Annotation Detail for RASSF1
Basic Information Top
| Gene Symbol: | RASSF1 ( 123F2,NORE2A,RASSF1A,RDA32,REH3P21 ) |
|---|---|
| Gene Full Name: | Ras association (RalGDS/AF-6) domain family member 1 |
| Band: | 3p21.31 |
| Quick Links | Entrez ID:11186; OMIM: 605082; Uniprot ID:RASF1_HUMAN; ENSEMBL ID: ENSG00000068028; HGNC ID: 9882 |
| Relate to Another Database: | SFARIGene; denovo-db |
| Desease ID | Desease Name |
|---|---|
| Cancers | |
| Cancers of the urinary system and male genital organs | |
| H00014 | Non-small cell lung cancer |
| H00022 | Bladder cancer |
| Head and neck cancers | |
| Cancers of the lung and pleura | |
| H00054 | Nasopharyngeal cancer |
| Desease ID | Desease Name |
|---|---|
| 1856 | Obesity |
| 1934 | Cancer |
| 2044 | Pre-Eclampsia |
| 2052 | Infection |
| Desease Name |
|---|
| colorectal cancer |
| CANCER |
| esophageal cancer |
| breast cancer |
| lung cancer |
| head and neck cancer |
| No data |
| Desease Name |
|---|
| Lung cancer |
| Chemical ID | Chemical Name | Interaction | Interaction Action | Publication |
|---|---|---|---|---|
| C010914 | 2,4-diaminotoluene | 2,4-diaminotoluene results in increased expression of RASSF1 mRNA | increases expression | 20713471 |
| C016403 | 2,4-dinitrotoluene | 2,4-dinitrotoluene affects the expression of RASSF1 mRNA | affects expression | 21346803 |
| D000082 | Acetaminophen | Acetaminophen affects the expression of RASSF1 mRNA | affects expression | 17562736 |
| D001151 | Arsenic | Arsenic results in increased methylation of RASSF1 promoter | increases methylation | 15987713 |
| C006632 | arsenic trioxide | arsenic trioxide results in decreased methylation of RASSF1 gene | decreases methylation | 20079060 |
| C006632 | arsenic trioxide | arsenic trioxide results in increased expression of RASSF1 mRNA | increases expression | 20079060 |
| C006632 | arsenic trioxide | arsenic trioxide results in increased expression of RASSF1 protein | increases expression | 20079060 |
| D001194 | Asbestos | Asbestos results in increased methylation of RASSF1 promoter | increases methylation | 15911247 |
| D017638 | Asbestos, Crocidolite | Asbestos, Crocidolite affects the expression of RASSF1 mRNA | affects expression | 17331233 |
| D017638 | Asbestos, Crocidolite | Asbestos, Crocidolite results in increased expression of RASSF1 mRNA | increases expression | 18687144 |
| C095105 | bexarotene | bexarotene results in decreased expression of RASSF1 mRNA | decreases expression | 17849452 |
| D002087 | Butyrates | Butyrates promotes the reaction [decitabine results in decreased methylation of RASSF1 promoter] | decreases methylation|increases reaction | 18203293 |
| D002087 | Butyrates | Butyrates promotes the reaction [decitabine results in increased expression of RASSF1 mRNA] | increases expression|increases reaction | 18203293 |
| D002087 | Butyrates | Butyrates promotes the reaction [decitabine results in increased expression of RASSF1 protein] | increases expression|increases reaction | 18203293 |
| D016572 | Cyclosporine | Cyclosporine results in increased expression of RASSF1 mRNA | increases expression | 20106945 |
| C014347 | decitabine | Butyrates promotes the reaction [decitabine results in decreased methylation of RASSF1 promoter] | decreases methylation|increases reaction | 18203293 |
| C014347 | decitabine | Butyrates promotes the reaction [decitabine results in increased expression of RASSF1 mRNA] | increases expression|increases reaction | 18203293 |
| C014347 | decitabine | Butyrates promotes the reaction [decitabine results in increased expression of RASSF1 protein] | increases expression|increases reaction | 18203293 |
| C014347 | decitabine | decitabine affects the expression of RASSF1 mRNA | affects expression | 18320071 |
| C014347 | decitabine | decitabine affects the methylation of RASSF1 promoter | affects methylation | 17671114 17571247 17641842 17526942 |
| C014347 | decitabine | [decitabine co-treated with trichostatin A] affects the expression of RASSF1 protein | affects cotreatment|affects expression | 17019711 |
| C014347 | decitabine | [[decitabine co-treated with trichostatin A] affects the methylation of RASSF1 promoter] which affects the expression of RASSF1 mRNA | affects cotreatment|affects expression|affects methylation | 18819746 |
| C014347 | decitabine | decitabine results in decreased methylation of RASSF1 promoter | decreases methylation | 19172108 18203293 19440673 19442645 |
| C014347 | decitabine | decitabine results in increased expression of RASSF1 mRNA | increases expression | 19442645 19037991 18203293 19215824 19172108 19440673 |
| C014347 | decitabine | decitabine results in increased expression of RASSF1 protein | increases expression | 18203293 19172108 |
| D002945 | Cisplatin | RASSF1 protein results in increased susceptibility to Cisplatin | increases response to substance | 17444856 |
| D004052 | Diethylnitrosamine | [Diethylnitrosamine co-treated with Methylcholanthrene] results in decreased expression of RASSF1 protein | affects cotreatment|decreases expression | 20970405 |
| D004052 | Diethylnitrosamine | [Diethylnitrosamine co-treated with Methylcholanthrene] results in increased methylation of RASSF1 promoter | affects cotreatment|increases methylation | 20970405 |
| D004958 | Estradiol | Estradiol affects the expression of RASSF1 mRNA | affects expression | 15598610 |
| D004997 | Ethinyl Estradiol | Ethinyl Estradiol affects the expression of RASSF1 mRNA | affects expression | 17555576 |
| D004997 | Ethinyl Estradiol | Ethinyl Estradiol results in increased expression of RASSF1 mRNA | increases expression | 17942748 |
| D004997 | Ethinyl Estradiol | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of RASSF1 mRNA | affects cotreatment|increases expression | 17942748 |
