AutismKB 2.0

Annotation Detail for C10orf10


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Basic Information Top
Gene Symbol:C10orf10 ( DEPP,FIG )
Gene Full Name: chromosome 10 open reading frame 10
Band: 10q11.21
Quick LinksEntrez ID:11067; OMIM: 611309; Uniprot ID:DEPP_HUMAN; ENSEMBL ID: ENSG00000165507; HGNC ID: 23355
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000639 Amitriptyline Amitriptyline results in increased expression of C10ORF10 mRNAincreases expression 17567588
15342952
D001564 Benzo(a)pyrene Benzo(a)pyrene affects the expression of C10ORF10 mRNAaffects expression 20106945
C095105 bexarotene bexarotene results in increased expression of C10ORF10 mRNAincreases expression 17178900
C084597 chlorcyclizine chlorcyclizine results in increased expression of C10ORF10 mRNAincreases expression 15342952
D002746 Chlorpromazine Chlorpromazine results in increased expression of C10ORF10 mRNAincreases expression 15342952
D002997 Clomipramine Clomipramine results in increased expression of C10ORF10 mRNAincreases expression 15342952
D003024 Clozapine Clozapine results in increased expression of C10ORF10 mRNAincreases expression 15342952
D016572 Cyclosporine Cyclosporine affects the expression of C10ORF10 mRNAaffects expression 20106945
D004316 Doxepin Doxepin results in increased expression of C10ORF10 mRNAincreases expression 17567588
D004958 Estradiol Estradiol results in increased expression of C10ORF10 mRNAincreases expression 16298037
D005424 Flecainide Flecainide results in increased expression of C10ORF10 mRNAincreases expression 15342952
D005473 Fluoxetine Fluoxetine results in increased expression of C10ORF10 mRNAincreases expression 17567588
15342952
C070081 fulvestrant fulvestrant results in decreased expression of C10ORF10 mRNAdecreases expression 16298037
D017313 Fenretinide Fenretinide results in increased expression of C10ORF10 mRNAincreases expression 15958647
D007099 Imipramine Imipramine results in increased expression of C10ORF10 mRNAincreases expression 15342952
17567588
D007213 Indomethacin Indomethacin results in decreased expression of C10ORF10 mRNAdecreases expression 17401462
D007654 Ketoconazole Ketoconazole results in increased expression of C10ORF10 mRNAincreases expression 15342952
D015735 Mifepristone Mifepristone inhibits the reaction [Progesterone results in increased expression of C10ORF10 mRNA]decreases reaction|increases expression 16123073
C029938 nickel sulfate nickel sulfate results in increased expression of C10ORF10 mRNAincreases expression 16780908
D010419 Pentamidine Pentamidine results in increased expression of C10ORF10 mRNAincreases expression 15342952
D010480 Perhexiline Perhexiline results in increased expression of C10ORF10 mRNAincreases expression 15342952
D011374 Progesterone Mifepristone inhibits the reaction [Progesterone results in increased expression of C10ORF10 mRNA]decreases reaction|increases expression 16123073
D011374 Progesterone Progesterone results in increased expression of C10ORF10 mRNAincreases expression 18070364
16123073
D011374 Progesterone Progesterone results in decreased expression of C10ORF10decreases expression 17510236
D011802 Quinidine Quinidine results in increased expression of C10ORF10 mRNAincreases expression 17567588
D020849 Raloxifene Raloxifene results in decreased expression of C10ORF10 mRNAdecreases expression 16298037
