AutismKB 2.0

Annotation Detail for RAB31


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Basic Information Top
Gene Symbol:RAB31 ( Rab22B )
Gene Full Name: RAB31, member RAS oncogene family
Band: 18p11.22
Quick LinksEntrez ID:11031; OMIM: 605694; Uniprot ID:RAB31_HUMAN; ENSEMBL ID: ENSG00000168461; HGNC ID: 9771
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C031903 1-UFT protocol RAB31 protein results in decreased susceptibility to 1-UFT protocoldecreases response to substance 16734730
D000082 Acetaminophen Acetaminophen affects the expression of RAB31 mRNAaffects expression 17562736
D000643 Ammonium Chloride Ammonium Chloride affects the expression of RAB31 mRNAaffects expression 16483693
D001151 Arsenic RAB31 mRNA results in decreased susceptibility to Arsenicdecreases response to substance 17976673
D001564 Benzo(a)pyrene Benzo(a)pyrene results in increased expression of RAB31 mRNAincreases expression 20106945
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of RAB31 mRNAdecreases expression 20018196
D002084 Butylated Hydroxytoluene Butylated Hydroxytoluene results in decreased expression of RAB31 mRNAdecreases expression 19925653
C423222 cotylenin A cotylenin A results in increased expression of RAB31 mRNAincreases expression 16129123
D004958 Estradiol [Estradiol co-treated with Tetrachlorodibenzodioxin] results in decreased expression of RAB31 mRNAaffects cotreatment|decreases expression 19619570
D004958 Estradiol Estradiol results in increased expression of RAB31 mRNAincreases expression 19619570
C051890 irinotecan RAB31 protein results in decreased susceptibility to irinotecandecreases response to substance 16734730
D007657 Ketone Bodies Ketone Bodies results in decreased expression of RAB31 mRNAdecreases expression 16807920
C008493 methylselenic acid methylselenic acid affects the expression of RAB31 mRNAaffects expression 14617803
C008493 methylselenic acid methylselenic acid results in increased expression of RAB31 mRNAincreases expression 12517777
18548127
D020849 Raloxifene Raloxifene affects the expression of RAB31 mRNAaffects expression 14699072
D013629 Tamoxifen Tamoxifen affects the expression of RAB31 mRNAaffects expression 14699072
D013749 Tetrachlorodibenzodioxin [Estradiol co-treated with Tetrachlorodibenzodioxin] results in decreased expression of RAB31 mRNAaffects cotreatment|decreases expression 19619570
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of RAB31 mRNAdecreases expression 19619570
17517823
D014212 Tretinoin Tretinoin results in increased expression of RAB31 mRNAincreases expression 16129123
D014810 Vitamin E Vitamin E results in increased expression of RAB31 mRNAincreases expression 19244175
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 4.5514745880
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 2.8415322242 14514962 11752688
MESH:D000138 Acidosis Ammonium Chloride 3.5518287403
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 4.2620464547 20127859
MESH:D000230 Adenocarcinoma Estradiol 4.2611473722
MESH:D000236 Adenoma Benzo(a)pyrene 2.646695378
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 3.3716835633
MESH:D018246 Adrenocortical Adenoma Arsenic 5.2117306315
MESH:D000419 Albuminuria Raloxifene 4.5817308373 17451421
MESH:D000505 Alopecia Tretinoin 3.6015955085
MESH:D000544 Alzheimer Disease Raloxifene 2.5415800139
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.9311748828
MESH:D000799 Angioedema Acetaminophen 3.8410982225
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 4.0619183758
MESH:D020261 Arsenic Poisoning Arsenic 2.8616251483 12569548 16835338 18414634
MESH:D001169 Arthritis, Experimental Tretinoin 3.0616412693
MESH:D001172 Arthritis, Rheumatoid Tretinoin 2.2616292516
MESH:D001249 Asthma Tretinoin 2.3416456186
MESH:D050197 Atherosclerosis Arsenic 3.2412928151 19371607
MESH:D001321 Autistic Disorder Acetaminophen 1.4218445737
MESH:D001471 Barrett Esophagus Tretinoin 4.3916935849
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 8.8812125929
MESH:D001778 Blood Coagulation Disorders Tretinoin 8.8816206674 16197459
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.7915340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.7515746008
MESH:D001930 Brain Injuries Raloxifene 4.4616580743
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 2.9517474063 20146248
