AutismKB 2.0

Annotation Detail for PLA2G16


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:PLA2G16 ( AdPLA,H-REV107-1,HRASLS3,HREV107,HREV107-3,MGC118754 )
Gene Full Name: phospholipase A2, group XVI
Band: 11q12.3-q13.1
Quick LinksEntrez ID:11145; OMIM: NA; Uniprot ID:PAG16_HUMAN; ENSEMBL ID: ENSG00000176485; HGNC ID: 17825
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of PLA2G16 mRNAaffects expression 21346803
C035207 4-amino-2,6-dinitrotoluene 4-amino-2,6-dinitrotoluene affects the expression of PLA2G16 mRNAaffects expression 21346803
D000643 Ammonium Chloride Ammonium Chloride affects the expression of PLA2G16 mRNAaffects expression 16483693
D001205 Ascorbic Acid [Quercetin co-treated with Ascorbic Acid] results in increased expression of PLA2G16 mRNAaffects cotreatment|increases expression 17639512
D002251 Carbon Tetrachloride Carbon Tetrachloride affects the expression of PLA2G16 mRNAaffects expression 17484886
D016572 Cyclosporine Cyclosporine results in decreased expression of PLA2G16 mRNAdecreases expression 20106945
D004052 Diethylnitrosamine Diethylnitrosamine results in decreased expression of PLA2G16 mRNAdecreases expression 18691550
D004052 Diethylnitrosamine Diethylnitrosamine results in increased expression of PLA2G16 mRNAincreases expression 17942915
D004052 Diethylnitrosamine IKBKB protein inhibits the reaction [Diethylnitrosamine results in decreased expression of PLA2G16 mRNA]decreases expression|decreases reaction 18691550
D004052 Diethylnitrosamine MAPK14 protein inhibits the reaction [Diethylnitrosamine results in decreased expression of PLA2G16 mRNA]decreases expression|decreases reaction 18691550
D004052 Diethylnitrosamine MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of PLA2G16 mRNA]decreases reaction|increases expression 17942915
D004052 Diethylnitrosamine Diethylnitrosamine results in decreased expression of PLA2G16 mRNAdecreases expression 19638242
D000431 Ethanol [Fish Oils co-treated with Ethanol] results in increased expression of PLA2G16 mRNAaffects cotreatment|increases expression 17347304
D005395 Fish Oils [Fish Oils co-treated with Ethanol] results in increased expression of PLA2G16 mRNAaffects cotreatment|increases expression 17347304
C029938 nickel sulfate nickel sulfate results in increased expression of PLA2G16 mRNAincreases expression 16780908
C014707 nitrosobenzylmethylamine nitrosobenzylmethylamine results in increased expression of PLA2G16 mRNAincreases expression 17616710
D010795 Phthalic Acids Phthalic Acids results in decreased expression of PLA2G16 mRNAdecreases expression 15728792
C006253 pirinixic acid pirinixic acid results in decreased expression of PLA2G16 mRNAdecreases expression 17426115
C006253 pirinixic acid pirinixic acid results in increased expression of PLA2G16 mRNAincreases expression 18301758
D011794 Quercetin [Quercetin co-treated with Ascorbic Acid] results in increased expression of PLA2G16 mRNAaffects cotreatment|increases expression 17639512
D012643 Selenium Selenium results in increased expression of PLA2G16 mRNAincreases expression 19244175
C009277 sodium arsenate sodium arsenate results in decreased expression of PLA2G16 mRNAdecreases expression 12727804
C017947 sodium arsenite sodium arsenite results in decreased expression of PLA2G16 mRNAdecreases expression 12727804
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of PLA2G16 mRNAincreases expression 20106945
C402769 tipifarnib tipifarnib results in increased expression of PLA2G16 mRNAincreases expression 16403772
D014635 Valproic Acid Valproic Acid results in increased expression of PLA2G16 mRNAincreases expression 19101580
D014810 Vitamin E Vitamin E results in increased expression of PLA2G16 mRNAincreases expression 19244175