D020280 Sertraline Sertraline results in increased expression of C10ORF10 mRNAincreases expression 15342952
17567588
D013629 Tamoxifen Tamoxifen results in decreased expression of C10ORF10 mRNAdecreases expression 16298037
D013629 Tamoxifen Tamoxifen results in increased expression of C10ORF10 mRNAincreases expression 15342952
D013881 Thioridazine Thioridazine results in increased expression of C10ORF10 mRNAincreases expression 15342952
D001371 trans-1,4-Bis(2-chlorobenzaminomethyl)cyclohexane Dihydrochloride trans-1,4-Bis(2-chlorobenzaminomethyl)cyclohexane Dihydrochloride results in increased expression of C10ORF10 mRNAincreases expression 15342952
D015031 Zimeldine Zimeldine results in increased expression of C10ORF10 mRNAincreases expression 15342952
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 4.2814745880
MESH:D055371 Acute Lung Injury nickel sulfate 4.0719131640 12718980 11954676 16100012
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 9.6620127859 20464547
MESH:D000230 Adenocarcinoma Estradiol 9.6611473722
MESH:D000230 Adenocarcinoma Fenretinide 9.6610697514
MESH:D000230 Adenocarcinoma Indomethacin 9.6616537180
MESH:D000236 Adenoma Benzo(a)pyrene 6.356695378
MESH:D000236 Adenoma Indomethacin 6.3511497255
MESH:D000380 Agranulocytosis Clozapine 4.8014617031 16160616 12649775
MESH:D017088 AIDS-Related Opportunistic Infections Pentamidine 6.0911806628
MESH:D000419 Albuminuria Raloxifene 4.3417451421 17308373
MESH:D016301 Alveolar Bone Loss Indomethacin 5.1017225004
MESH:D000544 Alzheimer Disease Indomethacin 4.2617627676 15579461
MESH:D000544 Alzheimer Disease Raloxifene 4.2615800139
MESH:D001008 Anxiety Disorders Fluoxetine 9.2018083778
MESH:D001008 Anxiety Disorders Sertraline 9.2018822694
MESH:D001014 Aortic Aneurysm Indomethacin 4.6010231640
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 10.8519183758
MESH:D017544 Aortic Aneurysm, Abdominal Indomethacin 10.8510388637
MESH:D001145 Arrhythmias, Cardiac Quinidine 4.9318057881 18724381
MESH:D018771 Arthralgia Indomethacin 4.902160914
MESH:D001172 Arthritis, Rheumatoid Indomethacin 2.7611248219
MESH:D001284 Atrophy fulvestrant 4.6011514358
MESH:D001321 Autistic Disorder Fluoxetine 3.1318775368 19232924
MESH:D001321 Autistic Disorder Sertraline 3.1318775368
MESH:D001477 Bartter Syndrome Indomethacin 4.7210684365
MESH:D001929 Brain Edema Indomethacin 4.7611481608
MESH:D020201 Brain Hemorrhage, Traumatic Progesterone 5.0717868700
MESH:D001930 Brain Injuries Progesterone 10.1115665606 15380490 15845082
MESH:D001930 Brain Injuries Raloxifene 10.1116580743
MESH:D002545 Brain Ischemia Indomethacin 4.1612524144
MESH:D001932 Brain Neoplasms Fenretinide 4.1316187019
MESH:D001943 Breast Neoplasms marker/mechanism 16298037
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 5.5617474063 20146248
MESH:D001943 Breast Neoplasms bexarotene 5.5616344269 16818667
MESH:D001943 Breast Neoplasms Estradiol 5.5619861407 16675129 14630087 18497071 17018787 17289903 17261762 12948864
MESH:D001943 Breast Neoplasms Fenretinide 5.5616601279
MESH:D001943 Breast Neoplasms fulvestrant 5.5618984771
MESH:D001943 Breast Neoplasms Indomethacin 5.5617401462
MESH:D001943 Breast Neoplasms Progesterone 5.5615562024 17614352 16175315
MESH:D001943 Breast Neoplasms Raloxifene 5.5617440819 15572757 15775269 15758505 17893378 17261762 17049068 17242785 16912660 17952589 17595753 16837676