| D006851 | Hydrochloric Acid | Hydrochloric Acid results in decreased expression of RASSF1 mRNA | decreases expression | 15046208 |
| D008748 | Methylcholanthrene | [Diethylnitrosamine co-treated with Methylcholanthrene] results in decreased expression of RASSF1 protein | affects cotreatment|decreases expression | 20970405 |
| D008748 | Methylcholanthrene | [Diethylnitrosamine co-treated with Methylcholanthrene] results in increased methylation of RASSF1 promoter | affects cotreatment|increases methylation | 20970405 |
| D016685 | Mitomycin | RASSF1 protein results in increased susceptibility to Mitomycin | increases response to substance | 17444856 |
| D012643 | Selenium | Selenium results in increased expression of RASSF1 mRNA | increases expression | 19244175 |
| C017947 | sodium arsenite | sodium arsenite results in increased expression of RASSF1 mRNA | increases expression | 12634122 |
| D013629 | Tamoxifen | Tamoxifen affects the expression of RASSF1 mRNA | affects expression | 17555576 |
| D013749 | Tetrachlorodibenzodioxin | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of RASSF1 mRNA | affects cotreatment|increases expression | 17942748 |
| C012589 | trichostatin A | [decitabine co-treated with trichostatin A] affects the expression of RASSF1 protein | affects cotreatment|affects expression | 17019711 |
| C012589 | trichostatin A | [[decitabine co-treated with trichostatin A] affects the methylation of RASSF1 promoter] which affects the expression of RASSF1 mRNA | affects cotreatment|affects expression|affects methylation | 18819746 |
| C017963 | vinyl carbamate | vinyl carbamate results in decreased expression of RASSF1 mRNA | decreases expression | 17849452 |
| D014810 | Vitamin E | Vitamin E results in increased expression of RASSF1 mRNA | increases expression | 19244175 |
| Disease ID | Disease Name | Direct Evidence | Inference Chemical Name | Inference Score | Publication |
|---|---|---|---|---|---|
| MESH:D000008 | Abdominal Neoplasms | Tamoxifen | 4.35 | 14745880 | |
| MESH:D000014 | Abnormalities, Drug-Induced | Tetrachlorodibenzodioxin | 2.66 | 15322242 14514962 11752688 | |
| MESH:D000138 | Acidosis | Hydrochloric Acid | 5.00 | 15920416 20872349 16144966 12771618 11574821 19262391 | |
| MESH:D000141 | Acidosis, Renal Tubular | Hydrochloric Acid | 5.58 | 17183249 | |
| MESH:D000142 | Acidosis, Respiratory | Hydrochloric Acid | 5.62 | 20597076 | |
| MESH:D000152 | Acne Vulgaris | Ethinyl Estradiol | 3.75 | 17505938 | |
| MESH:D058186 | Acute Kidney Injury | Cisplatin | 3.79 | 12690470 17670903 15814532 | |
| MESH:D055371 | Acute Lung Injury | Hydrochloric Acid | 4.60 | 11953099 19760209 16759491 19094174 19060228 15970105 11850527 | |
| MESH:D000230 | Adenocarcinoma | marker/mechanism | 15639718 | ||
| MESH:D000230 | Adenocarcinoma | arsenic trioxide | 13.05 | 19825857 11798837 | |
| MESH:D000230 | Adenocarcinoma | Cisplatin | 13.05 | 11798837 17638652 | |
| MESH:D000230 | Adenocarcinoma | Estradiol | 13.05 | 11473722 | |
| MESH:D000230 | Adenocarcinoma | Ethinyl Estradiol | 13.05 | 14692618 | |
| MESH:D000230 | Adenocarcinoma | vinyl carbamate | 13.05 | 16247444 17363558 | |
| MESH:D000236 | Adenoma | Diethylnitrosamine | 6.58 | 6695378 10737359 | |
| MESH:D000236 | Adenoma | Methylcholanthrene | 6.58 | 10545420 6695378 | |
| MESH:D018248 | Adenoma, Liver Cell | Diethylnitrosamine | 16.45 | 16434500 17162532 19061943 18056438 19052882 17620307 | |
| MESH:D018248 | Adenoma, Liver Cell | Tetrachlorodibenzodioxin | 16.45 | 16835633 | |
| MESH:D018248 | Adenoma, Liver Cell | vinyl carbamate | 16.45 | 12371669 | |
| MESH:D000310 | Adrenal Gland Neoplasms | sodium arsenite | 4.51 | 15276417 | |
| MESH:D018246 | Adrenocortical Adenoma | Arsenic | 13.15 | 17306315 | |
| MESH:D018246 | Adrenocortical Adenoma | sodium arsenite | 13.15 | 16712894 17306315 | |
| MESH:D000740 | Anemia | Tetrachlorodibenzodioxin | 2.78 | 11748828 | |
| MESH:D000799 | Angioedema | Acetaminophen | 3.65 | 10982225 | |
| MESH:D000860 | Anoxia | Hydrochloric Acid | 5.11 | 15090967 | |
| MESH:D020261 | Arsenic Poisoning | Arsenic | 2.81 | 18414634 12569548 16251483 16835338 | |
| MESH:D001161 | Arteriosclerosis | Ethinyl Estradiol | 3.28 | 11256880 | |
| MESH:D001169 | Arthritis, Experimental | Ethinyl Estradiol | 2.55 | 15885639 | |
| MESH:D050197 | Atherosclerosis | Arsenic | 10.60 | 12928151 19371607 | |
| MESH:D050197 | Atherosclerosis | Asbestos | 10.60 | 18795166 | |
| MESH:D050197 | Atherosclerosis | Methylcholanthrene | 10.60 | 11922910 | |
| MESH:D001321 | Autistic Disorder | Acetaminophen | 1.44 | 18445737 | |
| MESH:D001778 | Blood Coagulation Disorders | arsenic trioxide | 14.50 | 16206674 | |
| MESH:D001778 | Blood Coagulation Disorders | Hydrochloric Acid | 14.50 | 15920416 | |
| MESH:D001778 | Blood Coagulation Disorders | Tetrachlorodibenzodioxin | 14.50 | 12125929 | |
| MESH:D001836 | Body Weight Changes | Tetrachlorodibenzodioxin | 3.60 | 15340226 | |
| MESH:D001848 | Bone Diseases, Developmental | Tetrachlorodibenzodioxin | 2.64 | 15746008 | |
| MESH:D019046 | Bone Marrow Neoplasms | Cisplatin | 4.69 | 14601052 | |
| MESH:D001943 | Breast Neoplasms | 2,4-diaminotoluene | 5.65 | 11921183 | |
| MESH:D001943 | Breast Neoplasms | bexarotene | 5.65 | 16344269 16818667 | |
| MESH:D001943 | Breast Neoplasms | Cisplatin | 5.65 | 18382427 19526202 | |
| MESH:D001943 | Breast Neoplasms | decitabine | 5.65 | 19208741 18320071 | |
| MESH:D001943 | Breast Neoplasms | Diethylnitrosamine | 5.65 | 17474063 | |
| MESH:D001943 | Breast Neoplasms | Estradiol | 5.65 | 17261762 16675129 14630087 12948864 17018787 17289903 18497071 19861407 | |
| MESH:D001943 | Breast Neoplasms | Methylcholanthrene | 5.65 | 17474063 | |
