AutismKB 2.0

Annotation Detail for CCR1


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:CCR1 ( CD191,CKR-1,CKR1,CMKBR1,HM145,MIP1aR,SCYAR1 )
Gene Full Name: chemokine (C-C motif) receptor 1
Band: 3p21.31
Quick LinksEntrez ID:1230; OMIM: 601159; Uniprot ID:CCR1_HUMAN; ENSEMBL ID: ENSG00000163823; HGNC ID: 1602
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa04062Chemokine signaling pathway
hsa04060Cytokine-cytokine receptor interaction
Pathway IDPathway Name
Signaling by GPCR
No data
Pathway IDPathway Name
P00031Inflammation mediated by chemokine and cytokine signaling pathway
No data
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1831Prostate cancer
1901Endometriosis
1976Squamous cell cancer
2022Liver cancer
2074Asthma
2099Hepatitis B
2100Hepatitis C
2237Neoplasm metastasis
Desease Name
Celiac Disease
IMMUNE
Desease Name
Celiac disease
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C063609 1,2-dimethyl-4-nitrobenzene 1,2-dimethyl-4-nitrobenzene results in decreased expression of CCR1 mRNAdecreases expression 19784758
C027576 4-hydroxy-2-nonenal 4-hydroxy-2-nonenal results in decreased expression of CCR1 mRNAdecreases expression 12419474
D000082 Acetaminophen Acetaminophen affects the expression of CCR1 mRNAaffects expression 17562736
D000082 Acetaminophen Acetaminophen affects the expression of CCR1 mRNAaffects expression 19784758
D000082 Acetaminophen Acetaminophen results in decreased expression of CCR1 mRNAdecreases expression 19784758
D000082 Acetaminophen Acetaminophen results in increased expression of CCR1 mRNAincreases expression 19784758
D000643 Ammonium Chloride Ammonium Chloride affects the expression of CCR1 mRNAaffects expression 16483693
D001151 Arsenic [Arsenic co-treated with Fluorides] results in decreased expression of CCR1 mRNAaffects cotreatment|decreases expression 19962721
D001151 Arsenic Arsenic results in decreased expression of CCR1 mRNAdecreases expression 19962721
D001151 Arsenic Arsenic results in decreased expression of CCR1 mRNAdecreases expression 19654921
C015001 arsenite arsenite results in decreased expression of CCR1 mRNAdecreases expression 18191166
C002791 bismuth tripotassium dicitrate bismuth tripotassium dicitrate results in increased expression of CCR1 mRNAincreases expression 15912405
D001966 Bromine Bromine results in increased expression of CCR1 mRNAincreases expression 18790026
D002251 Carbon Tetrachloride Carbon Tetrachloride results in decreased expression of CCR1 mRNAdecreases expression 19784758
D017373 Cyproterone Acetate [Ethinyl Estradiol co-treated with Cyproterone Acetate] results in increased expression of CCR1 proteinaffects cotreatment|increases expression 10770211
D002945 Cisplatin Cisplatin results in increased expression of CCR1 mRNAincreases expression 15814532
D002945 Cisplatin pirinixic acid inhibits the reaction [Cisplatin results in increased expression of CCR1 mRNA]decreases reaction|increases expression 15814532
D004997 Ethinyl Estradiol [Ethinyl Estradiol co-treated with Cyproterone Acetate] results in increased expression of CCR1 proteinaffects cotreatment|increases expression 10770211
D004997 Ethinyl Estradiol Ethinyl Estradiol results in decreased expression of CCR1 mRNAdecreases expression 15885639
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of CCR1 mRNAaffects expression 15212814
