Annotation Detail for CYGB
Basic Information Top
| Gene Symbol: | CYGB ( HGB,STAP ) |
|---|---|
| Gene Full Name: | cytoglobin |
| Band: | 17q25.1 |
| Quick Links | Entrez ID:114757; OMIM: 608759; Uniprot ID:CYGB_HUMAN; ENSEMBL ID: ENSG00000161544; HGNC ID: 16505 |
| Relate to Another Database: | SFARIGene; denovo-db |
Related Pathway Information| Chemical ID | Chemical Name | Interaction | Interaction Action | Publication |
|---|---|---|---|---|
| C548651 | 2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester | 2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester results in increased expression of CYGB mRNA | increases expression | 19933214 |
| D000082 | Acetaminophen | Acetaminophen affects the expression of CYGB mRNA | affects expression | 17562736 |
| D016604 | Aflatoxin B1 | Aflatoxin B1 affects the expression of CYGB protein | affects expression | 20106945 |
| D000643 | Ammonium Chloride | Ammonium Chloride affects the expression of CYGB mRNA | affects expression | 16483693 |
| D016718 | Arachidonic Acid | CYGB protein inhibits the reaction [[ferric nitrilotriacetate co-treated with Arachidonic Acid] results in increased expression of TGFB1 mRNA] | affects cotreatment|decreases reaction|increases expression | 16581302 |
| D016718 | Arachidonic Acid | CYGB protein inhibits the reaction [[ferric nitrilotriacetate co-treated with Arachidonic Acid] results in increased expression of TIMP1 mRNA] | affects cotreatment|decreases reaction|increases expression | 16581302 |
| D016718 | Arachidonic Acid | CYGB protein results in decreased susceptibility to [ferric nitrilotriacetate co-treated with Arachidonic Acid] | affects cotreatment|decreases response to substance | 16581302 |
| D019324 | beta-Naphthoflavone | [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CYGB mRNA | affects cotreatment|increases expression | 18164116 |
| D001564 | Benzo(a)pyrene | Benzo(a)pyrene results in increased expression of CYGB mRNA | increases expression | 20106945 20064835 |
| D002251 | Carbon Tetrachloride | CYGB protein inhibits the reaction [Carbon Tetrachloride results in increased expression of ACTA2 protein] | decreases reaction|increases expression | 16581302 |
| D002251 | Carbon Tetrachloride | CYGB protein inhibits the reaction [Carbon Tetrachloride results in increased expression of TGFB1 mRNA] | decreases reaction|increases expression | 16581302 |
| D002251 | Carbon Tetrachloride | CYGB protein inhibits the reaction [Carbon Tetrachloride results in increased expression of TGFB1 protein] | decreases reaction|increases expression | 16581302 |
| D002251 | Carbon Tetrachloride | CYGB protein inhibits the reaction [Carbon Tetrachloride results in increased expression of TIMP1 mRNA] | decreases reaction|increases expression | 16581302 |
| D003545 | Cysteine | Cysteine inhibits the reaction [Thioacetamide results in increased expression of CYGB protein] | decreases reaction|increases expression | 15158331 |
| D004052 | Diethylnitrosamine | [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CYGB mRNA | affects cotreatment|increases expression | 18164116 |
