AutismKB 2.0

Annotation Detail for FAM107A


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Basic Information Top
Gene Symbol:FAM107A ( DRR1,FLJ30158,FLJ45473,TU3A )
Gene Full Name: family with sequence similarity 107, member A
Band: 3p14.3-p14.2
Quick LinksEntrez ID:11170; OMIM: 608295; Uniprot ID:F107A_HUMAN; ENSEMBL ID: ENSG00000168309; HGNC ID: 30827
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1766Renal Cell cancer
1934Cancer
No data
No data
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D001151 Arsenic Arsenic results in decreased expression of FAM107A mRNAdecreases expression 19654921
C006780 bisphenol A bisphenol A results in decreased expression of FAM107A mRNAdecreases expression 19371625
D004054 Diethylstilbestrol Diethylstilbestrol results in decreased expression of FAM107A mRNAdecreases expression 19371625
D015025 Zearalenone Zearalenone results in decreased expression of FAM107A mRNAdecreases expression 19371625
D019833 Genistein Genistein results in decreased expression of FAM107A mRNAdecreases expression 19371625
C008493 methylselenic acid methylselenic acid results in increased expression of FAM107A mRNAincreases expression 18548127
C016340 o,p'-DDT o,p'-DDT results in decreased expression of FAM107A mRNAdecreases expression 19371625
D011374 Progesterone Progesterone results in increased expression of FAM107A mRNAincreases expression 17404688
C059514 resveratrol resveratrol results in decreased expression of FAM107A mRNAdecreases expression 19371625
D012643 Selenium Selenium results in increased expression of FAM107A mRNAincreases expression 19244175
D014810 Vitamin E Vitamin E results in increased expression of FAM107A mRNAincreases expression 19244175
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D058186 Acute Kidney Injury resveratrol 3.9916538975
MESH:D000230 Adenocarcinoma Genistein 2.5111473722
MESH:D000236 Adenoma resveratrol 3.3915688382
MESH:D018246 Adrenocortical Adenoma Arsenic 5.4317306315
MESH:D000544 Alzheimer Disease resveratrol 2.5916183991 16162502
MESH:D000686 Amyloidosis Diethylstilbestrol 4.6415469931
MESH:D020261 Arsenic Poisoning Arsenic 2.9016835338 16251483 12569548 18414634
MESH:D001169 Arthritis, Experimental resveratrol 3.5817115116
MESH:D050197 Atherosclerosis Arsenic 7.1612928151 19371607
MESH:D050197 Atherosclerosis resveratrol 7.1616873680 17967414
MESH:D001862 Bone Resorption bisphenol A 4.0011985600
MESH:D020201 Brain Hemorrhage, Traumatic Progesterone 5.5617868700
MESH:D001930 Brain Injuries Progesterone 4.4315665606 15380490 15845082
MESH:D002545 Brain Ischemia resveratrol 4.4817600658
MESH:D001943 Breast Neoplasms bisphenol A 2.4017123778
MESH:D001943 Breast Neoplasms Diethylstilbestrol 2.4015324884 17129689
MESH:D001943 Breast Neoplasms Genistein 2.4016541309 16873071 17200150
MESH:D001943 Breast Neoplasms Progesterone 2.4017614352 15562024 16175315
MESH:D001943 Breast Neoplasms resveratrol 2.4016393696 17534123 17651959
MESH:D002252 Carbon Tetrachloride Poisoning Vitamin E 4.1116050911
MESH:D002280 Carcinoma, Basal Cell Arsenic 3.6615504454 17687452
MESH:D006528 Carcinoma, Hepatocellular Arsenic 6.8216507464 17306315
MESH:D006528 Carcinoma, Hepatocellular Diethylstilbestrol 6.8216924424 15948411
MESH:D006528 Carcinoma, Hepatocellular Genistein 6.8216924424
MESH:D006528 Carcinoma, Hepatocellular resveratrol 6.8216227395 19321006
