AutismKB 2.0

Annotation Detail for ADRM1


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Basic Information Top
Gene Symbol:ADRM1 ( ARM1,GP110,MGC29536,Rpn13 )
Gene Full Name: adhesion regulating molecule 1
Band: 20q13.33
Quick LinksEntrez ID:11047; OMIM: 610650; Uniprot ID:ADRM1_HUMAN; ENSEMBL ID: ENSG00000130706; HGNC ID: 15759
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of ADRM1 mRNAaffects expression 21346803
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene affects the expression of ADRM1 mRNAaffects expression 21346803
C068805 4-hydroxycoumarin 4-hydroxycoumarin results in decreased expression of ADRM1 mRNAdecreases expression 18492274
D000643 Ammonium Chloride Ammonium Chloride affects the expression of ADRM1 mRNAaffects expression 16483693
D019324 beta-Naphthoflavone beta-Naphthoflavone results in increased expression of ADRM1 mRNAincreases expression 19737606
D016572 Cyclosporine Cyclosporine results in increased expression of ADRM1 mRNAincreases expression 20106945
D004041 Dietary Fats Dietary Fats results in decreased expression of ADRM1 mRNAdecreases expression 18042831
D004958 Estradiol Estradiol results in increased expression of ADRM1 mRNAincreases expression 20106945
C014707 nitrosobenzylmethylamine nitrosobenzylmethylamine results in increased expression of ADRM1 mRNAincreases expression 17616710
C041786 palm oil palm oil results in decreased expression of ADRM1 mRNAdecreases expression 18042831
C006253 pirinixic acid pirinixic acid results in increased expression of ADRM1 mRNAincreases expression 18301758
D011794 Quercetin Quercetin results in decreased expression of ADRM1 mRNAdecreases expression 15309432
D012643 Selenium Selenium results in increased expression of ADRM1 mRNAincreases expression 19244175
D014810 Vitamin E Vitamin E results in increased expression of ADRM1 mRNAincreases expression 19244175
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000138 Acidosis Ammonium Chloride 3.6418287403
MESH:D055371 Acute Lung Injury pirinixic acid 3.1718653653
MESH:D000230 Adenocarcinoma Estradiol 2.1111473722
MESH:D000236 Adenoma beta-Naphthoflavone 3.3619389873
MESH:D018248 Adenoma, Liver Cell pirinixic acid 3.5616434500
MESH:D000743 Anemia, Hemolytic Quercetin 4.2917084956
MESH:D001161 Arteriosclerosis Dietary Fats 3.9615238619
MESH:D001260 Ataxia Telangiectasia Quercetin 5.0615336622
MESH:D001327 Autoimmune Diseases Quercetin 4.4819761891
MESH:D001778 Blood Coagulation Disorders pirinixic acid 3.2019483382
MESH:D001943 Breast Neoplasms Dietary Fats 1.9520435547
MESH:D001943 Breast Neoplasms Estradiol 1.9519861407 12948864 17261762 17018787 16675129 14630087 17289903 18497071
MESH:D001943 Breast Neoplasms Quercetin 1.9518628248
MESH:D002105 Cadmium Poisoning Quercetin 5.6416962696
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 4.5516111702
MESH:D002252 Carbon Tetrachloride Poisoning Vitamin E 4.0016050911
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 6.6616705839
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 6.6616705839
MESH:D006528 Carcinoma, Hepatocellular Estradiol 6.6616924424
MESH:D006528 Carcinoma, Hepatocellular Quercetin 6.6612508355 19519916
MESH:D021441 Carcinoma, Pancreatic Ductal Quercetin 5.0317234771
MESH:D006332 Cardiomegaly Quercetin 3.3519794523
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 11.366135515
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 11.3612371664
MESH:D002471 Cell Transformation, Neoplastic Estradiol 11.3618566989
MESH:D002779 Cholestasis Cyclosporine 7.8919486331
MESH:D002779 Cholestasis pirinixic acid 7.8919176532
MESH:D003092 Colitis Selenium 3.8517936198
MESH:D003110 Colonic Neoplasms Quercetin 2.4316640504 19056647 19440933 17191121 11134977 17148506 15741050
MESH:D015179 Colorectal Neoplasms Quercetin 2.1818852136 18095365
MESH:D019465 Craniofacial Abnormalities Vitamin E 1.9119769572
MESH:D003490 Cyanosis 2,4-dinitrotoluene 11.1418551238
MESH:D003490 Cyanosis 2,6-dinitrotoluene 11.1418551238
