AutismKB 2.0

Annotation Detail for ZMYND19


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Basic Information Top
Gene Symbol:ZMYND19 ( MIZIP,RP11-48C7.4 )
Gene Full Name: zinc finger, MYND-type containing 19
Band: 9q34.3
Quick LinksEntrez ID:116225; OMIM: 611424; Uniprot ID:ZMY19_HUMAN; ENSEMBL ID: ENSG00000165724; HGNC ID: 21146
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of ZMYND19 mRNAaffects expression 21346803
D000082 Acetaminophen Acetaminophen affects the expression of ZMYND19 mRNAaffects expression 17562736
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of ZMYND19 mRNAdecreases expression 19150397
20382639
C006253 pirinixic acid pirinixic acid results in increased expression of ZMYND19 mRNAincreases expression 18301758
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin binds to AHR protein] which results in decreased expression of ZMYND19 mRNAaffects binding|decreases expression 16214954
D014212 Tretinoin Tretinoin results in increased expression of ZMYND19 mRNAincreases expression 17218384
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 3.3115322242 14514962 11752688
MESH:D055371 Acute Lung Injury pirinixic acid 3.4718653653
MESH:D018248 Adenoma, Liver Cell pirinixic acid 11.4916434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 11.4916835633
MESH:D000505 Alopecia Tretinoin 3.8715955085
MESH:D000740 Anemia Tetrachlorodibenzodioxin 3.2511748828
MESH:D000799 Angioedema Acetaminophen 4.3610982225
MESH:D001169 Arthritis, Experimental Tretinoin 3.2516412693
MESH:D001172 Arthritis, Rheumatoid Tretinoin 2.3216292516
MESH:D001249 Asthma Tretinoin 2.4216456186
MESH:D001321 Autistic Disorder Acetaminophen 1.4018445737
MESH:D001471 Barrett Esophagus Tretinoin 4.7816935849
MESH:D001778 Blood Coagulation Disorders pirinixic acid 17.2519483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 17.2512125929
MESH:D001778 Blood Coagulation Disorders Tretinoin 17.2516206674 16197459
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 4.3115340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.9515746008
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 1.9520435547
MESH:D001943 Breast Neoplasms Tretinoin 1.9516443354 16166294 16873071
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 5.0516813970
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 3.0516835633
MESH:D018236 Carcinoma, Embryonal Tretinoin 5.6816168501
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 4.7516705839
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 4.753084413
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 4.751917145
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 2.3616051514 16096774
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.5218850075 16120746 18670907
MESH:D002386 Cataract Acetaminophen 7.7810977129
MESH:D002386 Cataract Tretinoin 7.7817460283
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 2.9320889678
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 5.0516129372
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 3.4516835633
MESH:D002779 Cholestasis pirinixic acid 3.0519176532
MESH:D002822 Choriocarcinoma Tretinoin 5.6816461808
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 6.1315668235 8697196 12621046 16354765 15340226
MESH:D002972 Cleft Palate Tretinoin 6.139407595
MESH:D003092 Colitis Tretinoin 4.1217035595
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 3.3417141729 14669216
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 2.5215322242 20055451 10048152
MESH:D019465 Craniofacial Abnormalities Tretinoin 2.529224671 14991402 9211117 17551590 9125849 9664655 9142499 10589399 16925845 8800419
MESH:D003490 Cyanosis 2,4-dinitrotoluene 4.4318551238
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.5518249437
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 1.7217107852
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 6.5721346803 18551238
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 6.5719923254 11529661 19739265 10663392 19085960 11743745 16177239 17906064 14986274 12153990 10774834 18071297 11421492 11739529 12594235 12540782 12392966 11287661 19164858 12705907 16109766 10915739 16393943 14550746 12958197 18713872 17562736 14725611 19420014 19416960 2444490 17522070 15968718 11461765 19370779 16781746 16485898 11834606 16227642 16081117 15619225
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 6.5720420201
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.6219426721
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.9911462148
MESH:D004487 Edema pirinixic acid 7.6312083418
MESH:D004487 Edema Tetrachlorodibenzodioxin 7.6311000095 12711302
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 13.7415322242 16714409 18230668
MESH:D004489 Edema, Cardiac Tretinoin 13.7418230668
MESH:D016889 Endometrial Neoplasms Tretinoin 3.3016569247
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 3.339294722 10568697
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 2.1320426865
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 9.6111564622
MESH:D005124 Eye Abnormalities Tretinoin 9.6116938888 9664655
MESH:D005234 Fatty Liver pirinixic acid 3.0920131406 19236843
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.8711858732
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 10.0420067830
MESH:D005355 Fibrosis Tretinoin 10.0417994277
MESH:D005756 Gastritis Acetaminophen 4.1916983495
MESH:D005909 Glioblastoma Tretinoin 3.1917312396
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 5.1210696789