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced 4-amino-2,6-dinitrotoluene 19.487525203
MESH:D000014 Abnormalities, Drug-Induced Ethanol 19.4818926900 17676605
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 19.4814514962 15322242 11752688
MESH:D000014 Abnormalities, Drug-Induced Valproic Acid 19.488875741
MESH:D000015 Abnormalities, Multiple Valproic Acid 3.8319490988
MESH:D000138 Acidosis Ammonium Chloride 10.1118287403
MESH:D000138 Acidosis Ethanol 10.1111192467
MESH:D055371 Acute Lung Injury nickel sulfate 8.7919131640 11954676 16100012 12718980
MESH:D055371 Acute Lung Injury pirinixic acid 8.7918653653
MESH:D000236 Adenoma Diethylnitrosamine 2.7910737359 6695378
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 16.6519052882 19061943 17620307 17162532 18056438 16434500
MESH:D018248 Adenoma, Liver Cell pirinixic acid 16.6516434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 16.6516835633
MESH:D000310 Adrenal Gland Neoplasms sodium arsenite 4.5915276417
MESH:D018246 Adrenocortical Adenoma sodium arsenite 4.8016712894 17306315
MESH:D020268 Alcohol-Induced Disorders, Nervous System Ethanol 5.2115451040 15451039
MESH:D000550 Amblyopia Valproic Acid 5.1317688650
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.8511748828
MESH:D000743 Anemia, Hemolytic Quercetin 4.1417084956
MESH:D000853 Anophthalmos Ethanol 4.7115513904
MESH:D001008 Anxiety Disorders Ethanol 8.6911141031
MESH:D001008 Anxiety Disorders Valproic Acid 8.6917497229
MESH:D001260 Ataxia Telangiectasia Quercetin 4.8715336622
MESH:D001289 Attention Deficit Disorder with Hyperactivity Phthalic Acids 4.2920106747
MESH:D001321 Autistic Disorder Valproic Acid 2.0118985861 17157402 16609825 18940202 20603192 17507914 18775368 18316065 15238991 19232924 18558336 18396377 17688650 18177632 19460635
MESH:D001327 Autoimmune Diseases Quercetin 4.3019761891
MESH:D001714 Bipolar Disorder Valproic Acid 3.0220046352 17594078
MESH:D001778 Blood Coagulation Disorders pirinixic acid 8.4319483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 8.4312125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.6915340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 7.7915746008
MESH:D001848 Bone Diseases, Developmental Valproic Acid 7.798888407
MESH:D001943 Breast Neoplasms Ascorbic Acid 1.9816443354
MESH:D001943 Breast Neoplasms Diethylnitrosamine 1.9817474063
MESH:D001943 Breast Neoplasms Quercetin 1.9818628248
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 1.9820435547
MESH:D002056 Burns Ethanol 4.5416374292
MESH:D002105 Cadmium Poisoning Quercetin 5.4416962696
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 9.5716192424 16227642 16050911 15673190 18705752 15721981 16097048 3786805 16124888 10355542 16011737 15700767
MESH:D002252 Carbon Tetrachloride Poisoning Vitamin E 9.5716050911
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.7116835633
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 11.1716705839
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 11.1718788625
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 11.1710737359 17055752 16540662 17173139 16830150 10672840 18665156 19052882 18978308 20935162 20512989 18506893 16935385 17428255 19418558 17138121 18971187 19394651 16698587 18785209 19208518 19539802 19335982 16288022 16328049 19701751 16779866 20524982 11831363 20084675 20432363 3084413 18494052 18788625 16502159 19919837 20727157 18393292 20007298 19171122 18691550 19519916 16681979 17978847 3581430 16807293 20214788 20514400 18056438 17761372 21159647 18210153 20101231 16878318 19822196 16569478 17162532 19107877 19383236
MESH:D006528 Carcinoma, Hepatocellular Ethanol 11.1718788625 15763234 15289165
MESH:D006528 Carcinoma, Hepatocellular Quercetin 11.1712508355 19519916
MESH:D006528 Carcinoma, Hepatocellular sodium arsenite 11.1717306315 16507464 15276417