| C074283 | estradiol 3-benzoate | estradiol 3-benzoate promotes the reaction [Thioacetamide results in increased expression of CYGB mRNA] | increases expression|increases reaction | 15716488 |
| D004997 | Ethinyl Estradiol | Ethinyl Estradiol results in increased expression of CYGB mRNA | increases expression | 17942748 |
| D004997 | Ethinyl Estradiol | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of CYGB mRNA | affects cotreatment|increases expression | 17942748 |
| D004997 | Ethinyl Estradiol | Ethinyl Estradiol results in decreased expression of CYGB mRNA | decreases expression | 17557909 |
| C020326 | ferric nitrilotriacetate | CYGB protein inhibits the reaction [[ferric nitrilotriacetate co-treated with Arachidonic Acid] results in increased expression of TGFB1 mRNA] | affects cotreatment|decreases reaction|increases expression | 16581302 |
| C020326 | ferric nitrilotriacetate | CYGB protein inhibits the reaction [[ferric nitrilotriacetate co-treated with Arachidonic Acid] results in increased expression of TIMP1 mRNA] | affects cotreatment|decreases reaction|increases expression | 16581302 |
| C020326 | ferric nitrilotriacetate | CYGB protein results in decreased susceptibility to [ferric nitrilotriacetate co-treated with Arachidonic Acid] | affects cotreatment|decreases response to substance | 16581302 |
| D005419 | Flavonoids | Flavonoids results in increased expression of CYGB mRNA | increases expression | 18035473 |
| C010176 | halofuginone | halofuginone inhibits the reaction [Thioacetamide results in increased expression of CYGB mRNA] | decreases reaction|increases expression | 17180598 |
| C010176 | halofuginone | halofuginone inhibits the reaction [Thioacetamide results in increased expression of CYGB protein] | decreases reaction|increases expression | 17180598 |
| C010176 | halofuginone | halofuginone results in increased expression of CYGB mRNA | increases expression | 17180598 |
| D006861 | Hydrogen Peroxide | CYGB protein results in increased metabolism of Hydrogen Peroxide | increases metabolic processing | 11320098 |
| C078038 | inchinko-to | inchinko-to inhibits the reaction [Thioacetamide results in increased expression of CYGB protein] | decreases reaction|increases expression | 15288473 |
| C008285 | linoleic acid hydroperoxide | CYGB protein results in increased metabolism of linoleic acid hydroperoxide | increases metabolic processing | 11320098 |
| D008715 | Methionine | Methionine inhibits the reaction [Thioacetamide results in increased expression of CYGB protein] | decreases reaction|increases expression | 15158331 |
| D013749 | Tetrachlorodibenzodioxin | Tetrachlorodibenzodioxin results in increased expression of CYGB mRNA | increases expression | 20106945 |
| D013749 | Tetrachlorodibenzodioxin | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of CYGB mRNA | affects cotreatment|increases expression | 17942748 |
| D013749 | Tetrachlorodibenzodioxin | Tetrachlorodibenzodioxin results in increased expression of CYGB mRNA | increases expression | 19933214 |
| D013853 | Thioacetamide | Cysteine inhibits the reaction [Thioacetamide results in increased expression of CYGB protein] | decreases reaction|increases expression | 15158331 |
