AutismKB 2.0

Annotation Detail for ATXN2L


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Basic Information Top
Gene Symbol:ATXN2L ( A2D,A2LG,A2LP,A2RP )
Gene Full Name: ataxin 2-like
Band: 16p11.2
Quick LinksEntrez ID:11273; OMIM: 607931; Uniprot ID:ATX2L_HUMAN; ENSEMBL ID: ENSG00000168488; HGNC ID: 31326
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D002330 Carmustine Carmustine results in decreased expression of ATXN2L mRNAdecreases expression 15980968
D019833 Genistein Genistein results in decreased expression of ATXN2L mRNAdecreases expression 16705744
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000230 Adenocarcinoma Genistein 2.5611473722
MESH:D001932 Brain Neoplasms Carmustine 4.8916187019
MESH:D001943 Breast Neoplasms Genistein 2.4816873071 16541309 17200150
MESH:D006528 Carcinoma, Hepatocellular Genistein 2.1816924424
MESH:D002318 Cardiovascular Diseases Genistein 3.6316332659
MESH:D003110 Colonic Neoplasms Genistein 2.3417182828
MESH:D003924 Diabetes Mellitus, Type 2 Genistein 2.5716647724
MESH:D004714 Endometrial Hyperplasia Genistein 5.4816402032
MESH:D016889 Endometrial Neoplasms Genistein 3.6611473722
MESH:D005909 Glioblastoma Carmustine 8.5516187019
MESH:D005909 Glioblastoma Genistein 8.5516598420
MESH:D007938 Leukemia Genistein 3.2218980019 17468513
MESH:D008106 Liver Cirrhosis, Experimental Genistein 2.0717823541
MESH:D008325 Mammary Neoplasms, Experimental Genistein 3.2312929590 14578162
MESH:D008545 Melanoma Carmustine 2.9112393984
MESH:D009203 Myocardial Infarction Genistein 3.0217141266
MESH:D015428 Myocardial Reperfusion Injury Genistein 4.0417141266
MESH:D009421 Nervous System Malformations Genistein 4.7116427766
MESH:D010024 Osteoporosis Genistein 3.5219401787
MESH:D015663 Osteoporosis, Postmenopausal Genistein 4.6916169203
MESH:D010051 Ovarian Neoplasms Genistein 2.7119005980
MESH:D011471 Prostatic Neoplasms Genistein 3.3915256057 15378649 16925846
No data
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA128394585
    • No data
    Releated disease ID Related disease Name
    PA446155Precursor Cell Lymphoblastic Leukemia-Lymphoma
    No data
    Drug Bank Top

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    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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