AutismKB 2.0

Annotation Detail for BTG3


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:BTG3 ( ANA,MGC8928,TOB5,TOB55,TOFA )
Gene Full Name: BTG family, member 3
Band: 21q21.1
Quick LinksEntrez ID:10950; OMIM: 605674; Uniprot ID:BTG3_HUMAN; ENSEMBL ID: ENSG00000154640; HGNC ID: 1132
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of BTG3 mRNAaffects expression 21346803
C026137 3-hydroxyacetanilide 3-hydroxyacetanilide results in increased expression of BTG3 mRNAincreases expression 18544908
D000082 Acetaminophen Acetaminophen affects the expression of BTG3 mRNAaffects expression 17562736
D000082 Acetaminophen Acetaminophen results in increased expression of BTG3 mRNAincreases expression 18544908
D016604 Aflatoxin B1 Aflatoxin B1 affects the expression of BTG3 proteinaffects expression 20106945
D000643 Ammonium Chloride Ammonium Chloride affects the expression of BTG3 mRNAaffects expression 16483693
D019324 beta-Naphthoflavone [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of BTG3 mRNAaffects cotreatment|increases expression 18164116
D001564 Benzo(a)pyrene Benzo(a)pyrene results in increased expression of BTG3 mRNAincreases expression 20106945
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased expression of BTG3 mRNAincreases expression 19150397
D003520 Cyclophosphamide BTG3 mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide]affects cotreatment|affects response to substance 16896004
D016572 Cyclosporine Cyclosporine results in increased expression of BTG3 mRNAincreases expression 20106945
C014347 decitabine decitabine results in decreased methylation of BTG3 promoterdecreases methylation 19221000
C014347 decitabine decitabine results in increased expression of BTG3 mRNAincreases expression 19221000
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of BTG3 mRNAaffects cotreatment|increases expression 18164116
D004317 Doxorubicin BTG3 mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide]affects cotreatment|affects response to substance 16896004
D004958 Estradiol Estradiol results in increased expression of BTG3 mRNAincreases expression 20106945
D005472 Fluorouracil BTG3 mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide]affects cotreatment|affects response to substance 16896004
D019833 Genistein Genistein results in decreased methylation of BTG3 promoterdecreases methylation 19221000
D019833 Genistein Genistein results in increased expression of BTG3 mRNAincreases expression 19221000
C008493 methylselenic acid methylselenic acid results in increased expression of BTG3 mRNAincreases expression 18548127
C014707 nitrosobenzylmethylamine nitrosobenzylmethylamine results in increased expression of BTG3 mRNAincreases expression 17616710
D017239 Paclitaxel BTG3 mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide]affects cotreatment|affects response to substance 16896004
D010656 Phenylephrine Phenylephrine results in increased expression of BTG3 mRNAincreases expression 18158353
C006253 pirinixic acid pirinixic acid results in increased expression of BTG3 mRNAincreases expression 18445702
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000138 Acidosis Ammonium Chloride 3.4518287403
MESH:D055371 Acute Lung Injury pirinixic acid 3.0118653653
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 13.2620127859 20464547