| MESH:D001943 | Breast Neoplasms | Tamoxifen | 5.65 | 17440819 15668708 19142967 19189212 19059307 11161223 16202921 20859285 18984771 21152245 19487384 19155303 16818667 19189210 19244106 19221464 18425577 16873071 17049068 19115204 19066611 18629630 19103187 20544844 18351453 15565566 20005174 18815881 21138602 19200415 18997820 19084267 19410462 19011961 18855134 20135344 18821012 17893378 20390343 19288272 16273361 19289846 17261762 20065188 17242785 | |
| MESH:D001943 | Breast Neoplasms | Tetrachlorodibenzodioxin | 5.65 | 20435547 | |
| MESH:D016535 | Bronchial Hyperreactivity | Hydrochloric Acid | 4.44 | 12378975 | |
| MESH:D001986 | Bronchial Spasm | Hydrochloric Acid | 5.27 | 15578804 | |
| MESH:D002051 | Burkitt Lymphoma | arsenic trioxide | 4.15 | 11589617 | |
| MESH:D002181 | Candidiasis, Vulvovaginal | Estradiol | 4.27 | 16111702 | |
| MESH:D002252 | Carbon Tetrachloride Poisoning | Vitamin E | 3.74 | 16050911 | |
| MESH:D002277 | Carcinoma | Methylcholanthrene | 7.83 | 10545420 | |
| MESH:D002277 | Carcinoma | Tetrachlorodibenzodioxin | 7.83 | 16835633 | |
| MESH:D002280 | Carcinoma, Basal Cell | Arsenic | 3.49 | 17687452 15504454 | |
| MESH:D018270 | Carcinoma, Ductal, Breast | Tamoxifen | 4.32 | 19066611 | |
| MESH:D006528 | Carcinoma, Hepatocellular | 2,4-dinitrotoluene | 22.34 | 16705839 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Acetaminophen | 22.34 | 3084413 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Arsenic | 22.34 | 17306315 16507464 | |
| MESH:D006528 | Carcinoma, Hepatocellular | arsenic trioxide | 22.34 | 15553829 15073043 14691202 16217749 11135700 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Cisplatin | 22.34 | 17982673 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Diethylnitrosamine | 22.34 | 20514400 16698587 18785209 19919837 17055752 16935385 3084413 20214788 20084675 18971187 10672840 18691550 19539802 16830150 17978847 19418558 16807293 16569478 16288022 20101231 17173139 20512989 19394651 18665156 17761372 19383236 18210153 20007298 19171122 19107877 11831363 16540662 17428255 18494052 17138121 20432363 3581430 21159647 16328049 16681979 20727157 10737359 18506893 17162532 16878318 16779866 19335982 19208518 18788625 19822196 20935162 18978308 19052882 20524982 19519916 18056438 16502159 18393292 19701751 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Estradiol | 22.34 | 16924424 | |
| MESH:D006528 | Carcinoma, Hepatocellular | sodium arsenite | 22.34 | 16507464 17306315 15276417 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Tamoxifen | 22.34 | 16924424 | |
| MESH:D006528 | Carcinoma, Hepatocellular | vinyl carbamate | 22.34 | 12371669 | |
| MESH:D002289 | Carcinoma, Non-Small-Cell Lung | marker/mechanism | 18337602 | ||
| MESH:D002289 | Carcinoma, Non-Small-Cell Lung | bexarotene | 8.88 | 16247446 | |
| MESH:D002289 | Carcinoma, Non-Small-Cell Lung | Cisplatin | 8.88 | 12023789 16685392 | |
| MESH:D002289 | Carcinoma, Non-Small-Cell Lung | vinyl carbamate | 8.88 | 16247446 | |
| MESH:D002291 | Carcinoma, Papillary | arsenic trioxide | 4.68 | 19014326 | |
| MESH:D018288 | Carcinoma, Small Cell | arsenic trioxide | 3.95 | 12490120 | |
| MESH:D002294 | Carcinoma, Squamous Cell | Arsenic | 10.39 | 17687452 15504454 18922899 | |
| MESH:D002294 | Carcinoma, Squamous Cell | Cisplatin | 10.39 | 17066447 6189445 18337622 | |
| MESH:D002294 | Carcinoma, Squamous Cell | decitabine | 10.39 | 19215824 | |
| MESH:D002294 | Carcinoma, Squamous Cell | sodium arsenite | 10.39 | 18572023 | |
| MESH:D002295 | Carcinoma, Transitional Cell | Arsenic | 8.95 | 18640142 | |
| MESH:D002295 | Carcinoma, Transitional Cell | Tamoxifen | 8.95 | 17572228 | |
| MESH:D006332 | Cardiomegaly | Tetrachlorodibenzodioxin | 2.26 | 18850075 16120746 18670907 | |
| MESH:D002318 | Cardiovascular Diseases | Arsenic | 3.32 | 17938729 19152805 15738583 | |
| MESH:D002340 | Carotid Artery Diseases | Arsenic | 4.15 | 18022660 16973168 | |
| MESH:D002386 | Cataract | Acetaminophen | 2.47 | 10977129 | |
| MESH:D002471 | Cell Transformation, Neoplastic | Cyclosporine | 19.72 | 12371664 | |
| MESH:D002471 | Cell Transformation, Neoplastic | Diethylnitrosamine | 19.72 | 21159647 17174075 2727394 7505956 | |
| MESH:D002471 | Cell Transformation, Neoplastic | Estradiol | 19.72 | 18566989 | |
| MESH:D002471 | Cell Transformation, Neoplastic | Methylcholanthrene | 19.72 | 16192471 | |
| MESH:D002471 | Cell Transformation, Neoplastic | sodium arsenite | 19.72 | 19524636 20056578 | |
| MESH:D018281 | Cholangiocarcinoma | Diethylnitrosamine | 8.79 | 19052882 | |
| MESH:D018281 | Cholangiocarcinoma | Tetrachlorodibenzodioxin | 8.79 | 16835633 | |
| MESH:D002779 | Cholestasis | Cyclosporine | 7.31 | 19486331 | |
| MESH:D002779 | Cholestasis | Ethinyl Estradiol | 7.31 | 11677210 16919318 17110522 16105132 15861022 17681005 17333356 | |
| MESH:D002972 | Cleft Palate | Tetrachlorodibenzodioxin | 2.03 | 16354765 12621046 8697196 15340226 15668235 | |
| MESH:D003092 | Colitis | Selenium | 3.59 | 17936198 | |
| MESH:D003110 | Colonic Neoplasms | Butyrates | 4.06 | 15936596 | |
| MESH:D003110 | Colonic Neoplasms | decitabine | 4.06 | 17616700 | |
| MESH:D015179 | Colorectal Neoplasms | arsenic trioxide | 3.42 | 20501625 | |
| MESH:D015179 | Colorectal Neoplasms | Cisplatin | 3.42 | 15273666 | |
| MESH:D015179 | Colorectal Neoplasms | decitabine | 3.42 | 18981723 | |
| MESH:D000013 | Congenital Abnormalities | Tetrachlorodibenzodioxin | 2.90 | 17141729 14669216 | |
| MESH:D023903 | Coronary Restenosis | arsenic trioxide | 4.00 | 12609071 | |
| MESH:D019465 | Craniofacial Abnormalities | arsenic trioxide | 3.65 | 10525206 | |
| MESH:D019465 | Craniofacial Abnormalities | Tetrachlorodibenzodioxin | 3.65 | 10048152 20055451 15322242 | |
