Gene Symbol:	ILVBL ( 209L8,AHAS,ILV2H,MGC1269,MGC19535 )
Gene Full Name:	ilvB (bacterial acetolactate synthase)-like
Band:	19p13.12
Quick Links	Entrez ID:10994; OMIM: 605770; Uniprot ID:ILVBL_HUMAN; ENSEMBL ID: ENSG00000105135; HGNC ID: 6041
Relate to Another Database:	SFARIGene; denovo-db

Chemical ID	Chemical Name	Interaction	Interaction Action	Publication
D000082	Acetaminophen	Acetaminophen affects the expression of ILVBL mRNA	affects expression	17562736
D016718	Arachidonic Acid	Arachidonic Acid results in decreased expression of ILVBL mRNA	decreases expression	16704987
D020122	tert-Butylhydroperoxide	tert-Butylhydroperoxide results in decreased expression of ILVBL mRNA	decreases expression	15336504
D010634	Phenobarbital	Phenobarbital results in increased expression of ILVBL mRNA	increases expression	19270015
C006253	pirinixic acid	[pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of ILVBL mRNA	affects binding\|increases activity\|increases expression	19710929
C006253	pirinixic acid	pirinixic acid results in increased expression of ILVBL mRNA	increases expression	18301758
C034613	triacsin C	triacsin C results in decreased expression of ILVBL mRNA	decreases expression	16704987