| D013853 | Thioacetamide | estradiol 3-benzoate promotes the reaction [Thioacetamide results in increased expression of CYGB mRNA] | increases expression|increases reaction | 15716488 |
| D013853 | Thioacetamide | halofuginone inhibits the reaction [Thioacetamide results in increased expression of CYGB mRNA] | decreases reaction|increases expression | 17180598 |
| D013853 | Thioacetamide | halofuginone inhibits the reaction [Thioacetamide results in increased expression of CYGB protein] | decreases reaction|increases expression | 17180598 |
| D013853 | Thioacetamide | inchinko-to inhibits the reaction [Thioacetamide results in increased expression of CYGB protein] | decreases reaction|increases expression | 15288473 |
| D013853 | Thioacetamide | Methionine inhibits the reaction [Thioacetamide results in increased expression of CYGB protein] | decreases reaction|increases expression | 15158331 |
| D013853 | Thioacetamide | Thioacetamide results in increased expression of CYGB mRNA | increases expression | 17180598 11320098 15716488 |
| D013853 | Thioacetamide | Thioacetamide results in increased expression of CYGB protein | increases expression | 15158331 11320098 15288473 17180598 |
| Disease ID | Disease Name | Direct Evidence | Inference Chemical Name | Inference Score | Publication |
|---|---|---|---|---|---|
| MESH:D000014 | Abnormalities, Drug-Induced | Tetrachlorodibenzodioxin | 2.74 | 15322242 11752688 14514962 | |
| MESH:D000138 | Acidosis | Ammonium Chloride | 3.45 | 18287403 | |
| MESH:D000152 | Acne Vulgaris | Ethinyl Estradiol | 3.84 | 17505938 | |
| MESH:D000230 | Adenocarcinoma | Benzo(a)pyrene | 4.08 | 20127859 20464547 | |
| MESH:D000230 | Adenocarcinoma | Ethinyl Estradiol | 4.08 | 14692618 | |
| MESH:D000236 | Adenoma | Benzo(a)pyrene | 10.84 | 6695378 | |
| MESH:D000236 | Adenoma | beta-Naphthoflavone | 10.84 | 19389873 | |
| MESH:D000236 | Adenoma | Diethylnitrosamine | 10.84 | 6695378 10737359 | |
| MESH:D018248 | Adenoma, Liver Cell | Diethylnitrosamine | 9.69 | 19061943 19052882 17620307 16434500 18056438 17162532 | |
| MESH:D018248 | Adenoma, Liver Cell | Tetrachlorodibenzodioxin | 9.69 | 16835633 | |
| MESH:D000740 | Anemia | Tetrachlorodibenzodioxin | 2.85 | 11748828 | |
| MESH:D000799 | Angioedema | Acetaminophen | 3.74 | 10982225 | |
| MESH:D017544 | Aortic Aneurysm, Abdominal | Benzo(a)pyrene | 3.96 | 19183758 | |
| MESH:D001161 | Arteriosclerosis | Ethinyl Estradiol | 3.36 | 11256880 | |
| MESH:D001169 | Arthritis, Experimental | Ethinyl Estradiol | 2.60 | 15885639 | |
| MESH:D001321 | Autistic Disorder | Acetaminophen | 2.85 | 18445737 | |
| MESH:D001321 | Autistic Disorder | Arachidonic Acid | 2.85 | 18582451 | |
| MESH:D001321 | Autistic Disorder | Cysteine | 2.85 | 16917939 19056591 19267885 | |
| MESH:D001321 | Autistic Disorder | Methionine | 2.85 | 16917939 19056591 19267885 | |
| MESH:D001778 | Blood Coagulation Disorders | Tetrachlorodibenzodioxin | 8.81 | 12125929 | |
| MESH:D001778 | Blood Coagulation Disorders | Thioacetamide | 8.81 | 19483382 | |
| MESH:D001836 | Body Weight Changes | Tetrachlorodibenzodioxin | 3.69 | 15340226 | |
| MESH:D001848 | Bone Diseases, Developmental | Tetrachlorodibenzodioxin | 2.69 | 15746008 | |
