AutismKB 2.0

Annotation Detail for CTRC


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Basic Information Top
Gene Symbol:CTRC ( CLCR,ELA4 )
Gene Full Name: chymotrypsin C (caldecrin)
Band: 1p36.21
Quick LinksEntrez ID:11330; OMIM: 601405; Uniprot ID:CTRC_HUMAN; ENSEMBL ID: ENSG00000162438; HGNC ID: 2523
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1932Pancreatitis
No data
No data
Desease Name
Pancreatitis, chronic, susceptibility to
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000643 Ammonium Chloride Ammonium Chloride affects the expression of CTRC mRNAaffects expression 16483693
C095105 bexarotene bexarotene results in increased expression of CTRC mRNAincreases expression 16648578
C006253 pirinixic acid pirinixic acid results in increased expression of CTRC mRNAincreases expression 17426115
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000138 Acidosis Ammonium Chloride 4.3018287403
MESH:D055371 Acute Lung Injury pirinixic acid 3.6418653653
MESH:D018248 Adenoma, Liver Cell pirinixic acid 4.2216434500
MESH:D001778 Blood Coagulation Disorders pirinixic acid 3.6319483382
MESH:D001943 Breast Neoplasms bexarotene 2.9516344269 16818667
MESH:D002289 Carcinoma, Non-Small-Cell Lung bexarotene 3.3416247446
MESH:D002779 Cholestasis pirinixic acid 3.1519176532
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.5918249437
MESH:D004487 Edema pirinixic acid 2.9612083418
MESH:D005234 Fatty Liver pirinixic acid 3.2519236843 20131406
MESH:D006333 Heart Failure pirinixic acid 2.7820558911
MESH:D006529 Hepatomegaly pirinixic acid 3.6419772884 19176532 16221962 18467677
MESH:D006943 Hyperglycemia pirinixic acid 3.6320558911
MESH:D007333 Insulin Resistance pirinixic acid 2.9016306350
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 1.3515474484
MESH:D008113 Liver Neoplasms pirinixic acid 1.9415890375 20007298 16377806
MESH:D008175 Lung Neoplasms bexarotene 2.5317849452
MESH:D016410 Lymphoma, T-Cell, Cutaneous bexarotene 5.8011161223
MESH:D008325 Mammary Neoplasms, Experimental bexarotene 3.6715591091 19196723 19196722
MESH:D009135 Muscular Diseases pirinixic acid 4.1616239165
MESH:D009203 Myocardial Infarction pirinixic acid 2.2919151258
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 3.2916411023
MESH:D009369 Neoplasms pirinixic acid 2.1217405874
MESH:D009376 Neoplasms, Hormone-Dependent bexarotene 5.6519196722
MESH:D009765 Obesity pirinixic acid 1.8920558911
MESH:D050500 Pancreatitis, Chronic marker/mechanism 18059268
OMIM:167800 PANCREATITIS, HEREDITARY marker/mechanism
MESH:D015427 Reperfusion Injury pirinixic acid 2.5619058328
No data
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA27024
    • No data
    Releated disease ID Related disease Name
    PA445220Pancreatitis
    No data
    Drug Bank Top

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    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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