AutismKB 2.0

Annotation Detail for CCR3


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Basic Information Top
Gene Symbol:CCR3 ( CC-CKR-3,CD193,CKR3,CMKBR3,MGC102841 )
Gene Full Name: chemokine (C-C motif) receptor 3
Band: 3p21.31
Quick LinksEntrez ID:1232; OMIM: 601268; Uniprot ID:CCR3_HUMAN; ENSEMBL ID: ENSG00000183625; HGNC ID: 1604
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa04062Chemokine signaling pathway
hsa04060Cytokine-cytokine receptor interaction
Pathway IDPathway Name
Signaling by GPCR
No data
Pathway IDPathway Name
P00031Inflammation mediated by chemokine and cytokine signaling pathway
No data
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1934Cancer
2005Bronchial disease
2220Dermatitis
Desease Name
Celiac Disease
Asthma
IMMUNE
No data
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C103303 alitretinoin alitretinoin results in increased expression of CCR3 mRNAincreases expression 16712875
D000643 Ammonium Chloride Ammonium Chloride affects the expression of CCR3 mRNAaffects expression 16483693
C118980 antileukinate antileukinate inhibits the reaction [CCL11 protein binds to CCR3 protein]affects binding|decreases reaction 12842759
C118980 antileukinate antileukinate inhibits the reaction [CCL11 protein binds to CCR3 protein]affects binding|decreases reaction 12842759
D001241 Aspirin CCR3 gene SNP affects the susceptibility to Aspirinaffects response to substance 20485159
D001761 Bleomycin Bleomycin results in increased expression of CCR3 mRNAincreases expression 16314464
D001761 Bleomycin Bleomycin results in increased expression of CCR3 proteinincreases expression 16314464
D003907 Dexamethasone Dexamethasone results in decreased expression of CCR3 proteindecreases expression 15931867
D004997 Ethinyl Estradiol Ethinyl Estradiol results in decreased expression of CCR3 mRNAdecreases expression 15885639
12538720
D007213 Indomethacin Indomethacin results in decreased expression of CCR3 proteindecreases expression 11980903
D010126 Ozone Ozone results in increased expression of CCR3 proteinincreases expression 11777981
C043103 phthalic anhydride phthalic anhydride results in increased expression of CCR3 mRNAincreases expression 20219652
D010936 Plant Extracts Plant Extracts results in decreased expression of CCR3 mRNAdecreases expression 12462994
D010936 Plant Extracts Plant Extracts results in decreased expression of CCR3 proteindecreases expression 12462994
C013221 proanthocyanidin proanthocyanidin results in decreased expression of CCR3 mRNAdecreases expression 12462994
C013221 proanthocyanidin proanthocyanidin results in decreased expression of CCR3 proteindecreases expression 12462994
D016559 Tacrolimus Tacrolimus results in decreased expression of CCR3 mRNAdecreases expression 15948978
D014212 Tretinoin Tretinoin results in increased expression of CCR3 mRNAincreases expression 19828696
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000138 Acidosis Ammonium Chloride 3.6418287403
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 4.0417505938
MESH:D055371 Acute Lung Injury Bleomycin 4.9417118201
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 4.5114692618
MESH:D000230 Adenocarcinoma Indomethacin 4.5116537180
MESH:D000236 Adenoma Indomethacin 3.4811497255
MESH:D000505 Alopecia Tretinoin 3.6615955085
MESH:D016301 Alveolar Bone Loss Indomethacin 5.4717225004
MESH:D000544 Alzheimer Disease Indomethacin 6.8817627676 15579461
MESH:D000544 Alzheimer Disease Ozone 6.8815513908
MESH:D000544 Alzheimer Disease Plant Extracts 6.8816962711
MESH:D000860 Anoxia Bleomycin 5.4915782499
MESH:D001014 Aortic Aneurysm Indomethacin 4.9110231640
MESH:D017544 Aortic Aneurysm, Abdominal Indomethacin 4.9410388637
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.5411256880
MESH:D018771 Arthralgia Indomethacin 5.272160914
MESH:D001169 Arthritis, Experimental Dexamethasone 17.8417659584
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 17.8415885639
MESH:D001169 Arthritis, Experimental Plant Extracts 17.8414686799