| MESH:D019465 | Craniofacial Abnormalities | Vitamin E | 3.65 | 19769572 | |
| MESH:D003490 | Cyanosis | 2,4-dinitrotoluene | 3.83 | 18551238 | |
| MESH:D003556 | Cystitis | Hydrochloric Acid | 5.27 | 12853844 19279288 20719367 12599022 | |
| MESH:D018856 | Cystitis, Interstitial | Hydrochloric Acid | 5.62 | 17714534 | |
| MESH:D016757 | Death, Sudden, Cardiac | arsenic trioxide | 3.92 | 15213294 | |
| MESH:D003711 | Demyelinating Diseases | Tamoxifen | 4.17 | 19031437 | |
| MESH:D003924 | Diabetes Mellitus, Type 2 | Diethylnitrosamine | 4.06 | 20387270 | |
| MESH:D003924 | Diabetes Mellitus, Type 2 | Tetrachlorodibenzodioxin | 4.06 | 17107852 | |
| MESH:D003928 | Diabetic Nephropathies | Estradiol | 8.30 | 19279558 | |
| MESH:D003928 | Diabetic Nephropathies | Tamoxifen | 8.30 | 19279558 | |
| MESH:D056486 | Drug-Induced Liver Injury | 2,4-dinitrotoluene | 11.38 | 21346803 18551238 | |
| MESH:D056486 | Drug-Induced Liver Injury | Acetaminophen | 11.38 | 19085960 10663392 16109766 12958197 19923254 11461765 11743745 17906064 2444490 11287661 16177239 14725611 11529661 16781746 18713872 16227642 15968718 10915739 19420014 19739265 12540782 12705907 17562736 12153990 16393943 11421492 16485898 18071297 16081117 17522070 12392966 11834606 14550746 14986274 10774834 19416960 15619225 19370779 12594235 11739529 19164858 | |
| MESH:D056486 | Drug-Induced Liver Injury | Diethylnitrosamine | 11.38 | 19107877 | |
| MESH:D056486 | Drug-Induced Liver Injury | Selenium | 11.38 | 15131321 | |
| MESH:D056486 | Drug-Induced Liver Injury | Tetrachlorodibenzodioxin | 11.38 | 20420201 | |
| MESH:D056487 | Drug-Induced Liver Injury, Chronic | Acetaminophen | 3.91 | 19426721 | |
| MESH:D004362 | Drug Toxicity | Cisplatin | 7.71 | 12649298 12231392 15033597 19839026 | |
| MESH:D004362 | Drug Toxicity | Tetrachlorodibenzodioxin | 7.71 | 11462148 | |
| MESH:C538011 | Eales disease | Vitamin E | 4.51 | 9068938 | |
| MESH:D004487 | Edema | Tetrachlorodibenzodioxin | 2.21 | 12711302 11000095 | |
| MESH:D004489 | Edema, Cardiac | Tetrachlorodibenzodioxin | 3.71 | 18230668 15322242 16714409 | |
| MESH:D004681 | Encephalomyelitis, Autoimmune, Experimental | Ethinyl Estradiol | 8.33 | 12538720 | |
| MESH:D004681 | Encephalomyelitis, Autoimmune, Experimental | Tamoxifen | 8.33 | 19031437 | |
| MESH:D004701 | Endocrine Gland Neoplasms | decitabine | 13.38 | 19294695 | |
| MESH:D004701 | Endocrine Gland Neoplasms | trichostatin A | 13.38 | 19294695 | |
| MESH:D016889 | Endometrial Neoplasms | Estradiol | 6.98 | 19148513 18566989 11473722 | |
| MESH:D016889 | Endometrial Neoplasms | Tamoxifen | 6.98 | 16202921 19155303 20544844 17893378 | |
| MESH:D004715 | Endometriosis | Tetrachlorodibenzodioxin | 2.86 | 10568697 9294722 | |
| MESH:D004931 | Esophageal Achalasia | Diethylnitrosamine | 4.92 | 16302075 | |
| MESH:D004935 | Esophageal Diseases | Hydrochloric Acid | 5.60 | 19566590 | |
| MESH:D004938 | Esophageal Neoplasms | arsenic trioxide | 4.55 | 12903497 | |
| MESH:D004938 | Esophageal Neoplasms | Cisplatin | 4.55 | 16481741 15464296 17638652 15173087 16785472 | |
| MESH:D004941 | Esophagitis | Hydrochloric Acid | 5.80 | 12928072 | |
| MESH:D004942 | Esophagitis, Peptic | Hydrochloric Acid | 5.82 | 20516732 14621274 11346197 | |
| MESH:D005124 | Eye Abnormalities | Tetrachlorodibenzodioxin | 2.87 | 11564622 | |
| MESH:D005234 | Fatty Liver | arsenic trioxide | 22.80 | 15073043 | |
| MESH:D005234 | Fatty Liver | Cyclosporine | 22.80 | 19224547 | |
| MESH:D005234 | Fatty Liver | Diethylnitrosamine | 22.80 | 20387270 21071580 | |
| MESH:D005234 | Fatty Liver | Ethinyl Estradiol | 22.80 | 15345470 | |
| MESH:D005234 | Fatty Liver | Tamoxifen | 22.80 | 19224547 14986274 | |
| MESH:D052776 | Female Urogenital Diseases | Tamoxifen | 3.12 | 16709447 | |
| MESH:D005313 | Fetal Death | Tetrachlorodibenzodioxin | 3.27 | 11858732 | |
| MESH:D018221 | Fibromatosis, Abdominal | Tamoxifen | 4.34 | 14745880 | |
| MESH:D018222 | Fibromatosis, Aggressive | Tamoxifen | 3.99 | 19069698 | |
| MESH:D005354 | Fibrosarcoma | Methylcholanthrene | 4.75 | 14633661 10962813 | |
| MESH:D005355 | Fibrosis | Cyclosporine | 13.78 | 12639820 12168785 | |
| MESH:D005355 | Fibrosis | Hydrochloric Acid | 13.78 | 18497604 | |
| MESH:D005355 | Fibrosis | Tetrachlorodibenzodioxin | 13.78 | 20067830 | |
| MESH:D005534 | Foot Diseases | Arsenic | 5.37 | 6392382 | |
| MESH:D005706 | Gallbladder Neoplasms | arsenic trioxide | 4.08 | 16904648 | |
| MESH:D005739 | Gas Poisoning | Hydrochloric Acid | 5.27 | 12378975 | |
| MESH:D005756 | Gastritis | Acetaminophen | 3.48 | 16983495 | |
| MESH:D005764 | Gastroesophageal Reflux | Hydrochloric Acid | 5.14 | 19957777 19951613 20616304 20516732 12212954 20545468 | |
| MESH:D005833 | Genital Neoplasms, Female | sodium arsenite | 4.49 | 16452187 | |
| MESH:D005885 | Gingival Hyperplasia | Cyclosporine | 4.03 | 8708960 | |
| MESH:D005909 | Glioblastoma | trichostatin A | 3.71 | 18801729 | |
| MESH:D006058 | Gonadal Disorders | Tetrachlorodibenzodioxin | 4.40 | 10696789 | |
| MESH:D006258 | Head and Neck Neoplasms | Cisplatin | 7.60 | 15464296 15102660 | |
| MESH:D006258 | Head and Neck Neoplasms | decitabine | 7.60 | 19215824 | |
| MESH:D034381 | Hearing Loss | Cisplatin | 4.13 | 19898482 | |
| MESH:D006319 | Hearing Loss, Sensorineural | Cisplatin | 4.26 | 15464296 | |
| MESH:D006356 | Heartburn | Hydrochloric Acid | 5.60 | 19566590 | |
| MESH:D006330 | Heart Defects, Congenital | Tetrachlorodibenzodioxin | 6.24 | 10048152 11294989 | |
| MESH:D006330 | Heart Defects, Congenital | Vitamin E | 6.24 | 16080930 | |
| MESH:D006333 | Heart Failure | Selenium | 2.96 | 17162251 | |
| MESH:D006457 | Hemoglobinuria, Paroxysmal | Cyclosporine | 4.23 | 15720958 | |