MESH:D021441 Carcinoma, Pancreatic Ductal Quercetin 4.8517234771
MESH:D002294 Carcinoma, Squamous Cell sodium arsenite 2.3518572023
MESH:D006332 Cardiomegaly Ethanol 11.1119332462
MESH:D006332 Cardiomegaly Quercetin 11.1119794523
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 11.1118670907 18850075 16120746
MESH:D002386 Cataract 4-amino-2,6-dinitrotoluene 3.5714694615
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 10.7412371664
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 10.747505956 2727394 17174075 21159647
MESH:D002471 Cell Transformation, Neoplastic sodium arsenite 10.7420056578 19524636
MESH:D002659 Child Development Disorders, Pervasive Valproic Acid 2.6720734317
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 9.0119052882
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 9.0116835633
MESH:D002779 Cholestasis Cyclosporine 7.4919486331
MESH:D002779 Cholestasis pirinixic acid 7.4919176532
MESH:D002971 Cleft Lip Ethanol 3.5315513904
MESH:D002972 Cleft Palate Ethanol 5.8015513904
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 5.8015340226 8697196 15668235 12621046 16354765
MESH:D003092 Colitis Selenium 3.6717936198
MESH:D003110 Colonic Neoplasms Quercetin 2.4017191121 15741050 19056647 19440933 16640504 11134977 17148506
MESH:D015179 Colorectal Neoplasms Quercetin 2.1818852136 18095365
MESH:D003139 Common Cold Ascorbic Acid 5.3717323712
MESH:D000013 Congenital Abnormalities 4-amino-2,6-dinitrotoluene 8.8715095906
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 8.8714669216 17141729
MESH:D019465 Craniofacial Abnormalities Ethanol 7.2215451040 11198716 15513904 15451039 11873399 19302082 10194807
MESH:D019465 Craniofacial Abnormalities sodium arsenate 7.2210525206
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 7.2210048152 20055451 15322242
MESH:D019465 Craniofacial Abnormalities Valproic Acid 7.228888407 17688650 16575769
MESH:D019465 Craniofacial Abnormalities Vitamin E 7.2219769572
MESH:D003490 Cyanosis 2,4-dinitrotoluene 3.9118551238
MESH:D017449 Dermatitis, Allergic Contact nickel sulfate 3.5716823706 16780908 11298694
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.3818249437
MESH:D003921 Diabetes Mellitus, Experimental Quercetin 3.6419496084
MESH:D003924 Diabetes Mellitus, Type 2 Ascorbic Acid 7.0316506275
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 7.0320387270
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 7.0317107852
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 25.3618551238 21346803
MESH:D056486 Drug-Induced Liver Injury 4-amino-2,6-dinitrotoluene 25.3621346803
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 25.367179309 15968718 6884620 19085960 11566570 10915739 10092053 9327722 2869522 15998439 15027814 3786805 19336974 4309450 7440962 7120509 16227642 3732212 17522070 21278145 16177239 6623471
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 25.3619107877
MESH:D056486 Drug-Induced Liver Injury Ethanol 25.3611566570
MESH:D056486 Drug-Induced Liver Injury Selenium 25.3615131321
MESH:D056486 Drug-Induced Liver Injury sodium arsenate 25.3618186108
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 25.3620420201
MESH:D056486 Drug-Induced Liver Injury Valproic Acid 25.3619641884 1733752
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.6811462148
MESH:D004421 Dystonia Valproic Acid 3.941851702
MESH:C538011 Eales disease Ascorbic Acid 12.729068938
MESH:C538011 Eales disease Vitamin E 12.729068938
MESH:D004487 Edema pirinixic acid 6.2012083418
MESH:D004487 Edema Tetrachlorodibenzodioxin 6.2011000095 12711302
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.8018230668 15322242 16714409
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 2.929294722 10568697