MESH:D001169 Arthritis, Experimental Tretinoin 17.8416412693
MESH:D001172 Arthritis, Rheumatoid Indomethacin 7.5511248219
MESH:D001172 Arthritis, Rheumatoid Ozone 7.5515570426
MESH:D001172 Arthritis, Rheumatoid Tretinoin 7.5516292516
MESH:D001249 Asthma Ozone 8.2816373670 17854713
MESH:D001249 Asthma phthalic anhydride 8.283681491
MESH:D001249 Asthma Tretinoin 8.2816456186
MESH:D055963 Asthma, Aspirin-Induced marker/mechanism 20485159
MESH:D055963 Asthma, Aspirin-Induced Aspirin 4.7420485159 12372130
MESH:D001471 Barrett Esophagus Tretinoin 4.4716935849
MESH:D001477 Bartter Syndrome Indomethacin 5.0610684365
MESH:D001778 Blood Coagulation Disorders Tretinoin 3.6616206674 16197459
MESH:D001929 Brain Edema Indomethacin 5.1211481608
MESH:D002545 Brain Ischemia Indomethacin 10.8012524144
MESH:D002545 Brain Ischemia Plant Extracts 10.8016041641
MESH:D001932 Brain Neoplasms Aspirin 4.4715481559
MESH:D001943 Breast Neoplasms alitretinoin 2.0916344269
MESH:D001943 Breast Neoplasms Aspirin 2.0915161893
MESH:D001943 Breast Neoplasms Indomethacin 2.0917401462
MESH:D001943 Breast Neoplasms Tretinoin 2.0916873071 16443354 16166294
MESH:D016535 Bronchial Hyperreactivity Ozone 3.7217626835 15516495 18417511 18315731 16777450 14754758 19059883
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 4.6716813970
MESH:D002056 Burns Indomethacin 4.7810459503
MESH:D002057 Burns, Chemical Plant Extracts 5.439625245
MESH:D002100 Cachexia Indomethacin 12.6815625704 16537180 15141370 11239499
MESH:D002100 Cachexia Ozone 12.6816183385
MESH:D018236 Carcinoma, Embryonal Tretinoin 5.2616168501
MESH:D006528 Carcinoma, Hepatocellular Indomethacin 4.8516391822
MESH:D006528 Carcinoma, Hepatocellular Plant Extracts 4.8518834353
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 4.851917145
MESH:D018827 Carcinoma, Lewis Lung Indomethacin 4.8111053908
MESH:D018276 Carcinoma, Medullary Indomethacin 5.4314736730 11352223 18791128
MESH:D002292 Carcinoma, Renal Cell Indomethacin 3.4017341418
MESH:D002294 Carcinoma, Squamous Cell Bleomycin 7.876189445
MESH:D002294 Carcinoma, Squamous Cell Indomethacin 7.8715482327 12636206
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 7.8716051514 16096774
MESH:D006332 Cardiomegaly Plant Extracts 3.8317645561
MESH:D002318 Cardiovascular Diseases Tacrolimus 4.6517703430
MESH:D002386 Cataract Tretinoin 3.1217460283
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 4.6716129372
MESH:D002764 Cholecystitis Indomethacin 5.2711181007
MESH:D002779 Cholestasis Ethinyl Estradiol 2.9117110522 16919318 15861022 11677210 17333356 17681005 16105132
MESH:D002822 Choriocarcinoma Tretinoin 5.2616461808
MESH:D002972 Cleft Palate Tretinoin 2.699407595
MESH:D003092 Colitis Tretinoin 3.7817035595
MESH:D003110 Colonic Neoplasms Aspirin 6.1112411196
MESH:D003110 Colonic Neoplasms Dexamethasone 6.1115824018
MESH:D003110 Colonic Neoplasms Indomethacin 6.1111260862 15625704 15637740 15963497 15786552 15936596
MESH:D015179 Colorectal Neoplasms Aspirin 3.0217047198
MESH:D015179 Colorectal Neoplasms Indomethacin 3.0212606626 18059344 11197048 17054584
MESH:D018352 Coronavirus Infections Indomethacin 5.8117302372
MESH:D019465 Craniofacial Abnormalities Dexamethasone 2.8417728286
MESH:D019465 Craniofacial Abnormalities Tretinoin 2.849211117 9224671 9142499 16925845 8800419 17551590 9125849 14991402 10589399 9664655
MESH:D017449 Dermatitis, Allergic Contact Dexamethasone 3.4812438553
MESH:D003876 Dermatitis, Atopic marker/mechanism 18249437
MESH:D003928 Diabetic Nephropathies Plant Extracts 4.4519706694
MESH:D003967 Diarrhea Dexamethasone 8.497237001
MESH:D003967 Diarrhea Indomethacin 8.497237001 7907874
MESH:D004374 Ductus Arteriosus, Patent Indomethacin 5.2317190690 18446180 16326151 16133044 18043480 12774134
MESH:D004381 Duodenal Ulcer Indomethacin 10.0416699067 17045617 17202747 11535926 17351913 17151854 11595431 17329845 11991626 11595415 10671773
MESH:D004381 Duodenal Ulcer Tacrolimus 10.0417202747
MESH:D004485 Eczema Dexamethasone 4.5212438553
MESH:D004487 Edema Aspirin 22.3617259670
