AutismKB 2.0

Annotation Detail for SLC25A29


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Basic Information Top
Gene Symbol:SLC25A29 ( C14orf69,CACL,FLJ38975 )
Gene Full Name: solute carrier family 25, member 29
Band: 14q32.2
Quick LinksEntrez ID:123096; OMIM: NA; Uniprot ID:MCATL_HUMAN; ENSEMBL ID: ENSG00000197119; HGNC ID: 20116
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of SLC25A29 mRNAaffects expression 21346803
C009505 4,4'-diaminodiphenylmethane 4,4'-diaminodiphenylmethane results in decreased expression of SLC25A29 mRNAdecreases expression 18648102
D000082 Acetaminophen Acetaminophen affects the expression of SLC25A29 mRNAaffects expression 17562736
D019324 beta-Naphthoflavone [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of SLC25A29 mRNAaffects cotreatment|increases expression 18164116
D019259 Lamivudine [Zidovudine co-treated with Lamivudine] results in increased expression of SLC25A29 mRNAaffects cotreatment|increases expression 18313992
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of SLC25A29 mRNAaffects cotreatment|increases expression 18164116
C056507 gemcitabine gemcitabine results in increased expression of SLC25A29 mRNAincreases expression 17039268
C006253 pirinixic acid [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of SLC25A29 mRNAaffects binding|decreases expression|increases activity 19710929
D015215 Zidovudine [Zidovudine co-treated with Lamivudine] results in increased expression of SLC25A29 mRNAaffects cotreatment|increases expression 18313992
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000163 Acquired Immunodeficiency Syndrome Zidovudine 5.089612607
MESH:D055371 Acute Lung Injury pirinixic acid 3.3418653653
MESH:D000236 Adenoma 4,4'-diaminodiphenylmethane 11.873712494
MESH:D000236 Adenoma beta-Naphthoflavone 11.8719389873
MESH:D000236 Adenoma Diethylnitrosamine 11.8710737359 6695378
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 11.0617162532 19052882 16434500 19061943 18056438 17620307
MESH:D018248 Adenoma, Liver Cell pirinixic acid 11.0616434500
MESH:D000799 Angioedema Acetaminophen 4.1610982225
MESH:D001321 Autistic Disorder Acetaminophen 1.4018445737
MESH:D001660 Biliary Tract Diseases 4,4'-diaminodiphenylmethane 5.341440618 11289319
MESH:D001778 Blood Coagulation Disorders pirinixic acid 3.3519483382
MESH:D001943 Breast Neoplasms Diethylnitrosamine 2.5517474063
MESH:D001943 Breast Neoplasms gemcitabine 2.5518382427 17039268
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 6.7816705839
MESH:D006528 Carcinoma, Hepatocellular 4,4'-diaminodiphenylmethane 6.787296757 3581430
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 6.783084413
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 6.7819335982 17138121 18785209 20935162 18978308 11831363 16681979 18210153 16540662 17978847 16807293 16569478 10737359 20007298 19208518 16288022 20101231 19822196 18691550 20524982 20512989 16878318 16830150 19052882 18056438 20727157 18971187 20214788 19394651 19171122 3581430 16935385 19383236 17428255 20084675 17173139 18665156 19539802 17162532 18506893 16698587 18788625 19418558 17761372 19107877 16328049 10672840 3084413 20432363 21159647 17055752 16502159 18494052 16779866 19919837 18393292 19519916 20514400 19701751
MESH:D002292 Carcinoma, Renal Cell 4,4'-diaminodiphenylmethane 2.767296757
MESH:D002386 Cataract Acetaminophen 2.6910977129
MESH:D002471 Cell Transformation, Neoplastic 4,4'-diaminodiphenylmethane 7.157505956
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 7.1517174075 7505956 2727394 21159647
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 3.8719052882
MESH:D002779 Cholestasis 4,4'-diaminodiphenylmethane 8.3519486331 9022650
MESH:D002779 Cholestasis pirinixic acid 8.3519176532
