AutismKB 2.0

Annotation Detail for VASN


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Basic Information Top
Gene Symbol:VASN ( SLITL2 )
Gene Full Name: vasorin
Band: 16p13.3
Quick LinksEntrez ID:114990; OMIM: 608843; Uniprot ID:VASN_HUMAN; ENSEMBL ID: ENSG00000168140; HGNC ID: 18517
Relate to Another Database: SFARIGene; denovo-db
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Chemical ID Chemical Name Interaction Interaction Action Publication
C115284 2-cyano-3-hydroxy-N-(4-(trifluoromethyl)phenyl)-2-hepten-6-ynamide 2-cyano-3-hydroxy-N-(4-(trifluoromethyl)phenyl)-2-hepten-6-ynamide results in decreased expression of VASN mRNAdecreases expression 17028423
D001564 Benzo(a)pyrene Benzo(a)pyrene results in increased expression of VASN mRNAincreases expression 20064835
D002251 Carbon Tetrachloride Carbon Tetrachloride affects the expression of VASN mRNAaffects expression 17484886
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of VASN mRNAincreases expression 17942748
C006253 pirinixic acid pirinixic acid results in decreased expression of VASN mRNAdecreases expression 18445702
D020123 Sirolimus Sirolimus results in decreased expression of VASN mRNAdecreases expression 17028423
D016559 Tacrolimus Tacrolimus results in decreased expression of VASN mRNAdecreases expression 17028423
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 4.3817505938
MESH:D055371 Acute Lung Injury pirinixic acid 3.4218653653
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 4.3720127859 20464547
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 4.3714692618
MESH:D000236 Adenoma Benzo(a)pyrene 2.806695378
MESH:D018248 Adenoma, Liver Cell pirinixic acid 3.8816434500
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 4.4319183758
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.8211256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 2.8215885639
MESH:D001321 Autistic Disorder Sirolimus 3.1921115397
MESH:D001778 Blood Coagulation Disorders pirinixic acid 3.4319483382
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 2.0017474063 20146248
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 4.1415721981 16124888 10355542 16011737 3786805 16097048 15673190 18705752 16227642 16050911 16192424 15700767
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 3.6118788625
MESH:D006528 Carcinoma, Hepatocellular Sirolimus 3.6119335982
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 5.2620419170
MESH:D002294 Carcinoma, Squamous Cell Sirolimus 5.2619435901
MESH:D002318 Cardiovascular Diseases Tacrolimus 4.7917703430
MESH:D002779 Cholestasis Ethinyl Estradiol 8.4215861022 17681005 17110522 16105132 17333356 11677210 16919318
MESH:D002779 Cholestasis pirinixic acid 8.4219176532
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.5318249437
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 2.1010092053 3732212 7179309 10915739 6884620 7440962 15027814 19336974 2869522 9327722 16227642 17522070 21278145 7120509 11566570 15998439 6623471 19085960 15968718 3786805 4309450 16177239
MESH:D004381 Duodenal Ulcer Tacrolimus 5.4717202747
MESH:D004487 Edema pirinixic acid 2.7612083418
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 3.5212538720
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 2.0616530937
MESH:D005234 Fatty Liver Carbon Tetrachloride 14.7412631006 15959796 61145 12795759 19224547 17595544 16045604 16239168
MESH:D005234 Fatty Liver Ethinyl Estradiol 14.7415345470
MESH:D005234 Fatty Liver pirinixic acid 14.7419236843 20131406
MESH:D005355 Fibrosis Carbon Tetrachloride 3.8118705752
MESH:D006083 Graft Occlusion, Vascular 2-cyano-3-hydroxy-N-(4-(trifluoromethyl)phenyl)-2-hepten-6-ynamide 8.2417028423
MESH:D006086 Graft vs Host Disease Tacrolimus 6.2416376943
MESH:D006130 Growth Disorders Tacrolimus 5.0811041285
MESH:D006258 Head and Neck Neoplasms Sirolimus 4.6419435901
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 2.7820471113
MESH:D006333 Heart Failure pirinixic acid 2.6920558911
MESH:D006505 Hepatitis Carbon Tetrachloride 3.9219110552 19900420
MESH:D006529 Hepatomegaly pirinixic acid 3.3518467677 16221962 19176532 19772884
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 4.9316899240
MESH:D006943 Hyperglycemia pirinixic acid 3.4520558911
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 4.4515338365
MESH:D006984 Hypertrophy Sirolimus 5.5119211884
MESH:C537153 Hypomagnesemia primary Tacrolimus 6.5511041285
MESH:D007021 Hypospadias Ethinyl Estradiol 4.1716945680 16569931
MESH:D007022 Hypotension Tacrolimus 5.4211041285
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.7712013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 2.6617937319
MESH:D007333 Insulin Resistance pirinixic acid 2.8016306350
MESH:D007674 Kidney Diseases Tacrolimus 4.4111041285
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 2.9416221502 17157831 17334410 17174718 16239168 11408273 16943688 21278145 11903743
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 3.7817922224 17557913 15650968 18412020 17565644 18420326 12445418 16027843 12649538 15673190 15925388 18705752 18054572 15057751 12389079 16011737 12666154 18376398 15370692 18210741 16116963 11481614 15931870 12445421 16015684 17640975 14512876 15818738 16638106 15876570 18472094 18481824 14620537 18418968 18006644 16136751 18277467 17631135 15052691 18187930 17698563 17976157 15893842 12741479 17823541 17525996 18317297 15730626 17481882 12667390 14716496 17944888 18429990 15362042 12958196 18156304 17869086 15338365 14748882 17708605 15996030 18339082 18472332 15123356 17805973 18263696 17714472 12632512 14724832 16192424 10355542 16248980 15959796 17721639 18279442 16033810 17900296 18166357 17761835 18395914 18251166 16097048 14716833 12898905 18395095 12609069 12632514 12586293 13678700 12546737 18205269 20821823 17766677
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 3.7815474484
MESH:D008106 Liver Cirrhosis, Experimental Sirolimus 3.7817050028
MESH:D008107 Liver Diseases Carbon Tetrachloride 2.1316246199 15720792 17285989 16964402 15830285
MESH:D017093 Liver Failure Carbon Tetrachloride 4.5215123358
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 3.9516899240 14706259
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 7.9021137059 20195826
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 7.9019294768
MESH:D008113 Liver Neoplasms pirinixic acid 7.9020007298 15890375 16377806
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 2.7715583823 12014681
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 1.5718520028 20464547 17053015 20869020 18569708 18816296 20135361 20064080 6695378
MESH:D008545 Melanoma Sirolimus 3.2519282848
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 9.6416381670
MESH:D009062 Mouth Neoplasms Sirolimus 9.6419435901
MESH:D009135 Muscular Diseases pirinixic acid 3.8616239165
MESH:D009203 Myocardial Infarction pirinixic acid 2.2419151258
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 3.1616411023
MESH:D009369 Neoplasms Benzo(a)pyrene 5.2211141357
MESH:D009369 Neoplasms pirinixic acid 5.2217405874
MESH:D019636 Neurodegenerative Diseases Tacrolimus 5.1815081597
MESH:D009765 Obesity pirinixic acid 1.8620558911
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.9911578682
MESH:D010300 Parkinson Disease Sirolimus 3.8219682553
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 2.9317292933
MESH:D011537 Pruritus Ethinyl Estradiol 3.7116919318 15861022
MESH:D015427 Reperfusion Injury pirinixic acid 2.5019058328
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 2.4819755658 10029692
MESH:D013088 Spermatocele Ethinyl Estradiol 4.3816709447
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 1.562093021 20155912
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.9211994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.4015669648
MESH:D014402 Tuberous Sclerosis Sirolimus 5.9018495876 21115397
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 2.2617053015
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.6314692618
MESH:D014605 Uveitis Sirolimus 6.071336536
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.8214671159 15869587
No data
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AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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