Annotation Detail for MGAT4B
Basic Information Top
| Gene Symbol: | MGAT4B ( GNT-IV,GNT-IVB ) |
|---|---|
| Gene Full Name: | mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B |
| Band: | 5q35.3 |
| Quick Links | Entrez ID:11282; OMIM: 604561; Uniprot ID:MGT4B_HUMAN; ENSEMBL ID: ENSG00000161013; HGNC ID: 7048 |
| Relate to Another Database: | SFARIGene; denovo-db |
| Chemical ID | Chemical Name | Interaction | Interaction Action | Publication |
|---|---|---|---|---|
| D000082 | Acetaminophen | Acetaminophen affects the expression of MGAT4B mRNA | affects expression | 17562736 |
| C079198 | S 1 (combination) | MGAT4B protein results in increased susceptibility to S 1 (combination) | increases response to substance | 16734730 |
| Disease ID | Disease Name | Direct Evidence | Inference Chemical Name | Inference Score | Publication |
|---|---|---|---|---|---|
| MESH:D000799 | Angioedema | Acetaminophen | 4.91 | 10982225 | |
| MESH:D001321 | Autistic Disorder | Acetaminophen | 1.39 | 18445737 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Acetaminophen | 1.41 | 3084413 | |
| MESH:D002289 | Carcinoma, Non-Small-Cell Lung | S 1 (combination) | 4.19 | 18212800 18347146 | |
| MESH:D002294 | Carcinoma, Squamous Cell | S 1 (combination) | 3.95 | 15984520 | |
| MESH:D002386 | Cataract | Acetaminophen | 2.83 | 10977129 | |
| MESH:D056486 | Drug-Induced Liver Injury | Acetaminophen | 1.68 | 17522070 18071297 19416960 19164858 11421492 12392966 16109766 19370779 19923254 12594235 14986274 19420014 16227642 15619225 11461765 10663392 16081117 17562736 2444490 12153990 11287661 11529661 19739265 16393943 12958197 11743745 10915739 12705907 16177239 12540782 19085960 14550746 15968718 11739529 11834606 10774834 16781746 18713872 14725611 16485898 17906064 | |
| MESH:D056487 | Drug-Induced Liver Injury, Chronic | Acetaminophen | 5.17 | 19426721 | |
| MESH:D005706 | Gallbladder Neoplasms | S 1 (combination) | 6.44 | 19093184 | |
| MESH:D005756 | Gastritis | Acetaminophen | 4.74 | 16983495 | |
| MESH:D006258 | Head and Neck Neoplasms | S 1 (combination) | 5.06 | 15984520 18607998 | |
| MESH:D006930 | Hyperalgesia | Acetaminophen | 3.11 | 16870215 | |
| MESH:D007674 | Kidney Diseases | Acetaminophen | 2.44 | 12587719 15629191 | |
| MESH:D008107 | Liver Diseases | Acetaminophen | 1.71 | 19014921 12587719 12969438 16610002 19460945 11587558 19784758 16611625 | |
| MESH:D017114 | Liver Failure, Acute | Acetaminophen | 3.74 | 17185352 16871587 | |
| MESH:D008546 | Melanoma, Experimental | Acetaminophen | 4.33 | 19513568 | |
| MESH:D019636 | Neurodegenerative Diseases | Acetaminophen | 3.31 | 18514411 | |
| MESH:D010146 | Pain | Acetaminophen | 2.82 | 16870215 | |
| MESH:D013274 | Stomach Neoplasms | S 1 (combination) | 3.37 | 18506536 18553229 16557585 | |
| MESH:D014581 | Urticaria | Acetaminophen | 3.58 | 10982225 |
| Pathway ID | Pathway Name |
|---|---|
| KEGG:01100 | Metabolic pathways |
| REACT:17015 | Metabolism of proteins |
| KEGG:00510 | N-Glycan biosynthesis |
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