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.4518249437
MESH:D003921 Diabetes Mellitus, Experimental Quercetin 3.7819496084
MESH:D003928 Diabetic Nephropathies Estradiol 3.4619279558
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 6.3421346803 18551238
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 6.3421346803 18551238
MESH:D056486 Drug-Induced Liver Injury Selenium 6.3415131321
MESH:D050171 Dyslipidemias Dietary Fats 3.4918367378
MESH:C538011 Eales disease Vitamin E 4.809068938
MESH:D004487 Edema pirinixic acid 2.5312083418
MESH:D016889 Endometrial Neoplasms Estradiol 3.0111473722 18566989 19148513
MESH:D004938 Esophageal Neoplasms nitrosobenzylmethylamine 2.7915264214 15878914 15623463 15547733 16510608 16805852 15547721 16704527 15150132
MESH:D005234 Fatty Liver Cyclosporine 13.3819224547
MESH:D005234 Fatty Liver Dietary Fats 13.3817967931 18296743 19004024 19551842
MESH:D005234 Fatty Liver pirinixic acid 13.3819236843 20131406
MESH:D005355 Fibrosis Cyclosporine 15.2912639820 12168785
MESH:D005355 Fibrosis Dietary Fats 15.2918296743
MESH:D005355 Fibrosis Quercetin 15.2919474275
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.308708960
MESH:D005909 Glioblastoma Quercetin 3.4219804834
MESH:D005910 Glioma Quercetin 3.0717643826
MESH:D006330 Heart Defects, Congenital Vitamin E 3.0116080930
MESH:D006333 Heart Failure pirinixic acid 7.0620558911
MESH:D006333 Heart Failure Selenium 7.0617162251
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.5015720958
MESH:D006529 Hepatomegaly pirinixic acid 3.0718467677 16221962 19772884 19176532
MESH:D006548 Hernia, Diaphragmatic Vitamin E 2.7216863852 16490937
MESH:D006558 Herpes Genitalis Estradiol 5.1315709030
MESH:D019584 Hot Flashes Estradiol 10.3817088409
MESH:D019584 Hot Flashes Vitamin E 10.3814716179
MESH:D006937 Hypercholesterolemia Dietary Fats 3.6521332399
MESH:D006943 Hyperglycemia pirinixic acid 9.4120558911
MESH:D006943 Hyperglycemia Quercetin 9.4111834736 18262572
MESH:D006949 Hyperlipidemias Dietary Fats 3.6721332399
MESH:D006973 Hypertension Cyclosporine 5.3610903974
MESH:D006973 Hypertension Quercetin 5.3618356687
MESH:D007249 Inflammation Dietary Fats 2.4620412841
MESH:D007251 Influenza, Human Quercetin 19.2216624496
MESH:D007251 Influenza, Human Selenium 19.2216624496
MESH:D007251 Influenza, Human Vitamin E 19.2216624496
MESH:D007333 Insulin Resistance Dietary Fats 12.4911836018 18457598
MESH:D007333 Insulin Resistance Estradiol 12.4916627594 16393666
MESH:D007333 Insulin Resistance pirinixic acid 12.4916306350
MESH:D007627 Keloid Quercetin 5.0317086741
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.5415604871
MESH:D007674 Kidney Diseases Cyclosporine 14.718314463 10903974 18776723
MESH:D007674 Kidney Diseases Estradiol 14.7115618244
MESH:D007674 Kidney Diseases Quercetin 14.7116962696
MESH:D007674 Kidney Diseases Vitamin E 14.7112488133
MESH:D007676 Kidney Failure, Chronic Selenium 3.9416518626
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 18.1316705839
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 18.1316705839
MESH:D007680 Kidney Neoplasms Cyclosporine 18.1312371664
MESH:D007680 Kidney Neoplasms Estradiol 18.1315610895
MESH:D007938 Leukemia Quercetin 3.1817468513
MESH:D008103 Liver Cirrhosis Dietary Fats 2.9018296743
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 5.0214659978 14716833
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 5.0215474484
MESH:D008106 Liver Cirrhosis, Experimental Quercetin 5.0212741479
MESH:D008106 Liver Cirrhosis, Experimental Vitamin E 5.0216169303
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 10.907678174
MESH:D008113 Liver Neoplasms beta-Naphthoflavone 10.9021295105 19389873
MESH:D008113 Liver Neoplasms pirinixic acid 10.9020007298 15890375 16377806
MESH:D008113 Liver Neoplasms Quercetin 10.9018980244
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 10.176135515 2876786 2876784