MESH:D000230 Adenocarcinoma Doxorubicin 13.2617418594
MESH:D000230 Adenocarcinoma Estradiol 13.2611473722
MESH:D000230 Adenocarcinoma Fluorouracil 13.2617638652
MESH:D000230 Adenocarcinoma Genistein 13.2611473722
MESH:D000236 Adenoma Benzo(a)pyrene 10.846695378
MESH:D000236 Adenoma beta-Naphthoflavone 10.8419389873
MESH:D000236 Adenoma Diethylnitrosamine 10.846695378 10737359
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 9.7316434500 19052882 17162532 19061943 17620307 18056438
MESH:D018248 Adenoma, Liver Cell pirinixic acid 9.7316434500
MESH:D000419 Albuminuria Doxorubicin 4.4421441931
MESH:D000740 Anemia Fluorouracil 3.6115504547 16511603 17963324
MESH:D000799 Angioedema Acetaminophen 3.7410982225
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 3.9619183758
MESH:D001145 Arrhythmias, Cardiac Phenylephrine 4.0117460149
MESH:D001161 Arteriosclerosis Cyclophosphamide 4.4915014928
MESH:D001321 Autistic Disorder Acetaminophen 1.4318445737
MESH:D001778 Blood Coagulation Disorders pirinixic acid 3.0419483382
MESH:D019046 Bone Marrow Neoplasms Doxorubicin 4.5914601052
MESH:D001859 Bone Neoplasms Paclitaxel 4.4615867366
MESH:D001919 Bradycardia Phenylephrine 4.4415306635
MESH:D001932 Brain Neoplasms Doxorubicin 3.7117150277
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 5.7320146248 17474063
MESH:D001943 Breast Neoplasms Cyclophosphamide 5.7315093573 15136595 18323546 17020986 17388661 16978400 12006526 11325840 18234424
MESH:D001943 Breast Neoplasms decitabine 5.7318320071 19208741
MESH:D001943 Breast Neoplasms Diethylnitrosamine 5.7317474063
MESH:D001943 Breast Neoplasms Doxorubicin 5.7316115903 16826403 17369602 15634643 17983394 18234424 15668708 16595493 11325840 17426702 16096432 15994142 18628466 16935488 19526202 18695136 15136595 15567936 15692762 15993339 16264153 18382427 15939500 16322301
MESH:D001943 Breast Neoplasms Estradiol 5.7312948864 19861407 17261762 16675129 14630087 17289903 17018787 18497071
MESH:D001943 Breast Neoplasms Fluorouracil 5.7316110121 15136595 19217205 18608205 16595493 18357371 16557594
MESH:D001943 Breast Neoplasms Genistein 5.7316873071 17200150 16541309
MESH:D001943 Breast Neoplasms Paclitaxel 5.7315136595 11325840 16273361 18323546 16244791 16115903 18223236 18234424
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 4.3516111702
MESH:D002276 Carcinoid Tumor Doxorubicin 12.0016051944
MESH:D002276 Carcinoid Tumor Fluorouracil 12.0016051944
MESH:D002277 Carcinoma Fluorouracil 3.4817121937
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 22.6716705839
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 22.673084413
MESH:D006528 Carcinoma, Hepatocellular Aflatoxin B1 22.6721507988 12619106 12907637
MESH:D006528 Carcinoma, Hepatocellular Cyclophosphamide 22.6719701751
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 22.6720214788 18971187 20514400 17162532 10672840 16779866 19208518 19418558 17173139 20512989 16288022 18785209 17761372 20084675 19539802 18665156 17978847 20007298 19171122 19052882 16569478 19335982 17138121 20524982 17055752 10737359 18506893 21159647 19919837 3581430 16935385 20935162 19701751 3084413 16502159 19107877 20101231 19822196 16878318 19519916 20727157 11831363 18056438 17428255 18978308 19383236 16698587 19394651 16328049 18210153 16681979 18393292 18691550 16807293 18788625 18494052 16540662 20432363 16830150