MESH:D001943 Breast Neoplasms Tamoxifen 5.5620544844 19189210 19487384 18629630 17049068 19244106 15565566 18821012 19011961 16202921 19410462 19059307 19288272 11161223 21138602 19084267 15668708 16273361 19115204 20065188 16873071 17893378 20005174 19142967 18984771 18815881 17440819 20135344 19200415 19066611 21152245 19155303 17261762 18351453 19103187 18997820 20859285 18855134 19289846 17242785 18425577 19221464 20390343 16818667 19189212
MESH:D002056 Burns Indomethacin 4.4510459503
MESH:D002100 Cachexia Indomethacin 4.7416537180 15141370 15625704 11239499
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 4.2016111702
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 4.2519066611
MESH:D006528 Carcinoma, Hepatocellular Estradiol 6.2816924424
MESH:D006528 Carcinoma, Hepatocellular Fenretinide 6.2817159502 16270382
MESH:D006528 Carcinoma, Hepatocellular Indomethacin 6.2816391822
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 6.2816924424
MESH:D018827 Carcinoma, Lewis Lung Indomethacin 4.4611053908
MESH:D018276 Carcinoma, Medullary Indomethacin 5.0918791128 14736730 11352223
MESH:D002289 Carcinoma, Non-Small-Cell Lung bexarotene 3.1416247446
MESH:D002292 Carcinoma, Renal Cell Indomethacin 3.2517341418
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 7.2320419170
MESH:D002294 Carcinoma, Squamous Cell Fenretinide 7.2316274795
MESH:D002294 Carcinoma, Squamous Cell Indomethacin 7.2315482327 12636206
MESH:D002295 Carcinoma, Transitional Cell Raloxifene 8.7417572228
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 8.7417572228
MESH:D002318 Cardiovascular Diseases Raloxifene 3.2715775269
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 5.9812371664
MESH:D002471 Cell Transformation, Neoplastic Estradiol 5.9818566989
MESH:D018290 Cervical Intraepithelial Neoplasia Fenretinide 5.2116154183
MESH:D002764 Cholecystitis Indomethacin 4.9011181007
MESH:D002779 Cholestasis Cyclosporine 2.7219486331
MESH:D003072 Cognition Disorders Clozapine 10.8217123785
MESH:D003072 Cognition Disorders Raloxifene 10.8215800139
MESH:D003110 Colonic Neoplasms Indomethacin 2.5511260862 15936596 15637740 15786552 15625704 15963497
MESH:D015179 Colorectal Neoplasms Fenretinide 2.9117273769
MESH:D015179 Colorectal Neoplasms Indomethacin 2.9111197048 17054584 18059344 12606626
MESH:D018352 Coronavirus Infections Indomethacin 5.4517302372
MESH:D016757 Death, Sudden, Cardiac Thioridazine 5.6020210726
MESH:D003704 Dementia Thioridazine 5.3411575062
MESH:D003711 Demyelinating Diseases Tamoxifen 4.1019031437
MESH:D003866 Depressive Disorder Amitriptyline 27.6018083778 15014590
MESH:D003866 Depressive Disorder Clomipramine 27.6018083778
MESH:D003866 Depressive Disorder Doxepin 27.6015014590
MESH:D003866 Depressive Disorder Fluoxetine 27.6015014590
MESH:D003866 Depressive Disorder Imipramine 27.6020305041
MESH:D003866 Depressive Disorder Sertraline 27.6015014590 18822694 20305041
MESH:D003865 Depressive Disorder, Major Raloxifene 9.6817474826
MESH:D003865 Depressive Disorder, Major Sertraline 9.6816968574
MESH:D017449 Dermatitis, Allergic Contact nickel sulfate 3.4311298694 16823706 16780908
MESH:D003924 Diabetes Mellitus, Type 2 Clozapine 2.9116402076
MESH:D003928 Diabetic Nephropathies Estradiol 13.7519279558
