Annotation Detail for CASC4
Basic Information
Top
| Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
|---|
| D006830 |
Hydralazine |
[Hydralazine co-treated with Valproic Acid] results in increased expression of CASC4 mRNA | affects cotreatment|increases expression | 17183730
|
| D015741 |
Metribolone |
Metribolone results in increased expression of CASC4 mRNA | increases expression | 17010196
|
| C006253 |
pirinixic acid |
pirinixic acid results in increased expression of CASC4 mRNA | increases expression | 18301758
|
| D014635 |
Valproic Acid |
[Hydralazine co-treated with Valproic Acid] results in increased expression of CASC4 mRNA | affects cotreatment|increases expression | 17183730
|
| Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
|---|
| MESH:D000014 |
Abnormalities, Drug-Induced |
|
Valproic Acid |
4.11 | 8875741 |
| MESH:D000015 |
Abnormalities, Multiple |
|
Valproic Acid |
4.35 | 19490988 |
| MESH:D055371 |
Acute Lung Injury |
|
pirinixic acid |
3.58 | 18653653 |
| MESH:D018248 |
Adenoma, Liver Cell |
|
pirinixic acid |
4.11 | 16434500 |
| MESH:D000550 |
Amblyopia |
|
Valproic Acid |
5.96 | 17688650 |
| MESH:D001008 |
Anxiety Disorders |
|
Valproic Acid |
3.90 | 17497229 |
| MESH:D001321 |
Autistic Disorder |
|
Valproic Acid |
1.98 | 18177632 18558336 17688650 17507914 18775368 19232924 16609825 19460635 17157402 18940202 18316065 20603192 15238991 18985861 18396377 |
| MESH:D001714 |
Bipolar Disorder |
|
Valproic Acid |
3.24 | 20046352 17594078 |
| MESH:D001778 |
Blood Coagulation Disorders |
|
pirinixic acid |
3.57 | 19483382 |
| MESH:D001848 |
Bone Diseases, Developmental |
|
Valproic Acid |
3.63 | 8888407 |
| MESH:D002659 |
Child Development Disorders, Pervasive |
|
Valproic Acid |
2.82 | 20734317 |
| MESH:D002779 |
Cholestasis |
|
pirinixic acid |
3.12 | 19176532 |
| MESH:D019465 |
Craniofacial Abnormalities |
|
Valproic Acid |
1.91 | 8888407 17688650 16575769 |
| MESH:D003876 |
Dermatitis, Atopic |
|
pirinixic acid |
2.57 | 18249437 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
Valproic Acid |
2.25 | 19641884 1733752 |
| MESH:D004421 |
Dystonia |
|
Valproic Acid |
4.51 | 1851702 |
| MESH:D004487 |
Edema |
|
pirinixic acid |
2.90 | 12083418 |
| MESH:D004831 |
Epilepsies, Myoclonic |
|
Valproic Acid |
4.71 | 3659116 17275665 |
| MESH:D004828 |
Epilepsies, Partial |
|
Valproic Acid |
4.64 | 16628512 3922381 |
| MESH:D004827 |
Epilepsy |
|
Valproic Acid |
3.11 | 18234410 20417680 |
| MESH:D004832 |
Epilepsy, Absence |
|
Valproic Acid |
3.96 | 7562514 6426943 6254150 |
| MESH:D017029 |
Epilepsy, Complex Partial |
|
Valproic Acid |
4.86 | 7750514 |
| MESH:D004830 |
Epilepsy, Tonic-Clonic |
|
Valproic Acid |
4.69 | 3659116 |
| MESH:D005234 |
Fatty Liver |
|
pirinixic acid |
9.17 | 20131406 19236843 |
| MESH:D005234 |
Fatty Liver |
|
Valproic Acid |
9.17 | 19224547 14986274 |
| MESH:D005315 |
Fetal Diseases |
|
Valproic Acid |
5.61 | 16575769 |
| MESH:D005317 |
Fetal Growth Retardation |
|
Valproic Acid |
4.64 | 8888407 18558336 |
| MESH:D006333 |
Heart Failure |
|
pirinixic acid |
2.76 | 20558911 |
| MESH:D006529 |
Hepatomegaly |
|
pirinixic acid |
3.55 | 16221962 18467677 19772884 19176532 |
| MESH:D006849 |
Hydrocephalus |
|
Valproic Acid |
5.50 | 17688650 |
| MESH:D006943 |
Hyperglycemia |
|
pirinixic acid |
3.58 | 20558911 |
| MESH:D046110 |
Hypertension, Pregnancy-Induced |
|
Hydralazine |
5.19 | 16612254 |
| MESH:D007333 |
Insulin Resistance |
|
pirinixic acid |
2.87 | 16306350 |
| MESH:D015470 |
Leukemia, Myeloid, Acute |
|
Valproic Acid |
2.20 | 16294345 17596541 |
| MESH:D008106 |
Liver Cirrhosis, Experimental |
|
pirinixic acid |
1.35 | 15474484 |
| MESH:D008113 |
Liver Neoplasms |
|
pirinixic acid |
1.93 | 16377806 15890375 20007298 |
| MESH:D017563 |
Lung Diseases, Interstitial |
|
Valproic Acid |
4.98 | 17228818 |
| MESH:D008881 |
Migraine Disorders |
|
Valproic Acid |
3.47 | 18765137 18803445 |
| MESH:D009135 |
Muscular Diseases |
|
pirinixic acid |
4.07 | 16239165 |
| MESH:D009139 |
Musculoskeletal Abnormalities |
|
Valproic Acid |
4.45 | 8888407 |
| MESH:D009190 |
Myelodysplastic Syndromes |
|
Valproic Acid |
3.35 | 17596541 |
| MESH:D009203 |
Myocardial Infarction |
|
pirinixic acid |
2.27 | 19151258 |
| MESH:D015428 |
Myocardial Reperfusion Injury |
|
pirinixic acid |
3.25 | 16411023 |
| MESH:D009369 |
Neoplasms |
|
pirinixic acid |
2.11 | 17405874 |
| MESH:D009436 |
Neural Tube Defects |
|
Valproic Acid |
3.37 | 16359493 8888407 |
| MESH:D009765 |
Obesity |
|
pirinixic acid |
1.88 | 20558911 |
| MESH:D011297 |
Prenatal Exposure Delayed Effects |
|
Valproic Acid |
4.46 | 20603192 |
| MESH:D019310 |
Pseudolymphoma |
|
Valproic Acid |
5.26 | 12752131 11422049 |
| MESH:D015427 |
Reperfusion Injury |
|
pirinixic acid |
2.55 | 19058328 |
| MESH:D012208 |
Rhabdomyosarcoma |
|
Valproic Acid |
4.64 | 19155313 |
| MESH:D012559 |
Schizophrenia |
|
Valproic Acid |
2.10 | 15737665 19110320 |
| MESH:D012640 |
Seizures |
|
Valproic Acid |
2.99 | 16876388 11738929 11044598 15475178 14763951 17978042 3137016 1511512 |
| MESH:D016135 |
Spinal Dysraphism |
|
Valproic Acid |
4.09 | 19490988 |
| MESH:D013226 |
Status Epilepticus |
|
Valproic Acid |
5.26 | 12833885 |
| MESH:D014178 |
Translocation, Genetic |
|
Valproic Acid |
5.96 | 17262798 |
| MESH:D020194 |
Unverricht-Lundborg Syndrome |
|
Valproic Acid |
5.15 | 3119515 |
| MESH:D014564 |
Urogenital Abnormalities |
|
Valproic Acid |
5.20 | 8888407 |
Related Pathway Information