MESH:D002278 Carcinoma in Situ bisphenol A 5.1817123778
MESH:D018827 Carcinoma, Lewis Lung resveratrol 4.7816675471
MESH:D002294 Carcinoma, Squamous Cell Arsenic 5.0817687452 18922899 15504454
MESH:D002294 Carcinoma, Squamous Cell resveratrol 5.0816227395
MESH:D002295 Carcinoma, Transitional Cell Arsenic 4.2118640142
MESH:D002318 Cardiovascular Diseases Arsenic 12.8115738583 19152805 17938729
MESH:D002318 Cardiovascular Diseases Genistein 12.8116332659
MESH:D002318 Cardiovascular Diseases resveratrol 12.8115458977
MESH:D002340 Carotid Artery Diseases Arsenic 4.4316973168 18022660
MESH:D003092 Colitis resveratrol 10.2516474422
MESH:D003092 Colitis Selenium 10.2517936198
MESH:D003110 Colonic Neoplasms Genistein 4.0117182828
MESH:D003110 Colonic Neoplasms resveratrol 4.0116338953
MESH:D015179 Colorectal Neoplasms resveratrol 2.2216550006
MESH:D003327 Coronary Disease resveratrol 3.8416507316
MESH:D019465 Craniofacial Abnormalities Vitamin E 1.9219769572
MESH:D003456 Cryptorchidism Diethylstilbestrol 4.7212952375 16002989
MESH:D003921 Diabetes Mellitus, Experimental resveratrol 3.8916873680
MESH:D003924 Diabetes Mellitus, Type 2 Genistein 2.5116647724
MESH:D003928 Diabetic Nephropathies resveratrol 4.0916286809
MESH:D003929 Diabetic Neuropathies Progesterone 4.6717187935
MESH:D056486 Drug-Induced Liver Injury Selenium 2.2115131321
MESH:C538011 Eales disease Vitamin E 4.929068938
MESH:D004487 Edema resveratrol 3.508985016
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Progesterone 9.8917692515
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental resveratrol 9.8917872969
MESH:D004714 Endometrial Hyperplasia Diethylstilbestrol 12.5516402032
MESH:D004714 Endometrial Hyperplasia Genistein 12.5516402032
MESH:D016889 Endometrial Neoplasms Diethylstilbestrol 7.9816804899 15700306
MESH:D016889 Endometrial Neoplasms Genistein 7.9811473722
MESH:D004715 Endometriosis Progesterone 3.9016134523
MESH:D020345 Enterocolitis, Necrotizing resveratrol 5.0217923197
MESH:D052776 Female Urogenital Diseases Diethylstilbestrol 3.7315751030 16513791 16534752 16611131 16002989
MESH:D005534 Foot Diseases Arsenic 5.786392382
MESH:D005833 Genital Neoplasms, Female Diethylstilbestrol 5.1416452187
MESH:D005909 Glioblastoma Genistein 3.3416598420
MESH:D005910 Glioma marker/mechanism 16865689
MESH:D006330 Heart Defects, Congenital Vitamin E 3.0516080930
MESH:D006333 Heart Failure Selenium 3.1517162251
MESH:D006548 Hernia, Diaphragmatic Vitamin E 2.7416490937 16863852
MESH:D006561 Herpes Simplex resveratrol 4.3716876885
MESH:D019584 Hot Flashes Vitamin E 4.1914716179
MESH:D006937 Hypercholesterolemia resveratrol 4.1417188708
MESH:D017488 Hyperkeratosis, Epidermolytic Arsenic 4.5917050553
MESH:D006949 Hyperlipidemias resveratrol 4.1816873680
MESH:D006965 Hyperplasia Diethylstilbestrol 4.6112960047 14722030
MESH:D006973 Hypertension Arsenic 2.9116076760 9931084 11953799
MESH:D017379 Hypertrophy, Left Ventricular resveratrol 4.4317488730
MESH:D006987 Hypesthesia Arsenic 5.7816093927
MESH:D007021 Hypospadias Diethylstilbestrol 4.7516002989
MESH:D020244 Infarction, Middle Cerebral Artery Progesterone 12.0815869954
MESH:D020244 Infarction, Middle Cerebral Artery resveratrol 12.0817600658
MESH:D007246 Infertility Diethylstilbestrol 4.5215036965
MESH:D007249 Inflammation Progesterone 5.5715869954
