AutismKB 2.0

Annotation Detail for RASSF8


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Basic Information Top
Gene Symbol:RASSF8 ( C12orf2,DKFZp434O0227,FLJ11542,HOJ1 )
Gene Full Name: Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
Band: 12p12.1
Quick LinksEntrez ID:11228; OMIM: 608231; Uniprot ID:RASF8_HUMAN; ENSEMBL ID: ENSG00000123094; HGNC ID: 13232
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000082 Acetaminophen Acetaminophen affects the expression of RASSF8 mRNAaffects expression 17562736
C006632 arsenic trioxide arsenic trioxide results in increased expression of RASSF8 mRNAincreases expression 15761015
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of RASSF8 mRNAdecreases expression 19150397
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000230 Adenocarcinoma arsenic trioxide 2.3619825857 11798837
MESH:D000799 Angioedema Acetaminophen 4.7110982225
MESH:D001321 Autistic Disorder Acetaminophen 1.3918445737
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 4.1516206674
MESH:D002051 Burkitt Lymphoma arsenic trioxide 4.8611589617
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 3.043084413
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 3.0411135700 15553829 14691202 16217749 15073043
MESH:D002291 Carcinoma, Papillary arsenic trioxide 5.7419014326
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 4.5712490120
MESH:D002386 Cataract Acetaminophen 2.8110977129
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 3.0120889678
MESH:D015179 Colorectal Neoplasms arsenic trioxide 1.8720501625
MESH:D023903 Coronary Restenosis arsenic trioxide 4.7712609071
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 1.8910525206
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 4.6315213294
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 1.6818071297 19370779 10915739 2444490 11529661 19923254 12958197 18713872 16227642 19164858 17522070 16485898 19416960 17562736 12705907 19420014 11461765 14986274 17906064 16393943 11287661 10774834 16781746 15968718 12540782 12594235 11834606 16177239 14550746 10663392 19739265 16109766 11421492 19085960 14725611 15619225 12392966 16081117 11739529 12153990 11743745
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.9619426721
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 4.7520426865
MESH:D004938 Esophageal Neoplasms arsenic trioxide 4.7512903497
MESH:D005234 Fatty Liver arsenic trioxide 3.7715073043
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 4.8516904648
MESH:D005756 Gastritis Acetaminophen 4.5416983495
MESH:D006930 Hyperalgesia Acetaminophen 3.0616870215
MESH:D007674 Kidney Diseases Acetaminophen 2.4215629191 12587719
MESH:D007938 Leukemia arsenic trioxide 3.0115070760
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 4.2812560223 17077332
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 5.0516972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 3.7514633726
MESH:D007951 Leukemia, Myeloid arsenic trioxide 4.2419077051
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 2.1920471514 16968895 16467208 17050201 19850784
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 3.4816823087 16330433 15213294 17217047 16891316 12712474 16966277 15748426 16112521 15336539 17649720 12679006 11468182 9834237 19225113 15622746 19035177 17712046 17107899 16331271 19642359 12018890 17869043 19075265 11161223
MESH:D015458 Leukemia, T-Cell arsenic trioxide 4.9416882451
MESH:D008107 Liver Diseases Acetaminophen 1.7116610002 12969438 11587558 19460945 12587719 19014921 16611625 19784758
MESH:D017114 Liver Failure, Acute Acetaminophen 3.6816871587 17185352
MESH:D008113 Liver Neoplasms arsenic trioxide 2.4714682389
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 2.9820377131
MESH:D008133 Long QT Syndrome arsenic trioxide 3.6915213294
MESH:D008175 Lung Neoplasms arsenic trioxide 1.8711798837 19825857
MESH:D008546 Melanoma, Experimental Acetaminophen 4.2219513568
MESH:D009101 Multiple Myeloma arsenic trioxide 3.4119417148 11468182 14977855 15949261 19549372
MESH:D009182 Mycosis Fungoides arsenic trioxide 5.5418349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 3.3616882451 16105982
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 4.5416624393
MESH:D009436 Neural Tube Defects arsenic trioxide 3.3810525206
MESH:D019636 Neurodegenerative Diseases Acetaminophen 3.2618514411
MESH:D010051 Ovarian Neoplasms arsenic trioxide 2.5119769630 12452020 16624393
MESH:D010146 Pain Acetaminophen 2.7716870215
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 2.6415580305
MESH:D010235 Paraganglioma arsenic trioxide 4.6919927285
MESH:D011471 Prostatic Neoplasms arsenic trioxide 3.2019131511
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 4.5416646077
MESH:D013274 Stomach Neoplasms arsenic trioxide 1.8617007042
MESH:D013964 Thyroid Neoplasms arsenic trioxide 3.4319014326
MESH:D016171 Torsades de Pointes arsenic trioxide 4.7015213294
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 2.6112973940 11780464 20435036 12845720
MESH:D014581 Urticaria Acetaminophen 3.5010982225
No data
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Syndromic Genes

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AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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