MESH:D004831 Epilepsies, Myoclonic Valproic Acid 4.0417275665 3659116
MESH:D004828 Epilepsies, Partial Valproic Acid 3.813922381 16628512
MESH:D004827 Epilepsy Valproic Acid 2.8820417680 18234410
MESH:D004832 Epilepsy, Absence Valproic Acid 3.496426943 7562514 6254150
MESH:D017029 Epilepsy, Complex Partial Valproic Acid 4.197750514
MESH:D004830 Epilepsy, Tonic-Clonic Valproic Acid 3.963659116
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 5.0116302075
MESH:D004938 Esophageal Neoplasms Ethanol 4.7916704527
MESH:D004938 Esophageal Neoplasms nitrosobenzylmethylamine 4.7916704527 16510608 15547721 15264214 15623463 16805852 15547733 15878914 15150132
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 2.9311564622
MESH:D005234 Fatty Liver Carbon Tetrachloride 35.4517595544 16239168 12795759 12631006 15959796 16045604 19224547 61145
MESH:D005234 Fatty Liver Cyclosporine 35.4519224547
MESH:D005234 Fatty Liver Diethylnitrosamine 35.4520387270 21071580
MESH:D005234 Fatty Liver Ethanol 35.4518620774 19236843 16409862
MESH:D005234 Fatty Liver Fish Oils 35.4518620774
MESH:D005234 Fatty Liver pirinixic acid 35.4520131406 19236843
MESH:D005234 Fatty Liver Valproic Acid 35.4514986274 19224547
MESH:D005235 Fatty Liver, Alcoholic Ethanol 5.5617920746
MESH:D005310 Fetal Alcohol Syndrome Ethanol 5.1916946407 15513904 15451040 10194807
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.3511858732
MESH:D005315 Fetal Diseases Valproic Acid 4.7816575769
MESH:D005317 Fetal Growth Retardation Valproic Acid 4.028888407 18558336
MESH:D005355 Fibrosis Carbon Tetrachloride 20.2618705752
MESH:D005355 Fibrosis Cyclosporine 20.2612639820 12168785
MESH:D005355 Fibrosis Quercetin 20.2619474275
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 20.2620067830
MESH:D005756 Gastritis Ethanol 4.5915046732
MESH:D005833 Genital Neoplasms, Female sodium arsenite 4.5716452187
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.118708960
MESH:D005909 Glioblastoma Quercetin 3.3219804834
MESH:D005910 Glioma Quercetin 3.0117643826
MESH:D018149 Glucose Intolerance sodium arsenate 4.9719446573
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.4910696789
MESH:D006330 Heart Defects, Congenital Ascorbic Acid 10.9216080930
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 10.9211294989 10048152
MESH:D006330 Heart Defects, Congenital Vitamin E 10.9216080930
MESH:D006333 Heart Failure pirinixic acid 6.7320558911
MESH:D006333 Heart Failure Selenium 6.7317162251
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.3115720958
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.2311000095
MESH:D006505 Hepatitis Carbon Tetrachloride 3.4919900420 19110552
MESH:D006529 Hepatomegaly pirinixic acid 7.9018467677 16221962 19772884 19176532
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 7.9012621046 16120746 15340226
MESH:D006548 Hernia, Diaphragmatic Ascorbic Acid 6.0016863852 16490937
MESH:D006548 Hernia, Diaphragmatic Vitamin E 6.0016863852 16490937
MESH:D006689 Hodgkin Disease sodium arsenite 3.0612676792
MESH:D019584 Hot Flashes Vitamin E 3.8714716179
MESH:D006849 Hydrocephalus Valproic Acid 4.7617688650
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.9415340226 16959395 8697196 16354765 18606429
MESH:D006930 Hyperalgesia Ethanol 3.6318783367
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 4.4216899240
MESH:D006943 Hyperglycemia pirinixic acid 8.9120558911
MESH:D006943 Hyperglycemia Quercetin 8.9118262572 11834736
MESH:D006949 Hyperlipidemias Fish Oils 4.6515752949
MESH:D006968 Hypersensitivity, Delayed Fish Oils 5.4011484837
MESH:D006973 Hypertension Cyclosporine 8.3410903974
MESH:D006973 Hypertension Quercetin 8.3418356687
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 8.3418850075 18670907
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 3.9815338365
MESH:D007248 Infertility, Male sodium arsenite 2.9215346721 12646999
MESH:D007249 Inflammation Diethylnitrosamine 4.7118785209
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 4.7112200463 12878042
MESH:D007251 Influenza, Human Quercetin 18.0116624496
MESH:D007251 Influenza, Human Selenium 18.0116624496
MESH:D007251 Influenza, Human Vitamin E 18.0116624496
MESH:D007333 Insulin Resistance pirinixic acid 2.5616306350
MESH:D007569 Jaw Abnormalities Ethanol 9.7815513904
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 9.7816580747
MESH:D007627 Keloid Quercetin 4.8517086741
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.3415604871
MESH:D007674 Kidney Diseases Cyclosporine 13.958314463 10903974 18776723
MESH:D007674 Kidney Diseases Quercetin 13.9516962696
MESH:D007674 Kidney Diseases sodium arsenite 13.9520008137
MESH:D007674 Kidney Diseases Vitamin E 13.9512488133
MESH:D007676 Kidney Failure, Chronic Selenium 3.7816518626
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 6.9716705839
MESH:D007680 Kidney Neoplasms Cyclosporine 6.9712371664
MESH:D007859 Learning Disorders Ethanol 4.1015451040
MESH:D007938 Leukemia Quercetin 3.1017468513
MESH:D015470 Leukemia, Myeloid, Acute Valproic Acid 2.1317596541 16294345
MESH:D017880 Limb Deformities, Congenital Ethanol 3.7317676605
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 10.7416943688 21278145 16221502 17174718 11408273 11903743 17334410 16239168 17157831
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 10.7418522880 18407596 20032147 19638242 18665156
MESH:D008103 Liver Cirrhosis Ethanol 10.7415289165
MESH:D008104 Liver Cirrhosis, Alcoholic Ethanol 4.9918295389
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 8.5718210741 12632512 15370692 16011737 14716496 18420326 12445418 12667390 17481882 17525996 14748882 12586293 17823541 15996030 16136751 18418968 18054572 11481614 15893842 18395095 12389079 12609069 15730626 15876570 14620537 18166357 18472332 12445421 12632514 17640975 12546737 20821823 15673190 15123356 16015684 18376398 18006644 16192424 17922224 17766677 15925388 18429990 17805973 17631135 17565644 15362042 18412020 18263696 17708605 14716833 18277467 15959796 17557913 12741479 16248980 18251166 15931870 18481824 12898905 16097048 18472094 12958196 18317297 17761835 18395914 17944888 15052691 17900296 15338365 18279442 14512876 14724832 17698563 18339082 16116963 17721639 16638106 17714472 15650968 10355542 12649538 16033810 17869086 18156304 12666154 15818738 18187930 16027843 13678700 18205269 18705752 15057751 17976157
MESH:D008106 Liver Cirrhosis, Experimental Ethanol 8.5718166357
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 8.5715474484
MESH:D008106 Liver Cirrhosis, Experimental Quercetin 8.5712741479
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 8.5712878042
MESH:D008106 Liver Cirrhosis, Experimental Vitamin E 8.5716169303
MESH:D008107 Liver Diseases Carbon Tetrachloride 3.9816246199 16964402 15830285 15720792 17285989
MESH:D008107 Liver Diseases Diethylnitrosamine 3.9817034775
MESH:D008108 Liver Diseases, Alcoholic Ethanol 4.5417207112 17347304
MESH:D017093 Liver Failure Carbon Tetrachloride 4.0515123358
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 3.5916899240 14706259
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 17.4519294768
MESH:D008113 Liver Neoplasms Diethylnitrosamine 17.4518978307 9163691 19833225 20492335 20118626 20137499 19255062 19638242 19850985 10737359 19642983 19812893 20434301 12771043 19551842 19256749 19294768 21278145 2422723 18644402 21167192 20405173 19073162 15175105 19996281 12112319 19427195 20452335 19090486 18754104 16942905 19426721 20101389 19254457 21047994 19690152 21071580 19499222 20583210 15885732 18648771 2862719 18977376 20501860