MESH:D003490 Cyanosis 2,4-dinitrotoluene 4.2718551238
MESH:D017449 Dermatitis, Allergic Contact 4,4'-diaminodiphenylmethane 3.0614531868 18759878 11298694 12868966 8970840 8156756 2524372 11906362
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.5118249437
MESH:D003877 Dermatitis, Contact 4,4'-diaminodiphenylmethane 3.713621924 2952479
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 2.2320387270
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 9.4118551238 21346803
MESH:D056486 Drug-Induced Liver Injury 4,4'-diaminodiphenylmethane 9.419653073 1440618 18289764 11289319 18692083 18648102 9022650 16192314 8291058 7440962 6482804 6679447 9328219
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 9.4119370779 17906064 2444490 16081117 10774834 12705907 11421492 11287661 14550746 16781746 19923254 14725611 16177239 10663392 17522070 11461765 15619225 16109766 16227642 18713872 11834606 19739265 12540782 18071297 11529661 19416960 16393943 10915739 14986274 12392966 12153990 19085960 11739529 15968718 12958197 12594235 11743745 16485898 19164858 17562736 19420014
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 9.4119107877
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.4219426721
MESH:D004362 Drug Toxicity Lamivudine 9.2915040536
MESH:D004362 Drug Toxicity Zidovudine 9.2915040536
MESH:D004487 Edema pirinixic acid 2.6812083418
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 5.4416302075
MESH:D004938 Esophageal Neoplasms 4,4'-diaminodiphenylmethane 2.153581430
MESH:D005234 Fatty Liver Diethylnitrosamine 14.4320387270 21071580
MESH:D005234 Fatty Liver pirinixic acid 14.4319236843 20131406
MESH:D005234 Fatty Liver Zidovudine 14.4318299183
MESH:D005350 Fibroma 4,4'-diaminodiphenylmethane 5.346705139
MESH:D005756 Gastritis Acetaminophen 3.9916983495
MESH:D006042 Goiter 4,4'-diaminodiphenylmethane 4.267505956
MESH:D006333 Heart Failure pirinixic acid 2.6520558911
MESH:D006402 Hematologic Diseases Zidovudine 4.9312579204
MESH:D006505 Hepatitis 4,4'-diaminodiphenylmethane 3.756705139
MESH:D006509 Hepatitis B Lamivudine 5.3117703166
MESH:D019694 Hepatitis B, Chronic Lamivudine 5.3112044531 15631357 15274664 16476009 15309715
MESH:D006529 Hepatomegaly pirinixic acid 3.2516221962 19176532 19772884 18467677
MESH:D015658 HIV Infections Lamivudine 7.3811141242 20032539 17530837 9296927
MESH:D015658 HIV Infections Zidovudine 7.3811698656 11363243 11141242 20032539 17358032
MESH:D006930 Hyperalgesia Acetaminophen 2.8616870215
MESH:D006943 Hyperglycemia pirinixic acid 3.3820558911
MESH:D006965 Hyperplasia 4,4'-diaminodiphenylmethane 4.2015034207
MESH:D007249 Inflammation Diethylnitrosamine 2.4718785209
MESH:D007333 Insulin Resistance pirinixic acid 2.7616306350
MESH:D007565 Jaundice 4,4'-diaminodiphenylmethane 5.348074119 9022650
MESH:D007674 Kidney Diseases Acetaminophen 2.3015629191 12587719
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 13.5316705839
MESH:D007680 Kidney Neoplasms 4,4'-diaminodiphenylmethane 13.536582329
MESH:D007680 Kidney Neoplasms Zidovudine 13.5312579204
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell Zidovudine 4.6220370541
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 2.9318665156 18522880 19638242 20032147 18407596
MESH:D008105 Liver Cirrhosis, Biliary 4,4'-diaminodiphenylmethane 3.3115034207 9327722
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 1.3515474484
MESH:D008107 Liver Diseases Acetaminophen 4.0511587558 12969438 12587719 16611625 16610002 19014921 19784758 19460945
MESH:D008107 Liver Diseases Diethylnitrosamine 4.0517034775
MESH:D017114 Liver Failure, Acute Acetaminophen 3.4317185352 16871587
MESH:D008113 Liver Neoplasms beta-Naphthoflavone 7.8721295105 19389873
MESH:D008113 Liver Neoplasms Diethylnitrosamine 7.8720434301 21278145 19551842 19426721 19996281 16942905 10737359 18754104 20583210 19638242 19255062 12112319 20101389 12771043 18978307 20137499 20492335 19294768 21167192 19499222 19850985 9163691 20501860 19833225 21047994 19256749 21071580 19073162 2862719 19690152 20118626 19812893 15175105 18644402 20405173 20452335 18648771 19427195 19090486 18977376 19642983 19254457 15885732 2422723
MESH:D008113 Liver Neoplasms pirinixic acid 7.8720007298 16377806 15890375
MESH:D008114 Liver Neoplasms, Experimental 4,4'-diaminodiphenylmethane 10.63598648 3712494 1399818 6587162
MESH:D008114 Liver Neoplasms, Experimental beta-Naphthoflavone 10.6318164116
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 10.6316842330 18164116 17942915 18253720 3124819 19539802 18093689 18775883 9362446 19009564 19004024 16267830 18308698 18544905 17854601 19126423 18282651 18079962 21159647 2563599 19519916 17174075
MESH:D008175 Lung Neoplasms Diethylnitrosamine 2.7621163286 6695378 20970405 20512841
MESH:D008175 Lung Neoplasms Zidovudine 2.7618800350
MESH:D008546 Melanoma, Experimental Acetaminophen 3.8319513568
MESH:D048629 Micronuclei, Chromosome-Defective Zidovudine 6.1617358032
MESH:D009135 Muscular Diseases pirinixic acid 3.7616239165
MESH:D009203 Myocardial Infarction pirinixic acid 2.2119151258
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 3.1016411023
MESH:D009336 Necrosis 2,4-dinitrotoluene 4.1418551238
MESH:D009362 Neoplasm Metastasis 4,4'-diaminodiphenylmethane 5.943581430
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 5.943581430 9029167
MESH:D009369 Neoplasms pirinixic acid 2.0317405874
MESH:D009436 Neural Tube Defects 4,4'-diaminodiphenylmethane 3.046679447
MESH:D019636 Neurodegenerative Diseases Acetaminophen 8.7618514411
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 8.7620387270
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 5.4420387270
MESH:D009765 Obesity pirinixic acid 1.8520558911
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 9.5312819281 16049721
MESH:D009784 Occupational Diseases 4,4'-diaminodiphenylmethane 9.536482804 4026338
MESH:D009902 Optic Neuritis 4,4'-diaminodiphenylmethane 5.343988306
MESH:D010146 Pain Acetaminophen 2.5616870215
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 5.8616540662
MESH:D010190 Pancreatic Neoplasms gemcitabine 5.8611504793 18383843 16929163 17440100 18992248
MESH:D010212 Papilloma 4,4'-diaminodiphenylmethane 3.747296757
MESH:D010787 Photosensitivity Disorders 4,4'-diaminodiphenylmethane 4.796228378
MESH:D011230 Precancerous Conditions Diethylnitrosamine 3.732563599
MESH:D015427 Reperfusion Injury pirinixic acid 2.4719058328
MESH:D012162 Retinal Degeneration 4,4'-diaminodiphenylmethane 3.523692021
MESH:D012206 Rhabdomyolysis Lamivudine 5.829296927
MESH:D012640 Seizures 2,4-dinitrotoluene 2.6618551238
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 2.7118456281
MESH:D013274 Stomach Neoplasms Zidovudine 2.7117696246
MESH:D013964 Thyroid Neoplasms 4,4'-diaminodiphenylmethane 7.643712494 6587162 1399818 6582329 7505956
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 7.647505956
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 5.2416049721
MESH:D001749 Urinary Bladder Neoplasms 4,4'-diaminodiphenylmethane 5.248074119
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 4.6010091137
MESH:D014581 Urticaria Acetaminophen 3.2010982225
MESH:D014625 Vaginal Neoplasms Zidovudine 5.0212579204
No data
Pharmacogenomics Knowledge Base Top
Drug Bank Top
Drugbank ID Action Drug Name Description
DB00583 - L-Carnitine Vitamins (Vitamin B Complex);Nootropic Agents;Metabolite;Nutraceutical;Vitamin B Complex
No data
No data
No data

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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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