Disease ID	Disease Name	Inference Chemical Name	Inference Score	Publication
MESH:D000014	Abnormalities, Drug-Induced	Phenobarbital	3.90	6195326
MESH:D055371	Acute Lung Injury	pirinixic acid	3.47	18653653
MESH:D018248	Adenoma, Liver Cell	Phenobarbital	11.71	17620307
MESH:D018248	Adenoma, Liver Cell	pirinixic acid	11.71	16434500
MESH:D000799	Angioedema	Acetaminophen	4.36	10982225
MESH:D001321	Autistic Disorder	Acetaminophen	2.23	18445737
MESH:D001321	Autistic Disorder	Arachidonic Acid	2.23	18582451
MESH:D001778	Blood Coagulation Disorders	pirinixic acid	3.47	19483382
MESH:D006528	Carcinoma, Hepatocellular	Acetaminophen	2.99	3084413
MESH:D006528	Carcinoma, Hepatocellular	Phenobarbital	2.99	1701930 17173139 20935162 20007298 6705139
MESH:D002386	Cataract	Acetaminophen	2.75	10977129
MESH:D002493	Central Nervous System Diseases	Phenobarbital	4.67	4080065
MESH:D002779	Cholestasis	pirinixic acid	3.05	19176532
MESH:D003876	Dermatitis, Atopic	pirinixic acid	2.55	18249437
MESH:D056486	Drug-Induced Liver Injury	Acetaminophen	1.65	11743745 19739265 12958197 14725611 10774834 15968718 12392966 19085960 14550746 19416960 19420014 16177239 18713872 17906064 19370779 11461765 16393943 11421492 12594235 17522070 12540782 18071297 15619225 12705907 12153990 16781746 11739529 10915739 16485898 11287661 2444490 11834606 10663392 16109766 11529661 16081117 19164858 14986274 17562736 16227642 19923254
MESH:D056487	Drug-Induced Liver Injury, Chronic	Acetaminophen	4.62	19426721
MESH:D004421	Dystonia	Phenobarbital	4.36	1851702
MESH:D004487	Edema	Arachidonic Acid	8.24	16716910 15177302 11698051 7990266 9599246 9831321
MESH:D004487	Edema	pirinixic acid	8.24	12083418
MESH:D004831	Epilepsies, Myoclonic	Phenobarbital	4.53	3659116
MESH:D004828	Epilepsies, Partial	Phenobarbital	4.39	3922381 11558140
MESH:D004827	Epilepsy	Phenobarbital	3.03	20417680
MESH:D004832	Epilepsy, Absence	Phenobarbital	3.83	6401628
MESH:D017029	Epilepsy, Complex Partial	Phenobarbital	4.67	7750514
MESH:D004830	Epilepsy, Tonic-Clonic	Phenobarbital	4.48	3659116
MESH:D005234	Fatty Liver	pirinixic acid	3.09	20131406 19236843
MESH:D005334	Fever	Arachidonic Acid	4.96	11852909
MESH:D005756	Gastritis	Acetaminophen	4.19	16983495
MESH:D006333	Heart Failure	pirinixic acid	2.71	20558911
MESH:D006529	Hepatomegaly	Phenobarbital	9.90	16109766
MESH:D006529	Hepatomegaly	pirinixic acid	9.90	18467677 16221962 19772884 19176532
MESH:D006930	Hyperalgesia	Acetaminophen	2.95	16870215
MESH:D006943	Hyperglycemia	pirinixic acid	3.49	20558911
MESH:D007249	Inflammation	Arachidonic Acid	3.65	15177302 17371808 9831321
MESH:D007333	Insulin Resistance	pirinixic acid	2.82	16306350
MESH:D007674	Kidney Diseases	Acetaminophen	2.36	12587719 15629191
MESH:D008103	Liver Cirrhosis	Phenobarbital	3.05	21047994
MESH:D008106	Liver Cirrhosis, Experimental	pirinixic acid	1.35	15474484
MESH:D008107	Liver Diseases	Acetaminophen	4.15	12587719 19784758 16611625 19014921 11587558 19460945 16610002 12969438
MESH:D008107	Liver Diseases	Phenobarbital	4.15	19363144
MESH:D017114	Liver Failure, Acute	Acetaminophen	3.54	16871587 17185352
MESH:D008113	Liver Neoplasms	Phenobarbital	4.80	19812893 21047994 19073162 15975961 19482888 8742319
MESH:D008113	Liver Neoplasms	pirinixic acid	4.80	16377806 20007298 15890375
MESH:D008114	Liver Neoplasms, Experimental	Phenobarbital	2.88	18308698 17172636 6150874 1399818 2563599
MESH:D008546	Melanoma, Experimental	Acetaminophen	3.98	19513568
MESH:D009135	Muscular Diseases	pirinixic acid	3.92	16239165
MESH:D009203	Myocardial Infarction	pirinixic acid	2.25	19151258
MESH:D015428	Myocardial Reperfusion Injury	pirinixic acid	3.19	16411023
MESH:D020191	Myoclonic Epilepsies, Progressive	Phenobarbital	4.94	17484760
MESH:D009369	Neoplasms	pirinixic acid	2.08	17405874
MESH:D019636	Neurodegenerative Diseases	Acetaminophen	3.14	18514411
MESH:D009765	Obesity	pirinixic acid	1.87	20558911
MESH:D010018	Osteomalacia	Phenobarbital	4.83	17016548
MESH:D010146	Pain	Acetaminophen	2.65	16870215
MESH:D010190	Pancreatic Neoplasms	Phenobarbital	2.58	16965848
MESH:D011230	Precancerous Conditions	Phenobarbital	3.91	2563599
MESH:D019310	Pseudolymphoma	Phenobarbital	5.02	12752131
MESH:D015427	Reperfusion Injury	pirinixic acid	2.52	19058328
MESH:D012640	Seizures	Phenobarbital	2.89	4039156 3137016 16876388 11442880
MESH:D003294	Seizures, Febrile	Phenobarbital	5.28	6407741
MESH:D012878	Skin Neoplasms	tert-Butylhydroperoxide	2.81	8532709
MESH:D013964	Thyroid Neoplasms	Phenobarbital	3.29	1399818
MESH:D014581	Urticaria	Acetaminophen	3.33	10982225

Pathway ID	Pathway Name
P02748	Isoleucine biosynthesis
P02785	Valine biosynthesis

AutismKB 2.0

Annotation Detail for ILVBL

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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics