AutismKB 2.0

Annotation Detail for RNF157


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Basic Information Top
Gene Symbol:RNF157 ( - )
Gene Full Name: ring finger protein 157
Band: 17q25.1
Quick LinksEntrez ID:114804; OMIM: NA; Uniprot ID:RN157_HUMAN; ENSEMBL ID: ENSG00000141576; HGNC ID: 29402
Relate to Another Database: SFARIGene; denovo-db
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Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C006632 arsenic trioxide arsenic trioxide results in increased expression of RNF157 mRNAincreases expression 20458559
D008748 Methylcholanthrene Methylcholanthrene results in decreased expression of RNF157 mRNAdecreases expression 20713471
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of RNF157 mRNAincreases expression 19465110
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 3.5911752688 15322242 14514962
MESH:D000230 Adenocarcinoma arsenic trioxide 2.3611798837 19825857
MESH:D000236 Adenoma Methylcholanthrene 3.7210545420 6695378
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 4.1216835633
MESH:D000740 Anemia Tetrachlorodibenzodioxin 3.3911748828
MESH:D050197 Atherosclerosis Methylcholanthrene 3.6911922910
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 10.6216206674
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 10.6212125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 4.6615340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 3.0215746008
MESH:D001943 Breast Neoplasms Methylcholanthrene 2.1717474063
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 2.1720435547
MESH:D002051 Burkitt Lymphoma arsenic trioxide 4.8611589617
MESH:D002277 Carcinoma Methylcholanthrene 9.5710545420
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 9.5716835633
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 1.9816217749 15073043 14691202 15553829 11135700
MESH:D002291 Carcinoma, Papillary arsenic trioxide 5.7419014326
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 4.5712490120
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.5818850075 18670907 16120746
MESH:D002471 Cell Transformation, Neoplastic Methylcholanthrene 3.7916192471
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 3.5816835633
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 2.2516354765 8697196 15668235 12621046 15340226
MESH:D015179 Colorectal Neoplasms arsenic trioxide 1.8720501625
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 3.4814669216 17141729
MESH:D023903 Coronary Restenosis arsenic trioxide 4.7712609071
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 2.5710525206
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 2.5710048152 15322242 20055451
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 4.6315213294
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 1.7417107852
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 1.6220420201
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 3.0911462148
MESH:D004487 Edema Tetrachlorodibenzodioxin 2.8511000095 12711302
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 4.7716714409 18230668 15322242
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 3.479294722 10568697
MESH:D004938 Esophageal Neoplasms arsenic trioxide 2.3912903497
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 3.3411564622
MESH:D005234 Fatty Liver arsenic trioxide 3.7715073043
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 4.1111858732
MESH:D005354 Fibrosarcoma Methylcholanthrene 5.6814633661 10962813
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 3.6020067830
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 4.8516904648
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 5.4610696789
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 2.5311294989 10048152
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.8211000095
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 3.5415340226 12621046 16120746
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 4.9116959395 18606429 8697196 16354765 15340226
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 2.0318850075 18670907
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 2.0412878042 12200463
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 3.8216580747
MESH:D007938 Leukemia arsenic trioxide 3.0115070760
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 4.2812560223 17077332
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 5.0516972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 3.7514633726
MESH:D007951 Leukemia, Myeloid arsenic trioxide 4.2419077051
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 2.1916968895 16467208 17050201 19850784 20471514
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 3.4812712474 11161223 11468182 12018890 16112521 17649720 17712046 15622746 19075265 12679006 15748426 16966277 9834237 17217047 17107899 17869043 16891316 19225113 15213294 16823087 16331271 15336539 19035177 16330433 19642359
MESH:D015458 Leukemia, T-Cell arsenic trioxide 4.9416882451
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 1.2512878042
MESH:D008113 Liver Neoplasms arsenic trioxide 4.8814682389
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 4.8816984957
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 11.4120377131
MESH:D008114 Liver Neoplasms, Experimental Methylcholanthrene 11.41598648 1399818
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 11.4112151625
MESH:D008133 Long QT Syndrome arsenic trioxide 3.6915213294
MESH:D008175 Lung Neoplasms arsenic trioxide 3.6819825857 11798837
MESH:D008175 Lung Neoplasms Methylcholanthrene 3.686695378 16271038 21163286 9230183 16337739 15390079 20512841 7750092 10545420 20970405 17909032 1399818 11893704
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 3.6819555203 11884234
MESH:D009101 Multiple Myeloma arsenic trioxide 3.4119417148 15949261 11468182 19549372 14977855
MESH:D009182 Mycosis Fungoides arsenic trioxide 5.5418349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 3.3616105982 16882451
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 3.3812213967
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 4.5416624393
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 3.8014600291
MESH:D009436 Neural Tube Defects arsenic trioxide 3.3810525206
MESH:D010051 Ovarian Neoplasms arsenic trioxide 2.5112452020 16624393 19769630
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 2.6415580305
MESH:D010235 Paraganglioma arsenic trioxide 4.6919927285
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 5.1212520081
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 4.1418163543
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 3.9311118676 11399792 11896295 11222880
MESH:D011471 Prostatic Neoplasms arsenic trioxide 3.2019131511
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 4.4218990726
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 4.5416646077
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 2.2116192470
MESH:D013274 Stomach Neoplasms arsenic trioxide 1.8617007042
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 4.7712697716
MESH:D013964 Thyroid Neoplasms arsenic trioxide 3.4319014326
MESH:D016171 Torsades de Pointes arsenic trioxide 4.7015213294
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 2.6112845720 20435036 12973940 11780464
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 5.4612125929
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 5.1215886252
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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