AutismKB 2.0

Annotation Detail for LRRC42


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Basic Information Top
Gene Symbol:LRRC42 ( MGC8974,dJ167A19.4 )
Gene Full Name: leucine rich repeat containing 42
Band: 1p32.3
Quick LinksEntrez ID:115353; OMIM: NA; Uniprot ID:LRC42_HUMAN; ENSEMBL ID: ENSG00000116212; HGNC ID: 28792
Relate to Another Database: SFARIGene; denovo-db
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Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of LRRC42 mRNAaffects expression 21346803
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene affects the expression of LRRC42 mRNAaffects expression 21346803
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 3.1316705839
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 3.1316705839
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 3.096135515
MESH:D003490 Cyanosis 2,4-dinitrotoluene 13.5818551238
MESH:D003490 Cyanosis 2,6-dinitrotoluene 13.5818551238
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 4.2221346803 18551238
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 4.2221346803 18551238
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 8.8416705839
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 8.8416705839
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 2.297678174
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 2.822876784 6135515 2876786
MESH:D009336 Necrosis 2,4-dinitrotoluene 13.5318551238
MESH:D009336 Necrosis 2,6-dinitrotoluene 13.5318551238 7678174
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 10.6112819281 16049721
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 10.6116049721
MESH:D012640 Seizures 2,4-dinitrotoluene 6.9518551238
MESH:D012640 Seizures 2,6-dinitrotoluene 6.9518551238
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 5.5216049721
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 5.5216049721
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 15.1710091137
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 15.1710091137
No data
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Syndromic Genes

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AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018