Gene Symbol:	CHD3 ( Mi-2a,Mi2-ALPHA,ZFH )
Gene Full Name:	chromodomain helicase DNA binding protein 3
Band:	17p13.1
Quick Links	Entrez ID:1107; OMIM: 602120; Uniprot ID:CHD3_HUMAN; ENSEMBL ID: ENSG00000170004; HGNC ID: 1918
Relate to Another Database:	SFARIGene; denovo-db

Chemical ID	Chemical Name	Interaction	Interaction Action	Publication
D006861	Hydrogen Peroxide	Hydrogen Peroxide results in decreased expression of CHD3 mRNA	decreases expression	15458575
D010269	Paraquat	Paraquat results in decreased expression of CHD3 mRNA	decreases expression	15458575
C006253	pirinixic acid	[pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of CHD3 mRNA	affects binding\|increases activity\|increases expression	19710929
D012643	Selenium	Selenium results in increased expression of CHD3 mRNA	increases expression	19244175
D014415	Tunicamycin	Tunicamycin results in decreased expression of CHD3 mRNA	decreases expression	15458575

Disease ID	Disease Name	Inference Chemical Name	Inference Score	Publication
MESH:D055371	Acute Lung Injury	pirinixic acid	3.52	18653653
MESH:D018248	Adenoma, Liver Cell	pirinixic acid	4.02	16434500
MESH:D000382	Agricultural Workers' Diseases	Paraquat	4.30	11874814
MESH:D001778	Blood Coagulation Disorders	pirinixic acid	3.52	19483382
MESH:D002318	Cardiovascular Diseases	Hydrogen Peroxide	3.75	16936243
MESH:D002779	Cholestasis	pirinixic acid	3.08	19176532
MESH:D003092	Colitis	Selenium	4.26	17936198
MESH:D003876	Dermatitis, Atopic	pirinixic acid	2.56	18249437
MESH:D056486	Drug-Induced Liver Injury	Selenium	2.25	15131321
MESH:D004487	Edema	pirinixic acid	2.85	12083418
MESH:D005234	Fatty Liver	pirinixic acid	3.14	19236843 20131406
MESH:D005911	Gliosis	Paraquat	5.78	11124998
MESH:D006333	Heart Failure	pirinixic acid	7.62	20558911
MESH:D006333	Heart Failure	Selenium	7.62	17162251
MESH:D006529	Hepatomegaly	pirinixic acid	3.48	16221962 19772884 18467677 19176532
MESH:D006943	Hyperglycemia	pirinixic acid	3.53	20558911
MESH:D007248	Infertility, Male	Paraquat	3.47	4850670
MESH:D007251	Influenza, Human	Selenium	4.81	16624496
MESH:D007333	Insulin Resistance	pirinixic acid	2.85	16306350
MESH:D007676	Kidney Failure, Chronic	Hydrogen Peroxide	11.30	16518626
MESH:D007676	Kidney Failure, Chronic	Selenium	11.30	16518626
MESH:D008106	Liver Cirrhosis, Experimental	pirinixic acid	1.35	15474484
MESH:D008113	Liver Neoplasms	pirinixic acid	1.92	16377806 15890375 20007298
MESH:D008325	Mammary Neoplasms, Experimental	Selenium	2.97	15318939
MESH:D008654	Mesothelioma	Selenium	2.90	15107826
MESH:D009135	Muscular Diseases	pirinixic acid	3.99	16239165
MESH:D009203	Myocardial Infarction	pirinixic acid	2.26	19151258
MESH:D015428	Myocardial Reperfusion Injury	pirinixic acid	3.22	16411023
MESH:D009369	Neoplasms	pirinixic acid	2.09	17405874
MESH:D009410	Nerve Degeneration	Paraquat	3.99	16893418
MESH:D009765	Obesity	pirinixic acid	1.88	20558911
MESH:D010212	Papilloma	Hydrogen Peroxide	4.57	12065085
MESH:D010300	Parkinson Disease	Paraquat	2.92	11181820 12911755 16510128 11445065 11124998 16140633 15824117 15451049
MESH:D010302	Parkinson Disease, Secondary	Paraquat	4.91	16190885
MESH:D010954	Plasmacytoma	Selenium	5.50	15087411
MESH:D011014	Pneumonia	Paraquat	4.99	12504350
MESH:D011658	Pulmonary Fibrosis	Paraquat	3.02	17997886 16324872
MESH:D015427	Reperfusion Injury	pirinixic acid	2.53	19058328
MESH:D012128	Respiratory Distress Syndrome, Adult	Paraquat	4.31	11700416
MESH:D012135	Respiratory Sounds	Paraquat	4.54	11874814
MESH:D012162	Retinal Degeneration	Paraquat	4.13	16458197
MESH:D012878	Skin Neoplasms	Hydrogen Peroxide	3.21	12065085

AutismKB 2.0

Annotation Detail for CHD3

Simple Query:

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics