Annotation Detail for SLC27A3

Basic Information
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Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
---|
D016604 |
Aflatoxin B1 |
Aflatoxin B1 affects the expression of SLC27A3 protein | affects expression | 20106945
|
C015001 |
arsenite |
arsenite results in decreased expression of SLC27A3 mRNA | decreases expression | 18929588
|
C015001 |
arsenite |
TRP53 protein affects the reaction [arsenite results in decreased expression of SLC27A3 mRNA] | affects reaction|decreases expression | 18929588
|
D016572 |
Cyclosporine |
Cyclosporine results in decreased expression of SLC27A3 mRNA | decreases expression | 20106945
|
D005047 |
Etoposide |
SLC27A3 protein affects the susceptibility to Etoposide | affects response to substance | 16217747
|
D016685 |
Mitomycin |
SLC27A3 protein affects the susceptibility to Mitomycin | affects response to substance | 16217747
|
D010126 |
Ozone |
Ozone results in decreased expression of SLC27A3 mRNA | decreases expression | 17460151
|
C006253 |
pirinixic acid |
[pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of SLC27A3 mRNA | affects binding|decreases expression|increases activity | 19710929
|
C009277 |
sodium arsenate |
sodium arsenate results in decreased expression of SLC27A3 mRNA | decreases expression | 16882884
|
Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
---|
MESH:D055371 |
Acute Lung Injury |
|
pirinixic acid |
3.38 | 18653653 |
MESH:D018248 |
Adenoma, Liver Cell |
|
pirinixic acid |
3.82 | 16434500 |
MESH:D000544 |
Alzheimer Disease |
|
Ozone |
2.48 | 15513908 |
MESH:D001172 |
Arthritis, Rheumatoid |
|
Ozone |
2.60 | 15570426 |
MESH:D001249 |
Asthma |
|
Ozone |
2.70 | 17854713 16373670 |
MESH:D001778 |
Blood Coagulation Disorders |
|
pirinixic acid |
3.39 | 19483382 |
MESH:D019046 |
Bone Marrow Neoplasms |
|
Etoposide |
5.54 | 14601052 |
MESH:D001943 |
Breast Neoplasms |
|
Etoposide |
3.05 | 16322251 |
MESH:D016535 |
Bronchial Hyperreactivity |
|
Ozone |
3.87 | 17626835 19059883 18315731 15516495 18417511 14754758 16777450 |
MESH:D002100 |
Cachexia |
|
Ozone |
5.08 | 16183385 |
MESH:D006528 |
Carcinoma, Hepatocellular |
|
Aflatoxin B1 |
1.98 | 21507988 12619106 12907637 |
MESH:D002471 |
Cell Transformation, Neoplastic |
|
Cyclosporine |
2.68 | 12371664 |
MESH:D002779 |
Cholestasis |
|
Cyclosporine |
8.35 | 19486331 |
MESH:D002779 |
Cholestasis |
|
pirinixic acid |
8.35 | 19176532 |
MESH:D003110 |
Colonic Neoplasms |
|
arsenite |
2.62 | 15037631 |
MESH:D019465 |
Craniofacial Abnormalities |
|
sodium arsenate |
2.73 | 10525206 |
MESH:D003876 |
Dermatitis, Atopic |
|
pirinixic acid |
2.52 | 18249437 |
MESH:D056486 |
Drug-Induced Liver Injury |
|
sodium arsenate |
3.05 | 18186108 |
MESH:D004487 |
Edema |
|
pirinixic acid |
2.72 | 12083418 |
MESH:D005234 |
Fatty Liver |
|
arsenite |
14.59 | 18296743 |
MESH:D005234 |
Fatty Liver |
|
Cyclosporine |
14.59 | 19224547 |
MESH:D005234 |
Fatty Liver |
|
pirinixic acid |
14.59 | 20131406 19236843 |
MESH:D005355 |
Fibrosis |
|
arsenite |
9.93 | 18296743 |
MESH:D005355 |
Fibrosis |
|
Cyclosporine |
9.93 | 12168785 12639820 |
MESH:D005885 |
Gingival Hyperplasia |
|
Cyclosporine |
4.56 | 8708960 |
MESH:D018149 |
Glucose Intolerance |
|
sodium arsenate |
5.34 | 19446573 |
MESH:D006333 |
Heart Failure |
|
pirinixic acid |