MESH:D003928 Diabetic Nephropathies Raloxifene 13.7515920148 17308373 17451421
MESH:D003928 Diabetic Nephropathies Tamoxifen 13.7519279558
MESH:D003929 Diabetic Neuropathies Progesterone 4.2317187935
MESH:D003967 Diarrhea Indomethacin 3.557907874 7237001
MESH:D006970 Disorders of Excessive Somnolence Clozapine 5.2915331141
MESH:D056486 Drug-Induced Liver Injury Chlorpromazine 4.7511461765
MESH:D056486 Drug-Induced Liver Injury Ketoconazole 4.7518289764
MESH:D004374 Ductus Arteriosus, Patent Indomethacin 4.8818446180 17190690 12774134 18043480 16326151 16133044
MESH:D004381 Duodenal Ulcer Indomethacin 3.8917151854 11595431 17351913 16699067 11535926 17045617 17329845 17202747 11595415 10671773 11991626
MESH:D050171 Dyslipidemias Clozapine 4.0016402076
MESH:D004487 Edema Amitriptyline 24.0512798668
MESH:D004487 Edema Clomipramine 24.0512798668
MESH:D004487 Edema Fluoxetine 24.0512798668
MESH:D004487 Edema Imipramine 24.0512798668
MESH:D004487 Edema Indomethacin 24.057907874 8273558 16100529 7990266 19703484 10653021 8985016
MESH:D004487 Edema Raloxifene 24.0515860553
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Progesterone 13.9817692515
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Raloxifene 13.9815845917
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 13.9819031437
MESH:D016889 Endometrial Neoplasms Estradiol 6.8218566989 11473722 19148513
MESH:D016889 Endometrial Neoplasms Tamoxifen 6.8217893378 20544844 16202921 19155303
MESH:D004715 Endometriosis Indomethacin 14.1715652904
MESH:D004715 Endometriosis Mifepristone 14.1716134523
MESH:D004715 Endometriosis Progesterone 14.1716134523
MESH:D019446 Endotoxemia Indomethacin 4.2418509659
MESH:D004751 Enteritis Indomethacin 4.4810567023 17763956 16328016
MESH:D020345 Enterocolitis, Necrotizing Indomethacin 4.7217980183
MESH:D004802 Eosinophilia Indomethacin 3.8011298111
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 4.3816530937
MESH:D004938 Esophageal Neoplasms Indomethacin 4.3811005569
MESH:D005234 Fatty Liver Cyclosporine 11.8019224547
MESH:D005234 Fatty Liver Raloxifene 11.8017473493
MESH:D005234 Fatty Liver Tamoxifen 11.8019224547 14986274
MESH:D052776 Female Urogenital Diseases Tamoxifen 3.0816709447
MESH:D005334 Fever Indomethacin 3.8910431976 17627676 11852909
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 4.2614745880
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 3.9219069698
MESH:D005354 Fibrosarcoma Indomethacin 4.6310962813
MESH:D005355 Fibrosis Cyclosporine 8.0412168785 12639820
MESH:D005355 Fibrosis Indomethacin 8.0417994277
MESH:D005499 Folliculitis Indomethacin 4.9011298111
MESH:D005756 Gastritis Indomethacin 4.4815046732
MESH:D005885 Gingival Hyperplasia Cyclosporine 3.958708960
MESH:D005909 Glioblastoma Fenretinide 7.0816187019
MESH:D005909 Glioblastoma Indomethacin 7.0812870263
MESH:D005910 Glioma Indomethacin 3.1216487511 18371953
MESH:D005923 Glomerulosclerosis, Focal Segmental Indomethacin 4.0811849393
MESH:D006073 Gout Indomethacin 5.0911248219
MESH:D006258 Head and Neck Neoplasms Indomethacin 3.5715482327
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 2.5220471113
MESH:D006331 Heart Diseases Raloxifene 3.3611110106
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.1615720958
MESH:D006501 Hepatic Encephalopathy Indomethacin 4.3315633222
MESH:D019698 Hepatitis C, Chronic Indomethacin 4.4315135802
MESH:D006558 Herpes Genitalis Estradiol 4.7615709030
MESH:D006561 Herpes Simplex Chlorpromazine 5.031682908
MESH:D019584 Hot Flashes Estradiol 9.6517088409
MESH:D019584 Hot Flashes Fluoxetine 9.6514716179
MESH:D006816 Huntington Disease Sertraline 5.7618403212
MESH:D006930 Hyperalgesia Indomethacin 3.5712727271
MESH:D034321 Hyperamylasemia Indomethacin 5.4517883296
MESH:D006940 Hyperemia Indomethacin 4.7412524144
MESH:D006948 Hyperkinesis Clozapine 4.6516046005
MESH:D006949 Hyperlipidemias Indomethacin 3.9217546600
MESH:D006973 Hypertension Cyclosporine 4.9610903974
MESH:D006973 Hypertension Raloxifene 4.9615787275 17577099
MESH:D007077 Ileal Diseases Indomethacin 4.7610574470 18306037
MESH:D007079 Ileitis Indomethacin 5.0910651667 16133968 10647630
MESH:D007235 Infant, Premature, Diseases Indomethacin 5.1016133044
MESH:D020244 Infarction, Middle Cerebral Artery Progesterone 4.1415869954
MESH:D007248 Infertility, Male fulvestrant 3.5811514358
MESH:D007249 Inflammation Amitriptyline 22.1612798668
MESH:D007249 Inflammation Clomipramine 22.1612798668
MESH:D007249 Inflammation Fluoxetine 22.1612798668
MESH:D007249 Inflammation Imipramine 22.1612798668
MESH:D007249 Inflammation Indomethacin 22.163291741 12568917 7812673
MESH:D007249 Inflammation Progesterone 22.1615869954
MESH:D007249 Inflammation Tamoxifen 22.1619457130
MESH:D007333 Insulin Resistance Estradiol 2.8016393666 16627594
MESH:D007410 Intestinal Diseases Indomethacin 4.0711855677 17994277 15831440 11713966 11686837 17329856 15610444 18236018 10210152
MESH:D019586 Intracranial Hypertension Indomethacin 5.1015241188
MESH:D007579 Jejunal Diseases Indomethacin 4.7618306037 10574470 16133968
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.1715604871
MESH:D007674 Kidney Diseases Cyclosporine 9.248314463 10903974 18776723
MESH:D007674 Kidney Diseases Estradiol 9.2415618244
MESH:D007674 Kidney Diseases Indomethacin 9.2417190690
MESH:D007680 Kidney Neoplasms Cyclosporine 11.1512371664
MESH:D007680 Kidney Neoplasms Estradiol 11.1515610895
MESH:D007680 Kidney Neoplasms Tamoxifen 11.1518625569
MESH:D007889 Leiomyoma Raloxifene 4.2516973256
MESH:D007896 Leishmaniasis Pentamidine 5.1715340016
MESH:D016773 Leishmaniasis, Cutaneous Indomethacin 13.1412228301 11703811 10320625
MESH:D016773 Leishmaniasis, Cutaneous Ketoconazole 13.142166429 1311351 19744259 8889330
MESH:D016773 Leishmaniasis, Cutaneous Pentamidine 13.148889330 11806628 10617787 12453009
MESH:D007897 Leishmaniasis, Mucocutaneous Pentamidine 5.8110881086
MESH:D007898 Leishmaniasis, Visceral Ketoconazole 8.2911332679
MESH:D007898 Leishmaniasis, Visceral Pentamidine 8.2916131481 1659303 12803856 7498017 10467834 7715298
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive Indomethacin 3.7316572323 10785260 15631656
MESH:D015470 Leukemia, Myeloid, Acute Indomethacin 2.5918360721
MESH:D007964 Leukocytosis Indomethacin 5.1016537180
MESH:D007969 Leukomalacia, Periventricular Indomethacin 5.4517980183
MESH:D007972 Leukoplakia, Oral Fenretinide 5.7816707609
MESH:D008064 Lipidoses marker/mechanism 15342952 16919414
MESH:D008064 Lipidoses Amitriptyline 79.5917567588 15342952
MESH:D008064 Lipidoses chlorcyclizine 79.5915342952
MESH:D008064 Lipidoses Chlorpromazine 79.5915342952 17567588
MESH:D008064 Lipidoses Clomipramine 79.5917567588 15342952