MESH:D001943 Breast Neoplasms Estradiol 2.9518497071 17289903 17261762 14630087 16675129 12948864 17018787 19861407
MESH:D001943 Breast Neoplasms Raloxifene 2.9515758505 17242785 17049068 15775269 17952589 17440819 16912660 17595753 15572757 16837676 17261762 17893378
MESH:D001943 Breast Neoplasms Tamoxifen 2.9519115204 19244106 11161223 19066611 20135344 17440819 16202921 20065188 18425577 20859285 20005174 19410462 19289846 19221464 15668708 19059307 19011961 16873071 19142967 21152245 18351453 18815881 18984771 21138602 19103187 20544844 19084267 20390343 18855134 19189212 18629630 16818667 19155303 17261762 19189210 17049068 16273361 19487384 17893378 17242785 19200415 18821012 19288272 15565566 18997820
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 2.9520435547
MESH:D001943 Breast Neoplasms Tretinoin 2.9516443354 16166294 16873071
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 4.5816813970
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 4.4516111702
MESH:D002252 Carbon Tetrachloride Poisoning Vitamin E 3.9216050911
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.7816835633
MESH:D002280 Carcinoma, Basal Cell Arsenic 3.5815504454 17687452
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 4.4919066611
MESH:D018236 Carcinoma, Embryonal Tretinoin 5.1616168501
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 8.843084413
MESH:D006528 Carcinoma, Hepatocellular Arsenic 8.8416507464 17306315
MESH:D006528 Carcinoma, Hepatocellular Estradiol 8.8416924424
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 8.8416924424
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 8.841917145
MESH:D002294 Carcinoma, Squamous Cell Arsenic 7.5215504454 18922899 17687452
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 7.5220419170
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 7.5216096774 16051514
MESH:D002295 Carcinoma, Transitional Cell Arsenic 15.8218640142
MESH:D002295 Carcinoma, Transitional Cell Raloxifene 15.8217572228
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 15.8217572228
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.3516120746 18850075 18670907
MESH:D002318 Cardiovascular Diseases Arsenic 7.5117938729 19152805 15738583
MESH:D002318 Cardiovascular Diseases Raloxifene 7.5115775269
MESH:D002340 Carotid Artery Diseases Arsenic 4.2916973168 18022660
MESH:D002386 Cataract Acetaminophen 7.1810977129
MESH:D002386 Cataract Tretinoin 7.1817460283
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 6.6020889678
MESH:D002471 Cell Transformation, Neoplastic Estradiol 6.6018566989
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 4.5816129372
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 3.1416835633
MESH:D002822 Choriocarcinoma Tretinoin 5.1616461808
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 5.7415340226 16354765 8697196 15668235 12621046
MESH:D002972 Cleft Palate Tretinoin 5.749407595
MESH:D003072 Cognition Disorders Raloxifene 4.6015800139
MESH:D003092 Colitis Tretinoin 3.6917035595
MESH:D003110 Colonic Neoplasms irinotecan 2.5917287894 17725105
MESH:D015179 Colorectal Neoplasms irinotecan 2.3616391804 17454858 16303861 18259882 17159606 18509181 15273666
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 3.0417141729 14669216
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 3.7520055451 10048152 15322242
MESH:D019465 Craniofacial Abnormalities Tretinoin 3.759142499 10589399 9211117 9664655 9125849 14991402 9224671 17551590 8800419 16925845
MESH:D019465 Craniofacial Abnormalities Vitamin E 3.7519769572
MESH:D003711 Demyelinating Diseases Tamoxifen 4.3519031437
MESH:D003865 Depressive Disorder, Major Raloxifene 4.1417474826
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 1.6617107852
MESH:D003928 Diabetic Nephropathies Estradiol 14.9219279558
MESH:D003928 Diabetic Nephropathies Raloxifene 14.9217308373 15920148 17451421
MESH:D003928 Diabetic Nephropathies Tamoxifen 14.9219279558
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 3.5416393943 11739529 17522070 11743745 11421492 10663392 14725611 11287661 16781746 19923254 19370779 14550746 16081117 12540782 12392966 2444490 16485898 12153990 12958197 17906064 10774834 11529661 15968718 18713872 15619225 18071297 12705907 19420014 16177239 19164858 14986274 12594235 11461765 10915739 16109766 19739265 19416960 17562736 19085960 11834606 16227642