D005459 Fluorides [Arsenic co-treated with Fluorides] results in decreased expression of CCR1 mRNAaffects cotreatment|decreases expression 19962721
D005459 Fluorides Fluorides results in decreased expression of CCR1 mRNAdecreases expression 19962721
D006861 Hydrogen Peroxide Hydrogen Peroxide results in decreased expression of CCR1 mRNAdecreases expression 12419474
C051890 irinotecan irinotecan metabolite results in increased expression of CCR1 mRNAincreases expression 15956246
C051890 irinotecan irinotecan results in increased expression of CCR1 mRNAincreases expression 15956246
D009151 Mustard Gas Mustard Gas results in increased expression of CCR1 mRNAincreases expression 15674843
18955075
D009151 Mustard Gas Mustard Gas results in increased expression of CCR1 mRNAincreases expression 18988085
D009578 Nitrobenzenes Nitrobenzenes analog results in decreased expression of CCR1 mRNAdecreases expression 19784758
C006253 pirinixic acid pirinixic acid inhibits the reaction [Cisplatin results in increased expression of CCR1 mRNA]decreases reaction|increases expression 15814532
C006253 pirinixic acid pirinixic acid results in decreased expression of CCR1 mRNAdecreases expression 16985257
C025299 polyphenols polyphenols results in decreased expression of CCR1 mRNAdecreases expression 16293270
D020058 Styrene Styrene results in decreased expression of CCR1 mRNAdecreases expression 15212811
D020058 Styrene Styrene results in decreased expression of CCR1 proteindecreases expression 15212811
C004648 testosterone enanthate testosterone enanthate affects the expression of CCR1 mRNAaffects expression 17440010
D013853 Thioacetamide Thioacetamide results in decreased expression of CCR1 mRNAdecreases expression 19784758
D014212 Tretinoin Tretinoin results in increased expression of CCR1 mRNAincreases expression 19828696
C015559 trimellitic anhydride trimellitic anhydride results in increased expression of CCR1 mRNAincreases expression 16141432
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000138 Acidosis Ammonium Chloride 3.3918287403
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.7717505938
MESH:D058186 Acute Kidney Injury Cisplatin 3.8015814532 12690470 17670903
MESH:D055371 Acute Lung Injury pirinixic acid 2.9618653653
MESH:D000230 Adenocarcinoma Cisplatin 4.3117638652 11798837
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 4.3114692618
MESH:D018248 Adenoma, Liver Cell pirinixic acid 3.3116434500
MESH:D018246 Adrenocortical Adenoma Arsenic 5.0417306315
MESH:D000505 Alopecia Tretinoin 3.4815955085
MESH:D000690 Amyotrophic Lateral Sclerosis 4-hydroxy-2-nonenal 4.0010965797
MESH:D000799 Angioedema Acetaminophen 3.6710982225
MESH:D020261 Arsenic Poisoning Arsenic 2.8212569548 16835338 18414634 16251483
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.2911256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 6.8615885639
MESH:D001169 Arthritis, Experimental Tretinoin 6.8616412693
MESH:D001172 Arthritis, Rheumatoid Tretinoin 2.2316292516
MESH:D001249 Asthma Mustard Gas 7.8210378619
MESH:D001249 Asthma Tretinoin 7.8216456186
MESH:D001249 Asthma trimellitic anhydride 7.8216141432
MESH:D050197 Atherosclerosis Arsenic 3.1519371607 12928151
MESH:D001321 Autistic Disorder Acetaminophen 1.4318445737
MESH:D001471 Barrett Esophagus Tretinoin 4.2416935849
MESH:D001768 Blister Mustard Gas 4.9919167455