MESH:D006528 Carcinoma, Hepatocellular Doxorubicin 22.6717876044 16023760 16234567 18059187
MESH:D006528 Carcinoma, Hepatocellular Estradiol 22.6716924424
MESH:D006528 Carcinoma, Hepatocellular Fluorouracil 22.6718930000 16799960 17971768 17088986 16332177 17045692
MESH:D006528 Carcinoma, Hepatocellular Genistein 22.6716924424
MESH:D006528 Carcinoma, Hepatocellular Paclitaxel 22.6716313753
MESH:D018827 Carcinoma, Lewis Lung Cyclophosphamide 4.7816152834
MESH:D002292 Carcinoma, Renal Cell marker/mechanism 19221000
MESH:D002292 Carcinoma, Renal Cell Cyclophosphamide 10.6016201981
MESH:D002292 Carcinoma, Renal Cell Doxorubicin 10.6016201981 1485588
MESH:D002292 Carcinoma, Renal Cell Fluorouracil 10.6018695887
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 10.5620419170
MESH:D002294 Carcinoma, Squamous Cell decitabine 10.5619215824
MESH:D002294 Carcinoma, Squamous Cell Doxorubicin 10.566189445
MESH:D002294 Carcinoma, Squamous Cell Fluorouracil 10.5616280240 17066447 16757204 18986760
MESH:D006332 Cardiomegaly Phenylephrine 3.4711754973 16170337 15728586 17287366 11179087 17124262
MESH:D009202 Cardiomyopathies Doxorubicin 3.4617928571 16651473 16278810 17351982 16952015 17382496 17974986 15811867 16612575 18627295 17924179 16731534 17329180 15792986 17007740 17131338 15476868 16242529 16269455 17519947 17308081 15505089 16455267 16109756 16364871
MESH:D002311 Cardiomyopathy, Dilated Doxorubicin 2.9117334414 16243910
MESH:D002318 Cardiovascular Diseases Genistein 3.2316332659
MESH:D002386 Cataract Acetaminophen 2.5210977129
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 15.3820889678
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 15.3812371664
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 15.3817174075 21159647 2727394 7505956
MESH:D002471 Cell Transformation, Neoplastic Estradiol 15.3818566989
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 3.5919052882
MESH:D002779 Cholestasis Cyclosporine 7.4919486331
MESH:D002779 Cholestasis pirinixic acid 7.4919176532
MESH:D003110 Colonic Neoplasms decitabine 5.7617616700
MESH:D003110 Colonic Neoplasms Fluorouracil 5.7617016597 15001691 17169374 18772588 17018589 16510598 16340194 17725105 17172411 17287894
MESH:D003110 Colonic Neoplasms Genistein 5.7617182828
MESH:D015179 Colorectal Neoplasms decitabine 4.7518981723
MESH:D015179 Colorectal Neoplasms Doxorubicin 4.7518259882 18802399
MESH:D015179 Colorectal Neoplasms Fluorouracil 4.7518949393 17695437 18509181 17401013 17594712 16331619 17255274 15148649 14970324 16282729 15289873 16524972 17016601 18802399 17454858 20501625 18383874 18448328 16303861 16391804 17094418 18288408
MESH:D015179 Colorectal Neoplasms Paclitaxel 4.7518802399
MESH:D003490 Cyanosis 2,4-dinitrotoluene 3.9118551238
MESH:D003556 Cystitis Cyclophosphamide 4.8816989017 18372110 17010015 10700343 16651033 12913760 18710439 17979934 12161096 18295254 15276878 16413132 18093676 18433785 10498854 15643279 11948286 18483878 16614059 12388444
MESH:D007644 Darier Disease Fluorouracil 4.6816733453
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.3818249437
MESH:D003921 Diabetes Mellitus, Experimental Cyclophosphamide 3.9711751995 15331540 10990075
MESH:D003922 Diabetes Mellitus, Type 1 Cyclophosphamide 3.1918772604
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 4.4320387270
