AutismKB 2.0

Annotation Detail for PARD3B


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Basic Information Top
Gene Symbol:PARD3B ( ALS2CR19,MGC16131,PAR3B,PAR3L,PAR3LC,PAR3beta,Par3Lb )
Gene Full Name: par-3 partitioning defective 3 homolog B (C. elegans)
Band: 2q33.3
Quick LinksEntrez ID:117583; OMIM: NA; Uniprot ID:PAR3L_HUMAN; ENSEMBL ID: ENSG00000116117; HGNC ID: 14446
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
No data
No data
Desease Name
knee osteoarthritis
METABOLIC
Desease Name
Knee osteoarthritis
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C009505 4,4'-diaminodiphenylmethane 4,4'-diaminodiphenylmethane affects the expression of PARD3B mRNAaffects expression 18648102
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000236 Adenoma 4,4'-diaminodiphenylmethane 3.023712494
MESH:D001660 Biliary Tract Diseases 4,4'-diaminodiphenylmethane 6.441440618 11289319
MESH:D006528 Carcinoma, Hepatocellular 4,4'-diaminodiphenylmethane 1.797296757 3581430
MESH:D002292 Carcinoma, Renal Cell 4,4'-diaminodiphenylmethane 2.887296757
MESH:D002471 Cell Transformation, Neoplastic 4,4'-diaminodiphenylmethane 3.117505956
MESH:D002779 Cholestasis 4,4'-diaminodiphenylmethane 3.559022650 19486331
MESH:D017449 Dermatitis, Allergic Contact 4,4'-diaminodiphenylmethane 3.7011906362 18759878 8970840 12868966 2524372 14531868 11298694 8156756
MESH:D003877 Dermatitis, Contact 4,4'-diaminodiphenylmethane 4.192952479 3621924
MESH:D056486 Drug-Induced Liver Injury 4,4'-diaminodiphenylmethane 2.0616192314 18289764 18692083 9653073 1440618 9022650 6482804 11289319 9328219 18648102 6679447 8291058 7440962
MESH:D004938 Esophageal Neoplasms 4,4'-diaminodiphenylmethane 2.203581430
MESH:D005350 Fibroma 4,4'-diaminodiphenylmethane 6.446705139
MESH:D006042 Goiter 4,4'-diaminodiphenylmethane 4.737505956
MESH:D006505 Hepatitis 4,4'-diaminodiphenylmethane 4.306705139
MESH:D006965 Hyperplasia 4,4'-diaminodiphenylmethane 4.8515034207
MESH:D007565 Jaundice 4,4'-diaminodiphenylmethane 6.449022650 8074119
MESH:D007680 Kidney Neoplasms 4,4'-diaminodiphenylmethane 3.456582329
MESH:D008105 Liver Cirrhosis, Biliary 4,4'-diaminodiphenylmethane 3.509327722 15034207
MESH:D008114 Liver Neoplasms, Experimental 4,4'-diaminodiphenylmethane 2.833712494 598648 6587162 1399818
MESH:D009362 Neoplasm Metastasis 4,4'-diaminodiphenylmethane 2.633581430
MESH:D009436 Neural Tube Defects 4,4'-diaminodiphenylmethane 3.246679447
MESH:D009784 Occupational Diseases 4,4'-diaminodiphenylmethane 3.996482804 4026338
MESH:D009902 Optic Neuritis 4,4'-diaminodiphenylmethane 6.443988306
MESH:D010212 Papilloma 4,4'-diaminodiphenylmethane 4.397296757
MESH:D010787 Photosensitivity Disorders 4,4'-diaminodiphenylmethane 5.896228378
MESH:D012162 Retinal Degeneration 4,4'-diaminodiphenylmethane 3.783692021
MESH:D013964 Thyroid Neoplasms 4,4'-diaminodiphenylmethane 3.313712494 6582329 6587162 1399818 7505956
MESH:D001749 Urinary Bladder Neoplasms 4,4'-diaminodiphenylmethane 2.438074119
No data
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA162398721
    • No data
    Releated disease ID Related disease Name
    PA443937Drug Toxicity
    PA446155Precursor Cell Lymphoblastic Leukemia-Lymphoma
    PA164925725Toxic liver disease
    PA447021Osteoarthritis, Knee
    Releated drug ID Related drug Name
    PA452621antineoplastic agents
    Drug Bank Top

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    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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