MESH:D001778 Blood Coagulation Disorders pirinixic acid 14.5219483382
MESH:D001778 Blood Coagulation Disorders Thioacetamide 14.5219483382
MESH:D001778 Blood Coagulation Disorders Tretinoin 14.5216206674 16197459
MESH:D019046 Bone Marrow Neoplasms Cisplatin 4.7114601052
MESH:D001943 Breast Neoplasms Cisplatin 2.2119526202 18382427
MESH:D001943 Breast Neoplasms Styrene 2.2115986119
MESH:D001943 Breast Neoplasms Tretinoin 2.2116873071 16443354 16166294
MESH:D001989 Bronchiolitis Obliterans Mustard Gas 4.9915286001
MESH:D029481 Bronchitis, Chronic Mustard Gas 4.8010378619 17687719
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 4.4216813970
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 3.6116124888 16097048 16192424 18705752 16011737 15700767 16050911 16227642 15673190 3786805 10355542 15721981
MESH:D002280 Carcinoma, Basal Cell Arsenic 3.5017687452 15504454
MESH:D018236 Carcinoma, Embryonal Tretinoin 4.9916168501
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 11.033084413
MESH:D006528 Carcinoma, Hepatocellular Arsenic 11.0317306315 16507464
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 11.0318788625
MESH:D006528 Carcinoma, Hepatocellular Cisplatin 11.0317982673
MESH:D006528 Carcinoma, Hepatocellular Thioacetamide 11.0317997003
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 11.031917145
MESH:D002289 Carcinoma, Non-Small-Cell Lung Cisplatin 2.9812023789 16685392
MESH:D002294 Carcinoma, Squamous Cell Arsenic 7.3617687452 18922899 15504454
MESH:D002294 Carcinoma, Squamous Cell Cisplatin 7.3617066447 6189445 18337622
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 7.3616096774 16051514
MESH:D002295 Carcinoma, Transitional Cell Arsenic 3.9318640142
MESH:D002318 Cardiovascular Diseases Arsenic 7.1917938729 15738583 19152805
MESH:D002318 Cardiovascular Diseases Hydrogen Peroxide 7.1916936243
MESH:D002340 Carotid Artery Diseases Arsenic 4.1618022660 16973168
MESH:D002386 Cataract Acetaminophen 6.8910977129
MESH:D002386 Cataract Tretinoin 6.8917460283
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 4.4216129372
MESH:D018281 Cholangiocarcinoma Thioacetamide 4.1418291259
MESH:D002779 Cholestasis Ethinyl Estradiol 7.3215861022 17681005 17110522 11677210 17333356 16105132 16919318
MESH:D002779 Cholestasis pirinixic acid 7.3219176532
MESH:D002822 Choriocarcinoma Tretinoin 4.9916461808
MESH:D002972 Cleft Palate Tretinoin 2.609407595
MESH:D003092 Colitis Tretinoin 3.5317035595
MESH:D003110 Colonic Neoplasms arsenite 5.8315037631
MESH:D003110 Colonic Neoplasms irinotecan 5.8317287894 17725105
MESH:D003110 Colonic Neoplasms polyphenols 5.8316293270
MESH:D015179 Colorectal Neoplasms Cisplatin 2.8115273666
MESH:D015179 Colorectal Neoplasms irinotecan 2.8117454858 16391804 18509181 18259882 16303861 17159606 15273666
MESH:D019465 Craniofacial Abnormalities Tretinoin 1.819125849 9142499 14991402 9211117 8800419 9224671 10589399 16925845 9664655 17551590
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.3518249437
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 8.6119420014 11287661 18713872 11421492 11739529 14986274 11743745 14550746 10774834 14725611 12594235 16227642 19164858 19416960 15619225 12540782 12392966 12153990 16081117 11529661 19923254 10915739 17562736 11461765 19085960 16781746 2444490 19739265 16393943 17906064 16177239 12705907 19370779 18071297 16485898 17522070 16109766 10663392 15968718 11834606 12958197