| MESH:D001943 | Breast Neoplasms | Benzo(a)pyrene | 1.80 | 20146248 17474063 | |
| MESH:D001943 | Breast Neoplasms | Diethylnitrosamine | 1.80 | 17474063 | |
| MESH:D001943 | Breast Neoplasms | Tetrachlorodibenzodioxin | 1.80 | 20435547 | |
| MESH:D002252 | Carbon Tetrachloride Poisoning | Carbon Tetrachloride | 3.67 | 16050911 16227642 15721981 15673190 16192424 3786805 15700767 16011737 18705752 16124888 16097048 10355542 | |
| MESH:D002277 | Carcinoma | Tetrachlorodibenzodioxin | 2.71 | 16835633 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Acetaminophen | 8.69 | 3084413 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Aflatoxin B1 | 8.69 | 12907637 12619106 21507988 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Carbon Tetrachloride | 8.69 | 18788625 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Diethylnitrosamine | 8.69 | 19107877 19208518 16830150 16935385 20512989 19052882 19383236 10672840 16540662 20214788 20935162 16502159 20007298 19171122 17428255 16288022 20524982 11831363 20101231 17138121 16698587 19822196 18494052 3084413 18978308 19701751 19335982 17761372 19394651 20514400 3581430 18210153 20084675 17978847 19519916 18506893 17162532 19539802 16807293 17173139 18785209 16328049 18665156 16569478 18056438 16779866 18788625 20727157 19418558 18393292 16878318 21159647 20432363 17055752 19919837 10737359 16681979 18971187 18691550 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Thioacetamide | 8.69 | 17997003 | |
| MESH:D002292 | Carcinoma, Renal Cell | ferric nitrilotriacetate | 4.32 | 8340253 | |
| MESH:D002294 | Carcinoma, Squamous Cell | Benzo(a)pyrene | 2.02 | 20419170 | |
| MESH:D006332 | Cardiomegaly | Tetrachlorodibenzodioxin | 2.31 | 16120746 18670907 18850075 | |
| MESH:D002318 | Cardiovascular Diseases | Hydrogen Peroxide | 3.44 | 16936243 | |
| MESH:D002386 | Cataract | Acetaminophen | 2.52 | 10977129 | |
| MESH:D002471 | Cell Transformation, Neoplastic | Diethylnitrosamine | 2.78 | 17174075 2727394 7505956 21159647 | |
| MESH:D002659 | Child Development Disorders, Pervasive | Methionine | 4.28 | 19267885 | |
| MESH:D018281 | Cholangiocarcinoma | Diethylnitrosamine | 15.57 | 19052882 | |
| MESH:D018281 | Cholangiocarcinoma | Tetrachlorodibenzodioxin | 15.57 | 16835633 | |
| MESH:D018281 | Cholangiocarcinoma | Thioacetamide | 15.57 | 18291259 | |
| MESH:D002779 | Cholestasis | Ethinyl Estradiol | 2.79 | 16919318 17333356 16105132 17110522 17681005 15861022 11677210 | |
| MESH:D002972 | Cleft Palate | Tetrachlorodibenzodioxin | 2.06 | 16354765 12621046 8697196 15668235 15340226 | |
| MESH:D000013 | Congenital Abnormalities | Tetrachlorodibenzodioxin | 2.96 | 17141729 14669216 | |
| MESH:D019465 | Craniofacial Abnormalities | Tetrachlorodibenzodioxin | 1.25 | 15322242 10048152 20055451 | |
| MESH:D003924 | Diabetes Mellitus, Type 2 | Diethylnitrosamine | 4.13 | 20387270 | |
| MESH:D003924 | Diabetes Mellitus, Type 2 | Tetrachlorodibenzodioxin | 4.13 | 17107852 | |
| MESH:D056486 | Drug-Induced Liver Injury | Acetaminophen | 11.67 | 16109766 12594235 17906064 12153990 12705907 12540782 18071297 16485898 19085960 11834606 15968718 18713872 16177239 14986274 11421492 16227642 10915739 17562736 17522070 10774834 11287661 12958197 16081117 19420014 19416960 15619225 19739265 19164858 11461765 11739529 14725611 11743745 16781746 10663392 2444490 19370779 12392966 16393943 14550746 19923254 11529661 | |
