Annotation Detail for OLFM3
Basic Information Top
| Gene Symbol: | OLFM3 ( NOE3,NOELIN3,NOELIN3_V1,NOELIN3_V2,NOELIN3_V3,NOELIN3_V4,NOELIN3_V5,NOELIN3_V6,OPTIMEDIN ) |
|---|---|
| Gene Full Name: | olfactomedin 3 |
| Band: | 1p21.1 |
| Quick Links | Entrez ID:118427; OMIM: 607567; Uniprot ID:NOE3_HUMAN; ENSEMBL ID: ENSG00000118733; HGNC ID: 17990 |
| Relate to Another Database: | SFARIGene; denovo-db |
Related Pathway Information| Chemical ID | Chemical Name | Interaction | Interaction Action | Publication |
|---|---|---|---|---|
| D000082 | Acetaminophen | Acetaminophen affects the expression of OLFM3 mRNA | affects expression | 17562736 |
| D000643 | Ammonium Chloride | Ammonium Chloride affects the expression of OLFM3 mRNA | affects expression | 16483693 |
| C014707 | nitrosobenzylmethylamine | nitrosobenzylmethylamine results in increased expression of OLFM3 mRNA | increases expression | 17616710 |
| C006253 | pirinixic acid | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of OLFM3 mRNA | affects binding|decreases expression|increases activity | 19710929 |
| Disease ID | Disease Name | Direct Evidence | Inference Chemical Name | Inference Score | Publication |
|---|---|---|---|---|---|
| MESH:D000138 | Acidosis | Ammonium Chloride | 4.19 | 18287403 | |
| MESH:D055371 | Acute Lung Injury | pirinixic acid | 3.58 | 18653653 | |
| MESH:D018248 | Adenoma, Liver Cell | pirinixic acid | 4.11 | 16434500 | |
| MESH:D000799 | Angioedema | Acetaminophen | 4.57 | 10982225 | |
| MESH:D001321 | Autistic Disorder | Acetaminophen | 1.40 | 18445737 | |
| MESH:D001778 | Blood Coagulation Disorders | pirinixic acid | 3.57 | 19483382 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Acetaminophen | 1.41 | 3084413 | |
| MESH:D002386 | Cataract | Acetaminophen | 2.79 | 10977129 | |
| MESH:D002779 | Cholestasis | pirinixic acid | 3.12 | 19176532 | |
| MESH:D003876 | Dermatitis, Atopic | pirinixic acid | 2.57 | 18249437 | |
| MESH:D056486 | Drug-Induced Liver Injury | Acetaminophen | 1.67 | 17562736 15968718 12540782 19085960 11421492 14986274 14550746 18071297 15619225 11739529 17522070 16177239 10663392 14725611 19370779 17906064 12594235 11461765 12153990 16781746 2444490 12705907 12392966 11743745 19420014 16109766 11529661 12958197 19923254 11834606 19164858 16227642 16393943 16081117 16485898 19416960 10774834 10915739 11287661 19739265 18713872 | |
| MESH:D056487 | Drug-Induced Liver Injury, Chronic | Acetaminophen | 4.82 | 19426721 | |
| MESH:D004487 | Edema | pirinixic acid | 2.90 | 12083418 | |
| MESH:D004938 | Esophageal Neoplasms | nitrosobenzylmethylamine | 2.85 | 15547733 16704527 16510608 15623463 16805852 15547721 15150132 15264214 15878914 | |
| MESH:D005234 | Fatty Liver | pirinixic acid | 3.19 | 20131406 19236843 | |
| MESH:D005756 | Gastritis | Acetaminophen | 4.40 | 16983495 | |
| MESH:D006333 | Heart Failure | pirinixic acid | 2.76 | 20558911 | |
| MESH:D006529 | Hepatomegaly | pirinixic acid | 3.55 | 16221962 18467677 19772884 19176532 | |
| MESH:D006930 | Hyperalgesia | Acetaminophen | 3.02 | 16870215 | |
| MESH:D006943 | Hyperglycemia | pirinixic acid | 3.58 | 20558911 | |
| MESH:D007333 | Insulin Resistance | pirinixic acid | 2.87 | 16306350 | |
| MESH:D007674 | Kidney Diseases | Acetaminophen | 2.40 | 15629191 12587719 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | pirinixic acid | 1.35 | 15474484 | |
| MESH:D008107 | Liver Diseases | Acetaminophen | 1.70 | 16611625 19460945 11587558 12969438 19784758 12587719 19014921 16610002 | |
| MESH:D017114 | Liver Failure, Acute | Acetaminophen | 3.63 | 16871587 17185352 | |
| MESH:D008113 | Liver Neoplasms | pirinixic acid | 1.93 | 20007298 16377806 15890375 | |
| MESH:D008546 | Melanoma, Experimental | Acetaminophen | 4.13 | 19513568 | |
| MESH:D009135 | Muscular Diseases | pirinixic acid | 4.07 | 16239165 | |
| MESH:D009203 | Myocardial Infarction | pirinixic acid | 2.27 | 19151258 | |
| MESH:D015428 | Myocardial Reperfusion Injury | pirinixic acid | 3.25 | 16411023 | |
| MESH:D009369 | Neoplasms | pirinixic acid | 2.11 | 17405874 | |
| MESH:D019636 | Neurodegenerative Diseases | Acetaminophen | 3.21 | 18514411 | |
| MESH:D009765 | Obesity | pirinixic acid | 1.88 | 20558911 | |
| MESH:D010146 | Pain | Acetaminophen | 2.73 | 16870215 | |
| MESH:D015427 | Reperfusion Injury | pirinixic acid | 2.55 | 19058328 | |
| MESH:D013274 | Stomach Neoplasms | nitrosobenzylmethylamine | 2.33 | 17575124 12958204 | |
| MESH:D014581 | Urticaria | Acetaminophen | 3.44 | 10982225 |
| No data |