MESH:D007249 Inflammation resveratrol 5.5716366677
MESH:D007251 Influenza, Human resveratrol 19.9616624496
MESH:D007251 Influenza, Human Selenium 19.9616624496
MESH:D007251 Influenza, Human Vitamin E 19.9616624496
MESH:D007333 Insulin Resistance bisphenol A 3.3816393666
MESH:D007642 Keratosis Arsenic 5.1812749816 16930632
MESH:D007674 Kidney Diseases Vitamin E 2.8812488133
MESH:D007676 Kidney Failure, Chronic Selenium 4.0216518626
MESH:D007680 Kidney Neoplasms Diethylstilbestrol 3.5815003126 14681315 16762066
MESH:D007859 Learning Disorders Diethylstilbestrol 4.2417184923
MESH:D007938 Leukemia Genistein 3.0918980019 17468513
MESH:D015473 Leukemia, Promyelocytic, Acute Arsenic 8.2117339181
MESH:D015473 Leukemia, Promyelocytic, Acute resveratrol 8.2116087638
MESH:D008106 Liver Cirrhosis, Experimental Genistein 2.6817823541
MESH:D008106 Liver Cirrhosis, Experimental Vitamin E 2.6816169303
MESH:D008107 Liver Diseases Arsenic 2.5711134558
MESH:D008113 Liver Neoplasms Arsenic 7.9216368122
MESH:D008113 Liver Neoplasms Diethylstilbestrol 7.9216712894 15890375
MESH:D008113 Liver Neoplasms resveratrol 7.9219812893 20405173 19073162 19321006
MESH:D008171 Lung Diseases Vitamin E 3.2716863852
MESH:D008175 Lung Neoplasms Arsenic 2.7017976673 19168569 17306315
MESH:D008175 Lung Neoplasms Vitamin E 2.7011062179
MESH:D008181 Lupus Nephritis Diethylstilbestrol 5.3415166399
MESH:D008223 Lymphoma Diethylstilbestrol 3.5715700306
MESH:D016393 Lymphoma, B-Cell resveratrol 4.4517088997
MESH:D008228 Lymphoma, Non-Hodgkin resveratrol 3.9914749477
MESH:D052801 Male Urogenital Diseases Diethylstilbestrol 5.7316002989
MESH:D015674 Mammary Neoplasms, Animal resveratrol 4.4415688416
MESH:D008325 Mammary Neoplasms, Experimental Genistein 15.0512929590 14578162
MESH:D008325 Mammary Neoplasms, Experimental Progesterone 15.0511408345 17203775
MESH:D008325 Mammary Neoplasms, Experimental resveratrol 15.058985016 11606380
MESH:D008325 Mammary Neoplasms, Experimental Selenium 15.0515318939
MESH:D008545 Melanoma resveratrol 2.3817992120
MESH:D008654 Mesothelioma Selenium 2.8415107826
MESH:D008659 Metabolic Diseases resveratrol 4.5217112576
MESH:D009101 Multiple Myeloma resveratrol 3.5617164350 17935668 16267019 17049120 14749477 16490592
MESH:D009134 Muscular Atrophy, Spinal resveratrol 5.0617962980
MESH:D009203 Myocardial Infarction Genistein 6.1817141266
MESH:D009203 Myocardial Infarction resveratrol 6.1816456233 16525036 16317513 17188708 17015251 17125593
MESH:D017202 Myocardial Ischemia Arsenic 9.7415371236
MESH:D017202 Myocardial Ischemia resveratrol 9.7417125593 17015251
MESH:D015428 Myocardial Reperfusion Injury Genistein 3.7717141266
MESH:D009205 Myocarditis resveratrol 4.9517322642
MESH:D009369 Neoplasms Diethylstilbestrol 2.8215313581
MESH:D009374 Neoplasms, Experimental resveratrol 4.178985016
MESH:D009421 Nervous System Malformations bisphenol A 17.5111399458 16427766
MESH:D009421 Nervous System Malformations Diethylstilbestrol 17.5111399458
MESH:D009421 Nervous System Malformations Genistein 17.5116427766
MESH:D009436 Neural Tube Defects Arsenic 3.5416620997
MESH:D019636 Neurodegenerative Diseases resveratrol 3.9217652729
MESH:D020078 Neurogenic Inflammation Arsenic 11.2117056641
MESH:D020078 Neurogenic Inflammation resveratrol 11.2117929310
MESH:D010024 Osteoporosis Genistein 3.3319401787
MESH:D015663 Osteoporosis, Postmenopausal Genistein 10.6616169203
