Annotation Detail for HRASLS5
Basic Information Top
| Gene Symbol: | HRASLS5 ( HRLP5,RLP1,iNAT ) |
|---|---|
| Gene Full Name: | HRAS-like suppressor family, member 5 |
| Band: | 11q12.3 |
| Quick Links | Entrez ID:117245; OMIM: 611474; Uniprot ID:HRSL5_HUMAN; ENSEMBL ID: ENSG00000168004; HGNC ID: 24978 |
| Relate to Another Database: | SFARIGene; denovo-db |
Related Pathway Information| Chemical ID | Chemical Name | Interaction | Interaction Action | Publication |
|---|---|---|---|---|
| D000082 | Acetaminophen | Acetaminophen affects the expression of HRASLS5 mRNA | affects expression | 17562736 |
| D001556 | Lindane | Lindane results in decreased expression of HRASLS5 mRNA | decreases expression | 17785943 |
| C006253 | pirinixic acid | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of HRASLS5 mRNA | affects binding|decreases expression|increases activity | 19710929 |
| Disease ID | Disease Name | Direct Evidence | Inference Chemical Name | Inference Score | Publication |
|---|---|---|---|---|---|
| MESH:D055371 | Acute Lung Injury | pirinixic acid | 3.64 | 18653653 | |
| MESH:D018248 | Adenoma, Liver Cell | pirinixic acid | 4.22 | 16434500 | |
| MESH:D000382 | Agricultural Workers' Diseases | Lindane | 5.11 | 12661182 | |
| MESH:D000799 | Angioedema | Acetaminophen | 4.71 | 10982225 | |
| MESH:D001321 | Autistic Disorder | Acetaminophen | 1.39 | 18445737 | |
| MESH:D001778 | Blood Coagulation Disorders | pirinixic acid | 3.63 | 19483382 | |
| MESH:D001943 | Breast Neoplasms | Lindane | 3.18 | 14688026 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Acetaminophen | 1.41 | 3084413 | |
| MESH:D002386 | Cataract | Acetaminophen | 2.81 | 10977129 | |
| MESH:D002779 | Cholestasis | pirinixic acid | 3.15 | 19176532 | |
| MESH:D003876 | Dermatitis, Atopic | pirinixic acid | 2.59 | 18249437 | |
| MESH:D056486 | Drug-Induced Liver Injury | Acetaminophen | 1.68 | 12594235 12958197 19420014 16081117 17562736 19416960 11529661 14986274 19164858 11834606 12540782 12705907 18713872 14550746 11739529 14725611 19370779 16227642 11743745 11287661 19923254 17522070 2444490 19085960 16485898 16109766 12153990 19739265 16393943 11421492 10663392 16781746 15619225 11461765 10774834 17906064 12392966 10915739 15968718 18071297 16177239 | |
| MESH:D056487 | Drug-Induced Liver Injury, Chronic | Acetaminophen | 4.96 | 19426721 | |
| MESH:D004487 | Edema | pirinixic acid | 2.96 | 12083418 | |
| MESH:D005234 | Fatty Liver | pirinixic acid | 3.25 | 19236843 20131406 | |
| MESH:D005756 | Gastritis | Acetaminophen | 4.54 | 16983495 | |
| MESH:D006333 | Heart Failure | pirinixic acid | 2.78 | 20558911 | |
| MESH:D006529 | Hepatomegaly | pirinixic acid | 3.64 | 19772884 19176532 18467677 16221962 | |
| MESH:D006930 | Hyperalgesia | Acetaminophen | 3.06 | 16870215 | |
| MESH:D006943 | Hyperglycemia | pirinixic acid | 3.63 | 20558911 | |
| MESH:D007333 | Insulin Resistance | pirinixic acid | 2.90 | 16306350 | |
| MESH:D007674 | Kidney Diseases | Acetaminophen | 2.42 | 12587719 15629191 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | pirinixic acid | 1.35 | 15474484 | |
| MESH:D008107 | Liver Diseases | Acetaminophen | 4.56 | 16610002 12969438 16611625 19014921 12587719 19460945 11587558 19784758 | |
| MESH:D008107 | Liver Diseases | Lindane | 4.56 | 1715830 | |
| MESH:D017114 | Liver Failure, Acute | Acetaminophen | 3.68 | 16871587 17185352 | |
| MESH:D008113 | Liver Neoplasms | pirinixic acid | 1.94 | 20007298 16377806 15890375 | |
| MESH:D008546 | Melanoma, Experimental | Acetaminophen | 4.22 | 19513568 | |
| MESH:D009135 | Muscular Diseases | pirinixic acid | 4.16 | 16239165 | |
| MESH:D009203 | Myocardial Infarction | pirinixic acid | 2.29 | 19151258 | |
| MESH:D015428 | Myocardial Reperfusion Injury | pirinixic acid | 3.29 | 16411023 | |
| MESH:D009369 | Neoplasms | Lindane | 5.88 | 12807735 16818664 | |
| MESH:D009369 | Neoplasms | pirinixic acid | 5.88 | 17405874 | |
| MESH:D019636 | Neurodegenerative Diseases | Acetaminophen | 3.26 | 18514411 | |
| MESH:D009765 | Obesity | pirinixic acid | 1.89 | 20558911 | |
| MESH:D010146 | Pain | Acetaminophen | 2.77 | 16870215 | |
| MESH:D011471 | Prostatic Neoplasms | Lindane | 4.10 | 12661182 14688026 | |
| MESH:D015427 | Reperfusion Injury | pirinixic acid | 2.56 | 19058328 | |
| MESH:D012640 | Seizures | Lindane | 3.90 | 7539098 15475178 12842176 | |
| MESH:D014581 | Urticaria | Acetaminophen | 3.50 | 10982225 |
| No data |