AutismKB 2.0

Annotation Detail for WDR31


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Basic Information Top
Gene Symbol:WDR31 ( FLJ35921 )
Gene Full Name: WD repeat domain 31
Band: 9q32
Quick LinksEntrez ID:114987; OMIM: NA; Uniprot ID:WDR31_HUMAN; ENSEMBL ID: ENSG00000148225; HGNC ID: 21421
Relate to Another Database: SFARIGene; denovo-db
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Chemical ID Chemical Name Interaction Interaction Action Publication
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene affects the expression of WDR31 mRNAaffects expression 21346803
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of WDR31 mRNAaffects expression 17555576
D013629 Tamoxifen Tamoxifen affects the expression of WDR31 mRNAaffects expression 17555576
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 5.4114745880
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 4.8117505938
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 1.8914692618
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 4.1211256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 2.9115885639
MESH:D001943 Breast Neoplasms Tamoxifen 2.1619011961 19059307 17893378 18629630 20065188 11161223 20544844 19244106 15565566 18351453 19200415 19155303 17261762 18855134 21152245 16273361 19066611 20135344 18821012 16202921 18997820 19103187 19487384 19084267 15668708 20390343 19189212 19410462 17049068 18425577 19115204 19142967 21138602 20005174 18984771 20859285 16873071 17440819 17242785 19189210 16818667 19289846 19221464 18815881 19288272
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 5.1619066611
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 3.1416705839
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 3.1416924424
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 4.0617572228
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 3.066135515
MESH:D002779 Cholestasis Ethinyl Estradiol 3.2015861022 16919318 11677210 17333356 17681005 16105132 17110522
MESH:D003490 Cyanosis 2,6-dinitrotoluene 4.6718551238
MESH:D003711 Demyelinating Diseases Tamoxifen 5.0219031437
MESH:D003928 Diabetic Nephropathies Tamoxifen 3.8919279558
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 2.0621346803 18551238
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 10.9612538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 10.9619031437
MESH:D016889 Endometrial Neoplasms Tamoxifen 3.3120544844 16202921 17893378 19155303
MESH:D005234 Fatty Liver Ethinyl Estradiol 9.3415345470
MESH:D005234 Fatty Liver Tamoxifen 9.3419224547 14986274
MESH:D052776 Female Urogenital Diseases Tamoxifen 3.4716709447
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 5.2714745880
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 4.9219069698
MESH:D007021 Hypospadias Ethinyl Estradiol 4.4616945680 16569931
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.9912013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 2.7617937319
MESH:D007249 Inflammation Tamoxifen 2.5519457130
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 8.7016705839
MESH:D007680 Kidney Neoplasms Tamoxifen 8.7018625569
MESH:D008064 Lipidoses Tamoxifen 3.4615342952 17567588
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 1.7518564211
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 5.007678174
MESH:D008113 Liver Neoplasms Tamoxifen 5.0016684651
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 2.792876786 2876784 6135515
MESH:D008175 Lung Neoplasms Tamoxifen 1.7518625569
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 4.5019428831
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 2.8814580682 19196722 19196723 11731420 16827153
MESH:D020149 Manganese Poisoning Tamoxifen 5.4119453300
MESH:D008545 Melanoma Tamoxifen 1.9212393984 19393235
MESH:D018328 Melanoma, Amelanotic Tamoxifen 4.9215990972
MESH:D009336 Necrosis 2,6-dinitrotoluene 4.607678174 18551238
MESH:D009362 Neoplasm Metastasis Tamoxifen 2.6819393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.6219410462
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 4.8719196722 19200415 19189210
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 3.8816049721
MESH:D016584 Panic Disorder Ethinyl Estradiol 4.2211578682
MESH:D011471 Prostatic Neoplasms Tamoxifen 3.0815067354
MESH:D011537 Pruritus Ethinyl Estradiol 4.0516919318 15861022
MESH:D012640 Seizures 2,6-dinitrotoluene 2.8218551238
MESH:D013088 Spermatocele Ethinyl Estradiol 14.6716709447
MESH:D013088 Spermatocele Tamoxifen 14.6716709447
MESH:D013119 Spinal Cord Injuries Tamoxifen 4.7819457130
MESH:D019851 Thrombophilia Ethinyl Estradiol 4.1511994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.5715669648
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 5.5016049721
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 5.5017572228 16712894 8653321
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 5.0610091137
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.8814692618
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 4.0214671159 15869587
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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