AutismKB 2.0

Annotation Detail for ACAP3


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Basic Information Top
Gene Symbol:ACAP3 ( CENTB5,KIAA1716 )
Gene Full Name: ArfGAP with coiled-coil, ankyrin repeat and PH domains 3
Band: 1p36.33
Quick LinksEntrez ID:116983; OMIM: NA; Uniprot ID:ACAP3_HUMAN; ENSEMBL ID: ENSG00000131584; HGNC ID: 16754
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000082 Acetaminophen Acetaminophen affects the expression of ACAP3 mRNAaffects expression 17562736
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000799 Angioedema Acetaminophen 5.2610982225
MESH:D001321 Autistic Disorder Acetaminophen 1.3918445737
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 1.413084413
MESH:D002386 Cataract Acetaminophen 2.8610977129
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 1.6919370779 10915739 15968718 11743745 17562736 11287661 12594235 19739265 10774834 18713872 19420014 12153990 19164858 11529661 16485898 15619225 16393943 14550746 12392966 12540782 19416960 19923254 11421492 2444490 16781746 10663392 14725611 17906064 17522070 11739529 19085960 12705907 12958197 14986274 16081117 16227642 11834606 16177239 16109766 18071297 11461765
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 5.5119426721
MESH:D005756 Gastritis Acetaminophen 5.0916983495
MESH:D006930 Hyperalgesia Acetaminophen 3.1516870215
MESH:D007674 Kidney Diseases Acetaminophen 2.4715629191 12587719
MESH:D008107 Liver Diseases Acetaminophen 1.7219460945 12587719 12969438 16610002 19014921 11587558 19784758 16611625
MESH:D017114 Liver Failure, Acute Acetaminophen 3.8117185352 16871587
MESH:D008546 Melanoma, Experimental Acetaminophen 4.4719513568
MESH:D019636 Neurodegenerative Diseases Acetaminophen 3.3618514411
MESH:D010146 Pain Acetaminophen 2.8716870215
MESH:D014581 Urticaria Acetaminophen 3.6710982225
Pathway ID Pathway Name
KEGG:04144 Endocytosis
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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018