2.67 | 20558911 |
MESH:D006457 |
Hemoglobinuria, Paroxysmal |
|
Cyclosporine |
4.76 | 15720958 |
MESH:D006529 |
Hepatomegaly |
|
pirinixic acid |
3.30 | 18467677 16221962 19176532 19772884 |
MESH:D006561 |
Herpes Simplex |
|
Etoposide |
4.90 | 10809021 |
MESH:D006689 |
Hodgkin Disease |
|
Etoposide |
4.08 | 17606976 18180244 15147373 16200630 16135485 |
MESH:D006943 |
Hyperglycemia |
|
pirinixic acid |
3.41 | 20558911 |
MESH:D006973 |
Hypertension |
|
Cyclosporine |
2.17 | 10903974 |
MESH:D007333 |
Insulin Resistance |
|
pirinixic acid |
2.78 | 16306350 |
MESH:D007638 |
Keratoconjunctivitis Sicca |
|
Cyclosporine |
4.82 | 15604871 |
MESH:D007674 |
Kidney Diseases |
|
Cyclosporine |
2.46 | 8314463 10903974 18776723 |
MESH:D007680 |
Kidney Neoplasms |
|
Cyclosporine |
2.93 | 12371664 |
MESH:D008103 |
Liver Cirrhosis |
|
arsenite |
3.54 | 18296743 |
MESH:D008106 |
Liver Cirrhosis, Experimental |
|
pirinixic acid |
1.35 | 15474484 |
MESH:D008113 |
Liver Neoplasms |
|
Aflatoxin B1 |
8.02 | 18177683 9163691 15890375 2125692 |
MESH:D008113 |
Liver Neoplasms |
|
Mitomycin |
8.02 | 15113037 |
MESH:D008113 |
Liver Neoplasms |
|
pirinixic acid |
8.02 | 16377806 15890375 20007298 |
MESH:D008114 |
Liver Neoplasms, Experimental |
|
Aflatoxin B1 |
2.88 | 8603461 |
MESH:D008171 |
Lung Diseases |
|
Ozone |
3.53 | 8266340 19066396 |
MESH:D055370 |
Lung Injury |
|
Ozone |
4.15 | 20417186 |
MESH:D008175 |
Lung Neoplasms |
|
Aflatoxin B1 |
3.71 | 14755239 |
MESH:D008175 |
Lung Neoplasms |
|
arsenite |
3.71 | 16809336 |
MESH:D008175 |
Lung Neoplasms |
|
Ozone |
3.71 | 8597069 7614698 |
MESH:D008223 |
Lymphoma |
|
Etoposide |
4.09 | 12854902 12556972 |
MESH:D008664 |
Metal Metabolism, Inborn Errors |
|
Cyclosporine |
5.16 | 16801185 |
MESH:D008679 |
Metaplasia |
|
Ozone |
5.48 | 10496685 |
MESH:D009135 |
Muscular Diseases |
|
pirinixic acid |
3.81 | 16239165 |
MESH:D009139 |
Musculoskeletal Abnormalities |
|
sodium arsenate |
5.10 | 18186108 |
MESH:D009203 |
Myocardial Infarction |
|
pirinixic acid |
2.22 | 19151258 |
MESH:D015428 |
Myocardial Reperfusion Injury |
|
pirinixic acid |
3.13 | 16411023 |
MESH:D009369 |
Neoplasms |
|
pirinixic acid |
2.05 | 17405874 |
MESH:D009389 |
Neovascularization, Pathologic |
|
arsenite |
4.75 | 15738583 |
MESH:D009402 |
Nephrosis, Lipoid |
|
Cyclosporine |
4.82 | 17954296 |
MESH:D009404 |
Nephrotic Syndrome |
|
Cyclosporine |
3.50 | 19348381 18481113 |
MESH:D009436 |
Neural Tube Defects |
|
sodium arsenate |
4.10 | 11749123 10525206 19446573 18186108 |
MESH:D009765 |
Obesity |
|
pirinixic acid |
1.86 | 20558911 |
MESH:D010190 |
Pancreatic Neoplasms |
|
Etoposide |
6.17 | 19003803 |
MESH:D010190 |
Pancreatic Neoplasms |
|
Mitomycin |
6.17 | 15113037 |
MESH:D010538 |
Peritonitis |
|
Ozone |
4.44 | 16369182 |
MESH:D011014 |
Pneumonia |
|
Ozone |
4.73 | 18007984 18929643 18381685 |
MESH:D011230 |
Precancerous Conditions |
|
Cyclosporine |
3.44 | 12371664 |
MESH:D011471 |
Prostatic Neoplasms |
|
Etoposide |
3.98 | 17172428 |
MESH:D011565 |
Psoriasis |
|
Cyclosporine |
2.30 | 16882103 |
MESH:D015427 |
Reperfusion Injury |
|
pirinixic acid |
2.49 | 19058328 |
MESH:D012512 |
Sarcoma, Ewing's |
|
Etoposide |
4.99 | 14601052 |
MESH:D014605 |
Uveitis |
|
Cyclosporine |
4.36 | 1336536 |
MESH:D014985 |
Xerophthalmia |
|
Cyclosporine |
4.82 | 17120751 |