol 2.8515669648
MESH:D013959 Thyroid Diseases Amiodarone 10.8019731979
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 10.8012697716
MESH:D013964 Thyroid Neoplasms 4,4'-diaminodiphenylmethane 19.586582329 3712494 6587162 1399818 7505956
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 19.587505956
MESH:D013964 Thyroid Neoplasms Doxorubicin 19.5816010429 17909728
MESH:D013964 Thyroid Neoplasms Ethylenethiourea 19.5811940454
MESH:D013964 Thyroid Neoplasms gefitinib 19.5816940797
MESH:D013971 Thyrotoxicosis Amiodarone 4.5018020914 19584973
MESH:D013978 Tibial Fractures Estradiol 4.3119048282
MESH:D016171 Torsades de Pointes Amiodarone 3.8217467628 11989578
MESH:D001749 Urinary Bladder Neoplasms 4,4'-diaminodiphenylmethane 10.688074119
MESH:D001749 Urinary Bladder Neoplasms Doxorubicin 10.6817653716
MESH:D001749 Urinary Bladder Neoplasms sodium arsenite 10.6817306315 11723127 16712894 16452187
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 10.6816712894 8653321 17572228
MESH:D014581 Urticaria Acetaminophen 2.6410982225
MESH:D002583 Uterine Cervical Neoplasms sodium arsenite 3.4511813266
MESH:D014591 Uterine Diseases bisphenol A 4.6314652134
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 2.9514692618
MESH:D014605 Uveitis Cyclosporine 10.521336536
MESH:D014605 Uveitis Dexamethasone 10.521336536
MESH:D014652 Vascular Diseases sodium arsenite 4.0617056641
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.2212125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.2114671159 15869587
MESH:D018487 Ventricular Dysfunction, Left Doxorubicin 3.8617334414 16364871 17678736 17638931
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 3.8715886252
MESH:D015430 Weight Gain Dietary Fats 3.4316723640
MESH:D014985 Xerophthalmia Cyclosporine 4.0717120751
Pathway ID Pathway Name
KEGG:04110 Cell cycle
KEGG:04010 MAPK signaling pathway
KEGG:04115 p53 signaling pathway
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA28512
    • No data
    Releated disease ID Related disease Name
    PA445742Stomach Neoplasms
    Releated drug ID Related drug Name
    PA449957ibuprofen
    Drug Bank Top

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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