Annotation Detail for SUPT16H
Basic Information
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| Gene Symbol: | SUPT16H ( CDC68,FACTP140,FLJ10857,FLJ14010,FLJ34357,SPT16/CDC68 ) |
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| Gene Full Name: | suppressor of Ty 16 homolog (S. cerevisiae) |
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| Band: | 14q11.2 |
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| Quick Links | Entrez ID:11198; OMIM: 605012; Uniprot ID:SP16H_HUMAN; ENSEMBL ID: ENSG00000092201; HGNC ID: 11465 |
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| Relate to Another Database: |
SFARIGene;
denovo-db |
| Pathway ID | Pathway Name |
|---|
| Elongation arrest and recovery |
| Pausing and recovery of elongation |
| Transcription |
| Gene Expression |
| HIV Infection |
| Pathway ID | Pathway Name |
|---|
| 500949 | RNA Polymerase II Pre-transcription Events |
| Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
|---|
| C023514 |
2,6-dinitrotoluene |
2,6-dinitrotoluene affects the expression of SUPT16H mRNA | affects expression | 21346803
|
| D001564 |
Benzo(a)pyrene |
Benzo(a)pyrene results in increased expression of SUPT16H mRNA | increases expression | 17879257
|
| Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
|---|
| MESH:D000230 |
Adenocarcinoma |
|
Benzo(a)pyrene |
2.07 | 20464547 20127859 |
| MESH:D000236 |
Adenoma |
|
Benzo(a)pyrene |
2.90 | 6695378 |
| MESH:D017544 |
Aortic Aneurysm, Abdominal |
|
Benzo(a)pyrene |
4.84 | 19183758 |
| MESH:D001943 |
Breast Neoplasms |
|
Benzo(a)pyrene |
1.98 | 17474063 20146248 |
| MESH:D006528 |
Carcinoma, Hepatocellular |
|
2,6-dinitrotoluene |
1.79 | 16705839 |
| MESH:D002294 |
Carcinoma, Squamous Cell |
|
Benzo(a)pyrene |
2.15 | 20419170 |
| MESH:D002471 |
Cell Transformation, Neoplastic |
|
2,6-dinitrotoluene |
3.09 | 6135515 |
| MESH:D003490 |
Cyanosis |
|
2,6-dinitrotoluene |
4.78 | 18551238 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
2,6-dinitrotoluene |
2.07 | 21346803 18551238 |
| MESH:D004938 |
Esophageal Neoplasms |
|
Benzo(a)pyrene |
2.09 | 16530937 |
| MESH:D006330 |
Heart Defects, Congenital |
|
Benzo(a)pyrene |
2.87 | 20471113 |
| MESH:D007680 |
Kidney Neoplasms |
|
2,6-dinitrotoluene |
3.41 | 16705839 |
| MESH:D008113 |
Liver Neoplasms |
|
2,6-dinitrotoluene |
4.97 | 7678174 |
| MESH:D008113 |
Liver Neoplasms |
|
Benzo(a)pyrene |
4.97 | 21137059 20195826 |
| MESH:D008114 |
Liver Neoplasms, Experimental |
|
2,6-dinitrotoluene |
2.82 | 2876784 2876786 6135515 |
| MESH:D008175 |
Lung Neoplasms |
|
Benzo(a)pyrene |
1.57 | 20135361 17053015 20064080 18520028 20869020 18569708 18816296 6695378 20464547 |
| MESH:D009062 |
Mouth Neoplasms |
|
Benzo(a)pyrene |
3.57 | 16381670 |
| MESH:D009336 |
Necrosis |
|
2,6-dinitrotoluene |
4.75 | 18551238 7678174 |
| MESH:D009369 |
Neoplasms |
|
Benzo(a)pyrene |
2.36 | 11141357 |
| MESH:D009784 |
Occupational Diseases |
|
2,6-dinitrotoluene |
3.94 | 16049721 |
| MESH:D011471 |
Prostatic Neoplasms |
|
Benzo(a)pyrene |
2.90 | 17292933 |
| MESH:D012640 |
Seizures |
|
2,6-dinitrotoluene |
2.85 | 18551238 |
| MESH:D012878 |
Skin Neoplasms |
|
Benzo(a)pyrene |
2.55 | 10029692 19755658 |
| MESH:D013274 |
Stomach Neoplasms |
|
Benzo(a)pyrene |
1.56 | 20155912 2093021 |
| MESH:D001749 |
Urinary Bladder Neoplasms |
|
2,6-dinitrotoluene |
5.48 | 16049721 |
| MESH:D001749 |
Urinary Bladder Neoplasms |
|
Benzo(a)pyrene |
5.48 | 17053015 |
| MESH:D014571 |
Urologic Neoplasms |
|
2,6-dinitrotoluene |
5.20 | 10091137 |
Related Diseases/Disorders