MESH:D003924 Diabetes Mellitus, Type 2 Genistein 4.4316647724
MESH:D003928 Diabetic Nephropathies Estradiol 3.3219279558
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 8.7221346803 18551238
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 8.7212705907 19370779 10915739 11461765 17906064 14986274 11529661 11421492 11287661 16177239 14550746 16393943 19739265 18071297 12540782 16109766 11739529 14725611 19923254 16227642 2444490 19085960 11743745 16081117 18713872 17522070 19420014 15968718 12392966 19416960 19164858 16781746 12594235 17562736 10663392 12958197 15619225 11834606 12153990 16485898 10774834
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 8.7219107877
MESH:D056486 Drug-Induced Liver Injury Doxorubicin 8.7217416283
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 3.9919426721
MESH:D004362 Drug Toxicity Doxorubicin 3.5918602426
MESH:D004487 Edema pirinixic acid 2.3812083418
MESH:D004701 Endocrine Gland Neoplasms decitabine 5.0119294695
MESH:D004714 Endometrial Hyperplasia Genistein 4.4816402032
MESH:D016889 Endometrial Neoplasms Doxorubicin 12.1017359293
MESH:D016889 Endometrial Neoplasms Estradiol 12.1019148513 11473722 18566989
MESH:D016889 Endometrial Neoplasms Genistein 12.1011473722
MESH:D004719 Endomyocardial Fibrosis Doxorubicin 5.0518037988
MESH:D004802 Eosinophilia Cyclophosphamide 4.1111006010
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 5.0116302075
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 13.5420426865
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 13.5416530937
MESH:D004938 Esophageal Neoplasms Fluorouracil 13.5416785472 16481741 16337965 17638652 15173087
MESH:D004938 Esophageal Neoplasms nitrosobenzylmethylamine 13.5415547733 15878914 15264214 16704527 15547721 16805852 16510608 15150132 15623463
MESH:D004938 Esophageal Neoplasms Paclitaxel 13.5416481741
MESH:D005234 Fatty Liver Cyclosporine 12.4619224547
MESH:D005234 Fatty Liver Diethylnitrosamine 12.4620387270 21071580
MESH:D005234 Fatty Liver pirinixic acid 12.4620131406 19236843
MESH:D018222 Fibromatosis, Aggressive Doxorubicin 4.4819069698
MESH:D005355 Fibrosis Cyclosporine 3.0312639820 12168785
MESH:D005756 Gastritis Acetaminophen 3.5716983495
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.118708960
MESH:D005909 Glioblastoma Doxorubicin 7.1017150277
MESH:D005909 Glioblastoma Genistein 7.1016598420
MESH:D005910 Glioma Fluorouracil 2.8316145905
MESH:D018316 Gliosarcoma Cyclophosphamide 5.4011389073
MESH:D006086 Graft vs Host Disease Cyclophosphamide 4.9315172196 11014644 16376943
MESH:D006258 Head and Neck Neoplasms decitabine 12.5919215824
MESH:D006258 Head and Neck Neoplasms Doxorubicin 12.5915692506
MESH:D006258 Head and Neck Neoplasms Fluorouracil 12.5915162350 18337622 15102660
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 2.6020471113
MESH:D006331 Heart Diseases Doxorubicin 3.4117875725 18674790 16244372 16707910 16144979 16330681 14766674 18006777 17888722 16244371 16495754 16879835 12587719
MESH:D006333 Heart Failure Doxorubicin 6.8317481944
MESH:D006333 Heart Failure pirinixic acid 6.8320558911
MESH:D006394 Hemangiosarcoma Doxorubicin 3.8015692506
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.3115720958
MESH:D006467 Hemophilia A Cyclophosphamide 5.1811918545