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 8.617120509 7179309 4309450 6884620 7440962 2869522 3786805 11566570 15998439 19336974 9327722 10092053 3732212 15027814 10915739 17522070 21278145 19085960 15968718 6623471 16177239 16227642
MESH:D056486 Drug-Induced Liver Injury polyphenols 8.6119370779
MESH:D056486 Drug-Induced Liver Injury Thioacetamide 8.6112963478
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 3.9319426721
MESH:D004362 Drug Toxicity Cisplatin 3.7312649298 15033597 12231392 19839026
MESH:D004487 Edema Mustard Gas 6.3711428647 11402378 9260866 11428631
MESH:D004487 Edema pirinixic acid 6.3712083418
MESH:D004489 Edema, Cardiac Tretinoin 4.2918230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 3.0212538720
MESH:D016889 Endometrial Neoplasms Tretinoin 3.0016569247
MESH:D004890 Erythema Mustard Gas 4.999357497
MESH:D004938 Esophageal Neoplasms Cisplatin 2.7415173087 17638652 15464296 16481741 16785472
MESH:D005124 Eye Abnormalities Tretinoin 3.459664655 16938888
MESH:D005218 Fat Necrosis Thioacetamide 5.5516456712
MESH:D005234 Fatty Liver arsenite 17.4918296743
MESH:D005234 Fatty Liver Carbon Tetrachloride 17.4915959796 16045604 12795759 12631006 17595544 19224547 61145 16239168
MESH:D005234 Fatty Liver Ethinyl Estradiol 17.4915345470
MESH:D005234 Fatty Liver pirinixic acid 17.4920131406 19236843
MESH:D005355 Fibrosis arsenite 13.9218296743
MESH:D005355 Fibrosis Carbon Tetrachloride 13.9218705752
MESH:D005355 Fibrosis Tretinoin 13.9217994277
MESH:D005534 Foot Diseases Arsenic 5.396392382
MESH:D005756 Gastritis Acetaminophen 3.5016983495
MESH:D005909 Glioblastoma Tretinoin 2.9017312396
MESH:D006258 Head and Neck Neoplasms Cisplatin 7.5315102660 15464296
MESH:D006258 Head and Neck Neoplasms Tretinoin 7.5316096774
MESH:D034381 Hearing Loss Cisplatin 9.9919898482
MESH:D034381 Hearing Loss Styrene 9.9917420221
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 4.9916084493
MESH:D006319 Hearing Loss, Sensorineural Cisplatin 4.2815464296
MESH:D006330 Heart Defects, Congenital Tretinoin 2.8114991402 9664655
MESH:D006333 Heart Failure pirinixic acid 2.4320558911
MESH:D006501 Hepatic Encephalopathy Thioacetamide 4.4215929193 17276928 18665440
MESH:D006505 Hepatitis Carbon Tetrachloride 8.9319110552 19900420
MESH:D006505 Hepatitis Thioacetamide 8.9316456712
MESH:D006529 Hepatomegaly pirinixic acid 2.8319772884 18467677 16221962 19176532
MESH:D019247 HIV Wasting Syndrome testosterone enanthate 5.5717440010
MESH:D006689 Hodgkin Disease Cisplatin 3.4516200630 16170182
MESH:D006930 Hyperalgesia Acetaminophen 7.1716870215
MESH:D006930 Hyperalgesia Tretinoin 7.1716870215
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 4.3616899240
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 4.4016778211
MESH:D006943 Hyperglycemia pirinixic acid 3.0320558911
MESH:D017488 Hyperkeratosis, Epidermolytic Arsenic 4.3017050553
MESH:D006973 Hypertension Arsenic 2.819931084 11953799 16076760
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 3.9215338365
MESH:D006987 Hypesthesia Arsenic 5.3916093927
MESH:D007021 Hypospadias Ethinyl Estradiol 3.6416945680 16569931
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.3012013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 2.3717937319