| MESH:D006470 | Hemorrhage | Tetrachlorodibenzodioxin | 3.16 | 11000095 | |
| MESH:D006529 | Hepatomegaly | Tetrachlorodibenzodioxin | 2.71 | 15340226 16120746 12621046 | |
| MESH:D006548 | Hernia, Diaphragmatic | Vitamin E | 2.64 | 16863852 16490937 | |
| MESH:D006558 | Herpes Genitalis | Estradiol | 4.84 | 15709030 | |
| MESH:D006689 | Hodgkin Disease | Cisplatin | 7.01 | 16170182 16200630 | |
| MESH:D006689 | Hodgkin Disease | sodium arsenite | 7.01 | 12676792 | |
| MESH:D019584 | Hot Flashes | Estradiol | 9.41 | 17088409 | |
| MESH:D019584 | Hot Flashes | Vitamin E | 9.41 | 14716179 | |
| MESH:D006869 | Hydronephrosis | Tetrachlorodibenzodioxin | 3.85 | 18606429 15340226 16354765 8697196 16959395 | |
| MESH:D006930 | Hyperalgesia | Acetaminophen | 2.55 | 16870215 | |
| MESH:D006940 | Hyperemia | Hydrochloric Acid | 5.46 | 12646421 | |
| MESH:D017488 | Hyperkeratosis, Epidermolytic | Arsenic | 4.29 | 17050553 | |
| MESH:D006973 | Hypertension | Arsenic | 8.16 | 16076760 11953799 9931084 | |
| MESH:D006973 | Hypertension | Cyclosporine | 8.16 | 10903974 | |
| MESH:D006973 | Hypertension | Tetrachlorodibenzodioxin | 8.16 | 18670907 18850075 | |
| MESH:D006975 | Hypertension, Portal | Hydrochloric Acid | 5.16 | 16984587 | |
| MESH:D006976 | Hypertension, Pulmonary | Hydrochloric Acid | 4.32 | 19262391 | |
| MESH:D006987 | Hypesthesia | Arsenic | 5.37 | 16093927 | |
| MESH:D007021 | Hypospadias | Ethinyl Estradiol | 3.62 | 16945680 16569931 | |
| MESH:D007022 | Hypotension | Hydrochloric Acid | 4.58 | 11574821 | |
| MESH:D007247 | Infertility, Female | Ethinyl Estradiol | 3.28 | 12013081 | |
| MESH:D007248 | Infertility, Male | decitabine | 10.50 | 17581917 | |
| MESH:D007248 | Infertility, Male | Ethinyl Estradiol | 10.50 | 17937319 | |
| MESH:D007248 | Infertility, Male | sodium arsenite | 10.50 | 12646999 15346721 | |
| MESH:D007249 | Inflammation | Diethylnitrosamine | 11.19 | 18785209 | |
| MESH:D007249 | Inflammation | Hydrochloric Acid | 11.19 | 11574821 | |
| MESH:D007249 | Inflammation | Tamoxifen | 11.19 | 19457130 | |
| MESH:D007249 | Inflammation | Tetrachlorodibenzodioxin | 11.19 | 12200463 12878042 | |
| MESH:D007251 | Influenza, Human | Selenium | 10.31 | 16624496 | |
| MESH:D007251 | Influenza, Human | Vitamin E | 10.31 | 16624496 | |
| MESH:D007333 | Insulin Resistance | Estradiol | 2.84 | 16393666 16627594 | |
| MESH:D007410 | Intestinal Diseases | Hydrochloric Acid | 4.78 | 11574821 | |
| MESH:D007569 | Jaw Abnormalities | Tetrachlorodibenzodioxin | 3.16 | 16580747 | |
| MESH:D007638 | Keratoconjunctivitis Sicca | Cyclosporine | 4.25 | 15604871 | |
| MESH:D007642 | Keratosis | Arsenic | 4.80 | 16930632 12749816 | |
| MESH:D007673 | Kidney Cortex Necrosis | Cisplatin | 4.95 | 15464296 | |
| MESH:D007674 | Kidney Diseases | Acetaminophen | 22.45 | 15629191 12587719 | |
| MESH:D007674 | Kidney Diseases | Cisplatin | 22.45 | 15190930 19839026 12649298 18289764 12231392 | |
| MESH:D007674 | Kidney Diseases | Cyclosporine | 22.45 | 18776723 10903974 8314463 | |
| MESH:D007674 | Kidney Diseases | Estradiol | 22.45 | 15618244 | |
| MESH:D007674 | Kidney Diseases | sodium arsenite | 22.45 | 20008137 | |
| MESH:D007674 | Kidney Diseases | Vitamin E | 22.45 | 12488133 | |
| MESH:D007676 | Kidney Failure, Chronic | Selenium | 3.71 | 16518626 | |
| MESH:D007680 | Kidney Neoplasms | 2,4-dinitrotoluene | 16.47 | 16705839 | |
| MESH:D007680 | Kidney Neoplasms | Cyclosporine | 16.47 | 12371664 | |
| MESH:D007680 | Kidney Neoplasms | Estradiol | 16.47 | 15610895 | |
| MESH:D007680 | Kidney Neoplasms | Tamoxifen | 16.47 | 18625569 | |
| MESH:D007683 | Kidney Tubular Necrosis, Acute | Cisplatin | 4.60 | 11231351 | |
| MESH:D007818 | Laryngeal Diseases | Hydrochloric Acid | 6.17 | 16498863 | |
| MESH:D007826 | Laryngismus | Hydrochloric Acid | 6.17 | 11510729 | |
| MESH:D007938 | Leukemia | arsenic trioxide | 6.14 | 15070760 | |
| MESH:D007938 | Leukemia | decitabine | 6.14 | 18980019 19235587 | |
| MESH:D015459 | Leukemia-Lymphoma, Adult T-Cell | arsenic trioxide | 3.62 | 12560223 17077332 | |
| MESH:D007948 | Leukemia, Monocytic, Acute | arsenic trioxide | 4.11 | 16972261 | |
| MESH:D015464 | Leukemia, Myelogenous, Chronic, BCR-ABL Positive | arsenic trioxide | 3.29 | 14633726 | |
| MESH:D007951 | Leukemia, Myeloid | arsenic trioxide | 9.01 | 19077051 | |
| MESH:D007951 | Leukemia, Myeloid | decitabine | 9.01 | 18454857 17236224 19117987 | |
| MESH:D015470 | Leukemia, Myeloid, Acute | arsenic trioxide | 6.05 | 16467208 16968895 19850784 20471514 17050201 | |
| MESH:D015470 | Leukemia, Myeloid, Acute | decitabine | 6.05 | 18206229 18704418 19387464 19010910 18460780 17679729 | |
| MESH:D015470 | Leukemia, Myeloid, Acute | trichostatin A | 6.05 | 18206229 | |
| MESH:D015477 | Leukemia, Myelomonocytic, Chronic | decitabine | 5.27 | 18055864 | |
| MESH:D015473 | Leukemia, Promyelocytic, Acute | Arsenic | 7.37 | 17339181 | |
| MESH:D015473 | Leukemia, Promyelocytic, Acute | arsenic trioxide | 7.37 | 19035177 12018890 16823087 16966277 11468182 16330433 19642359 17217047 17107899 15336539 15622746 12712474 16112521 15748426 17649720 17712046 19075265 12679006 16891316 17869043 15213294 16331271 19225113 9834237 11161223 | |
| MESH:D015458 | Leukemia, T-Cell | arsenic trioxide | 4.17 | 16882451 | |
| MESH:D008064 | Lipidoses | Tamoxifen | 3.02 | 17567588 15342952 | |
| MESH:D008103 | Liver Cirrhosis | Diethylnitrosamine | 6.73 | 18665156 18522880 20032147 19638242 18407596 | |
| MESH:D008103 | Liver Cirrhosis | Hydrochloric Acid | 6.73 | 16984587 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | Estradiol | 4.75 | 14659978 14716833 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | Tamoxifen | 4.75 | 18564211 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | Tetrachlorodibenzodioxin | 4.75 | 12878042 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | Vitamin E | 4.75 | 16169303 | |