MESH:D008064 Lipidoses Clozapine 79.5917567588
MESH:D008064 Lipidoses Fluoxetine 79.5915342952 17567588
MESH:D008064 Lipidoses Imipramine 79.5915342952 17567588
MESH:D008064 Lipidoses Ketoconazole 79.5917567588
MESH:D008064 Lipidoses Perhexiline 79.5915342952 17567588
MESH:D008064 Lipidoses Sertraline 79.5917567588
MESH:D008064 Lipidoses Tamoxifen 79.5917567588 15342952
MESH:D008064 Lipidoses Thioridazine 79.5917567588 15342952
MESH:D008064 Lipidoses trans-1,4-Bis(2-chlorobenzaminomethyl)cyclohexane Dihydrochloride 79.5915342952
MESH:D008064 Lipidoses Zimeldine 79.5915342952
MESH:D008101 Liver Abscess, Amebic Indomethacin 5.4511479899
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 3.4014716833 14659978
MESH:D008106 Liver Cirrhosis, Experimental Indomethacin 3.4018194892
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 3.4018564211
MESH:D008107 Liver Diseases Chlorpromazine 3.6114986274
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 4.1820195826 21137059
MESH:D008113 Liver Neoplasms Tamoxifen 4.1816684651
MESH:D008133 Long QT Syndrome Quinidine 8.6811989578 15350150
MESH:D008133 Long QT Syndrome Thioridazine 8.6820210726
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 4.646695378 17053015 20064080 18520028 20869020 20464547 20135361 18816296 18569708
MESH:D008175 Lung Neoplasms bexarotene 4.6417849452
MESH:D008175 Lung Neoplasms Indomethacin 4.6411497255 11053908 16537180
MESH:D008175 Lung Neoplasms Tamoxifen 4.6418625569
MESH:D016410 Lymphoma, T-Cell, Cutaneous bexarotene 4.8911161223
MESH:D016778 Malaria, Falciparum Perhexiline 10.9116882315
MESH:D016778 Malaria, Falciparum Thioridazine 10.9116882315
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 3.5019428831
MESH:D008325 Mammary Neoplasms, Experimental bexarotene 17.0619196723 15591091 19196722
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 17.0616891317 17203775 11807958 11408345
MESH:D008325 Mammary Neoplasms, Experimental Fenretinide 17.0610697514
MESH:D008325 Mammary Neoplasms, Experimental Progesterone 17.0617203775 11408345
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 17.0614580682 16827153 19196722 19196723 11731420
MESH:D020149 Manganese Poisoning Estradiol 11.7619453300
MESH:D020149 Manganese Poisoning Tamoxifen 11.7619453300
MESH:D008545 Melanoma Fenretinide 3.4616270382
MESH:D008545 Melanoma Tamoxifen 3.4612393984 19393235
MESH:D018328 Melanoma, Amelanotic Tamoxifen 3.9215990972
MESH:D001523 Mental Disorders Amitriptyline 44.3516856516
MESH:D001523 Mental Disorders Chlorpromazine 44.3516856516
MESH:D001523 Mental Disorders Clomipramine 44.3516856516
MESH:D001523 Mental Disorders Clozapine 44.3516856516
MESH:D001523 Mental Disorders Doxepin 44.3516856516
MESH:D001523 Mental Disorders Fluoxetine 44.3516856516
MESH:D001523 Mental Disorders Imipramine 44.3516856516
MESH:D001523 Mental Disorders Sertraline 44.3516856516
MESH:D001523 Mental Disorders Thioridazine 44.3516856516
MESH:D024821 Metabolic Syndrome X Clozapine 4.2019142101
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.5216801185
MESH:D008881 Migraine Disorders Amitriptyline 7.6918803445
MESH:D008881 Migraine Disorders Indomethacin 7.6911903285
MESH:D018200 Mixed Tumor, Mullerian Raloxifene 5.2915863610
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 13.3616381670
MESH:D009062 Mouth Neoplasms Fenretinide 13.3616274795