MESH:D007249 Inflammation Mustard Gas 5.2017524151 9357497 8975870 11428647 9260866 11428631 11428620 11402378 16001271
MESH:D007249 Inflammation polyphenols 5.2016366677
MESH:D007333 Insulin Resistance pirinixic acid 2.5216306350
MESH:D007410 Intestinal Diseases Tretinoin 3.6017994277
MESH:D007569 Jaw Abnormalities Tretinoin 3.7417551590 15992940
MESH:D007642 Keratosis Arsenic 4.8212749816 16930632
MESH:D007673 Kidney Cortex Necrosis Cisplatin 4.9715464296
MESH:D007674 Kidney Diseases Acetaminophen 5.8012587719 15629191
MESH:D007674 Kidney Diseases Cisplatin 5.8019839026 15190930 12231392 12649298 18289764
MESH:D007676 Kidney Failure, Chronic Hydrogen Peroxide 4.1216518626
MESH:D007683 Kidney Tubular Necrosis, Acute Cisplatin 4.6211231351
MESH:D007938 Leukemia Tretinoin 2.6917143497
MESH:D007951 Leukemia, Myeloid Tretinoin 3.5416482212 19285840 16932348
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 2.0519850784 16294345 17596541
MESH:D015473 Leukemia, Promyelocytic, Acute Arsenic 7.3917339181
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 7.3917361223 16331271 16823087 16935935 17294898 16766008 9834237 17301526 12679006 19029980 16891316 16140955 17712046 19225113 17649720 15748426 16788101 19035177 19075265 17339181 17506722 17368321 17107899 19642359 17217047
MESH:D017880 Limb Deformities, Congenital Tretinoin 3.199224671
MESH:D008103 Liver Cirrhosis arsenite 6.5218296743
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 6.5221278145 16239168 11903743 11408273 17157831 16221502 17174718 16943688 17334410
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 4.8015818738 18395914 15123356 18472094 17761835 18006644 18429990 15370692 14716833 14512876 18251166 15730626 17976157 14620537 15959796 12546737 18156304 12649538 12632512 15673190 17721639 15925388 18339082 17557913 17900296 17869086 18279442 18472332 16097048 17481882 15052691 12632514 13678700 12898905 16027843 14748882 12667390 17698563 12958196 17922224 18263696 16136751 15362042 16638106 18376398 17805973 16011737 15338365 17640975 18412020 18395095 18054572 12586293 15931870 12741479 12389079 15996030 16248980 18205269 18210741 18420326 18277467 17708605 12445418 10355542 18481824 16033810 20821823 12445421 18166357 16192424 14716496 17631135 17565644 18418968 14724832 17714472 15650968 12609069 18705752 17525996 15057751 17766677 12666154 18187930 16015684 15876570 17823541 15893842 17944888 18317297 11481614 16116963
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 4.8015474484
MESH:D008106 Liver Cirrhosis, Experimental Thioacetamide 4.8018606216 11172339 18263696 15316131 12175628 15075984 17050028 14739098 12557150 12679928 16489207 12531686 15362042 18416461 17355460 18032466 18380797 18295389 15288472 17629604 18395095 15288473 10677585 15334695 16511523 16098781 12891558 11481614 15465738 15078482 16343077 15158331 17127702 15095483 18615449 15716488 17292413 18031379 12085344 15474484 16097051 11682029 16126171 18458672 16248980
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 4.8016248980 18397230
MESH:D008107 Liver Diseases marker/mechanism 19784758
MESH:D008107 Liver Diseases Acetaminophen 12.0619014921 16610002 12969438 11587558 19784758 12587719 19460945 16611625
MESH:D008107 Liver Diseases Arsenic 12.0611134558
MESH:D008107 Liver Diseases Carbon Tetrachloride 12.0615720792 16964402 15830285 17285989 16246199
MESH:D008107 Liver Diseases polyphenols 12.0616698588