| MESH:D008107 | Liver Diseases | Acetaminophen | 6.24 | 19460945 16610002 12969438 16611625 11587558 12587719 19014921 19784758 | |
| MESH:D008107 | Liver Diseases | Arsenic | 6.24 | 11134558 | |
| MESH:D008107 | Liver Diseases | Diethylnitrosamine | 6.24 | 17034775 | |
| MESH:D017114 | Liver Failure, Acute | Acetaminophen | 3.07 | 17185352 16871587 | |
| MESH:D008113 | Liver Neoplasms | Arsenic | 20.79 | 16368122 | |
| MESH:D008113 | Liver Neoplasms | arsenic trioxide | 20.79 | 14682389 | |
| MESH:D008113 | Liver Neoplasms | Diethylnitrosamine | 20.79 | 19833225 19551842 12771043 20434301 20137499 19090486 18754104 20583210 18644402 15175105 21047994 19996281 20492335 20101389 19256749 20501860 9163691 16942905 19690152 20118626 19812893 21167192 10737359 15885732 20452335 19254457 20405173 2862719 21278145 19427195 19426721 19850985 12112319 18977376 19638242 19255062 19499222 21071580 19294768 19642983 2422723 19073162 18978307 18648771 | |
| MESH:D008113 | Liver Neoplasms | Mitomycin | 20.79 | 15113037 | |
| MESH:D008113 | Liver Neoplasms | sodium arsenite | 20.79 | 16712894 15276417 | |
| MESH:D008113 | Liver Neoplasms | Tamoxifen | 20.79 | 16684651 | |
| MESH:D008113 | Liver Neoplasms | Tetrachlorodibenzodioxin | 20.79 | 16984957 | |
| MESH:D008114 | Liver Neoplasms, Experimental | arsenic trioxide | 13.17 | 20377131 | |
| MESH:D008114 | Liver Neoplasms, Experimental | Diethylnitrosamine | 13.17 | 19004024 18775883 18253720 18093689 18164116 19009564 18282651 17942915 2563599 3124819 17174075 19539802 18308698 18544905 21159647 16267830 17854601 18079962 16842330 19126423 9362446 19519916 | |
| MESH:D008114 | Liver Neoplasms, Experimental | Methylcholanthrene | 13.17 | 1399818 598648 | |
| MESH:D008114 | Liver Neoplasms, Experimental | Tetrachlorodibenzodioxin | 13.17 | 12151625 | |
| MESH:D008133 | Long QT Syndrome | arsenic trioxide | 3.21 | 15213294 | |
| MESH:D008171 | Lung Diseases | Hydrochloric Acid | 11.76 | 16784557 | |
| MESH:D008171 | Lung Diseases | sodium arsenite | 11.76 | 19095001 | |
| MESH:D008171 | Lung Diseases | Vitamin E | 11.76 | 16863852 | |
| MESH:D055370 | Lung Injury | Asbestos, Crocidolite | 8.95 | 17365036 | |
| MESH:D055370 | Lung Injury | Hydrochloric Acid | 8.95 | 18497604 18573544 19262391 15044056 21311175 18339021 20597076 16129981 15607125 19644408 15090967 21114838 17627322 11395602 | |
| MESH:D008175 | Lung Neoplasms | marker/mechanism | 18337602 | ||
| MESH:D008175 | Lung Neoplasms | Arsenic | 22.76 | 17976673 17306315 19168569 | |
| MESH:D008175 | Lung Neoplasms | arsenic trioxide | 22.76 | 19825857 11798837 | |
| MESH:D008175 | Lung Neoplasms | Asbestos | 22.76 | 12111688 | |
| MESH:D008175 | Lung Neoplasms | bexarotene | 22.76 | 17849452 | |
| MESH:D008175 | Lung Neoplasms | Cisplatin | 22.76 | 11798837 6189445 17225452 | |
| MESH:D008175 | Lung Neoplasms | Diethylnitrosamine | 22.76 | 20512841 20970405 21163286 6695378 | |
| MESH:D008175 | Lung Neoplasms | Methylcholanthrene | 22.76 | 20970405 1399818 10545420 16271038 11893704 9230183 21163286 17909032 6695378 20512841 16337739 15390079 7750092 | |
| MESH:D008175 | Lung Neoplasms | sodium arsenite | 22.76 | 17077188 16712894 19931552 15276417 17306315 | |
| MESH:D008175 | Lung Neoplasms | Tamoxifen | 22.76 | 18625569 | |
| MESH:D008175 | Lung Neoplasms | Tetrachlorodibenzodioxin | 22.76 | 19555203 11884234 | |
| MESH:D008175 | Lung Neoplasms | vinyl carbamate | 22.76 | 16247444 12117777 15172992 16885199 12438228 17361011 12765245 11134547 14755239 17363558 11195469 15824018 17163412 | |
| MESH:D008175 | Lung Neoplasms | Vitamin E | 22.76 | 11062179 | |
| MESH:D008223 | Lymphoma | decitabine | 3.28 | 19470736 | |
| MESH:D016410 | Lymphoma, T-Cell, Cutaneous | bexarotene | 4.96 | 11161223 | |
| MESH:D015674 | Mammary Neoplasms, Animal | Tamoxifen | 3.57 | 19428831 | |
| MESH:D008325 | Mammary Neoplasms, Experimental | 2,4-diaminotoluene | 17.55 | 11921183 | |
| MESH:D008325 | Mammary Neoplasms, Experimental | bexarotene | 17.55 | 19196723 19196722 15591091 | |
| MESH:D008325 | Mammary Neoplasms, Experimental | Estradiol | 17.55 | 17203775 11807958 11408345 16891317 | |
| MESH:D008325 | Mammary Neoplasms, Experimental | Selenium | 17.55 | 15318939 | |
| MESH:D008325 | Mammary Neoplasms, Experimental | Tamoxifen | 17.55 | 11731420 16827153 14580682 19196722 19196723 | |
| MESH:D020149 | Manganese Poisoning | Estradiol | 12.00 | 19453300 | |
| MESH:D020149 | Manganese Poisoning | Tamoxifen | 12.00 | 19453300 | |
| MESH:D008545 | Melanoma | Cisplatin | 9.44 | 16248763 12883367 15577323 12374674 18505091 18332650 16432458 11135225 16809738 17023156 18176117 12393984 17761969 | |
| MESH:D008545 | Melanoma | decitabine | 9.44 | 17785578 16505122 | |
| MESH:D008545 | Melanoma | sodium arsenite | 9.44 | 19082730 16487513 | |
| MESH:D008545 | Melanoma | Tamoxifen | 9.44 | 19393235 12393984 | |
| MESH:D008545 | Melanoma | trichostatin A | 9.44 | 16505122 | |
| MESH:D018328 | Melanoma, Amelanotic | Cisplatin | 10.87 | 15990972 | |
| MESH:D018328 | Melanoma, Amelanotic | Tamoxifen | 10.87 | 15990972 | |
| MESH:D008546 | Melanoma, Experimental | Acetaminophen | 3.38 | 19513568 | |
| MESH:D008654 | Mesothelioma | marker/mechanism | 15639718 12082623 | ||
| MESH:D008654 | Mesothelioma | Asbestos | 13.99 | 18709470 16564556 18310086 16919927 16319530 | |
| MESH:D008654 | Mesothelioma | Asbestos, Crocidolite | 13.99 | 16166281 18303189 16966607 | |
| MESH:D008654 | Mesothelioma | Cisplatin | 13.99 | 17638057 | |
| MESH:D008654 | Mesothelioma | Selenium | 13.99 | 15107826 | |