MESH:D009062 Mouth Neoplasms Indomethacin 13.3612636206
MESH:D009101 Multiple Myeloma Raloxifene 3.2616497877
MESH:D009175 Mycoplasma Infections Chlorpromazine 5.7310773494
MESH:D015428 Myocardial Reperfusion Injury Estradiol 3.0816810080
MESH:D009207 Myoclonus Fluoxetine 5.618041377
MESH:D009232 Myxoma Raloxifene 5.2916343187
MESH:D009362 Neoplasm Metastasis Indomethacin 5.6011053908 11239499 16537180
MESH:D009362 Neoplasm Metastasis Tamoxifen 5.6019393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.4319410462
MESH:D009369 Neoplasms Benzo(a)pyrene 4.8911141357
MESH:D009369 Neoplasms Fenretinide 4.8915958647 17353921
MESH:D009374 Neoplasms, Experimental Indomethacin 3.8815625704 10663608
MESH:D009376 Neoplasms, Hormone-Dependent bexarotene 10.0419196722
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 10.0419200415 19196722 19189210
MESH:D009389 Neovascularization, Pathologic Estradiol 3.4717289903
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.1717954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.0619348381 18481113
MESH:D009421 Nervous System Malformations Estradiol 3.4011399458 16427766
MESH:D019636 Neurodegenerative Diseases Indomethacin 3.7312349958
MESH:D009472 Neuronal Ceroid-Lipofuscinoses Fenretinide 5.4116303764
MESH:D009765 Obesity Clozapine 2.9518515891 19142110
MESH:D009771 Obsessive-Compulsive Disorder Fluoxetine 5.2120418887
MESH:D007752 Obstetric Labor, Premature Indomethacin 4.906374098
MESH:D010003 Osteoarthritis Indomethacin 3.517009135
MESH:D010024 Osteoporosis Raloxifene 3.2419059307 17882678 15775268
MESH:D015663 Osteoporosis, Postmenopausal Raloxifene 3.9817893378 17823083 15579764 15758505
MESH:D010051 Ovarian Neoplasms Estradiol 10.6619401270
MESH:D010051 Ovarian Neoplasms Fenretinide 10.6616133793
MESH:D010051 Ovarian Neoplasms Mifepristone 10.6616525653
MESH:D010051 Ovarian Neoplasms Progesterone 10.6616525653 17393432
MESH:D010146 Pain Amitriptyline 19.0712798668
MESH:D010146 Pain Clomipramine 19.0712798668
MESH:D010146 Pain Fluoxetine 19.0712798668
MESH:D010146 Pain Imipramine 19.0712798668
MESH:D010146 Pain Indomethacin 19.0717627676 13679232 17440234 3291741
MESH:D010149 Pain, Postoperative Indomethacin 4.4112538197 18702446
MESH:D010190 Pancreatic Neoplasms Fenretinide 3.2615580305
MESH:D010195 Pancreatitis Indomethacin 3.6817883296 15028970
MESH:D010257 Paraneoplastic Syndromes Indomethacin 5.4516537180
MESH:D020734 Parkinsonian Disorders Indomethacin 3.8912349958
MESH:D051302 Paroxysmal Hemicrania Indomethacin 5.4511903285
MESH:D010437 Peptic Ulcer Indomethacin 4.8811148446
MESH:D010518 Periodontitis Indomethacin 4.6517225004
MESH:D020774 Pick Disease of the Brain Fluoxetine 5.748041377
MESH:D011020 Pneumonia, Pneumocystis Pentamidine 6.4515340016
MESH:D011230 Precancerous Conditions Cyclosporine 3.0012371664
MESH:D047928 Premature Birth Indomethacin 4.8717000239
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 3.6520887781
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 1.8917292933
MESH:D011471 Prostatic Neoplasms Estradiol 1.8916740699
MESH:D011471 Prostatic Neoplasms Fenretinide 1.8917024972
MESH:D011471 Prostatic Neoplasms Ketoconazole 1.8917404083
MESH:D011471 Prostatic Neoplasms Raloxifene 1.8916220300 16536755 15731164
MESH:D011471 Prostatic Neoplasms Tamoxifen 1.8915067354
MESH:D011507 Proteinuria Indomethacin 3.9211849393
