AutismKB 2.0

Annotation Detail for YWHAQ


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Basic Information Top
Gene Symbol:YWHAQ ( 14-3-3,1C5,HS1 )
Gene Full Name: tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide
Band: 2p25.1
Quick LinksEntrez ID:10971; OMIM: 609009; Uniprot ID:1433T_HUMAN; ENSEMBL ID: ENSG00000134308; HGNC ID: 12854
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa05130Pathogenic Escherichia coli infection
hsa04722Neurotrophin signaling pathway
hsa04110Cell cycle
hsa04114Oocyte meiosis
No data
Pathway IDPathway Name
200076Role of Calcineurin-dependent NFAT signaling in lymphocytes
Pathway IDPathway Name
P00018EGF receptor signaling pathway
P00049Parkinson disease
P00021FGF signaling pathway
No data
Related Diseases/Disorders Top
No data
Desease IDDesease Name
2066Lung cancer
2225Gram-Negative bacterial infection
2244Prion disease
No data
No data
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene affects the expression of YWHAQ mRNAaffects expression 21346803
D000643 Ammonium Chloride Ammonium Chloride affects the expression of YWHAQ mRNAaffects expression 16483693
D001554 Benzene [Benzene co-treated with methylmercury II co-treated with Trichloroethylene] results in increased expression of YWHAQ mRNAaffects cotreatment|increases expression 17905399
C032036 bromobenzene bromobenzene results in decreased expression of YWHAQ mRNAdecreases expression 15056800
D004052 Diethylnitrosamine Diethylnitrosamine results in increased expression of YWHAQ mRNAincreases expression 19638242
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of YWHAQ mRNAaffects cotreatment|increases expression 17942748
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of YWHAQ mRNAincreases expression 17108234
D017313 Fenretinide Fenretinide affects the localization of YWHAQ proteinaffects localization 17110918
D006830 Hydralazine [Hydralazine co-treated with Valproic Acid] results in increased expression of YWHAQ mRNAaffects cotreatment|increases expression 17183730
C030957 methylmercury II [Benzene co-treated with methylmercury II co-treated with Trichloroethylene] results in increased expression of YWHAQ mRNAaffects cotreatment|increases expression 17905399
D017239 Paclitaxel Paclitaxel results in increased expression of YWHAQ proteinincreases expression 10822281
C008776 pelargonic acid pelargonic acid results in increased expression of YWHAQ mRNAincreases expression 11379042
C006253 pirinixic acid pirinixic acid results in decreased expression of YWHAQ mRNAdecreases expression 18445702
C443641 poly(propyleneimine) poly(propyleneimine) analog results in decreased expression of YWHAQ mRNAdecreases expression 16308212
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of YWHAQ mRNAaffects cotreatment|increases expression 17942748
D013852 Thiotepa Thiotepa results in increased expression of YWHAQ proteinincreases expression 10822281
D014051 Toluene 2,4-Diisocyanate Toluene 2,4-Diisocyanate results in increased expression of YWHAQ mRNAincreases expression 11379042
D014241 Trichloroethylene [Benzene co-treated with methylmercury II co-treated with Trichloroethylene] results in increased expression of YWHAQ mRNAaffects cotreatment|increases expression 17905399
D014501 Uranium Uranium affects the expression of YWHAQ mRNAaffects expression 15672453
C005460 uranyl acetate uranyl acetate affects the expression of YWHAQ mRNAaffects expression 15672453
D014635 Valproic Acid [Hydralazine co-treated with Valproic Acid] results in increased expression of YWHAQ mRNAaffects cotreatment|increases expression 17183730
D014747 Vinblastine YWHAQ protein affects the susceptibility to Vinblastineaffects response to substance 16217747
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 7.9514514962 15322242 11752688
MESH:D000014 Abnormalities, Drug-Induced Valproic Acid 7.958875741
MESH:D000015 Abnormalities, Multiple Valproic Acid 3.8319490988
MESH:D000138 Acidosis Ammonium Chloride 3.4518287403
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.8417505938
MESH:D055371 Acute Lung Injury pirinixic acid 3.0118653653
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 4.5014692618
MESH:D000230 Adenocarcinoma Fenretinide 4.5010697514
MESH:D000236 Adenoma Diethylnitrosamine 2.796695378 10737359
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 16.6519061943 16434500 19052882 17620307 17162532 18056438