MESH:D006504 Hepatic Veno-Occlusive Disease Cyclophosphamide 5.4314986274
MESH:D006529 Hepatomegaly pirinixic acid 2.8918467677 16221962 19176532 19772884
MESH:D006558 Herpes Genitalis Estradiol 4.9315709030
MESH:D006689 Hodgkin Disease Cyclophosphamide 7.4016135485 17606976
MESH:D006689 Hodgkin Disease Doxorubicin 7.4018501091 17606976 15147373
MESH:D019584 Hot Flashes Estradiol 3.6517088409
MESH:D006930 Hyperalgesia Acetaminophen 2.6116870215
MESH:D006943 Hyperglycemia pirinixic acid 3.0820558911
MESH:D006973 Hypertension Cyclosporine 5.2410903974
MESH:D006973 Hypertension Phenylephrine 5.2412717712 8949925
MESH:D006984 Hypertrophy Phenylephrine 4.4518502941 12791704
MESH:D007154 Immune System Diseases Cyclophosphamide 5.2316076520
MESH:D007248 Infertility, Male Cyclophosphamide 6.897193160 16517039
MESH:D007248 Infertility, Male decitabine 6.8917581917
MESH:D007249 Inflammation Diethylnitrosamine 2.3218785209
MESH:D007333 Insulin Resistance Estradiol 6.9616393666 16627594
MESH:D007333 Insulin Resistance pirinixic acid 6.9616306350
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.3415604871
MESH:D007674 Kidney Diseases Acetaminophen 13.9112587719 15629191
MESH:D007674 Kidney Diseases Cyclosporine 13.9118776723 10903974 8314463
MESH:D007674 Kidney Diseases Doxorubicin 13.9115699352 15369732 16775033
MESH:D007674 Kidney Diseases Estradiol 13.9115618244
MESH:D007676 Kidney Failure, Chronic Doxorubicin 4.0516707910
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 17.0016705839
MESH:D007680 Kidney Neoplasms Cyclosporine 17.0012371664
MESH:D007680 Kidney Neoplasms Estradiol 17.0015610895
MESH:D007680 Kidney Neoplasms Fluorouracil 17.0016985049
MESH:D007938 Leukemia Cyclophosphamide 10.3110602166
MESH:D007938 Leukemia decitabine 10.3119235587 18980019
MESH:D007938 Leukemia Genistein 10.3118980019 17468513
MESH:D004915 Leukemia, Erythroblastic, Acute Doxorubicin 5.0516085563
MESH:D015451 Leukemia, Lymphocytic, Chronic, B-Cell Cyclophosphamide 3.4517658394 18587576 17008537 17296974 18172266 17802794
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive Cyclophosphamide 4.0010373061
MESH:D007951 Leukemia, Myeloid decitabine 3.9018454857 19117987 17236224
MESH:D015470 Leukemia, Myeloid, Acute decitabine 2.3619387464 19010910 18206229 18704418 18460780 17679729
MESH:D015477 Leukemia, Myelomonocytic, Chronic decitabine 5.3618055864
MESH:D007970 Leukopenia Cyclophosphamide 4.8611830472 10052129
MESH:D008080 Liposarcoma Paclitaxel 4.7217353645
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 2.7620032147 18407596 18665156 19638242 18522880
MESH:D008106 Liver Cirrhosis, Experimental Doxorubicin 4.8716439617 16595196
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 4.8714659978 14716833
MESH:D008106 Liver Cirrhosis, Experimental Genistein 4.8717823541
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 4.8715474484
MESH:D008107 Liver Diseases Acetaminophen 3.8116610002 19014921 11587558 12969438 12587719 19784758 16611625 19460945
MESH:D008107 Liver Diseases Diethylnitrosamine 3.8117034775
MESH:D017114 Liver Failure, Acute Acetaminophen 3.1416871587 17185352
MESH:D008113 Liver Neoplasms Aflatoxin B1 17.452125692 9163691 18177683 15890375
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 17.4520195826 21137059
MESH:D008113 Liver Neoplasms beta-Naphthoflavone 17.4519389873 21295105