| MESH:D056486 | Drug-Induced Liver Injury | Carbon Tetrachloride | 11.67 | 9327722 7120509 11566570 3786805 15968718 10092053 19336974 15998439 2869522 10915739 4309450 3732212 16227642 7179309 17522070 6884620 19085960 21278145 7440962 6623471 16177239 15027814 | |
| MESH:D056486 | Drug-Induced Liver Injury | Diethylnitrosamine | 11.67 | 19107877 | |
| MESH:D056486 | Drug-Induced Liver Injury | Tetrachlorodibenzodioxin | 11.67 | 20420201 | |
| MESH:D056486 | Drug-Induced Liver Injury | Thioacetamide | 11.67 | 12963478 | |
| MESH:D056487 | Drug-Induced Liver Injury, Chronic | Acetaminophen | 3.99 | 19426721 | |
| MESH:D004362 | Drug Toxicity | Tetrachlorodibenzodioxin | 2.68 | 11462148 | |
| MESH:D004487 | Edema | Arachidonic Acid | 6.78 | 9599246 15177302 9831321 16716910 7990266 11698051 | |
| MESH:D004487 | Edema | Tetrachlorodibenzodioxin | 6.78 | 11000095 12711302 | |
| MESH:D004489 | Edema, Cardiac | Tetrachlorodibenzodioxin | 3.80 | 18230668 15322242 16714409 | |
| MESH:D004681 | Encephalomyelitis, Autoimmune, Experimental | Ethinyl Estradiol | 3.08 | 12538720 | |
| MESH:D004715 | Endometriosis | Tetrachlorodibenzodioxin | 2.92 | 10568697 9294722 | |
| MESH:D004931 | Esophageal Achalasia | Diethylnitrosamine | 5.01 | 16302075 | |
| MESH:D004938 | Esophageal Neoplasms | Benzo(a)pyrene | 1.98 | 16530937 | |
| MESH:D005124 | Eye Abnormalities | Tetrachlorodibenzodioxin | 2.93 | 11564622 | |
| MESH:D005218 | Fat Necrosis | Thioacetamide | 5.61 | 16456712 | |
| MESH:D005234 | Fatty Liver | Carbon Tetrachloride | 12.51 | 12631006 17595544 16239168 19224547 15959796 61145 12795759 16045604 | |
| MESH:D005234 | Fatty Liver | Diethylnitrosamine | 12.51 | 20387270 21071580 | |
| MESH:D005234 | Fatty Liver | Ethinyl Estradiol | 12.51 | 15345470 | |
| MESH:D005313 | Fetal Death | Tetrachlorodibenzodioxin | 3.35 | 11858732 | |
| MESH:D005334 | Fever | Arachidonic Acid | 4.56 | 11852909 | |
| MESH:D005355 | Fibrosis | Carbon Tetrachloride | 8.23 | 18705752 | |
| MESH:D005355 | Fibrosis | Tetrachlorodibenzodioxin | 8.23 | 20067830 | |
| MESH:D005756 | Gastritis | Acetaminophen | 3.57 | 16983495 | |
| MESH:D006058 | Gonadal Disorders | Tetrachlorodibenzodioxin | 4.49 | 10696789 | |
| MESH:D006330 | Heart Defects, Congenital | Benzo(a)pyrene | 6.26 | 20471113 | |
| MESH:D006330 | Heart Defects, Congenital | Tetrachlorodibenzodioxin | 6.26 | 11294989 10048152 | |
| MESH:D006470 | Hemorrhage | Tetrachlorodibenzodioxin | 3.23 | 11000095 | |
| MESH:D006501 | Hepatic Encephalopathy | Thioacetamide | 4.47 | 18665440 17276928 15929193 | |
| MESH:D006505 | Hepatitis | Carbon Tetrachloride | 9.12 | 19900420 19110552 | |
| MESH:D006505 | Hepatitis | Thioacetamide | 9.12 | 16456712 | |
| MESH:D006529 | Hepatomegaly | Tetrachlorodibenzodioxin | 2.78 | 16120746 15340226 12621046 | |
| MESH:D020271 | Heredodegenerative Disorders, Nervous System | marker/mechanism | 16825958 | ||
| MESH:D006869 | Hydronephrosis | Tetrachlorodibenzodioxin | 3.94 | 18606429 15340226 16354765 8697196 16959395 | |