MESH:D015663 Osteoporosis, Postmenopausal resveratrol 10.6617513867
MESH:D010049 Ovarian Diseases bisphenol A 5.1811985600
MESH:D010051 Ovarian Neoplasms Arsenic 8.2217306315
MESH:D010051 Ovarian Neoplasms Genistein 8.2219005980
MESH:D010051 Ovarian Neoplasms Progesterone 8.2216525653 17393432
MESH:D010523 Peripheral Nervous System Diseases Arsenic 4.3416093927
MESH:D016491 Peripheral Vascular Diseases Arsenic 5.1816905509 6392382 15371236
MESH:D010900 Pituitary Diseases Diethylstilbestrol 5.3914722030
MESH:D010911 Pituitary Neoplasms Diethylstilbestrol 4.8515687265 16977796
MESH:D010954 Plasmacytoma Selenium 5.1115087411
MESH:D011297 Prenatal Exposure Delayed Effects bisphenol A 17.6010548101
MESH:D011297 Prenatal Exposure Delayed Effects Diethylstilbestrol 17.6017184923
MESH:D011297 Prenatal Exposure Delayed Effects resveratrol 17.6016679765
MESH:D019048 Prostatic Intraepithelial Neoplasia bisphenol A 4.3520887781
MESH:D011471 Prostatic Neoplasms Arsenic 2.1316140617
MESH:D011471 Prostatic Neoplasms bisphenol A 2.1316740699
MESH:D011471 Prostatic Neoplasms Diethylstilbestrol 2.1317136230 15846301 15046698
MESH:D011471 Prostatic Neoplasms Genistein 2.1315378649 15256057 16925846
MESH:D011471 Prostatic Neoplasms methylselenic acid 2.1316205645
MESH:D011471 Prostatic Neoplasms resveratrol 2.1317804756 17718901 17675339 15767336 17636462 16731767
MESH:D011471 Prostatic Neoplasms Vitamin E 2.1315084515
MESH:D011507 Proteinuria Arsenic 4.1521343184
MESH:D011629 Puberty, Precocious bisphenol A 4.9810548101
MESH:D051436 Renal Insufficiency, Chronic resveratrol 5.8016325855
MESH:D015427 Reperfusion Injury resveratrol 3.3316314181 17058453 17520802 16317513 15827377
MESH:D012468 Salivary Gland Neoplasms Progesterone 2.9018045962
MESH:D012871 Skin Diseases Arsenic 5.1519834688 15952646 17938729 16353154 6392382 17548696 18709164 16702368 16759981 17453740 17050553
MESH:D012871 Skin Diseases Vitamin E 5.1518709164
MESH:D012878 Skin Neoplasms Arsenic 6.2717976673 17050553 17029826 16251483 15504454 19538983
MESH:D012878 Skin Neoplasms resveratrol 6.278985016 15837718
MESH:D013088 Spermatocele Diethylstilbestrol 4.9316002989 16709447
MESH:D013119 Spinal Cord Injuries Progesterone 4.4715862959 16503802
MESH:D020521 Stroke Vitamin E 3.6316517955
OMIM:601367 STROKE, ISCHEMIC resveratrol 4.6116321402
MESH:D019966 Substance-Related Disorders bisphenol A 4.1816684133 16045194
MESH:D014062 Tongue Neoplasms resveratrol 4.3416227395
MESH:D001749 Urinary Bladder Neoplasms Arsenic 5.5511144890 15987713 17976673 17306315 19322015 18640142 19429237
MESH:D001749 Urinary Bladder Neoplasms Diethylstilbestrol 5.5516712894 16452187 17306315
MESH:D002583 Uterine Cervical Neoplasms Diethylstilbestrol 10.1116175088
MESH:D002583 Uterine Cervical Neoplasms resveratrol 10.1117473185
MESH:D014591 Uterine Diseases bisphenol A 14.5614652134
MESH:D014591 Uterine Diseases Diethylstilbestrol 14.5614652134
MESH:D014594 Uterine Neoplasms Diethylstilbestrol 10.3315809267 16690809
MESH:D014594 Uterine Neoplasms resveratrol 10.3317044934
MESH:D014625 Vaginal Neoplasms Diethylstilbestrol 4.6116513791 16002989
MESH:D014652 Vascular Diseases Arsenic 4.9317056641
MESH:D018487 Ventricular Dysfunction, Left resveratrol 4.4817488730
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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