Annotation Detail for SP140
Basic Information Top
| Gene Symbol: | SP140 ( LYSP100,LYSP100-A,LYSP100-B,MGC126440 ) |
|---|---|
| Gene Full Name: | SP140 nuclear body protein |
| Band: | 2q37.1 |
| Quick Links | Entrez ID:11262; OMIM: 608602; Uniprot ID:LY10_HUMAN; ENSEMBL ID: ENSG00000079263; HGNC ID: 17133 |
| Relate to Another Database: | SFARIGene; denovo-db |
Related Pathway Information| No data |
| Desease ID | Desease Name |
|---|---|
| 1809 | HIV infection |
| Desease Name |
|---|
| CANCER |
| Chronic lymphocytic leukemia |
| Desease Name |
|---|
| Chronic lymphocytic leukemia |
| No data |
| Chemical ID | Chemical Name | Interaction | Interaction Action | Publication |
|---|---|---|---|---|
| D017239 | Paclitaxel | SP140 protein affects the susceptibility to Paclitaxel | affects response to substance | 16217747 |
| Disease ID | Disease Name | Direct Evidence | Inference Chemical Name | Inference Score | Publication |
|---|---|---|---|---|---|
| MESH:D001859 | Bone Neoplasms | Paclitaxel | 5.26 | 15867366 | |
| MESH:D001943 | Breast Neoplasms | Paclitaxel | 2.86 | 16115903 15136595 18223236 18323546 11325840 16244791 18234424 16273361 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Paclitaxel | 2.57 | 16313753 | |
| MESH:D015179 | Colorectal Neoplasms | Paclitaxel | 2.45 | 18802399 | |
| MESH:D004938 | Esophageal Neoplasms | Paclitaxel | 2.99 | 16481741 | |
| MESH:D015451 | Leukemia, Lymphocytic, Chronic, B-Cell | marker/mechanism | 18758461 | ||
| MESH:D008080 | Liposarcoma | Paclitaxel | 5.52 | 17353645 | |
| MESH:D008228 | Lymphoma, Non-Hodgkin | Paclitaxel | 4.58 | 14749477 | |
| MESH:D008545 | Melanoma | Paclitaxel | 2.64 | 12040289 12025231 16342250 | |
| MESH:D009101 | Multiple Myeloma | Paclitaxel | 4.06 | 14749477 | |
| MESH:D009362 | Neoplasm Metastasis | Paclitaxel | 3.42 | 15867366 | |
| MESH:D010014 | Osteolysis | Paclitaxel | 6.07 | 15867366 | |
| MESH:D010051 | Ovarian Neoplasms | Paclitaxel | 3.11 | 11161223 | |
| MESH:D011471 | Prostatic Neoplasms | Paclitaxel | 3.78 | 16356831 17172428 16729912 17136230 | |
| MESH:D013274 | Stomach Neoplasms | Paclitaxel | 2.45 | 18396642 18506536 | |
| MESH:D024801 | Tauopathies | Paclitaxel | 5.90 | 16930453 |
| No data |