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 3.5420420201
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.1019426721
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.7411462148
MESH:C538011 Eales disease Vitamin E 4.709068938
MESH:D004487 Edema Raloxifene 6.7915860553
MESH:D004487 Edema Tetrachlorodibenzodioxin 6.7912711302 11000095
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 11.9518230668 16714409 15322242
MESH:D004489 Edema, Cardiac Tretinoin 11.9518230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Raloxifene 9.1915845917
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 9.1919031437
MESH:D016889 Endometrial Neoplasms Estradiol 12.3519148513 11473722 18566989
MESH:D016889 Endometrial Neoplasms Tamoxifen 12.3517893378 19155303 20544844 16202921
MESH:D016889 Endometrial Neoplasms Tretinoin 12.3516569247
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 3.009294722 10568697
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 4.3320426865
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 4.3316530937
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 8.7811564622
MESH:D005124 Eye Abnormalities Tretinoin 8.789664655 16938888
MESH:D005234 Fatty Liver Raloxifene 7.9317473493
MESH:D005234 Fatty Liver Tamoxifen 7.9314986274 19224547
MESH:D052776 Female Urogenital Diseases Tamoxifen 3.2216709447
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.4411858732
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 4.5214745880
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 4.1719069698
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 8.5720067830
MESH:D005355 Fibrosis Tretinoin 8.5717994277
MESH:D005534 Foot Diseases Arsenic 5.566392382
MESH:D005756 Gastritis Acetaminophen 3.6816983495
MESH:D005909 Glioblastoma Tretinoin 2.9917312396
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.5910696789
MESH:D006258 Head and Neck Neoplasms Tretinoin 3.1716096774
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 5.1616084493
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 15.8720471113
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 15.8711294989 10048152
MESH:D006330 Heart Defects, Congenital Tretinoin 15.879664655 14991402
MESH:D006330 Heart Defects, Congenital Vitamin E 15.8716080930
MESH:D006331 Heart Diseases Raloxifene 3.5211110106
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.3211000095
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 2.8815340226 16120746 12621046
MESH:D006548 Hernia, Diaphragmatic Vitamin E 2.6916490937 16863852
MESH:D006558 Herpes Genitalis Estradiol 5.0315709030
MESH:D019584 Hot Flashes Estradiol 10.0517088409
MESH:D019584 Hot Flashes Vitamin E 10.0514716179
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 4.0518606429 8697196 16354765 16959395 15340226
MESH:D006930 Hyperalgesia Acetaminophen 7.5716870215
MESH:D006930 Hyperalgesia Tretinoin 7.5716870215
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 4.5516778211
MESH:D017488 Hyperkeratosis, Epidermolytic Arsenic 4.4417050553
MESH:D006967 Hypersensitivity Butylated Hydroxytoluene 4.4917604070
MESH:D006973 Hypertension Arsenic 8.6416076760 9931084 11953799
MESH:D006973 Hypertension Raloxifene 8.6417577099 15787275
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 8.6418850075 18670907
MESH:D006987 Hypesthesia Arsenic 5.5616093927
MESH:D007249 Inflammation Tamoxifen 4.8519457130
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 4.8512878042 12200463
MESH:D007251 Influenza, Human Vitamin E 4.2116624496
MESH:D007333 Insulin Resistance Estradiol 2.9516393666 16627594
MESH:D007410 Intestinal Diseases Tretinoin 3.7517994277
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 9.8716580747
MESH:D007569 Jaw Abnormalities Tretinoin 9.8717551590 15992940
MESH:D007642 Keratosis Arsenic 4.9816930632 12749816
MESH:D007674 Kidney Diseases Acetaminophen 9.9715629191 12587719
MESH:D007674 Kidney Diseases Estradiol 9.9715618244
MESH:D007674 Kidney Diseases Vitamin E 9.9712488133
MESH:D007680 Kidney Neoplasms Estradiol 7.3315610895
MESH:D007680 Kidney Neoplasms Tamoxifen 7.3318625569
MESH:D007889 Leiomyoma Raloxifene 4.4816973256
MESH:D007938 Leukemia Tretinoin 2.7617143497