MESH:D008113 Liver Neoplasms Diethylnitrosamine 17.4519254457 2422723 12771043 18644402 20137499 21047994 15175105 19850985 18648771 19833225 12112319 20434301 19690152 19256749 21278145 19551842 20101389 20492335 19426721 19090486 18977376 19427195 19638242 20405173 19499222 16942905 20583210 18754104 2862719 20501860 19642983 19073162 19255062 9163691 15885732 19812893 19996281 18978307 19294768 10737359 21071580 20452335 21167192 20118626
MESH:D008113 Liver Neoplasms Fluorouracil 17.4518383874 16603448 17045692 15113037
MESH:D008113 Liver Neoplasms pirinixic acid 17.4516377806 20007298 15890375
MESH:D008114 Liver Neoplasms, Experimental Aflatoxin B1 13.628603461
MESH:D008114 Liver Neoplasms, Experimental beta-Naphthoflavone 13.6218164116
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 13.6218308698 18544905 19519916 18775883 16267830 17174075 19004024 17942915 18282651 21159647 16842330 18164116 19009564 18093689 9362446 3124819 19539802 2563599 17854601 18253720 19126423 18079962
MESH:D008114 Liver Neoplasms, Experimental Doxorubicin 13.6217085340 16842330
MESH:D008175 Lung Neoplasms Aflatoxin B1 6.4614755239
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 6.4620464547 20869020 18569708 18520028 18816296 20135361 6695378 20064080 17053015
MESH:D008175 Lung Neoplasms Diethylnitrosamine 6.4620970405 21163286 6695378 20512841
MESH:D008175 Lung Neoplasms Doxorubicin 6.4617418594 6189445
MESH:D008175 Lung Neoplasms Fluorouracil 6.4615246190
MESH:D008178 Lupus Erythematosus, Cutaneous Fluorouracil 4.6815086387
MESH:D008223 Lymphoma Cyclophosphamide 12.2312854902
MESH:D008223 Lymphoma decitabine 12.2319470736
MESH:D008223 Lymphoma Doxorubicin 12.2316098063
MESH:D016393 Lymphoma, B-Cell Cyclophosphamide 4.4916675587
MESH:D008228 Lymphoma, Non-Hodgkin Cyclophosphamide 14.1511911406
MESH:D008228 Lymphoma, Non-Hodgkin Doxorubicin 14.1517654614
MESH:D008228 Lymphoma, Non-Hodgkin Paclitaxel 14.1514749477
MESH:D016399 Lymphoma, T-Cell Doxorubicin 4.4615621674
MESH:D008325 Mammary Neoplasms, Experimental Doxorubicin 9.6315458769
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 9.6311807958 16891317 17203775 11408345
MESH:D008325 Mammary Neoplasms, Experimental Genistein 9.6312929590 14578162
MESH:D020149 Manganese Poisoning Estradiol 4.3819453300
MESH:D008545 Melanoma decitabine 5.1517785578 16505122
MESH:D008545 Melanoma Doxorubicin 5.1516827129
MESH:D008545 Melanoma Paclitaxel 5.1512040289 12025231 16342250
MESH:D008546 Melanoma, Experimental Acetaminophen 10.4719513568
MESH:D008546 Melanoma, Experimental Cyclophosphamide 10.4716388313
MESH:D008654 Mesothelioma Doxorubicin 3.0217638057
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.6816801185
MESH:D028361 Mitochondrial Diseases Doxorubicin 4.4015792986
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 8.2516381670
MESH:D009062 Mouth Neoplasms Fluorouracil 8.2516757204 18986760
MESH:D052016 Mucositis Doxorubicin 4.6817415656
MESH:D009101 Multiple Myeloma decitabine 7.3318172295
MESH:D009101 Multiple Myeloma Paclitaxel 7.3314749477
MESH:D009135 Muscular Diseases pirinixic acid 3.4016239165
MESH:D009190 Myelodysplastic Syndromes decitabine 3.3216882708 19157545 18608210 19010910
MESH:D009203 Myocardial Infarction Doxorubicin 9.2219429709 15857846
MESH:D009203 Myocardial Infarction Genistein 9.2217141266
