Annotation Detail for SH2D1B
Basic Information Top
| Gene Symbol: | SH2D1B ( EAT2 ) |
|---|---|
| Gene Full Name: | SH2 domain containing 1B |
| Band: | 1q23.3 |
| Quick Links | Entrez ID:117157; OMIM: 608510; Uniprot ID:SH21B_HUMAN; ENSEMBL ID: ENSG00000198574; HGNC ID: 30416 |
| Relate to Another Database: | SFARIGene; denovo-db |
| No data |
| Pathway ID | Pathway Name |
|---|---|
| hsa04650 | Natural killer cell mediated cytotoxicity |
| No data |
| No data |
| No data |
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Related Diseases/Disorders| Chemical ID | Chemical Name | Interaction | Interaction Action | Publication |
|---|---|---|---|---|
| D001151 | Arsenic | Arsenic affects the expression of SH2D1B mRNA | affects expression | 18414638 |
| Disease ID | Disease Name | Direct Evidence | Inference Chemical Name | Inference Score | Publication |
|---|---|---|---|---|---|
| MESH:D018246 | Adrenocortical Adenoma | Arsenic | 6.63 | 17306315 | |
| MESH:D020261 | Arsenic Poisoning | Arsenic | 2.97 | 18414634 16835338 12569548 16251483 | |
| MESH:D050197 | Atherosclerosis | Arsenic | 3.53 | 12928151 19371607 | |
| MESH:D002280 | Carcinoma, Basal Cell | Arsenic | 3.85 | 15504454 17687452 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Arsenic | 2.33 | 16507464 17306315 | |
| MESH:D002294 | Carcinoma, Squamous Cell | Arsenic | 2.80 | 18922899 17687452 15504454 | |
| MESH:D002295 | Carcinoma, Transitional Cell | Arsenic | 4.65 | 18640142 | |
| MESH:D002318 | Cardiovascular Diseases | Arsenic | 3.81 | 15738583 17938729 19152805 | |
| MESH:D002340 | Carotid Artery Diseases | Arsenic | 4.84 | 18022660 16973168 | |
| MESH:D005534 | Foot Diseases | Arsenic | 6.98 | 6392382 | |
| MESH:D017488 | Hyperkeratosis, Epidermolytic | Arsenic | 5.03 | 17050553 | |
| MESH:D006973 | Hypertension | Arsenic | 3.02 | 16076760 11953799 9931084 | |
| MESH:D006987 | Hypesthesia | Arsenic | 6.98 | 16093927 | |
| MESH:D007642 | Keratosis | Arsenic | 6.08 | 16930632 12749816 | |
| MESH:D015473 | Leukemia, Promyelocytic, Acute | Arsenic | 3.88 | 17339181 | |
| MESH:D008107 | Liver Diseases | Arsenic | 2.63 | 11134558 | |
| MESH:D008113 | Liver Neoplasms | Arsenic | 2.83 | 16368122 | |
| MESH:D008175 | Lung Neoplasms | Arsenic | 2.21 | 19168569 17976673 17306315 | |
| MESH:D017202 | Myocardial Ischemia | Arsenic | 4.44 | 15371236 | |
| MESH:D009436 | Neural Tube Defects | Arsenic | 3.78 | 16620997 | |
| MESH:D020078 | Neurogenic Inflammation | Arsenic | 5.07 | 17056641 | |
| MESH:D010051 | Ovarian Neoplasms | Arsenic | 2.86 | 17306315 | |
| MESH:D010523 | Peripheral Nervous System Diseases | Arsenic | 4.96 | 16093927 | |
| MESH:D016491 | Peripheral Vascular Diseases | Arsenic | 6.08 | 6392382 16905509 15371236 | |
| MESH:D011471 | Prostatic Neoplasms | Arsenic | 3.53 | 16140617 | |
| MESH:D011507 | Proteinuria | Arsenic | 4.70 | 21343184 | |
| MESH:D012871 | Skin Diseases | Arsenic | 2.84 | 17050553 15952646 17548696 16702368 17938729 17453740 19834688 16353154 18709164 6392382 16759981 | |
| MESH:D012878 | Skin Neoplasms | Arsenic | 3.21 | 17976673 16251483 17029826 17050553 19538983 15504454 | |
| MESH:D001749 | Urinary Bladder Neoplasms | Arsenic | 2.97 | 19322015 17306315 15987713 18640142 17976673 19429237 11144890 | |
| MESH:D014652 | Vascular Diseases | Arsenic | 5.82 | 17056641 |
| Pathway ID | Pathway Name |
|---|---|
| KEGG:04650 | Natural killer cell mediated cytotoxicity |