AutismKB 2.0

Annotation Detail for FAT3


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Basic Information Top
Gene Symbol:FAT3 ( CDHF15,CDHR10,KIAA1989 )
Gene Full Name: FAT tumor suppressor homolog 3 (Drosophila)
Band: 11q14.3
Quick LinksEntrez ID:120114; OMIM: 612483; Uniprot ID:FAT3_HUMAN; ENSEMBL ID: ENSG00000165323; HGNC ID: 23112
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
No data
No data
No data
Pathway IDPathway Name
P00012Cadherin signaling pathway
P00057Wnt signaling pathway
No data
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000643 Ammonium Chloride Ammonium Chloride affects the expression of FAT3 mRNAaffects expression 16483693
D001241 Aspirin Aspirin results in increased expression of FAT3 mRNAincreases expression 11906190
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000138 Acidosis Ammonium Chloride 4.4418287403
MESH:D055963 Asthma, Aspirin-Induced Aspirin 5.1312372130 20485159
MESH:D001932 Brain Neoplasms Aspirin 4.9215481559
MESH:D001943 Breast Neoplasms Aspirin 3.1715161893
MESH:D003110 Colonic Neoplasms Aspirin 3.0412411196
MESH:D015179 Colorectal Neoplasms Aspirin 2.7517047198
MESH:D004487 Edema Aspirin 4.4317259670
MESH:D005909 Glioblastoma Aspirin 4.2512870263
MESH:D006261 Headache Aspirin 6.0315240983
MESH:D012001 Hyperacusis Aspirin 6.8315240983
MESH:D008881 Migraine Disorders Aspirin 4.4115240983
MESH:D009203 Myocardial Infarction Aspirin 3.7112692751
MESH:D009325 Nausea Aspirin 6.2815240983
MESH:D010003 Osteoarthritis Aspirin 4.327009135
MESH:D010146 Pain Aspirin 4.286995502 6363464
MESH:D010438 Peptic Ulcer Hemorrhage Aspirin 6.4311156591
MESH:D020795 Photophobia Aspirin 6.8315240983
MESH:D012220 Rhinitis Aspirin 4.8812372130
MESH:D012851 Sinus Thrombosis, Intracranial Aspirin 6.0312269725
MESH:D020521 Stroke Aspirin 4.7816403987
MESH:D013927 Thrombosis Aspirin 4.9817672075
MESH:D014581 Urticaria Aspirin 5.0420485159 10982225
No data
Pharmacogenomics Knowledge Base Top
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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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