| MESH:D006930 | Hyperalgesia | Acetaminophen | 2.61 | 16870215 | |
| MESH:D006932 | Hyperbilirubinemia | Carbon Tetrachloride | 4.42 | 16899240 | |
| MESH:D006965 | Hyperplasia | halofuginone | 5.14 | 11874485 | |
| MESH:D006973 | Hypertension | Tetrachlorodibenzodioxin | 1.87 | 18670907 18850075 | |
| MESH:D006975 | Hypertension, Portal | Carbon Tetrachloride | 3.98 | 15338365 | |
| MESH:D007021 | Hypospadias | Ethinyl Estradiol | 3.70 | 16945680 16569931 | |
| MESH:D007247 | Infertility, Female | Ethinyl Estradiol | 3.36 | 12013081 | |
| MESH:D007248 | Infertility, Male | Ethinyl Estradiol | 2.41 | 17937319 | |
| MESH:D007249 | Inflammation | Arachidonic Acid | 11.54 | 15177302 17371808 9831321 | |
| MESH:D007249 | Inflammation | Diethylnitrosamine | 11.54 | 18785209 | |
| MESH:D007249 | Inflammation | Flavonoids | 11.54 | 17296493 | |
| MESH:D007249 | Inflammation | Tetrachlorodibenzodioxin | 11.54 | 12200463 12878042 | |
| MESH:D007569 | Jaw Abnormalities | Tetrachlorodibenzodioxin | 3.23 | 16580747 | |
| MESH:D007674 | Kidney Diseases | Acetaminophen | 6.29 | 12587719 15629191 | |
| MESH:D007674 | Kidney Diseases | ferric nitrilotriacetate | 6.29 | 15834431 18617210 | |
| MESH:D007676 | Kidney Failure, Chronic | Hydrogen Peroxide | 4.17 | 16518626 | |
| MESH:D007680 | Kidney Neoplasms | ferric nitrilotriacetate | 4.57 | 9667754 18055543 | |
| MESH:D008103 | Liver Cirrhosis | Carbon Tetrachloride | 10.83 | 17174718 11903743 21278145 16239168 17334410 16221502 11408273 17157831 16943688 | |
| MESH:D008103 | Liver Cirrhosis | Diethylnitrosamine | 10.83 | 18665156 18522880 19638242 20032147 18407596 | |
| MESH:D008103 | Liver Cirrhosis | halofuginone | 10.83 | 17180598 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | therapeutic | 16581302 | ||
| MESH:D008106 | Liver Cirrhosis, Experimental | Carbon Tetrachloride | 10.74 | 12649538 18481824 15818738 18166357 15931870 20821823 12666154 11481614 15730626 12586293 15925388 14724832 17698563 15650968 18395095 15893842 15959796 18429990 17869086 16097048 14716496 16033810 14512876 15996030 17481882 12958196 15052691 17900296 18472332 10355542 17976157 17565644 14716833 15362042 18472094 18339082 12389079 16027843 17714472 18705752 12609069 15057751 18251166 17721639 16638106 16116963 17922224 18279442 16136751 18317297 18263696 17944888 14620537 18205269 18277467 15123356 16011737 12741479 16015684 17631135 18420326 16192424 15673190 12667390 14748882 18156304 18054572 17640975 12445418 17805973 17761835 17525996 17708605 18412020 17823541 18418968 18006644 15338365 15370692 12445421 18376398 17766677 12898905 12546737 16248980 12632512 18187930 18210741 18395914 15876570 17557913 12632514 13678700 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | Cysteine | 10.74 | 15158331 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | halofuginone | 10.74 | 11172339 14739098 18458672 16489207 12175628 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | inchinko-to | 10.74 | 15288473 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | Methionine | 10.74 | 15158331 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | Tetrachlorodibenzodioxin | 10.74 | 12878042 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | Thioacetamide | 10.74 | 15334695 11172339 15465738 16126171 18416461 11682029 16098781 15474484 11481614 18295389 15288473 17629604 15075984 18380797 12531686 15095483 16489207 15078482 12557150 18395095 12175628 15158331 16511523 16343077 15362042 18032466 18615449 15288472 12679928 17355460 17050028 15716488 14739098 17127702 12891558 15316131 18606216 18263696 10677585 17292413 16097051 12085344 18031379 16248980 18458672 | |
| MESH:D008107 | Liver Diseases | Acetaminophen | 9.16 | 16611625 12587719 12969438 11587558 16610002 19460945 19784758 19014921 | |
| MESH:D008107 | Liver Diseases | Carbon Tetrachloride | 9.16 | 16964402 16246199 15720792 15830285 17285989 | |
| MESH:D008107 | Liver Diseases | Diethylnitrosamine | 9.16 | 17034775 | |
| MESH:D008107 | Liver Diseases | Thioacetamide | 9.16 | 18374380 15158337 16337175 | |
| MESH:D017093 | Liver Failure | Carbon Tetrachloride | 4.05 | 15123358 | |
| MESH:D017114 | Liver Failure, Acute | Acetaminophen | 15.68 | 16871587 17185352 | |
| MESH:D017114 | Liver Failure, Acute | Carbon Tetrachloride | 15.68 | 14706259 16899240 | |
| MESH:D017114 | Liver Failure, Acute | Thioacetamide | 15.68 | 12479984 15633222 17276928 15313186 | |
| MESH:D008113 | Liver Neoplasms | Aflatoxin B1 | 17.45 | 9163691 15890375 18177683 2125692 | |
| MESH:D008113 | Liver Neoplasms | Benzo(a)pyrene | 17.45 | 21137059 20195826 | |
| MESH:D008113 | Liver Neoplasms | beta-Naphthoflavone | 17.45 | 21295105 19389873 | |
| MESH:D008113 | Liver Neoplasms | Carbon Tetrachloride | 17.45 | 19294768 | |
| MESH:D008113 | Liver Neoplasms | Diethylnitrosamine | 17.45 | 2422723 12112319 20501860 18648771 21071580 19638242 20118626 20452335 18978307 19427195 2862719 12771043 19090486 19254457 19642983 19294768 19551842 19426721 21047994 21278145 19996281 15175105 16942905 18977376 19256749 19073162 19833225 20101389 20434301 20137499 9163691 19499222 19850985 19812893 15885732 19690152 20583210 18644402 20492335 18754104 10737359 21167192 20405173 19255062 | |
| MESH:D008113 | Liver Neoplasms | Tetrachlorodibenzodioxin | 17.45 | 16984957 | |
| MESH:D008114 | Liver Neoplasms, Experimental | Aflatoxin B1 | 17.92 | 8603461 | |
| MESH:D008114 | Liver Neoplasms, Experimental | beta-Naphthoflavone | 17.92 | 18164116 | |
| MESH:D008114 | Liver Neoplasms, Experimental | Carbon Tetrachloride | 17.92 | 12014681 15583823 | |
| MESH:D008114 | Liver Neoplasms, Experimental | Diethylnitrosamine | 17.92 | 3124819 18775883 17854601 18253720 19519916 18164116 19126423 18544905 18093689 18079962 16842330 19539802 18282651 17174075 21159647 19009564 17942915 19004024 18308698 2563599 16267830 9362446 | |
| MESH:D008114 | Liver Neoplasms, Experimental | Tetrachlorodibenzodioxin | 17.92 | 12151625 | |
| MESH:D008175 | Lung Neoplasms | Aflatoxin B1 | 4.72 | 14755239 | |
| MESH:D008175 | Lung Neoplasms | Benzo(a)pyrene | 4.72 | 6695378 20869020 18816296 18520028 20135361 17053015 20464547 20064080 18569708 | |
| MESH:D008175 | Lung Neoplasms | Diethylnitrosamine | 4.72 | 21163286 20970405 6695378 20512841 | |
| MESH:D008175 | Lung Neoplasms | Tetrachlorodibenzodioxin | 4.72 | 11884234 19555203 | |