MESH:D009203 Myocardial Infarction pirinixic acid 9.2219151258
MESH:D015428 Myocardial Reperfusion Injury Estradiol 13.6816810080
MESH:D015428 Myocardial Reperfusion Injury Genistein 13.6817141266
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 13.6816411023
MESH:D009336 Necrosis 2,4-dinitrotoluene 3.7518551238
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 9.379029167 3581430
MESH:D009362 Neoplasm Metastasis Doxorubicin 9.3718259882
MESH:D009362 Neoplasm Metastasis Paclitaxel 9.3715867366
MESH:D009369 Neoplasms Benzo(a)pyrene 15.1711141357
MESH:D009369 Neoplasms Cyclophosphamide 15.1718854779
MESH:D009369 Neoplasms decitabine 15.1717925555 19470736 19116145
MESH:D009369 Neoplasms Fluorouracil 15.1718600527 18239605 16928823
MESH:D009369 Neoplasms pirinixic acid 15.1717405874
MESH:D009389 Neovascularization, Pathologic Estradiol 3.6217289903
MESH:D009401 Nephrosis Doxorubicin 4.6616899518 16636307
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.3417954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 8.9818481113 19348381
MESH:D009404 Nephrotic Syndrome Doxorubicin 8.9816889571 15640375
MESH:D009421 Nervous System Malformations Estradiol 9.4116427766 11399458
MESH:D009421 Nervous System Malformations Genistein 9.4116427766
MESH:D009447 Neuroblastoma Cyclophosphamide 7.0315176712 8761367 16115947
MESH:D009447 Neuroblastoma Doxorubicin 7.0315555623
MESH:D019636 Neurodegenerative Diseases Acetaminophen 7.8818514411
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 7.8820387270
MESH:D017599 Neuroectodermal Tumors Cyclophosphamide 4.7812837982 8761367
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 5.0120387270
MESH:D020258 Neurotoxicity Syndromes Fluorouracil 3.3616436463
MESH:D009503 Neutropenia Cyclophosphamide 4.228291058
MESH:D009765 Obesity pirinixic acid 1.7920558911
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 3.3316049721 12819281
MESH:D009845 Oligospermia Cyclophosphamide 4.6016517039
MESH:D010014 Osteolysis Paclitaxel 4.8715867366
MESH:D010024 Osteoporosis Genistein 3.1819401787
MESH:D015663 Osteoporosis, Postmenopausal Genistein 3.9816169203
MESH:D012516 Osteosarcoma Doxorubicin 4.0215930896
MESH:D010051 Ovarian Neoplasms decitabine 11.0619259094 19331143
MESH:D010051 Ovarian Neoplasms Estradiol 11.0619401270
MESH:D010051 Ovarian Neoplasms Genistein 11.0619005980
MESH:D010051 Ovarian Neoplasms Paclitaxel 11.0611161223
MESH:D010146 Pain Acetaminophen 6.5516870215
MESH:D010146 Pain Cyclophosphamide 6.5518093676 12161096
MESH:D010190 Pancreatic Neoplasms Cyclophosphamide 12.0611332152
MESH:D010190 Pancreatic Neoplasms decitabine 12.0619294695
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 12.0616540662
MESH:D010190 Pancreatic Neoplasms Fluorouracil 12.0615113037 16929163 19003803 16500647
MESH:D003557 Phyllodes Tumor Doxorubicin 5.0517983394
MESH:D010997 Pleural Neoplasms Doxorubicin 5.0517638057
MESH:D011230 Precancerous Conditions Cyclosporine 8.6312371664
MESH:D011230 Precancerous Conditions Diethylnitrosamine 8.632563599
MESH:D054198 Precursor Cell Lymphoblastic Leukemia-Lymphoma Cyclophosphamide 3.7421297632
MESH:D055728 Primary Myelofibrosis decitabine 4.6217616702
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 3.7820887781
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 2.4417292933