| MESH:D008664 | Metal Metabolism, Inborn Errors | Cyclosporine | 4.59 | 16801185 | |
| MESH:D009101 | Multiple Myeloma | arsenic trioxide | 11.45 | 11468182 19417148 15949261 14977855 19549372 | |
| MESH:D009101 | Multiple Myeloma | decitabine | 11.45 | 18172295 | |
| MESH:D009101 | Multiple Myeloma | trichostatin A | 11.45 | 18172295 | |
| MESH:D009182 | Mycosis Fungoides | arsenic trioxide | 4.48 | 18349030 | |
| MESH:D009190 | Myelodysplastic Syndromes | arsenic trioxide | 7.14 | 16105982 16882451 | |
| MESH:D009190 | Myelodysplastic Syndromes | decitabine | 7.14 | 19157545 16882708 19010910 18608210 | |
| MESH:D009203 | Myocardial Infarction | Hydrochloric Acid | 3.73 | 18534312 | |
| MESH:D017202 | Myocardial Ischemia | Arsenic | 8.50 | 15371236 | |
| MESH:D017202 | Myocardial Ischemia | Tetrachlorodibenzodioxin | 8.50 | 12213967 | |
| MESH:D015428 | Myocardial Reperfusion Injury | Estradiol | 3.13 | 16810080 | |
| MESH:D009336 | Necrosis | 2,4-dinitrotoluene | 3.67 | 18551238 | |
| MESH:D009361 | Neoplasm Invasiveness | arsenic trioxide | 3.78 | 16624393 | |
| MESH:D009362 | Neoplasm Metastasis | Diethylnitrosamine | 5.48 | 3581430 9029167 | |
| MESH:D009362 | Neoplasm Metastasis | Tamoxifen | 5.48 | 19393235 | |
| MESH:D009364 | Neoplasm Recurrence, Local | Tamoxifen | 2.45 | 19410462 | |
| MESH:D009369 | Neoplasms | Cisplatin | 7.86 | 16773208 | |
| MESH:D009369 | Neoplasms | decitabine | 7.86 | 19116145 17925555 19470736 | |
| MESH:D009369 | Neoplasms | sodium arsenite | 7.86 | 11559025 | |
| MESH:D009374 | Neoplasms, Experimental | sodium arsenite | 3.48 | 20056578 | |
| MESH:D009376 | Neoplasms, Hormone-Dependent | bexarotene | 10.29 | 19196722 | |
| MESH:D009376 | Neoplasms, Hormone-Dependent | Tamoxifen | 10.29 | 19189210 19196722 19200415 | |
| MESH:D009389 | Neovascularization, Pathologic | Estradiol | 3.54 | 17289903 | |
| MESH:D009395 | Nephritis, Interstitial | Cisplatin | 4.30 | 15464296 | |
| MESH:D009402 | Nephrosis, Lipoid | Cyclosporine | 4.25 | 17954296 | |
| MESH:D009404 | Nephrotic Syndrome | Cyclosporine | 3.12 | 18481113 19348381 | |
| MESH:D009421 | Nervous System Malformations | Estradiol | 8.85 | 16427766 11399458 | |
| MESH:D009421 | Nervous System Malformations | Tetrachlorodibenzodioxin | 8.85 | 14600291 | |
| MESH:D009436 | Neural Tube Defects | Arsenic | 11.49 | 16620997 | |
| MESH:D009436 | Neural Tube Defects | arsenic trioxide | 11.49 | 10525206 | |
| MESH:D009436 | Neural Tube Defects | sodium arsenite | 11.49 | 12854658 | |
| MESH:D009447 | Neuroblastoma | Cisplatin | 3.35 | 8761367 | |
| MESH:D019636 | Neurodegenerative Diseases | Acetaminophen | 7.66 | 18514411 | |
| MESH:D019636 | Neurodegenerative Diseases | Diethylnitrosamine | 7.66 | 20387270 | |
| MESH:D017599 | Neuroectodermal Tumors | Cisplatin | 4.51 | 8761367 | |
| MESH:D020078 | Neurogenic Inflammation | Arsenic | 4.20 | 17056641 | |
| MESH:D009461 | Neurologic Manifestations | Diethylnitrosamine | 4.92 | 20387270 | |
| MESH:D009784 | Occupational Diseases | 2,4-dinitrotoluene | 8.82 | 16049721 12819281 | |
| MESH:D009784 | Occupational Diseases | Hydrochloric Acid | 8.82 | 12378975 | |
| MESH:D010051 | Ovarian Neoplasms | Arsenic | 22.02 | 17306315 | |
| MESH:D010051 | Ovarian Neoplasms | arsenic trioxide | 22.02 | 12452020 19769630 16624393 | |
| MESH:D010051 | Ovarian Neoplasms | Cisplatin | 22.02 | 15464296 19769630 17225452 6897625 | |
| MESH:D010051 | Ovarian Neoplasms | decitabine | 22.02 | 19259094 19331143 | |
| MESH:D010051 | Ovarian Neoplasms | Estradiol | 22.02 | 19401270 | |
| MESH:D010051 | Ovarian Neoplasms | sodium arsenite | 22.02 | 15276417 17306315 | |
| MESH:D010051 | Ovarian Neoplasms | trichostatin A | 22.02 | 19331143 | |
| MESH:D010146 | Pain | Acetaminophen | 2.24 | 16870215 | |
| MESH:D010190 | Pancreatic Neoplasms | arsenic trioxide | 19.63 | 15580305 | |
| MESH:D010190 | Pancreatic Neoplasms | Cisplatin | 19.63 | 19003803 | |
| MESH:D010190 | Pancreatic Neoplasms | decitabine | 19.63 | 19294695 | |
| MESH:D010190 | Pancreatic Neoplasms | Diethylnitrosamine | 19.63 | 16540662 | |
| MESH:D010190 | Pancreatic Neoplasms | Mitomycin | 19.63 | 15113037 | |
| MESH:D010190 | Pancreatic Neoplasms | trichostatin A | 19.63 | 19294695 | |
| MESH:D016584 | Panic Disorder | Ethinyl Estradiol | 3.51 | 11578682 | |
| MESH:D010235 | Paraganglioma | arsenic trioxide | 3.98 | 19927285 | |
| MESH:D010382 | Peliosis Hepatis | Tetrachlorodibenzodioxin | 4.06 | 12520081 | |
| MESH:D010523 | Peripheral Nervous System Diseases | Arsenic | 9.45 | 16093927 | |
| MESH:D010523 | Peripheral Nervous System Diseases | Cisplatin | 9.45 | 15464296 | |
| MESH:D016491 | Peripheral Vascular Diseases | Arsenic | 4.80 | 6392382 16905509 15371236 | |
| MESH:D010954 | Plasmacytoma | Selenium | 4.70 | 15087411 | |
| MESH:D010995 | Pleural Diseases | Asbestos, Crocidolite | 4.70 | 10923243 | |
| MESH:D010997 | Pleural Neoplasms | Cisplatin | 5.15 | 17638057 | |
| MESH:D011015 | Pneumonia, Aspiration | Hydrochloric Acid | 5.18 | 18573544 15970105 18497604 15607125 | |
| MESH:D017119 | Porphyria Cutanea Tarda | Tetrachlorodibenzodioxin | 3.37 | 18163543 | |
| MESH:D011230 | Precancerous Conditions | Cyclosporine | 8.41 | 12371664 | |
| MESH:D011230 | Precancerous Conditions | Diethylnitrosamine | 8.41 | 2563599 | |
| MESH:D011297 | Prenatal Exposure Delayed Effects | Tetrachlorodibenzodioxin | 3.00 | 11222880 11896295 11399792 11118676 | |
| MESH:D055728 | Primary Myelofibrosis | decitabine | 11.80 | 17616702 | |
| MESH:D055728 | Primary Myelofibrosis | trichostatin A | 11.80 | 17616702 | |
| MESH:D019048 | Prostatic Intraepithelial Neoplasia | Estradiol | 3.71 | 20887781 | |
| MESH:D011471 | Prostatic Neoplasms | Arsenic | 2.07 | 16140617 | |
| MESH:D011471 | Prostatic Neoplasms | arsenic trioxide | 2.07 | 19131511 | |