MESH:D008114 Liver Neoplasms, Experimental beta-Naphthoflavone 10.1718164116
MESH:D008114 Liver Neoplasms, Experimental Quercetin 10.1719519916
MESH:D008171 Lung Diseases Vitamin E 3.2116863852
MESH:D008175 Lung Neoplasms Quercetin 2.6716280456
MESH:D008175 Lung Neoplasms Vitamin E 2.6711062179
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 6.1311807958 11408345 16891317 17203775
MESH:D008325 Mammary Neoplasms, Experimental Selenium 6.1315318939
MESH:D020149 Manganese Poisoning Estradiol 4.5819453300
MESH:D008546 Melanoma, Experimental 4-hydroxycoumarin 6.6318492274
MESH:D008654 Mesothelioma Selenium 2.8115107826
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.8816801185
MESH:D009135 Muscular Diseases pirinixic acid 3.5816239165
MESH:D009203 Myocardial Infarction pirinixic acid 5.8019151258
MESH:D009203 Myocardial Infarction Quercetin 5.8019595682
MESH:D015428 Myocardial Reperfusion Injury Estradiol 14.4316810080
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 14.4316411023
MESH:D015428 Myocardial Reperfusion Injury Quercetin 14.4319207477
MESH:D009336 Necrosis 2,4-dinitrotoluene 10.6318551238
MESH:D009336 Necrosis 2,6-dinitrotoluene 10.637678174 18551238
MESH:D009362 Neoplasm Metastasis 4-hydroxycoumarin 5.1118492274
MESH:D009369 Neoplasms pirinixic acid 5.1317405874
MESH:D009369 Neoplasms Quercetin 5.1315185748
MESH:D009389 Neovascularization, Pathologic Estradiol 3.8117289903
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.5417954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.3319348381 18481113
MESH:D009421 Nervous System Malformations Estradiol 3.7211399458 16427766
MESH:D020078 Neurogenic Inflammation Quercetin 4.4217929310
MESH:D009765 Obesity Dietary Fats 4.4717217161 18674790 20518802 21332399 20132043 19632207 18457598 16723640 11836018
MESH:D009765 Obesity pirinixic acid 4.4720558911
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 9.0612819281 16049721
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 9.0616049721
MESH:D015663 Osteoporosis, Postmenopausal Quercetin 4.2819495926
MESH:D010051 Ovarian Neoplasms Estradiol 5.0019401270
MESH:D010051 Ovarian Neoplasms Quercetin 5.0019005980
MESH:D010190 Pancreatic Neoplasms Quercetin 2.8716965848
MESH:D010954 Plasmacytoma Selenium 4.9915087411
MESH:D011230 Precancerous Conditions Cyclosporine 9.2612371664
MESH:D011230 Precancerous Conditions Quercetin 9.2619056647
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 3.9420887781
MESH:D011471 Prostatic Neoplasms Estradiol 2.6016740699
MESH:D011471 Prostatic Neoplasms Quercetin 2.6017292933 14715546
MESH:D011471 Prostatic Neoplasms Vitamin E 2.6015084515
MESH:D011565 Psoriasis Cyclosporine 2.2416882103
MESH:D015427 Reperfusion Injury pirinixic acid 2.4119058328
MESH:D012554 Schistosomiasis japonica Quercetin 5.6416862918
MESH:D012640 Seizures 2,4-dinitrotoluene 5.9918551238
MESH:D012640 Seizures 2,6-dinitrotoluene 5.9918551238
MESH:D012871 Skin Diseases Vitamin E 2.4518709164
MESH:D013274 Stomach Neoplasms nitrosobenzylmethylamine 2.3217575124 12958204
MESH:D020521 Stroke Vitamin E 3.5616517955
MESH:D013978 Tibial Fractures Estradiol 4.7819048282
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 8.4716049721
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 8.4716049721
MESH:D001749 Urinary Bladder Neoplasms Quercetin 8.4716720314
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 12.2710091137
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 12.2710091137
MESH:D014605 Uveitis Cyclosporine 4.081336536
MESH:D015430 Weight Gain Dietary Fats 3.7916723640
MESH:D014985 Xerophthalmia Cyclosporine 4.5417120751
No data
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA24599
    • No data
    Releated disease ID Related disease Name
    PA446155Precursor Cell Lymphoblastic Leukemia-Lymphoma
    No data
    Drug Bank Top

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    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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