MESH:D018248 Adenoma, Liver Cell pirinixic acid 16.6516434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 16.6516835633
MESH:D000550 Amblyopia Valproic Acid 5.1317688650
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.8511748828
MESH:D000741 Anemia, Aplastic Benzene 4.2811369114 17661222 14761424
MESH:D001008 Anxiety Disorders Valproic Acid 3.4817497229
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.3611256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 2.6015885639
MESH:D001249 Asthma Toluene 2,4-Diisocyanate 3.476091946 15590891 19187332 17015710 12762349 11077013 12585506 8156442 18394133 6091945 7684630 10797510 11467998 15590890 170078 3040596 20032816 16210060 16792590 15855793 11742282 12684321 10934080
MESH:D001321 Autistic Disorder Valproic Acid 2.0119460635 18316065 18775368 18940202 18177632 18985861 15238991 17688650 16609825 18396377 19232924 17507914 20603192 17157402 18558336
MESH:D001714 Bipolar Disorder Valproic Acid 3.0217594078 20046352
MESH:D001778 Blood Coagulation Disorders pirinixic acid 8.4319483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 8.4312125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.6915340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 7.7915746008
MESH:D001848 Bone Diseases, Developmental Valproic Acid 7.798888407
MESH:D001855 Bone Marrow Diseases Benzene 5.1216183116
MESH:D001859 Bone Neoplasms Paclitaxel 4.4615867366
MESH:D001932 Brain Neoplasms Fenretinide 4.2516187019
MESH:D001943 Breast Neoplasms Benzene 3.7117162533 11921183
MESH:D001943 Breast Neoplasms Diethylnitrosamine 3.7117474063
MESH:D001943 Breast Neoplasms Fenretinide 3.7116601279
MESH:D001943 Breast Neoplasms Paclitaxel 3.7111325840 15136595 18223236 18323546 18234424 16115903 16273361 16244791
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 3.7120435547
MESH:D001943 Breast Neoplasms Toluene 2,4-Diisocyanate 3.7111921183
MESH:D001943 Breast Neoplasms Trichloroethylene 3.7115986119
MESH:D016535 Bronchial Hyperreactivity Toluene 2,4-Diisocyanate 4.458156442 12507178 15590891
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.7116835633
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 6.5116705839
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 6.5110737359 3084413 20214788 18494052 19208518 20101231 16569478 19052882 20727157 18785209 17055752 19539802 16328049 16698587 18665156 20007298 19418558 19383236 16502159 20524982 18971187 19107877 19919837 19519916 20514400 20935162 10672840 18788625 16878318 16540662 16935385 16830150 18210153 16681979 18691550 17138121 18056438 18506893 19335982 21159647 20084675 17428255 3581430 19701751 17761372 18978308 20432363 19171122 11831363 16288022 16779866 20512989 17978847 18393292 17162532 19394651 16807293 17173139 19822196
MESH:D006528 Carcinoma, Hepatocellular Fenretinide 6.5116270382 17159502
MESH:D006528 Carcinoma, Hepatocellular Paclitaxel 6.5116313753
MESH:D002292 Carcinoma, Renal Cell Vinblastine 3.731485588
MESH:D002294 Carcinoma, Squamous Cell Fenretinide 3.1516274795
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.3118850075 16120746 18670907
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 6.446135515
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 6.447505956 21159647 2727394 17174075
MESH:D018290 Cervical Intraepithelial Neoplasia Fenretinide 5.3716154183
MESH:D002659 Child Development Disorders, Pervasive Valproic Acid 2.6720734317
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 9.0119052882
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 9.0116835633
MESH:D002779 Cholestasis Ethinyl Estradiol 7.4711677210 17333356 16105132 17110522 17681005 15861022 16919318
MESH:D002779 Cholestasis pirinixic acid 7.4719176532
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 2.068697196 15340226 16354765 15668235 12621046
MESH:D015179 Colorectal Neoplasms Fenretinide 3.6817273769
MESH:D015179 Colorectal Neoplasms Paclitaxel 3.6818802399
MESH:D015179 Colorectal Neoplasms Vinblastine 3.6818802399
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 2.9617141729 14669216
MESH:D019465 Craniofacial Abnormalities Benzene 3.7815643154
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 3.7815322242 20055451 10048152
MESH:D019465 Craniofacial Abnormalities Valproic Acid 3.7816575769 8888407 17688650
MESH:D003490 Cyanosis 2,6-dinitrotoluene 3.9118551238
MESH:D003872 Dermatitis Benzene 4.6615902427