MESH:D011471 Prostatic Neoplasms Cyclophosphamide 2.4417136230
MESH:D011471 Prostatic Neoplasms Doxorubicin 2.4415749863 16729912 16868541 15897917 16888761 18437689
MESH:D011471 Prostatic Neoplasms Estradiol 2.4416740699
MESH:D011471 Prostatic Neoplasms Fluorouracil 2.4419082440 18626508
MESH:D011471 Prostatic Neoplasms Genistein 2.4415256057 15378649 16925846
MESH:D011471 Prostatic Neoplasms methylselenic acid 2.4416205645
MESH:D011471 Prostatic Neoplasms Paclitaxel 2.4417136230 16356831 16729912 17172428
MESH:D011565 Psoriasis Cyclosporine 2.1916882103
MESH:D011658 Pulmonary Fibrosis Cyclophosphamide 3.2416636934
MESH:D012004 Rectal Neoplasms Fluorouracil 3.9216160472 15538739 18722050 18286688
MESH:D051437 Renal Insufficiency Doxorubicin 4.1117922066
MESH:D015427 Reperfusion Injury pirinixic acid 2.3319058328
MESH:D012208 Rhabdomyosarcoma decitabine 4.3019155313
MESH:D012509 Sarcoma Doxorubicin 3.8917710206 17203757 18313854 16767912 15625365 15675481
MESH:D012512 Sarcoma, Ewing's Doxorubicin 4.1316326096 14601052
MESH:D012514 Sarcoma, Kaposi Doxorubicin 4.6817846226
MESH:D012595 Scleroderma, Systemic Cyclophosphamide 4.7216636934
MESH:D012640 Seizures 2,4-dinitrotoluene 2.4618551238
MESH:D012852 Sinusitis Phenylephrine 4.597327846
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 5.6419755658 10029692
MESH:D012878 Skin Neoplasms Doxorubicin 5.6415692506
MESH:D012983 Soft Tissue Neoplasms Doxorubicin 4.4617203757 15625365 16767912
OMIM:102530 SPERMATOGENIC FAILURE 6 Cyclophosphamide 5.4016517039
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 8.172093021 20155912
MESH:D013274 Stomach Neoplasms decitabine 8.1719037991
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 8.1718456281
MESH:D013274 Stomach Neoplasms Fluorouracil 8.1716424979 17498489 18396642 17522103 16951190 18567086 19015929 19084572 15786421 17172411
MESH:D013274 Stomach Neoplasms nitrosobenzylmethylamine 8.1717575124 12958204
MESH:D013274 Stomach Neoplasms Paclitaxel 8.1718396642 18506536
MESH:D015173 Supratentorial Neoplasms Cyclophosphamide 4.9512837982
MESH:D024801 Tauopathies Paclitaxel 4.7016930453
MESH:D013964 Thyroid Neoplasms decitabine 11.5717967635
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 11.577505956
MESH:D013964 Thyroid Neoplasms Doxorubicin 11.5716010429 17909728
MESH:D013978 Tibial Fractures Estradiol 4.5819048282
MESH:D014062 Tongue Neoplasms Fluorouracil 3.8916280240
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 15.3716049721
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 15.3717053015
MESH:D001749 Urinary Bladder Neoplasms Cyclophosphamide 15.3714692829
MESH:D001749 Urinary Bladder Neoplasms decitabine 15.3717616700 19087683
MESH:D001749 Urinary Bladder Neoplasms Doxorubicin 15.3717653716
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 4.2110091137
MESH:D014581 Urticaria Acetaminophen 2.8710982225
MESH:D002583 Uterine Cervical Neoplasms Fluorouracil 3.7816803524
MESH:D014604 Uveal Neoplasms decitabine 4.8117785578
MESH:D014605 Uveitis Cyclosporine 3.881336536
MESH:D018487 Ventricular Dysfunction, Left Doxorubicin 4.1117638931 17678736 16364871 17334414
MESH:D014985 Xerophthalmia Cyclosporine 4.3417120751
Pathway ID Pathway Name
KEGG:03018 RNA degradation
Pharmacogenomics Knowledge Base Top
Drug Bank Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved