Annotation Detail for FERMT2
Basic Information
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| Gene Symbol: | FERMT2 ( DKFZp686G11125,FLJ34213,FLJ44462,KIND2,MIG2,PLEKHC1,UNC112,UNC112B,mig-2 ) |
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| Gene Full Name: | fermitin family member 2 |
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| Band: | 14q22.1 |
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| Quick Links | Entrez ID:10979; OMIM: 607746; Uniprot ID:FERM2_HUMAN; ENSEMBL ID: ENSG00000073712; HGNC ID: 15767 |
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| Relate to Another Database: |
SFARIGene;
denovo-db |
| Pathway ID | Pathway Name |
|---|
| Cell junction organization |
| Pathway ID | Pathway Name |
|---|
| 500123 | Cell-extracellular matrix interactions |
| Desease ID | Desease Name |
|---|
| 1864 | Fibroid tumor |
| Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
|---|
| D001564 |
Benzo(a)pyrene |
Benzo(a)pyrene results in decreased expression of FERMT2 mRNA | decreases expression | 20106945
|
| D015123 |
7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide |
7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of FERMT2 mRNA | decreases expression | 20018196
|
| C006253 |
pirinixic acid |
[pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of FERMT2 mRNA | affects binding|decreases expression|increases activity | 19710929
|
| Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
|---|
| MESH:D055371 |
Acute Lung Injury |
|
pirinixic acid |
3.64 | 18653653 |
| MESH:D000230 |
Adenocarcinoma |
|
Benzo(a)pyrene |
2.06 | 20127859 20464547 |
| MESH:D000236 |
Adenoma |
|
Benzo(a)pyrene |
2.88 | 6695378 |
| MESH:D018248 |
Adenoma, Liver Cell |
|
pirinixic acid |
4.22 | 16434500 |
| MESH:D017544 |
Aortic Aneurysm, Abdominal |
|
Benzo(a)pyrene |
4.73 | 19183758 |
| MESH:D001778 |
Blood Coagulation Disorders |
|
pirinixic acid |
3.63 | 19483382 |
| MESH:D001943 |
Breast Neoplasms |
|
Benzo(a)pyrene |
1.99 | 20146248 17474063 |
| MESH:D002294 |
Carcinoma, Squamous Cell |
|
Benzo(a)pyrene |
2.14 | 20419170 |
| MESH:D002471 |
Cell Transformation, Neoplastic |
|
7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide |
3.01 | 20889678 |
| MESH:D002779 |
Cholestasis |
|
pirinixic acid |
3.15 | 19176532 |
| MESH:D003876 |
Dermatitis, Atopic |
|
pirinixic acid |
2.59 | 18249437 |
| MESH:D004487 |
Edema |
|
pirinixic acid |
2.96 | 12083418 |
| MESH:D004938 |
Esophageal Neoplasms |
|
7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide |
4.64 | 20426865 |
| MESH:D004938 |
Esophageal Neoplasms |
|
Benzo(a)pyrene |
4.64 | 16530937 |
| MESH:D005234 |
Fatty Liver |
|
pirinixic acid |
3.25 | 20131406 19236843 |
| MESH:D006330 |
Heart Defects, Congenital |
|
Benzo(a)pyrene |
2.85 | 20471113 |
| MESH:D006333 |
Heart Failure |
|
pirinixic acid |
2.78 | 20558911 |
| MESH:D006529 |
Hepatomegaly |
|
pirinixic acid |
3.64 | 18467677 16221962 19176532 19772884 |
| MESH:D006943 |
Hyperglycemia |
|
pirinixic acid |
3.63 | 20558911 |
| MESH:D007333 |
Insulin Resistance |
|
pirinixic acid |
2.90 | 16306350 |
| MESH:D008106 |
Liver Cirrhosis, Experimental |
|
pirinixic acid |
1.35 | 15474484 |
| MESH:D008113 |
Liver Neoplasms |
|
Benzo(a)pyrene |
4.81 | 21137059 20195826 |
| MESH:D008113 |
Liver Neoplasms |
|
pirinixic acid |
4.81 | 20007298 16377806 15890375 |
| MESH:D008175 |
Lung Neoplasms |
|
Benzo(a)pyrene |
1.57 | 18569708 20464547 18816296 17053015 20064080 18520028 20869020 6695378 20135361 |
| MESH:D009062 |
Mouth Neoplasms |
|
Benzo(a)pyrene |
3.53 | 16381670 |
| MESH:D009135 |
Muscular Diseases |
|
pirinixic acid |
4.16 | 16239165 |
| MESH:D009203 |
Myocardial Infarction |
|
pirinixic acid |
2.29 | 19151258 |
| MESH:D015428 |
Myocardial Reperfusion Injury |
|
pirinixic acid |
3.29 | 16411023 |
| MESH:D009369 |
Neoplasms |
|
Benzo(a)pyrene |
5.44 | 11141357 |
| MESH:D009369 |
Neoplasms |
|
pirinixic acid |
5.44 | 17405874 |
| MESH:D009765 |
Obesity |
|
pirinixic acid |
1.89 | 20558911 |
| MESH:D011471 |
Prostatic Neoplasms |
|
Benzo(a)pyrene |
2.90 | 17292933 |
| MESH:D015427 |
Reperfusion Injury |
|
pirinixic acid |
2.56 | 19058328 |
| MESH:D012878 |
Skin Neoplasms |
|
Benzo(a)pyrene |
2.54 | 10029692 19755658 |
| MESH:D013274 |
Stomach Neoplasms |
|
Benzo(a)pyrene |
1.56 | 20155912 2093021 |
| MESH:D001749 |
Urinary Bladder Neoplasms |
|
Benzo(a)pyrene |
2.31 | 17053015 |
| Pathway ID |
Pathway Name |
|---|
| REACT:20676 |
Cell junction organization |
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