MESH:D006258 Head and Neck Neoplasms Tretinoin 3.3816096774
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 5.6816084493
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 7.0211294989 10048152
MESH:D006330 Heart Defects, Congenital Tretinoin 7.029664655 14991402
MESH:D006333 Heart Failure pirinixic acid 2.7120558911
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.6611000095
MESH:D006529 Hepatomegaly pirinixic acid 9.6916221962 18467677 19772884 19176532
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 9.6915340226 16120746 12621046
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 4.5716959395 15340226 8697196 18606429 16354765
MESH:D006930 Hyperalgesia Acetaminophen 8.4816870215
MESH:D006930 Hyperalgesia Tretinoin 8.4816870215
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 4.9916778211
MESH:D006943 Hyperglycemia pirinixic acid 3.4920558911
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 2.0018670907 18850075
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 1.9912200463 12878042
MESH:D007333 Insulin Resistance pirinixic acid 2.8216306350
MESH:D007410 Intestinal Diseases Tretinoin 4.1817994277
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 11.0416580747
MESH:D007569 Jaw Abnormalities Tretinoin 11.0415992940 17551590
MESH:D007674 Kidney Diseases Acetaminophen 2.3615629191 12587719
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 3.2416705839
MESH:D007938 Leukemia Tretinoin 2.9017143497
MESH:D007951 Leukemia, Myeloid Tretinoin 4.0216482212 19285840 16932348
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 2.1217596541 19850784 16294345
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 3.3419035177 19029980 17368321 17301526 19075265 16788101 17217047 12679006 16331271 16823087 9834237 19225113 17361223 17294898 17107899 16935935 17712046 17506722 17339181 16891316 16766008 16140955 19642359 15748426 17649720
MESH:D017880 Limb Deformities, Congenital Tretinoin 3.539224671
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 3.5515474484
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 3.5512878042
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 3.5518397230 16248980
MESH:D008107 Liver Diseases Acetaminophen 1.6911587558 12587719 16610002 16611625 19784758 19014921 12969438 19460945
MESH:D017114 Liver Failure, Acute Acetaminophen 3.5416871587 17185352
MESH:D008113 Liver Neoplasms pirinixic acid 4.5815890375 16377806 20007298
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 4.5816984957
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 2.2812151625
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 1.2411884234 19555203
MESH:D008527 Medulloblastoma Tretinoin 2.8817453147
MESH:D008545 Melanoma Tretinoin 1.9716752155
MESH:D008546 Melanoma, Experimental Acetaminophen 3.9819513568
MESH:D008591 Meningomyelocele Tretinoin 4.8416940565
MESH:D009135 Muscular Diseases pirinixic acid 3.9216239165
MESH:D009190 Myelodysplastic Syndromes Tretinoin 3.2417596541
MESH:D009203 Myocardial Infarction pirinixic acid 2.2519151258
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 3.2712213967
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 3.1916411023
MESH:D009336 Necrosis 2,4-dinitrotoluene 4.3218551238
MESH:D009369 Neoplasms pirinixic acid 5.3617405874
MESH:D009369 Neoplasms Tretinoin 5.3616594593 16946489
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 10.8114600291
MESH:D009421 Nervous System Malformations Tretinoin 10.819125849
MESH:D009436 Neural Tube Defects Tretinoin 3.249142499
MESH:D019636 Neurodegenerative Diseases Acetaminophen 3.1418514411
MESH:D009765 Obesity pirinixic acid 1.8720558911
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 3.7312819281 16049721
MESH:D010051 Ovarian Neoplasms Tretinoin 2.4216936753
MESH:D010146 Pain Acetaminophen 7.4916870215
MESH:D010146 Pain Tretinoin 7.4916870215
MESH:D010190 Pancreatic Neoplasms Tretinoin 2.5515976015
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.7712520081
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.9418163543
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 3.6511118676 11222880 11896295 11399792
MESH:D011507 Proteinuria Tretinoin 3.9516636307
MESH:D011625 Pterygium Tretinoin 5.2616723453
MESH:D015427 Reperfusion Injury pirinixic acid 2.5219058328
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 4.2218990726
MESH:D012208 Rhabdomyosarcoma Tretinoin 4.4516283617 16116481
MESH:D012640 Seizures 2,4-dinitrotoluene 2.7318551238
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 5.9916192470
MESH:D012878 Skin Neoplasms Tretinoin 5.9916467112
MESH:D013274 Stomach Neoplasms Tretinoin 1.8017261132
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 4.4212697716
MESH:D013964 Thyroid Neoplasms Tretinoin 3.2617045167 16026305
MESH:D014062 Tongue Neoplasms Tretinoin 4.0916051514
MESH:D014376 Tuberculosis Tretinoin 3.4116040207
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 2.3816049721
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 4.7810091137
MESH:D014581 Urticaria Acetaminophen 3.3310982225
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 3.9816129372
MESH:D014604 Uveal Neoplasms Tretinoin 5.1316752155
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 5.1212125929
MESH:D014820 Vitiligo Tretinoin 4.4416761959
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.7715886252
MESH:D009396 Wilms Tumor Tretinoin 4.2516287080
No data
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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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