MESH:D008107 Liver Diseases Thioacetamide 12.0618374380 16337175 15158337
MESH:D017093 Liver Failure Carbon Tetrachloride 3.9915123358
MESH:D017114 Liver Failure, Acute Acetaminophen 15.3816871587 17185352
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 15.3816899240 14706259
MESH:D017114 Liver Failure, Acute Thioacetamide 15.3817276928 15313186 15633222 12479984
MESH:D008113 Liver Neoplasms Arsenic 7.0916368122
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 7.0919294768
MESH:D008113 Liver Neoplasms pirinixic acid 7.0916377806 15890375 20007298
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 2.5112014681 15583823
MESH:D008171 Lung Diseases Mustard Gas 3.3418702808 18161513
MESH:D008175 Lung Neoplasms Arsenic 6.4317976673 19168569 17306315
MESH:D008175 Lung Neoplasms arsenite 6.4316809336
MESH:D008175 Lung Neoplasms Cisplatin 6.4317225452 11798837 6189445
MESH:D008175 Lung Neoplasms Mustard Gas 6.438781369 3148597
MESH:D008175 Lung Neoplasms Styrene 6.4312562636
MESH:D015674 Mammary Neoplasms, Animal Styrene 5.2812562636
MESH:D008527 Medulloblastoma Tretinoin 2.7217453147
MESH:D008545 Melanoma Cisplatin 3.4117023156 16432458 17761969 18505091 11135225 16809738 12883367 16248763 18332650 15577323 12393984 18176117 12374674
MESH:D008545 Melanoma Tretinoin 3.4116752155
MESH:D018328 Melanoma, Amelanotic Cisplatin 4.6015990972
MESH:D008546 Melanoma, Experimental Acetaminophen 3.4019513568
MESH:D008591 Meningomyelocele Tretinoin 4.2516940565
MESH:D008654 Mesothelioma Cisplatin 3.1817638057
MESH:D052016 Mucositis irinotecan 4.8417159606
MESH:D009135 Muscular Diseases pirinixic acid 3.3416239165
MESH:D009190 Myelodysplastic Syndromes Tretinoin 2.9817596541
MESH:D009203 Myocardial Infarction pirinixic acid 2.0719151258
MESH:D017202 Myocardial Ischemia Arsenic 3.8515371236
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 2.8116411023
MESH:D009362 Neoplasm Metastasis irinotecan 3.1018259882
MESH:D009369 Neoplasms Cisplatin 7.8016773208
MESH:D009369 Neoplasms pirinixic acid 7.8017405874
MESH:D009369 Neoplasms Tretinoin 7.8016946489 16594593
MESH:D009389 Neovascularization, Pathologic arsenite 4.2415738583
MESH:D009395 Nephritis, Interstitial Cisplatin 4.3215464296
MESH:D009421 Nervous System Malformations Tretinoin 3.619125849
MESH:D009436 Neural Tube Defects Arsenic 7.0616620997
MESH:D009436 Neural Tube Defects Tretinoin 7.069142499
MESH:D009447 Neuroblastoma Cisplatin 6.938761367
MESH:D009447 Neuroblastoma irinotecan 6.938761367
MESH:D019636 Neurodegenerative Diseases Acetaminophen 2.7318514411
MESH:D017599 Neuroectodermal Tumors Cisplatin 10.898761367
MESH:D017599 Neuroectodermal Tumors irinotecan 10.898761367
MESH:D020078 Neurogenic Inflammation Arsenic 4.2117056641
MESH:D009503 Neutropenia Mustard Gas 3.817688884 16761898
MESH:D009765 Obesity pirinixic acid 1.7720558911
MESH:D010051 Ovarian Neoplasms Arsenic 7.6917306315
MESH:D010051 Ovarian Neoplasms Cisplatin 7.6919769630 17225452 6897625 15464296
MESH:D010051 Ovarian Neoplasms Tretinoin 7.6916936753
MESH:D010146 Pain Acetaminophen 6.1316870215
MESH:D010146 Pain Tretinoin 6.1316870215
MESH:D010190 Pancreatic Neoplasms Cisplatin 5.2619003803
MESH:D010190 Pancreatic Neoplasms Tretinoin 5.2615976015
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.5311578682
MESH:D010212 Papilloma Hydrogen Peroxide 3.9212065085
MESH:D010523 Peripheral Nervous System Diseases Arsenic 9.5116093927
MESH:D010523 Peripheral Nervous System Diseases Cisplatin 9.5115464296
MESH:D016491 Peripheral Vascular Diseases Arsenic 4.826392382 15371236 16905509
MESH:D010787 Photosensitivity Disorders 4-hydroxy-2-nonenal 5.3311550810
MESH:D010997 Pleural Neoplasms Cisplatin 5.1717638057
MESH:D011041 Poisoning Mustard Gas 3.6415727166
MESH:D011471 Prostatic Neoplasms Arsenic 3.6616140617
MESH:D011507 Proteinuria Arsenic 8.7421343184
MESH:D011507 Proteinuria Tretinoin 8.7416636307
MESH:D011537 Pruritus Ethinyl Estradiol 8.9515861022 16919318
MESH:D011537 Pruritus Mustard Gas 8.9518058305
MESH:D011625 Pterygium Tretinoin 4.6216723453
MESH:D011658 Pulmonary Fibrosis Mustard Gas 2.8610334151 17894541 17620002 17266442 17720292
MESH:D051437 Renal Insufficiency Cisplatin 4.2415464296
MESH:D015427 Reperfusion Injury pirinixic acid 2.3019058328
MESH:D012130 Respiratory Hypersensitivity trimellitic anhydride 4.7520219652
MESH:D012208 Rhabdomyosarcoma Tretinoin 3.9416283617 16116481
MESH:D012512 Sarcoma, Ewing's Cisplatin 4.2614601052
MESH:D012871 Skin Diseases Arsenic 4.9917938729 16759981 17453740 16353154 19834688 18709164 16702368 15952646 17548696 17050553 6392382
MESH:D012871 Skin Diseases Mustard Gas 4.9915451306 12880345 16961503
MESH:D012878 Skin Neoplasms Arsenic 9.1415504454 16251483 17976673 17029826 19538983 17050553
MESH:D012878 Skin Neoplasms Hydrogen Peroxide 9.1412065085
MESH:D012878 Skin Neoplasms Tretinoin 9.1416467112
MESH:D055752 Small Cell Lung Carcinoma Cisplatin 5.1715464296
MESH:D013088 Spermatocele Ethinyl Estradiol 3.7716709447
MESH:D013274 Stomach Neoplasms Cisplatin 3.4218396642 15958060 17522103
MESH:D013274 Stomach Neoplasms irinotecan 3.4215723263
MESH:D013274 Stomach Neoplasms Tretinoin 3.4217261132
MESH:D013705 Temporomandibular Joint Disorders polyphenols 5.0817997062
MESH:D013736 Testicular Neoplasms Cisplatin 4.4715464296 17225452
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.4611994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.0115669648
MESH:D013964 Thyroid Neoplasms Tretinoin 2.9017045167 16026305
MESH:D014062 Tongue Neoplasms Tretinoin 3.6416051514
MESH:D014376 Tuberculosis Tretinoin 3.1216040207
MESH:D001749 Urinary Bladder Neoplasms Arsenic 5.2317306315 17976673 15987713 18640142 19322015 19429237 11144890
MESH:D001749 Urinary Bladder Neoplasms Cisplatin 5.2312973940 17225452 15464296
MESH:D014581 Urticaria Acetaminophen 2.8210982225
MESH:D002583 Uterine Cervical Neoplasms Cisplatin 9.0716803524
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 9.0716129372
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.1314692618
MESH:D014604 Uveal Neoplasms Tretinoin 4.4416752155
MESH:D014625 Vaginal Neoplasms Cisplatin 4.4415577323
MESH:D014652 Vascular Diseases Arsenic 4.5617056641
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.3814671159 15869587
MESH:D014820 Vitiligo Tretinoin 3.8916761959
MESH:D014839 Vomiting Cisplatin 4.5511897121
MESH:D009396 Wilms Tumor Tretinoin 3.8216287080
Pathway ID Pathway Name
KEGG:04062 Chemokine signaling pathway
KEGG:04060 Cytokine-cytokine receptor interaction
REACT:14797 Signaling by GPCR
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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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