MESH:D011565 Psoriasis Cyclosporine 2.1416882103
MESH:D011618 Psychotic Disorders Clozapine 8.9015331141
MESH:D011618 Psychotic Disorders Thioridazine 8.9016882315
MESH:D011693 Purpura Raloxifene 5.2915770314
MESH:D012162 Retinal Degeneration Fenretinide 4.2116303925
MESH:D012468 Salivary Gland Neoplasms Progesterone 2.7618045962
MESH:D012559 Schizophrenia Clozapine 2.7019369910 17726453 11151749 20580759 18806925 16141801 20168265 18855531 17667964 20452607 20521320 11763009 17123785 20521326 20107430
MESH:D020230 Serotonin Syndrome Fluoxetine 5.638704074
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 5.5910029692 19755658
MESH:D012878 Skin Neoplasms Fenretinide 5.5916467112
MESH:D012892 Sleep Deprivation Imipramine 5.9319798453
MESH:D007319 Sleep Initiation and Maintenance Disorders Amitriptyline 10.2015341891
MESH:D007319 Sleep Initiation and Maintenance Disorders Doxepin 10.2015341891
MESH:D013088 Spermatocele Tamoxifen 4.0316709447
MESH:D013119 Spinal Cord Injuries Progesterone 9.9915862959 16503802
MESH:D013119 Spinal Cord Injuries Tamoxifen 9.9919457130
MESH:D013272 Stomach Diseases Indomethacin 4.1616113693 10192188 15038085 17638125 17207306 16280098 15472012 16184426 10215738 18209964 10486359 18545984 17160473
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 2.482093021 20155912
MESH:D013274 Stomach Neoplasms Indomethacin 2.4815609394
MESH:D013276 Stomach Ulcer Indomethacin 3.3612077510 18087811 15138204 14567935 15104355 17654042 11906479 18299717 18431645 18543354 17627676 11523592 17977527 15255614 1323529 16252198 16631530 10750652 17918041 12498302 16755016 11145282 16397915 18237397 17895592 17657623 16169175 17135157 10878458 11595415 12787963 18193104 16934674 16150113 18181030 11729361 11595431 18726076 18209962 12467913 10423059 12500499
MESH:D020521 Stroke Raloxifene 3.6216837676
MESH:D017180 Tachycardia, Ventricular Thioridazine 5.4520210726
MESH:D013964 Thyroid Neoplasms Indomethacin 3.3918791128 14736730 11352223
MESH:D013978 Tibial Fractures Estradiol 12.8219048282
MESH:D013978 Tibial Fractures Raloxifene 12.8219048282
MESH:D016171 Torsades de Pointes Flecainide 5.8017467628
MESH:D014352 Trypanosomiasis Pentamidine 6.2515340016
MESH:D014456 Ulcer Indomethacin 4.6317380554 10574470
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 11.1117053015
MESH:D001749 Urinary Bladder Neoplasms Fenretinide 11.1116720286
MESH:D001749 Urinary Bladder Neoplasms Raloxifene 11.1117572228
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 11.118653321 17572228 16712894
MESH:D002583 Uterine Cervical Neoplasms Fenretinide 4.3416154183
MESH:D014605 Uveitis Cyclosporine 3.721336536
MESH:D054556 Venous Thromboembolism Raloxifene 4.9416837676
MESH:D014839 Vomiting Indomethacin 4.4811897121
MESH:D014846 Vulvar Neoplasms Raloxifene 5.2916343187
MESH:D015430 Weight Gain Clozapine 4.2520107430 17502770 16141801 20564506 16402076 20521320
MESH:D015431 Weight Loss Clozapine 4.8117933447
MESH:D014985 Xerophthalmia Cyclosporine 4.1717120751
No data
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA128394583
    • No data
    Releated disease ID Related disease Name
    PA446155Precursor Cell Lymphoblastic Leukemia-Lymphoma
    No data
    Drug Bank Top

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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