MESH:D007951 Leukemia, Myeloid Tretinoin 3.6819285840 16932348 16482212
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 2.0716294345 19850784 17596541
MESH:D015473 Leukemia, Promyelocytic, Acute Arsenic 7.7117339181
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 7.7117712046 19225113 16891316 17506722 9834237 16766008 17649720 15748426 19075265 16331271 16140955 17368321 19035177 16788101 17361223 17301526 19642359 19029980 17217047 16823087 17107899 12679006 17339181 17294898 16935935
MESH:D017880 Limb Deformities, Congenital Tretinoin 3.299224671
MESH:D008064 Lipidoses Tamoxifen 3.1415342952 17567588
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 6.7114716833 14659978
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 6.7118564211
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 6.7112878042
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 6.7118397230 16248980
MESH:D008106 Liver Cirrhosis, Experimental Vitamin E 6.7116169303
MESH:D008107 Liver Diseases Acetaminophen 4.0519014921 16610002 19460945 12587719 12969438 11587558 16611625 19784758
MESH:D008107 Liver Diseases Arsenic 4.0511134558
MESH:D017114 Liver Failure, Acute Acetaminophen 3.2217185352 16871587
MESH:D008113 Liver Neoplasms Arsenic 14.1816368122
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 14.1820195826 21137059
MESH:D008113 Liver Neoplasms Butylated Hydroxytoluene 14.1818177683
MESH:D008113 Liver Neoplasms Tamoxifen 14.1816684651
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 14.1816984957
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 2.0912151625
MESH:D008171 Lung Diseases Vitamin E 3.1616863852
MESH:D008175 Lung Neoplasms Arsenic 8.5417306315 17976673 19168569
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 8.5418816296 20064080 20464547 6695378 20869020 18520028 20135361 18569708 17053015
MESH:D008175 Lung Neoplasms Butylated Hydroxytoluene 8.5419925653 15390079 18597497 19359593 11246140 16337739 11696405
MESH:D008175 Lung Neoplasms Tamoxifen 8.5418625569
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 8.5411884234 19555203
MESH:D008175 Lung Neoplasms Vitamin E 8.5411062179
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 3.7519428831
MESH:D008325 Mammary Neoplasms, Experimental Butylated Hydroxytoluene 10.011500032
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 10.0111408345 11807958 17203775 16891317
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 10.0111731420 19196723 19196722 16827153 14580682
MESH:D020149 Manganese Poisoning Estradiol 12.6519453300
MESH:D020149 Manganese Poisoning Tamoxifen 12.6519453300
MESH:D008527 Medulloblastoma Tretinoin 2.7817453147
MESH:D008545 Melanoma Tamoxifen 3.2712393984 19393235
MESH:D008545 Melanoma Tretinoin 3.2716752155
MESH:D018328 Melanoma, Amelanotic Tamoxifen 4.1715990972
MESH:D008546 Melanoma, Experimental Acetaminophen 3.5519513568
MESH:D008591 Meningomyelocele Tretinoin 4.4116940565
MESH:D018200 Mixed Tumor, Mullerian Raloxifene 5.5515863610
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 3.1716381670
MESH:D052016 Mucositis irinotecan 5.0017159606
MESH:D009101 Multiple Myeloma Raloxifene 3.4216497877
MESH:D009190 Myelodysplastic Syndromes Tretinoin 3.0717596541
MESH:D017202 Myocardial Ischemia Arsenic 8.9415371236
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 8.9412213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 3.2616810080
MESH:D009232 Myxoma Raloxifene 5.5516343187
MESH:D009362 Neoplasm Metastasis irinotecan 5.9218259882
MESH:D009362 Neoplasm Metastasis Tamoxifen 5.9219393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.5119410462
MESH:D009369 Neoplasms Benzo(a)pyrene 4.9611141357
MESH:D009369 Neoplasms Tretinoin 4.9616594593 16946489
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 4.0019196722 19200415 19189210
MESH:D009389 Neovascularization, Pathologic Estradiol 3.7217289903
MESH:D009421 Nervous System Malformations Estradiol 16.2416427766 11399458
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 16.2414600291
MESH:D009421 Nervous System Malformations Tretinoin 16.249125849
MESH:D009436 Neural Tube Defects Arsenic 7.3816620997
MESH:D009436 Neural Tube Defects Tretinoin 7.389142499
MESH:D009447 Neuroblastoma irinotecan 3.478761367
MESH:D019636 Neurodegenerative Diseases Acetaminophen 2.8518514411
MESH:D017599 Neuroectodermal Tumors irinotecan 4.728761367