MESH:D008113 Liver Neoplasms pirinixic acid 17.4520007298 16377806 15890375
MESH:D008113 Liver Neoplasms Quercetin 17.4518980244
MESH:D008113 Liver Neoplasms sodium arsenite 17.4515276417 16712894
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 17.4516984957
MESH:D008114 Liver Neoplasms, Experimental Ascorbic Acid 17.9418544905
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 17.9412014681 15583823
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 17.9417174075 18079962 17854601 18253720 2563599 16267830 18282651 17942915 16842330 18544905 18093689 19009564 19004024 18775883 9362446 19539802 19126423 18164116 18308698 3124819 19519916 21159647
MESH:D008114 Liver Neoplasms, Experimental Quercetin 17.9419519916
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 17.9412151625
MESH:D008171 Lung Diseases Ascorbic Acid 12.0216863852
MESH:D008171 Lung Diseases sodium arsenite 12.0219095001
MESH:D008171 Lung Diseases Vitamin E 12.0216863852
MESH:D017563 Lung Diseases, Interstitial Valproic Acid 4.1617228818
MESH:D008175 Lung Neoplasms Ascorbic Acid 10.5116401635
MESH:D008175 Lung Neoplasms Diethylnitrosamine 10.516695378 21163286 20512841 20970405
MESH:D008175 Lung Neoplasms Quercetin 10.5116280456
MESH:D008175 Lung Neoplasms sodium arsenite 10.5115276417 17077188 16712894 19931552 17306315
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 10.5111884234 19555203
MESH:D008175 Lung Neoplasms tipifarnib 10.5116885199
MESH:D008175 Lung Neoplasms Vitamin E 10.5111062179
MESH:D008325 Mammary Neoplasms, Experimental Selenium 6.4415318939
MESH:D008325 Mammary Neoplasms, Experimental tipifarnib 6.4416648579
MESH:D008545 Melanoma sodium arsenite 2.0216487513 19082730
MESH:D008569 Memory Disorders Ethanol 4.0818411066 15451040
MESH:D008654 Mesothelioma Selenium 2.7515107826
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.6816801185
MESH:D008881 Migraine Disorders Valproic Acid 3.1118803445 18765137
MESH:D009135 Muscular Diseases pirinixic acid 3.4016239165
MESH:D009139 Musculoskeletal Abnormalities sodium arsenate 10.3418186108
MESH:D009139 Musculoskeletal Abnormalities Valproic Acid 10.348888407
MESH:D009190 Myelodysplastic Syndromes Valproic Acid 3.0917596541
MESH:D009203 Myocardial Infarction pirinixic acid 5.5819151258
MESH:D009203 Myocardial Infarction Quercetin 5.5819595682
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 2.9312213967
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 8.1516411023
MESH:D015428 Myocardial Reperfusion Injury Quercetin 8.1519207477
MESH:D009336 Necrosis 2,4-dinitrotoluene 3.7518551238
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 2.529029167 3581430
MESH:D009369 Neoplasms pirinixic acid 7.9717405874
MESH:D009369 Neoplasms Quercetin 7.9715185748
MESH:D009369 Neoplasms sodium arsenite 7.9711559025
MESH:D009374 Neoplasms, Experimental sodium arsenite 3.5620056578
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.3417954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.1919348381 18481113
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 3.1114600291
MESH:D009436 Neural Tube Defects sodium arsenate 11.8618186108 19446573 10525206 11749123
MESH:D009436 Neural Tube Defects sodium arsenite 11.8612854658
MESH:D009436 Neural Tube Defects Valproic Acid 11.868888407 16359493
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 3.2520387270
MESH:D020078 Neurogenic Inflammation Quercetin 4.2617929310
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 5.0120387270
MESH:D009765 Obesity Ascorbic Acid 4.6617217161
MESH:D009765 Obesity pirinixic acid 4.6620558911
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 8.8016049721 12819281
MESH:D009784 Occupational Diseases 4-amino-2,6-dinitrotoluene 8.8014694615
MESH:D015663 Osteoporosis, Postmenopausal Quercetin 4.1119495926