MESH:D017449 Dermatitis, Allergic Contact Toluene 2,4-Diisocyanate 4.0015491423 18759878 12956900
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.3818249437
MESH:D003877 Dermatitis, Contact Toluene 2,4-Diisocyanate 4.6817010967
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 4.1320387270
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 4.1317107852
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 14.8621346803 18551238
MESH:D056486 Drug-Induced Liver Injury bromobenzene 14.8610092053 12628495
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 14.8619107877
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 14.8620420201
MESH:D056486 Drug-Induced Liver Injury Trichloroethylene 14.867120509
MESH:D056486 Drug-Induced Liver Injury Valproic Acid 14.8619641884 1733752
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.6811462148
MESH:D004421 Dystonia Valproic Acid 3.941851702
MESH:D004487 Edema pirinixic acid 6.2012083418
MESH:D004487 Edema Tetrachlorodibenzodioxin 6.2012711302 11000095
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.8018230668 16714409 15322242
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 3.0812538720
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 2.9210568697 9294722
MESH:D004802 Eosinophilia Toluene 2,4-Diisocyanate 4.548156442
MESH:D004831 Epilepsies, Myoclonic Valproic Acid 4.043659116 17275665
MESH:D004828 Epilepsies, Partial Valproic Acid 3.8116628512 3922381
MESH:D004827 Epilepsy Valproic Acid 2.8820417680 18234410
MESH:D004832 Epilepsy, Absence Valproic Acid 3.496426943 6254150 7562514
MESH:D017029 Epilepsy, Complex Partial Valproic Acid 4.197750514
MESH:D004830 Epilepsy, Tonic-Clonic Valproic Acid 3.963659116
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 5.0116302075
MESH:D004938 Esophageal Neoplasms Paclitaxel 2.8716481741
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 2.9311564622
MESH:D005128 Eye Diseases Toluene 2,4-Diisocyanate 5.6418447907
MESH:D005234 Fatty Liver Diethylnitrosamine 17.9220387270 21071580
MESH:D005234 Fatty Liver Ethinyl Estradiol 17.9215345470
MESH:D005234 Fatty Liver pirinixic acid 17.9219236843 20131406
MESH:D005234 Fatty Liver Valproic Acid 17.9214986274 19224547
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.3511858732
MESH:D005315 Fetal Diseases Valproic Acid 4.7816575769
MESH:D005317 Fetal Growth Retardation Valproic Acid 4.0218558336 8888407
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 2.8420067830
MESH:D005909 Glioblastoma Fenretinide 3.8216187019
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.4910696789
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 2.2710048152 11294989
MESH:D006333 Heart Failure pirinixic acid 2.4720558911
MESH:D006402 Hematologic Diseases Benzene 4.5516183116
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.2311000095
MESH:D006529 Hepatomegaly pirinixic acid 7.9019176532 18467677 19772884 16221962
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 7.9016120746 15340226 12621046
MESH:D006689 Hodgkin Disease Vinblastine 3.9418501091 18180244
MESH:D006849 Hydrocephalus Valproic Acid 4.7617688650
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.9418606429 8697196 15340226 16354765 16959395
MESH:D006943 Hyperglycemia pirinixic acid 3.0820558911
MESH:D006967 Hypersensitivity Toluene 2,4-Diisocyanate 4.5011019492 10880147
MESH:D006973 Hypertension Benzene 5.1717940673
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 5.1718670907 18850075
MESH:D046110 Hypertension, Pregnancy-Induced Hydralazine 4.5216612254
MESH:D007021 Hypospadias Ethinyl Estradiol 3.7016945680 16569931
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.3612013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 2.4117937319
MESH:D007249 Inflammation Diethylnitrosamine 4.7118785209
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 4.7112878042 12200463
MESH:D007333 Insulin Resistance pirinixic acid 2.5616306350
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 3.2316580747
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 2.8916705839
MESH:D007938 Leukemia Benzene 3.3418335105 17119257 15935818 14694614
MESH:D007945 Leukemia, Lymphoid Thiotepa 6.1710069464
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive Thiotepa 5.1210373061
MESH:D007951 Leukemia, Myeloid Benzene 10.0217506065
MESH:D007951 Leukemia, Myeloid Thiotepa 10.0210069464
MESH:D015470 Leukemia, Myeloid, Acute Benzene 4.0519478238
MESH:D015470 Leukemia, Myeloid, Acute Valproic Acid 4.0516294345 17596541
MESH:D007972 Leukoplakia, Oral Fenretinide 5.9416707609
MESH:D008080 Liposarcoma Paclitaxel 4.7217353645
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 2.7618407596 19638242 18665156 20032147 18522880
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 2.1015474484
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 2.1012878042
MESH:D008107 Liver Diseases Diethylnitrosamine 2.0717034775
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 10.327678174
MESH:D008113 Liver Neoplasms Diethylnitrosamine 10.3219642983 19812893 19254457 20118626 2422723 18978307 15175105 16942905 2862719 19256749 18977376 19426721 19090486 19427195 21071580 9163691 20501860 15885732 19551842 19833225 20101389 20452335 19294768 10737359 18648771 19499222 19996281 20434301 19850985 20492335 20137499 18644402 20405173 19073162 12771043 12112319 19255062 19690152 21278145 20583210 21047994 18754104 19638242 21167192
MESH:D008113 Liver Neoplasms pirinixic acid 10.3216377806 15890375 20007298
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 10.3216984957
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 17.952876784 2876786 6135515
MESH:D008114 Liver Neoplasms, Experimental Benzene 17.9512562636
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 17.9516267830 18308698 2563599 18544905 19539802 17174075 19519916 21159647 9362446 19126423 18079962 18093689 19009564 18253720 18282651 18164116 19004024 17854601 3124819 16842330 18775883 17942915
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 17.9512151625
MESH:D008114 Liver Neoplasms, Experimental Trichloroethylene 17.957955063
MESH:D017563 Lung Diseases, Interstitial Benzene 11.0314698565
MESH:D017563 Lung Diseases, Interstitial Valproic Acid 11.0317228818
MESH:D008175 Lung Neoplasms Benzene 3.3912562636
MESH:D008175 Lung Neoplasms Diethylnitrosamine 3.3920512841 20970405 21163286 6695378
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 3.3911884234 19555203
MESH:D008223 Lymphoma Benzene 8.1317119257 17584886
MESH:D008223 Lymphoma Thiotepa 8.1310069464
MESH:D008228 Lymphoma, Non-Hodgkin Paclitaxel 4.0014749477
MESH:D015674 Mammary Neoplasms, Animal Benzene 4.3312562636
MESH:D008325 Mammary Neoplasms, Experimental Benzene 6.3611921183
MESH:D008325 Mammary Neoplasms, Experimental Fenretinide 6.3610697514
MESH:D008545 Melanoma Fenretinide 5.3216270382
MESH:D008545 Melanoma Paclitaxel 5.3212025231 16342250 12040289
MESH:D008545 Melanoma Vinblastine 5.3218505091 12374674 18176117 15577320 16248763 16432458 16809738 17761969 18332650 15577323
MESH:D008881 Migraine Disorders Valproic Acid 3.1118803445 18765137
MESH:D009062 Mouth Neoplasms Fenretinide 4.2316274795
MESH:D009101 Multiple Myeloma Benzene 7.4517119195
MESH:D009101 Multiple Myeloma Paclitaxel 7.4514749477
MESH:D009135 Muscular Diseases pirinixic acid 3.4016239165
MESH:D009139 Musculoskeletal Abnormalities Valproic Acid 3.928888407
MESH:D009190 Myelodysplastic Syndromes Valproic Acid 3.0917596541
MESH:D009203 Myocardial Infarction pirinixic acid 2.1019151258
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 2.9312213967
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 2.8616411023
MESH:D009336 Necrosis 2,6-dinitrotoluene 3.7518551238 7678174
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 5.859029167 3581430
MESH:D009362 Neoplasm Metastasis Paclitaxel 5.8515867366
MESH:D009369 Neoplasms Fenretinide 11.6017353921 15958647
MESH:D009369 Neoplasms pirinixic acid 11.6017405874
MESH:D009369 Neoplasms Thiotepa 11.6018854779
MESH:D009369 Neoplasms Trichloroethylene 11.6011911487
MESH:D009374 Neoplasms, Experimental Toluene 2,4-Diisocyanate 4.621670384
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 3.1114600291
MESH:D009436 Neural Tube Defects Benzene 7.3015643154
MESH:D009436 Neural Tube Defects Valproic Acid 7.308888407 16359493
MESH:D009447 Neuroblastoma Thiotepa 4.708761367
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 3.2520387270
MESH:D017599 Neuroectodermal Tumors Thiotepa 5.9012837982 8761367
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 5.0120387270
MESH:D009472 Neuronal Ceroid-Lipofuscinoses Fenretinide 5.5716303764
MESH:D009503 Neutropenia Vinblastine 4.4717378895
MESH:D009765 Obesity pirinixic acid 1.7920558911
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 14.7716049721
MESH:D009784 Occupational Diseases Benzene 14.7715913788 15727169 15576619 15612468 16737584 15935809 17119257 17178637 17479406
MESH:D009784 Occupational Diseases Toluene 2,4-Diisocyanate 14.778156442 6091946 18394133 3040596 6091945 12585506 11077013
MESH:D010014 Osteolysis Paclitaxel 4.8715867366
MESH:D010051 Ovarian Neoplasms Benzene 7.9712562636
MESH:D010051 Ovarian Neoplasms Fenretinide 7.9716133793
MESH:D010051 Ovarian Neoplasms Paclitaxel 7.9711161223
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 5.4516540662
MESH:D010190 Pancreatic Neoplasms Fenretinide 5.4515580305
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.5811578682
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.1412520081
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.4518163543
MESH:D011230 Precancerous Conditions Diethylnitrosamine 3.462563599
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 9.1011222880 11896295 11399792 11118676
MESH:D011297 Prenatal Exposure Delayed Effects Valproic Acid 9.1020603192
MESH:D011471 Prostatic Neoplasms Fenretinide 3.8417024972
MESH:D011471 Prostatic Neoplasms Paclitaxel 3.8417136230 17172428 16729912 16356831
MESH:D011537 Pruritus Ethinyl Estradiol 3.2015861022 16919318
MESH:D019310 Pseudolymphoma Valproic Acid 4.4412752131 11422049
MESH:D011657 Pulmonary Eosinophilia Toluene 2,4-Diisocyanate 5.5214606601
MESH:D015427 Reperfusion Injury pirinixic acid 2.3319058328
MESH:D012130 Respiratory Hypersensitivity Toluene 2,4-Diisocyanate 4.3616940033 7692837 20219652
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.7318990726
MESH:D012140 Respiratory Tract Diseases Toluene 2,4-Diisocyanate 5.0118447907
MESH:D012162 Retinal Degeneration Fenretinide 4.3216303925
MESH:D012208 Rhabdomyosarcoma Valproic Acid 4.0719155313
MESH:D012220 Rhinitis Toluene 2,4-Diisocyanate 4.4819050374
MESH:D012221 Rhinitis, Allergic, Perennial Toluene 2,4-Diisocyanate 5.1712617775 15015336
MESH:D006255 Rhinitis, Allergic, Seasonal Toluene 2,4-Diisocyanate 5.4119075512
MESH:D012559 Schizophrenia Valproic Acid 2.0519110320 15737665
MESH:D012640 Seizures 2,6-dinitrotoluene 5.6918551238
MESH:D012640 Seizures Valproic Acid 5.691511512 16876388 11044598 14763951 11738929 17978042 3137016 15475178
MESH:D012878 Skin Neoplasms Fenretinide 5.7216467112
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 5.7216192470
MESH:D012912 Sneezing Toluene 2,4-Diisocyanate 5.4119075512 19050374
MESH:D013088 Spermatocele Ethinyl Estradiol 3.8416709447
MESH:D016135 Spinal Dysraphism Valproic Acid 3.6919490988
MESH:D013226 Status Epilepticus Valproic Acid 4.4412833885
MESH:D013274 Stomach Neoplasms Benzene 3.4712562636
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 3.4718456281
MESH:D013274 Stomach Neoplasms Paclitaxel 3.4718506536 18396642
MESH:D015173 Supratentorial Neoplasms Thiotepa 6.0612837982
MESH:D024801 Tauopathies Paclitaxel 4.7016930453
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.5211994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.0615669648
MESH:D013953 Thymus Neoplasms Benzene 4.8510850423
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.8012697716
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 2.907505956
MESH:D014178 Translocation, Genetic Valproic Acid 5.1317262798
MESH:D020194 Unverricht-Lundborg Syndrome Valproic Acid 4.413119515
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 5.2416049721
MESH:D001749 Urinary Bladder Neoplasms Fenretinide 5.2416720286
MESH:D014564 Urogenital Abnormalities Valproic Acid 4.538888407
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 4.2110091137
MESH:D002583 Uterine Cervical Neoplasms Fenretinide 4.4616154183
MESH:D014594 Uterine Neoplasms Benzene 9.2112562636
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 9.2114692618
MESH:D014625 Vaginal Neoplasms Vinblastine 4.9415577323
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.4912125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.4415869587 14671159
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.1415886252
Pathway ID Pathway Name
KEGG:04110 Cell cycle
KEGG:04722 Neurotrophin signaling pathway
KEGG:04114 Oocyte meiosis
KEGG:05130 Pathogenic Escherichia coli infection
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA37443
    • No data
    No data
    Releated drug ID Related drug Name
    PA451578tacrolimus
    Drug Bank Top

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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