| MESH:D008325 | Mammary Neoplasms, Experimental | estradiol 3-benzoate | 4.22 | 15375486 | |
| MESH:D008546 | Melanoma, Experimental | Acetaminophen | 3.46 | 19513568 | |
| MESH:D009062 | Mouth Neoplasms | Benzo(a)pyrene | 3.10 | 16381670 | |
| MESH:D017202 | Myocardial Ischemia | Tetrachlorodibenzodioxin | 2.93 | 12213967 | |
| MESH:D009362 | Neoplasm Metastasis | Diethylnitrosamine | 2.52 | 3581430 9029167 | |
| MESH:D009369 | Neoplasms | Benzo(a)pyrene | 2.12 | 11141357 | |
| MESH:D009421 | Nervous System Malformations | Tetrachlorodibenzodioxin | 3.11 | 14600291 | |
| MESH:D019636 | Neurodegenerative Diseases | Acetaminophen | 7.88 | 18514411 | |
| MESH:D019636 | Neurodegenerative Diseases | Diethylnitrosamine | 7.88 | 20387270 | |
| MESH:D009461 | Neurologic Manifestations | Diethylnitrosamine | 5.01 | 20387270 | |
| MESH:D010146 | Pain | Acetaminophen | 2.30 | 16870215 | |
| MESH:D010190 | Pancreatic Neoplasms | Diethylnitrosamine | 2.38 | 16540662 | |
| MESH:D016584 | Panic Disorder | Ethinyl Estradiol | 3.58 | 11578682 | |
| MESH:D010212 | Papilloma | Hydrogen Peroxide | 3.98 | 12065085 | |
| MESH:D010382 | Peliosis Hepatis | Tetrachlorodibenzodioxin | 4.14 | 12520081 | |
| MESH:D017119 | Porphyria Cutanea Tarda | Tetrachlorodibenzodioxin | 3.45 | 18163543 | |
| MESH:D011230 | Precancerous Conditions | Diethylnitrosamine | 3.46 | 2563599 | |
| MESH:D011297 | Prenatal Exposure Delayed Effects | Tetrachlorodibenzodioxin | 3.08 | 11399792 11222880 11896295 11118676 | |
| MESH:D011471 | Prostatic Neoplasms | Benzo(a)pyrene | 3.00 | 17292933 | |
| MESH:D011537 | Pruritus | Ethinyl Estradiol | 3.20 | 16919318 15861022 | |
| MESH:D015619 | Respiratory System Abnormalities | Tetrachlorodibenzodioxin | 3.73 | 18990726 | |
| MESH:D012559 | Schizophrenia | Methionine | 3.66 | 15737665 | |
| MESH:D012871 | Skin Diseases | halofuginone | 3.49 | 11874485 | |
| MESH:D012878 | Skin Neoplasms | Benzo(a)pyrene | 9.15 | 10029692 19755658 | |
| MESH:D012878 | Skin Neoplasms | Hydrogen Peroxide | 9.15 | 12065085 | |
| MESH:D012878 | Skin Neoplasms | Tetrachlorodibenzodioxin | 9.15 | 16192470 | |
| MESH:D013088 | Spermatocele | Ethinyl Estradiol | 3.84 | 16709447 | |
| MESH:D013274 | Stomach Neoplasms | Benzo(a)pyrene | 2.30 | 20155912 2093021 | |
| MESH:D013274 | Stomach Neoplasms | Diethylnitrosamine | 2.30 | 18456281 | |
| MESH:D019851 | Thrombophilia | Ethinyl Estradiol | 3.52 | 11994571 | |
| MESH:D013927 | Thrombosis | Ethinyl Estradiol | 3.06 | 15669648 | |
| MESH:D013959 | Thyroid Diseases | Tetrachlorodibenzodioxin | 3.80 | 12697716 | |
| MESH:D013964 | Thyroid Neoplasms | Diethylnitrosamine | 2.90 | 7505956 | |
| MESH:D001749 | Urinary Bladder Neoplasms | Benzo(a)pyrene | 2.14 | 17053015 | |
| MESH:D014581 | Urticaria | Acetaminophen | 2.87 | 10982225 | |
| MESH:D014594 | Uterine Neoplasms | Ethinyl Estradiol | 3.19 | 14692618 | |
| MESH:D054079 | Vascular Malformations | Tetrachlorodibenzodioxin | 4.49 | 12125929 | |
| MESH:D020246 | Venous Thrombosis | Ethinyl Estradiol | 3.44 | 15869587 14671159 | |
| MESH:D019282 | Wasting Syndrome | Tetrachlorodibenzodioxin | 4.14 | 15886252 |
| No data |