AutismKB 2.0

Annotation Detail for CMTM7


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Basic Information Top
Gene Symbol:CMTM7 ( CKLFSF7,FLJ30992 )
Gene Full Name: CKLF-like MARVEL transmembrane domain containing 7
Band: 3p22.3
Quick LinksEntrez ID:112616; OMIM: 607890; Uniprot ID:CKLF7_HUMAN; ENSEMBL ID: ENSG00000153551; HGNC ID: 19178
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C472791 3-(4'-hydroxy-3'-adamantylbiphenyl-4-yl)acrylic acid 3-(4'-hydroxy-3'-adamantylbiphenyl-4-yl)acrylic acid results in decreased expression of CMTM7 mRNAdecreases expression 16788091
D000082 Acetaminophen Acetaminophen affects the expression of CMTM7 mRNAaffects expression 17562736
D000638 Amiodarone Amiodarone results in increased expression of CMTM7 mRNAincreases expression 19774075
D001564 Benzo(a)pyrene Benzo(a)pyrene results in decreased expression of CMTM7 mRNAdecreases expression 20064835
C006253 pirinixic acid [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of CMTM7 mRNAaffects binding|decreases expression|increases activity 19710929
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D055371 Acute Lung Injury pirinixic acid 3.5218653653
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 2.0520127859 20464547
MESH:D000236 Adenoma Benzo(a)pyrene 2.846695378
MESH:D018248 Adenoma, Liver Cell pirinixic acid 4.0216434500
MESH:D000799 Angioedema Acetaminophen 4.4510982225
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 4.5619183758
MESH:D001145 Arrhythmias, Cardiac Amiodarone 4.1518218290 20041841 18057881
MESH:D001281 Atrial Fibrillation Amiodarone 4.1619698954 18651412
MESH:D001321 Autistic Disorder Acetaminophen 1.4018445737
MESH:D001778 Blood Coagulation Disorders Amiodarone 10.3519483382
MESH:D001778 Blood Coagulation Disorders pirinixic acid 10.3519483382
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 2.0017474063 20146248
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 1.403084413
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 2.1320419170
MESH:D002311 Cardiomyopathy, Dilated Amiodarone 2.9919225199 15710769
MESH:D002341 Carotid Artery Thrombosis Amiodarone 5.6218974383
MESH:D002386 Cataract Acetaminophen 2.7710977129
MESH:D002779 Cholestasis pirinixic acid 3.0819176532
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.5618249437
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 4.1511461765 16081117 12540782 19739265 10663392 11287661 14550746 10915739 11529661 16109766 17562736 17522070 16485898 11421492 10774834 17906064 12392966 15968718 16393943 11834606 19416960 2444490 18071297 16177239 16781746 14986274 11743745 19420014 18713872 15619225 11739529 12594235 12153990 19923254 19370779 19085960 14725611 16227642 12705907 12958197 19164858
MESH:D056486 Drug-Induced Liver Injury Amiodarone 4.1518218290 15265979
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.7119426721
MESH:D004487 Edema pirinixic acid 2.8512083418
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 2.0716530937
MESH:D005234 Fatty Liver Amiodarone 9.0714986274
MESH:D005234 Fatty Liver pirinixic acid 9.0719236843 20131406
MESH:D005756 Gastritis Acetaminophen 4.2916983495
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 2.8220471113
MESH:D006333 Heart Failure pirinixic acid 2.7320558911
MESH:D006529 Hepatomegaly Amiodarone 10.2415265979
MESH:D006529 Hepatomegaly pirinixic acid 10.2418467677 16221962 19772884 19176532
MESH:D006930 Hyperalgesia Acetaminophen 2.9916870215
MESH:D006937 Hypercholesterolemia Amiodarone 4.258137927 9751232
MESH:D006943 Hyperglycemia pirinixic acid 3.5320558911
MESH:D007037 Hypothyroidism Amiodarone 5.0018020914 17991464
MESH:D007333 Insulin Resistance pirinixic acid 2.8516306350
MESH:D007674 Kidney Diseases Acetaminophen 2.3815629191 12587719
MESH:D008064 Lipidoses Amiodarone 3.7615342952 17567588
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 1.3515474484
MESH:D008107 Liver Diseases Acetaminophen 1.6912587719 19784758 19014921 16611625 11587558 12969438 16610002 19460945
MESH:D017114 Liver Failure, Acute Acetaminophen 3.5817185352 16871587
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 4.7321137059 20195826
MESH:D008113 Liver Neoplasms pirinixic acid 4.7320007298 16377806 15890375
MESH:D008133 Long QT Syndrome Amiodarone 3.8515350150 17391786 11989578
MESH:D008171 Lung Diseases Amiodarone 3.6012587719
MESH:D017563 Lung Diseases, Interstitial Amiodarone 5.0918516814
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 1.5717053015 20869020 20464547 20064080 18520028 18816296 18569708 6695378 20135361
MESH:D008546 Melanoma, Experimental Acetaminophen 4.0519513568
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 3.4616381670
MESH:D009135 Muscular Diseases pirinixic acid 3.9916239165
MESH:D009181 Mycoses Amiodarone 5.5117974566 12754197
MESH:D009203 Myocardial Infarction pirinixic acid 2.2619151258
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 3.2216411023
MESH:D009369 Neoplasms Benzo(a)pyrene 5.3311141357
MESH:D009369 Neoplasms pirinixic acid 5.3317405874
MESH:D019636 Neurodegenerative Diseases Acetaminophen 3.1818514411
MESH:D009765 Obesity pirinixic acid 1.8820558911
MESH:D010146 Pain Acetaminophen 2.6916870215
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 2.9117292933
MESH:D011658 Pulmonary Fibrosis Amiodarone 2.9611597910 12832656 12490602
MESH:D015427 Reperfusion Injury pirinixic acid 2.5319058328
OMIM:609620 SHORT QT SYNDROME 1 Amiodarone 5.6218724381
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 2.5119755658 10029692
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 1.5620155912 2093021
MESH:D013276 Stomach Ulcer Amiodarone 3.6818087811
MESH:D013610 Tachycardia Amiodarone 4.7311238279
MESH:D017180 Tachycardia, Ventricular Amiodarone 4.6319225199
MESH:D013959 Thyroid Diseases Amiodarone 5.3719731979
MESH:D013971 Thyrotoxicosis Amiodarone 5.3418020914 19584973
MESH:D016171 Torsades de Pointes Amiodarone 4.7311989578 17467628
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 2.2917053015
MESH:D014581 Urticaria Acetaminophen 3.3810982225
No data
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Syndromic Genes

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AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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