| MESH:D011471 | Prostatic Neoplasms | Estradiol | 2.07 | 16740699 | |
| MESH:D011471 | Prostatic Neoplasms | sodium arsenite | 2.07 | 16039940 | |
| MESH:D011471 | Prostatic Neoplasms | Tamoxifen | 2.07 | 15067354 | |
| MESH:D011471 | Prostatic Neoplasms | trichostatin A | 2.07 | 18798265 19789329 | |
| MESH:D011471 | Prostatic Neoplasms | Vitamin E | 2.07 | 15084515 | |
| MESH:D011507 | Proteinuria | Arsenic | 3.83 | 21343184 | |
| MESH:D011537 | Pruritus | Ethinyl Estradiol | 3.12 | 16919318 15861022 | |
| MESH:D011565 | Psoriasis | Cyclosporine | 2.16 | 16882103 | |
| MESH:D001261 | Pulmonary Atelectasis | Hydrochloric Acid | 5.82 | 20597076 | |
| MESH:D011654 | Pulmonary Edema | Hydrochloric Acid | 5.02 | 15090967 | |
| MESH:D011658 | Pulmonary Fibrosis | Asbestos, Crocidolite | 2.96 | 17975199 15814490 17365031 17322281 | |
| MESH:D051437 | Renal Insufficiency | Cisplatin | 4.22 | 15464296 | |
| MESH:D012128 | Respiratory Distress Syndrome, Adult | Hydrochloric Acid | 4.58 | 16129981 16784557 18339021 18549715 17627322 | |
| MESH:D012133 | Respiratory Paralysis | Hydrochloric Acid | 6.17 | 11510729 | |
| MESH:D015619 | Respiratory System Abnormalities | Tetrachlorodibenzodioxin | 3.65 | 18990726 | |
| MESH:D012140 | Respiratory Tract Diseases | Hydrochloric Acid | 4.97 | 20516732 | |
| MESH:D012208 | Rhabdomyosarcoma | decitabine | 4.22 | 19155313 | |
| MESH:D012512 | Sarcoma, Ewing's | arsenic trioxide | 9.73 | 16646077 | |
| MESH:D012512 | Sarcoma, Ewing's | Cisplatin | 9.73 | 14601052 | |
| MESH:D012640 | Seizures | 2,4-dinitrotoluene | 2.41 | 18551238 | |
| MESH:D012871 | Skin Diseases | Arsenic | 4.87 | 17938729 16759981 17453740 16353154 18709164 19834688 16702368 15952646 17050553 17548696 6392382 | |
| MESH:D012871 | Skin Diseases | Vitamin E | 4.87 | 18709164 | |
| MESH:D012878 | Skin Neoplasms | Arsenic | 8.96 | 17976673 16251483 15504454 17050553 19538983 17029826 | |
| MESH:D012878 | Skin Neoplasms | sodium arsenite | 8.96 | 18572023 19524636 | |
| MESH:D012878 | Skin Neoplasms | Tetrachlorodibenzodioxin | 8.96 | 16192470 | |
| MESH:D055752 | Small Cell Lung Carcinoma | Cisplatin | 5.15 | 15464296 | |
| MESH:D013088 | Spermatocele | Ethinyl Estradiol | 10.92 | 16709447 | |
| MESH:D013088 | Spermatocele | Tamoxifen | 10.92 | 16709447 | |
| MESH:D013119 | Spinal Cord Injuries | Tamoxifen | 3.85 | 19457130 | |
| MESH:D016135 | Spinal Dysraphism | sodium arsenite | 3.65 | 12854658 | |
| MESH:D013274 | Stomach Neoplasms | arsenic trioxide | 4.60 | 17007042 | |
| MESH:D013274 | Stomach Neoplasms | Cisplatin | 4.60 | 17522103 18396642 15958060 | |
| MESH:D013274 | Stomach Neoplasms | decitabine | 4.60 | 19037991 | |
| MESH:D013274 | Stomach Neoplasms | Diethylnitrosamine | 4.60 | 18456281 | |
| MESH:D013276 | Stomach Ulcer | Hydrochloric Acid | 4.06 | 16755016 17189318 15309881 | |
| MESH:D020521 | Stroke | Vitamin E | 3.37 | 16517955 | |
| MESH:D013736 | Testicular Neoplasms | Cisplatin | 4.45 | 15464296 17225452 | |
| MESH:D019851 | Thrombophilia | Ethinyl Estradiol | 3.44 | 11994571 | |
| MESH:D013927 | Thrombosis | Ethinyl Estradiol | 2.99 | 15669648 | |
| MESH:D013959 | Thyroid Diseases | Tetrachlorodibenzodioxin | 3.71 | 12697716 | |
| MESH:D013964 | Thyroid Neoplasms | arsenic trioxide | 15.98 | 19014326 | |
| MESH:D013964 | Thyroid Neoplasms | Butyrates | 15.98 | 17967635 | |
| MESH:D013964 | Thyroid Neoplasms | decitabine | 15.98 | 17967635 | |
| MESH:D013964 | Thyroid Neoplasms | Diethylnitrosamine | 15.98 | 7505956 | |
| MESH:D013978 | Tibial Fractures | Estradiol | 4.49 | 19048282 | |
| MESH:D016171 | Torsades de Pointes | arsenic trioxide | 3.77 | 15213294 | |
| MESH:D001749 | Urinary Bladder Neoplasms | marker/mechanism | 15987713 | ||
| MESH:D001749 | Urinary Bladder Neoplasms | 2,4-dinitrotoluene | 23.00 | 16049721 | |
| MESH:D001749 | Urinary Bladder Neoplasms | Arsenic | 23.00 | 18640142 11144890 19322015 17306315 19429237 15987713 17976673 | |
| MESH:D001749 | Urinary Bladder Neoplasms | arsenic trioxide | 23.00 | 20435036 11780464 12845720 12973940 | |
| MESH:D001749 | Urinary Bladder Neoplasms | Cisplatin | 23.00 | 15464296 12973940 17225452 | |
| MESH:D001749 | Urinary Bladder Neoplasms | decitabine | 23.00 | 19087683 17616700 | |
| MESH:D001749 | Urinary Bladder Neoplasms | sodium arsenite | 23.00 | 17306315 16712894 16452187 11723127 | |
| MESH:D001749 | Urinary Bladder Neoplasms | Tamoxifen | 23.00 | 16712894 8653321 17572228 | |
| MESH:D014571 | Urologic Neoplasms | 2,4-dinitrotoluene | 4.12 | 10091137 | |
| MESH:D014581 | Urticaria | Acetaminophen | 2.80 | 10982225 | |
| MESH:D002583 | Uterine Cervical Neoplasms | Cisplatin | 9.05 | 16803524 | |
| MESH:D002583 | Uterine Cervical Neoplasms | sodium arsenite | 9.05 | 11813266 | |
| MESH:D014594 | Uterine Neoplasms | Ethinyl Estradiol | 3.12 | 14692618 | |
| MESH:D014604 | Uveal Neoplasms | decitabine | 4.72 | 17785578 | |
| MESH:D014605 | Uveitis | Cyclosporine | 3.79 | 1336536 | |
| MESH:D014625 | Vaginal Neoplasms | Cisplatin | 4.42 | 15577323 | |
| MESH:D014652 | Vascular Diseases | Arsenic | 11.21 | 17056641 | |
| MESH:D014652 | Vascular Diseases | sodium arsenite | 11.21 | 17056641 | |
| MESH:D054079 | Vascular Malformations | Tetrachlorodibenzodioxin | 4.40 | 12125929 | |
| MESH:D020246 | Venous Thrombosis | Ethinyl Estradiol | 3.37 | 14671159 15869587 | |
| MESH:D014839 | Vomiting | Cisplatin | 4.53 | 11897121 | |
| MESH:D019282 | Wasting Syndrome | Tetrachlorodibenzodioxin | 4.06 | 15886252 | |
| MESH:D014985 | Xerophthalmia | Cyclosporine | 4.25 | 17120751 |
| Pathway ID | Pathway Name |
|---|---|
| KEGG:05219 | Bladder cancer |
| KEGG:05223 | Non-small cell lung cancer |
| KEGG:05200 | Pathways in cancer |
Drug Bank