AutismKB 2.0

Annotation Detail for HNRNPA0


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Basic Information Top
Gene Symbol:HNRNPA0 ( HNRPA0 )
Gene Full Name: heterogeneous nuclear ribonucleoprotein A0
Band: 5q31.2
Quick LinksEntrez ID:10949; OMIM: 609409; Uniprot ID:ROA0_HUMAN; ENSEMBL ID: ENSG00000177733; HGNC ID: 5030
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
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Pathway IDPathway Name
mRNA Processing
Gene Expression
No data
No data
Pathway IDPathway Name
500866mRNA Splicing - Major Pathway
500655Processing of Capped Intron-Containing Pre-mRNA
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000082 Acetaminophen Acetaminophen affects the expression of HNRNPA0 mRNAaffects expression 17562736
D001564 Benzo(a)pyrene Benzo(a)pyrene results in decreased expression of HNRNPA0 mRNAdecreases expression 17879257
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of HNRNPA0 mRNAdecreases expression 19150397
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 2.0620127859 20464547
MESH:D000236 Adenoma Benzo(a)pyrene 2.886695378
MESH:D000799 Angioedema Acetaminophen 4.7110982225
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 4.7319183758
MESH:D001321 Autistic Disorder Acetaminophen 1.3918445737
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 1.9917474063 20146248
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 1.413084413
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 2.1420419170
MESH:D002386 Cataract Acetaminophen 2.8110977129
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 3.0120889678
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 1.6816485898 12392966 19164858 12540782 12594235 10774834 16393943 19923254 19370779 2444490 17562736 12153990 11461765 11529661 10915739 14550746 16227642 15619225 12705907 19420014 14725611 11739529 17906064 10663392 17522070 11743745 14986274 18713872 15968718 16177239 16081117 19416960 18071297 16781746 19739265 19085960 11287661 16109766 11834606 12958197 11421492
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.9619426721
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 4.6420426865
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 4.6416530937
MESH:D005756 Gastritis Acetaminophen 4.5416983495
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 2.8520471113
MESH:D006930 Hyperalgesia Acetaminophen 3.0616870215
MESH:D007674 Kidney Diseases Acetaminophen 2.4215629191 12587719
MESH:D008107 Liver Diseases Acetaminophen 1.7119784758 11587558 19014921 12587719 12969438 16611625 19460945 16610002
MESH:D017114 Liver Failure, Acute Acetaminophen 3.6817185352 16871587
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 2.1720195826 21137059
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 1.5718520028 20464547 20135361 18569708 6695378 18816296 20869020 17053015 20064080
MESH:D008546 Melanoma, Experimental Acetaminophen 4.2219513568
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 3.5316381670
MESH:D009369 Neoplasms Benzo(a)pyrene 2.3511141357
MESH:D019636 Neurodegenerative Diseases Acetaminophen 3.2618514411
MESH:D010146 Pain Acetaminophen 2.7716870215
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 2.9017292933
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 2.5419755658 10029692
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 1.562093021 20155912
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 2.3117053015
MESH:D014581 Urticaria Acetaminophen 3.5010982225
Pathway ID Pathway Name
REACT:71 Gene Expression
REACT:1675 mRNA Processing
Pharmacogenomics Knowledge Base Top
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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018