MESH:D010051 Ovarian Neoplasms Quercetin 4.9119005980
MESH:D010051 Ovarian Neoplasms sodium arsenite 4.9117306315 15276417
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 8.5016540662
MESH:D010190 Pancreatic Neoplasms Ethanol 8.5012384795
MESH:D010190 Pancreatic Neoplasms Quercetin 8.5016965848
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.1412520081
MESH:D010954 Plasmacytoma Selenium 4.7815087411
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.4518163543
MESH:D011230 Precancerous Conditions Cyclosporine 14.7712371664
MESH:D011230 Precancerous Conditions Diethylnitrosamine 14.772563599
MESH:D011230 Precancerous Conditions Quercetin 14.7719056647
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 9.1011896295 11118676 11222880 11399792
MESH:D011297 Prenatal Exposure Delayed Effects Valproic Acid 9.1020603192
MESH:D011471 Prostatic Neoplasms Quercetin 2.6717292933 14715546
MESH:D011471 Prostatic Neoplasms sodium arsenite 2.6716039940
MESH:D011471 Prostatic Neoplasms Vitamin E 2.6715084515
MESH:D019310 Pseudolymphoma Valproic Acid 4.4411422049 12752131
MESH:D011565 Psoriasis Cyclosporine 2.1916882103
MESH:D011657 Pulmonary Eosinophilia Ascorbic Acid 5.2314606601
MESH:D015427 Reperfusion Injury pirinixic acid 2.3319058328
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.7318990726
MESH:D012174 Retinitis Pigmentosa Ascorbic Acid 3.2816849425
MESH:D012208 Rhabdomyosarcoma Valproic Acid 4.0719155313
MESH:D012554 Schistosomiasis japonica Quercetin 5.4416862918
MESH:D012559 Schizophrenia Valproic Acid 2.0519110320 15737665
MESH:D012640 Seizures 2,4-dinitrotoluene 9.4718551238
MESH:D012640 Seizures Ethanol 9.479754883
MESH:D012640 Seizures Valproic Acid 9.4711044598 11738929 14763951 15475178 3137016 1511512 16876388 17978042
MESH:D012871 Skin Diseases Ascorbic Acid 5.1218709164
MESH:D012871 Skin Diseases Vitamin E 5.1218709164
MESH:D012878 Skin Neoplasms sodium arsenite 5.4219524636 18572023
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 5.4216192470
MESH:D016135 Spinal Dysraphism sodium arsenite 9.2612854658
MESH:D016135 Spinal Dysraphism Valproic Acid 9.2619490988
MESH:D013226 Status Epilepticus Valproic Acid 4.4412833885
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 3.4418456281
MESH:D013274 Stomach Neoplasms Ethanol 3.4418456281
MESH:D013274 Stomach Neoplasms nitrosobenzylmethylamine 3.4417575124 12958204
MESH:D013276 Stomach Ulcer Ascorbic Acid 7.3618726076
MESH:D013276 Stomach Ulcer Ethanol 7.369211565 16755016 17189318 11906479 9562338 17918041
MESH:D020521 Stroke Ascorbic Acid 8.5916517955 16403987
MESH:D020521 Stroke Vitamin E 8.5916517955
MESH:D013375 Substance Withdrawal Syndrome Ethanol 4.169754883
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.8012697716
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 2.907505956
MESH:D014178 Translocation, Genetic Valproic Acid 5.1317262798
MESH:D020194 Unverricht-Lundborg Syndrome Valproic Acid 4.413119515
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 8.1316049721
MESH:D001749 Urinary Bladder Neoplasms Quercetin 8.1316720314
MESH:D001749 Urinary Bladder Neoplasms sodium arsenite 8.1316712894 16452187 17306315 11723127
MESH:D014564 Urogenital Abnormalities Valproic Acid 4.538888407
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 4.2110091137
MESH:D002583 Uterine Cervical Neoplasms sodium arsenite 3.6711813266
MESH:D014605 Uveitis Cyclosporine 3.881336536
MESH:D014652 Vascular Diseases sodium arsenite 4.3217056641
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.4912125929
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.1415886252
MESH:D014985 Xerophthalmia Cyclosporine 4.3417120751
No data
Pharmacogenomics Knowledge Base Top
Drug Bank Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved