AutismKB 2.0

Annotation Detail for ABHD15


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Basic Information Top
Gene Symbol:ABHD15 ( - )
Gene Full Name: abhydrolase domain containing 15
Band: 17q11.2
Quick LinksEntrez ID:116236; OMIM: NA; Uniprot ID:ABH15_HUMAN; ENSEMBL ID: ENSG00000168792; HGNC ID: 26971
Relate to Another Database: SFARIGene; denovo-db
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Chemical ID Chemical Name Interaction Interaction Action Publication
C006253 pirinixic acid [pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of ABHD15 mRNAaffects binding|increases activity|increases expression 19710929
C059514 resveratrol resveratrol results in increased expression of ABHD15 mRNAincreases expression 19371625
D014635 Valproic Acid Valproic Acid results in increased expression of ABHD15 mRNAincreases expression 19101580
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Valproic Acid 4.238875741
MESH:D000015 Abnormalities, Multiple Valproic Acid 4.4119490988
MESH:D058186 Acute Kidney Injury resveratrol 4.3316538975
MESH:D055371 Acute Lung Injury pirinixic acid 3.6418653653
MESH:D000236 Adenoma resveratrol 3.5415688382
MESH:D018248 Adenoma, Liver Cell pirinixic acid 4.2216434500
MESH:D000544 Alzheimer Disease resveratrol 2.6416183991 16162502
MESH:D000550 Amblyopia Valproic Acid 6.1017688650
MESH:D001008 Anxiety Disorders Valproic Acid 3.9417497229
MESH:D001169 Arthritis, Experimental resveratrol 3.7517115116
MESH:D050197 Atherosclerosis resveratrol 3.5116873680 17967414
MESH:D001321 Autistic Disorder Valproic Acid 1.9818396377 18940202 17157402 19232924 17688650 18775368 17507914 16609825 18985861 15238991 18316065 19460635 18558336 18177632 20603192
MESH:D001714 Bipolar Disorder Valproic Acid 3.2617594078 20046352
MESH:D001778 Blood Coagulation Disorders pirinixic acid 3.6319483382
MESH:D001848 Bone Diseases, Developmental Valproic Acid 3.668888407
MESH:D002545 Brain Ischemia resveratrol 5.0217600658
MESH:D001943 Breast Neoplasms resveratrol 2.6516393696 17651959 17534123
MESH:D006528 Carcinoma, Hepatocellular resveratrol 2.3416227395 19321006
MESH:D018827 Carcinoma, Lewis Lung resveratrol 5.3316675471
MESH:D002294 Carcinoma, Squamous Cell resveratrol 2.8116227395
MESH:D002318 Cardiovascular Diseases resveratrol 3.7615458977
MESH:D002659 Child Development Disorders, Pervasive Valproic Acid 2.8320734317
MESH:D002779 Cholestasis pirinixic acid 3.1519176532
MESH:D003092 Colitis resveratrol 4.7816474422
MESH:D003110 Colonic Neoplasms resveratrol 2.5116338953
MESH:D015179 Colorectal Neoplasms resveratrol 2.2316550006
MESH:D003327 Coronary Disease resveratrol 4.0116507316
MESH:D019465 Craniofacial Abnormalities Valproic Acid 1.9116575769 8888407 17688650
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.5918249437
MESH:D003921 Diabetes Mellitus, Experimental resveratrol 4.1616873680
MESH:D003928 Diabetic Nephropathies resveratrol 4.3816286809
MESH:D056486 Drug-Induced Liver Injury Valproic Acid 2.2619641884 1733752
MESH:D004421 Dystonia Valproic Acid 4.581851702
MESH:D004487 Edema pirinixic acid 8.5412083418
MESH:D004487 Edema resveratrol 8.548985016
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental resveratrol 4.6117872969
MESH:D020345 Enterocolitis, Necrotizing resveratrol 5.5017923197
MESH:D004831 Epilepsies, Myoclonic Valproic Acid 4.8117275665 3659116
MESH:D004828 Epilepsies, Partial Valproic Acid 4.7816628512 3922381
MESH:D004827 Epilepsy Valproic Acid 3.1220417680 18234410
MESH:D004832 Epilepsy, Absence Valproic Acid 4.007562514 6426943 6254150
MESH:D017029 Epilepsy, Complex Partial Valproic Acid 4.957750514
MESH:D004830 Epilepsy, Tonic-Clonic Valproic Acid 4.813659116
MESH:D005234 Fatty Liver pirinixic acid 9.3720131406 19236843
MESH:D005234 Fatty Liver Valproic Acid 9.3714986274 19224547
MESH:D005315 Fetal Diseases Valproic Acid 5.7516575769
MESH:D005317 Fetal Growth Retardation Valproic Acid 4.718888407 18558336
MESH:D006333 Heart Failure pirinixic acid 2.7820558911
MESH:D006529 Hepatomegaly pirinixic acid 3.6418467677 16221962 19772884 19176532
MESH:D006561 Herpes Simplex resveratrol 4.9216876885
MESH:D006849 Hydrocephalus Valproic Acid 5.6117688650
MESH:D006937 Hypercholesterolemia resveratrol 4.4917188708
MESH:D006943 Hyperglycemia pirinixic acid 3.6320558911
MESH:D006949 Hyperlipidemias resveratrol 4.5616873680
MESH:D017379 Hypertrophy, Left Ventricular resveratrol 4.7517488730
MESH:D020244 Infarction, Middle Cerebral Artery resveratrol 5.3017600658
MESH:D007249 Inflammation resveratrol 3.0316366677
MESH:D007251 Influenza, Human resveratrol 5.4116624496
MESH:D007333 Insulin Resistance pirinixic acid 2.9016306350
MESH:D015470 Leukemia, Myeloid, Acute Valproic Acid 2.2016294345 17596541
MESH:D015473 Leukemia, Promyelocytic, Acute resveratrol 3.8416087638
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 1.3515474484
MESH:D008113 Liver Neoplasms pirinixic acid 5.0615890375 20007298 16377806
MESH:D008113 Liver Neoplasms resveratrol 5.0619321006 19073162 20405173 19812893
MESH:D017563 Lung Diseases, Interstitial Valproic Acid 5.1317228818
MESH:D016393 Lymphoma, B-Cell resveratrol 4.8317088997
MESH:D008228 Lymphoma, Non-Hodgkin resveratrol 4.2614749477
MESH:D015674 Mammary Neoplasms, Animal resveratrol 4.9915688416
MESH:D008325 Mammary Neoplasms, Experimental resveratrol 3.378985016 11606380
MESH:D008545 Melanoma resveratrol 2.4117992120
MESH:D008659 Metabolic Diseases resveratrol 4.8617112576
MESH:D008881 Migraine Disorders Valproic Acid 3.5018803445 18765137
MESH:D009101 Multiple Myeloma resveratrol 3.7716490592 17164350 17049120 16267019 17935668 14749477
MESH:D009134 Muscular Atrophy, Spinal resveratrol 5.6117962980
MESH:D009135 Muscular Diseases pirinixic acid 4.1616239165
MESH:D009139 Musculoskeletal Abnormalities Valproic Acid 4.518888407
MESH:D009190 Myelodysplastic Syndromes Valproic Acid 3.3717596541
MESH:D009203 Myocardial Infarction pirinixic acid 6.2419151258
MESH:D009203 Myocardial Infarction resveratrol 6.2417125593 16317513 17188708 17015251 16525036 16456233
MESH:D017202 Myocardial Ischemia resveratrol 4.3717125593 17015251
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 3.2916411023
MESH:D009205 Myocarditis resveratrol 5.5017322642
MESH:D009369 Neoplasms pirinixic acid 2.1217405874
MESH:D009374 Neoplasms, Experimental resveratrol 4.658985016
MESH:D009436 Neural Tube Defects Valproic Acid 3.3916359493 8888407
MESH:D019636 Neurodegenerative Diseases resveratrol 4.1917652729
MESH:D020078 Neurogenic Inflammation resveratrol 4.9317929310
MESH:D009765 Obesity pirinixic acid 1.8920558911
MESH:D015663 Osteoporosis, Postmenopausal resveratrol 4.7817513867
MESH:D011297 Prenatal Exposure Delayed Effects resveratrol 12.4416679765
MESH:D011297 Prenatal Exposure Delayed Effects Valproic Acid 12.4420603192
MESH:D011471 Prostatic Neoplasms resveratrol 3.5717675339 17804756 17718901 17636462 15767336 16731767
MESH:D019310 Pseudolymphoma Valproic Acid 5.4111422049 12752131
MESH:D051436 Renal Insufficiency, Chronic resveratrol 6.4516325855
MESH:D015427 Reperfusion Injury pirinixic acid 7.1819058328
MESH:D015427 Reperfusion Injury resveratrol 7.1817058453 16314181 16317513 17520802 15827377
MESH:D012208 Rhabdomyosarcoma Valproic Acid 4.7019155313
MESH:D012559 Schizophrenia Valproic Acid 2.1119110320 15737665
MESH:D012640 Seizures Valproic Acid 3.0211738929 17978042 15475178 14763951 1511512 16876388 11044598 3137016
MESH:D012878 Skin Neoplasms resveratrol 3.208985016 15837718
MESH:D016135 Spinal Dysraphism Valproic Acid 4.1319490988
MESH:D013226 Status Epilepticus Valproic Acid 5.4112833885
OMIM:601367 STROKE, ISCHEMIC resveratrol 4.9316321402
MESH:D014062 Tongue Neoplasms resveratrol 4.6616227395
MESH:D014178 Translocation, Genetic Valproic Acid 6.1017262798
MESH:D020194 Unverricht-Lundborg Syndrome Valproic Acid 5.263119515
MESH:D014564 Urogenital Abnormalities Valproic Acid 5.308888407
MESH:D002583 Uterine Cervical Neoplasms resveratrol 4.5517473185
MESH:D014594 Uterine Neoplasms resveratrol 4.7217044934
MESH:D018487 Ventricular Dysfunction, Left resveratrol 4.9517488730
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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