AutismKB 2.0

Annotation Detail for KIR3DL3


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Basic Information Top
Gene Symbol:KIR3DL3 ( CD158Z,KIR3DL7,KIR44,KIRC1 )
Gene Full Name: killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 3
Band: 19q13.42
Quick LinksEntrez ID:115653; OMIM: 610095; Uniprot ID:KI3L3_HUMAN; ENSEMBL ID: ENSG00000189013; HGNC ID: 16312
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa04612Antigen processing and presentation
No data
No data
No data
No data
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D001151 Arsenic Arsenic affects the expression of KIR3DL3 mRNAaffects expression 18414638
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D018246 Adrenocortical Adenoma Arsenic 6.6317306315
MESH:D020261 Arsenic Poisoning Arsenic 2.9716251483 12569548 18414634 16835338
MESH:D050197 Atherosclerosis Arsenic 3.5319371607 12928151
MESH:D002280 Carcinoma, Basal Cell Arsenic 3.8517687452 15504454
MESH:D006528 Carcinoma, Hepatocellular Arsenic 2.3316507464 17306315
MESH:D002294 Carcinoma, Squamous Cell Arsenic 2.8018922899 15504454 17687452
MESH:D002295 Carcinoma, Transitional Cell Arsenic 4.6518640142
MESH:D002318 Cardiovascular Diseases Arsenic 3.8115738583 17938729 19152805
MESH:D002340 Carotid Artery Diseases Arsenic 4.8418022660 16973168
MESH:D005534 Foot Diseases Arsenic 6.986392382
MESH:D017488 Hyperkeratosis, Epidermolytic Arsenic 5.0317050553
MESH:D006973 Hypertension Arsenic 3.0216076760 11953799 9931084
MESH:D006987 Hypesthesia Arsenic 6.9816093927
MESH:D007642 Keratosis Arsenic 6.0816930632 12749816
MESH:D015473 Leukemia, Promyelocytic, Acute Arsenic 3.8817339181
MESH:D008107 Liver Diseases Arsenic 2.6311134558
MESH:D008113 Liver Neoplasms Arsenic 2.8316368122
MESH:D008175 Lung Neoplasms Arsenic 2.2119168569 17306315 17976673
MESH:D017202 Myocardial Ischemia Arsenic 4.4415371236
MESH:D009436 Neural Tube Defects Arsenic 3.7816620997
MESH:D020078 Neurogenic Inflammation Arsenic 5.0717056641
MESH:D010051 Ovarian Neoplasms Arsenic 2.8617306315
MESH:D010523 Peripheral Nervous System Diseases Arsenic 4.9616093927
MESH:D016491 Peripheral Vascular Diseases Arsenic 6.0815371236 6392382 16905509
MESH:D011471 Prostatic Neoplasms Arsenic 3.5316140617
MESH:D011507 Proteinuria Arsenic 4.7021343184
MESH:D012871 Skin Diseases Arsenic 2.8417050553 15952646 16353154 19834688 17453740 17548696 16702368 16759981 18709164 6392382 17938729
MESH:D012878 Skin Neoplasms Arsenic 3.2117029826 16251483 17976673 17050553 19538983 15504454
MESH:D001749 Urinary Bladder Neoplasms Arsenic 2.9717306315 11144890 18640142 17976673 15987713 19322015 19429237
MESH:D014652 Vascular Diseases Arsenic 5.8217056641
Pathway ID Pathway Name
KEGG:04612 Antigen processing and presentation
KEGG:04650 Natural killer cell mediated cytotoxicity
Pharmacogenomics Knowledge Base Top
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018