MESH:D020078 Neurogenic Inflammation Arsenic 4.3617056641
MESH:D010024 Osteoporosis Raloxifene 3.3819059307 17882678 15775268
MESH:D015663 Osteoporosis, Postmenopausal Raloxifene 4.2115579764 17823083 15758505 17893378
MESH:D010051 Ovarian Neoplasms Arsenic 7.8817306315
MESH:D010051 Ovarian Neoplasms Estradiol 7.8819401270
MESH:D010051 Ovarian Neoplasms Tretinoin 7.8816936753
MESH:D010146 Pain Acetaminophen 6.5316870215
MESH:D010146 Pain Tretinoin 6.5316870215
MESH:D010190 Pancreatic Neoplasms Tretinoin 2.4515976015
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.2512520081
MESH:D010523 Peripheral Nervous System Diseases Arsenic 4.1616093927
MESH:D016491 Peripheral Vascular Diseases Arsenic 4.986392382 15371236 16905509
MESH:D011014 Pneumonia Butylated Hydroxytoluene 5.1511893704
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.5418163543
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 3.1811118676 11399792 11896295 11222880
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 3.8720887781
MESH:D011471 Prostatic Neoplasms Arsenic 2.1016140617
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 2.1017292933
MESH:D011471 Prostatic Neoplasms Estradiol 2.1016740699
MESH:D011471 Prostatic Neoplasms methylselenic acid 2.1016205645
MESH:D011471 Prostatic Neoplasms Raloxifene 2.1015731164 16220300 16536755
MESH:D011471 Prostatic Neoplasms Tamoxifen 2.1015067354
MESH:D011471 Prostatic Neoplasms Vitamin E 2.1015084515
MESH:D011507 Proteinuria Arsenic 9.2221343184
MESH:D011507 Proteinuria Tretinoin 9.2216636307
MESH:D011625 Pterygium Tretinoin 4.7816723453
MESH:D011693 Purpura Raloxifene 5.5515770314
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.8218990726
MESH:D012208 Rhabdomyosarcoma Tretinoin 4.0816283617 16116481
MESH:D012871 Skin Diseases Arsenic 5.0216759981 16353154 17548696 19834688 17938729 18709164 17453740 16702368 17050553 15952646 6392382
MESH:D012871 Skin Diseases Vitamin E 5.0218709164
MESH:D012878 Skin Neoplasms Arsenic 13.4817029826 19538983 17050553 15504454 16251483 17976673
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 13.4819755658 10029692
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 13.4816192470
MESH:D012878 Skin Neoplasms Tretinoin 13.4816467112
MESH:D013088 Spermatocele Tamoxifen 4.2916709447
MESH:D013119 Spinal Cord Injuries Tamoxifen 4.0319457130
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 3.4020155912 2093021
MESH:D013274 Stomach Neoplasms irinotecan 3.4015723263
MESH:D013274 Stomach Neoplasms Tretinoin 3.4017261132
MESH:D020521 Stroke Raloxifene 8.6516837676
MESH:D020521 Stroke Vitamin E 8.6516517955
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.9012697716
MESH:D013964 Thyroid Neoplasms Tretinoin 3.0117045167 16026305
MESH:D013978 Tibial Fractures Estradiol 13.7119048282
MESH:D013978 Tibial Fractures Raloxifene 13.7119048282
MESH:D014062 Tongue Neoplasms Tretinoin 3.7716051514
MESH:D014376 Tuberculosis Tretinoin 3.2116040207
MESH:D001749 Urinary Bladder Neoplasms Arsenic 11.8917306315 19322015 19429237 17976673 18640142 11144890 15987713
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 11.8917053015
MESH:D001749 Urinary Bladder Neoplasms Raloxifene 11.8917572228
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 11.898653321 17572228 16712894
MESH:D014581 Urticaria Acetaminophen 2.9610982225
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 3.6616129372
MESH:D014604 Uveal Neoplasms Tretinoin 4.6116752155
MESH:D014652 Vascular Diseases Arsenic 4.7317056641
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.5912125929
MESH:D054556 Venous Thromboembolism Raloxifene 5.2116837676
MESH:D014820 Vitiligo Tretinoin 4.0416761959
MESH:D014846 Vulvar Neoplasms Raloxifene 5.5516343187
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.2515886252
MESH:D009396 Wilms Tumor Tretinoin 3.9516287080
Pathway ID Pathway Name
KEGG:04144 Endocytosis
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA34122
    • No data
    Releated disease ID Related disease Name
    PA446155Precursor Cell Lymphoblastic Leukemia-Lymphoma
    Releated drug ID Related drug Name
    PA450379mercaptopurine
    PA450428methotrexate
    Drug Bank Top

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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