MESH:D004487 Edema Bleomycin 22.3617118201
MESH:D004487 Edema Dexamethasone 22.3619703484
MESH:D004487 Edema Indomethacin 22.368985016 7907874 10653021 16100529 8273558 19703484 7990266
MESH:D004487 Edema Plant Extracts 22.3612787963
MESH:D004489 Edema, Cardiac Tretinoin 4.5618230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 3.2512538720
MESH:D016889 Endometrial Neoplasms Tretinoin 3.1416569247
MESH:D004715 Endometriosis Indomethacin 4.2015652904
MESH:D004719 Endomyocardial Fibrosis Plant Extracts 5.7815268973
MESH:D019446 Endotoxemia Indomethacin 4.5818509659
MESH:D004751 Enteritis Indomethacin 4.8410567023 16328016 17763956
MESH:D020345 Enterocolitis, Necrotizing Indomethacin 5.0617980183
MESH:D004802 Eosinophilia Indomethacin 4.1211298111
MESH:D004827 Epilepsy Plant Extracts 3.7519439326 19700373
MESH:D004938 Esophageal Neoplasms Indomethacin 2.8211005569
MESH:D005124 Eye Abnormalities Tretinoin 3.629664655 16938888
MESH:D005234 Fatty Liver Ethinyl Estradiol 8.2215345470
MESH:D005234 Fatty Liver Plant Extracts 8.2215975614
MESH:D005334 Fever Indomethacin 4.1710431976 17627676 11852909
MESH:D005354 Fibrosarcoma Indomethacin 4.9810962813
MESH:D005355 Fibrosis Indomethacin 9.2717994277
MESH:D005355 Fibrosis Tretinoin 9.2717994277
MESH:D005499 Folliculitis Indomethacin 5.2711298111
MESH:D005756 Gastritis Indomethacin 4.8415046732
MESH:D005909 Glioblastoma Aspirin 12.2612870263
MESH:D005909 Glioblastoma Indomethacin 12.2612870263
MESH:D005909 Glioblastoma Tretinoin 12.2617312396
MESH:D005910 Glioma Indomethacin 3.2418371953 16487511
MESH:D005923 Glomerulosclerosis, Focal Segmental Indomethacin 4.3311849393
MESH:D006073 Gout Indomethacin 5.4311248219
MESH:D006086 Graft vs Host Disease Tacrolimus 5.9516376943
MESH:D006130 Growth Disorders Tacrolimus 4.9511041285
MESH:D006261 Headache Aspirin 5.0615240983
MESH:D006258 Head and Neck Neoplasms Indomethacin 8.0415482327
MESH:D006258 Head and Neck Neoplasms Tretinoin 8.0416096774
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 5.2616084493
MESH:D006330 Heart Defects, Congenital Tretinoin 2.9214991402 9664655
MESH:D006333 Heart Failure Plant Extracts 3.9018097624
MESH:D006501 Hepatic Encephalopathy Indomethacin 4.6215633222
MESH:D019698 Hepatitis C, Chronic Indomethacin 4.7515135802
MESH:D006548 Hernia, Diaphragmatic Dexamethasone 3.097520565
MESH:D006561 Herpes Simplex Plant Extracts 4.7110715843
MESH:D015658 HIV Infections marker/mechanism 10202824
MESH:D015658 HIV Infections Plant Extracts 3.7112878215
MESH:D006689 Hodgkin Disease Bleomycin 4.4217606976 15147373 18501091
MESH:D019584 Hot Flashes Plant Extracts 4.8417454163 16566672 14716179
MESH:D012001 Hyperacusis Aspirin 5.8615240983
MESH:D006930 Hyperalgesia Indomethacin 8.1612727271
MESH:D006930 Hyperalgesia Tretinoin 8.1616870215
MESH:D034321 Hyperamylasemia Indomethacin 5.8117883296
MESH:D006940 Hyperemia Indomethacin 5.0912524144
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 4.6416778211
MESH:D020138 Hyperhomocysteinemia Plant Extracts 4.5116484555
MESH:D006949 Hyperlipidemias Indomethacin 9.8517546600
MESH:D006949 Hyperlipidemias Plant Extracts 9.8515268973 15975614
MESH:D006967 Hypersensitivity phthalic anhydride 5.577930309
MESH:D006973 Hypertension Dexamethasone 2.9517042910
MESH:C537153 Hypomagnesemia primary Tacrolimus 6.2411041285
MESH:D007021 Hypospadias Ethinyl Estradiol 3.8816569931 16945680
MESH:D007022 Hypotension Tacrolimus 5.1811041285
MESH:D007077 Ileal Diseases Indomethacin 5.1218306037 10574470
MESH:D007079 Ileitis Indomethacin 5.4310651667 10647630 16133968
MESH:D007235 Infant, Premature, Diseases Indomethacin 5.4716133044
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.5212013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 2.5217937319
MESH:D007249 Inflammation Bleomycin 12.3717118201
MESH:D007249 Inflammation Dexamethasone 12.378960868 11099482
MESH:D007249 Inflammation Indomethacin 12.3712568917 3291741 7812673
MESH:D007249 Inflammation Plant Extracts 12.3712787963 19332304 15997105 16366677
MESH:D007410 Intestinal Diseases Indomethacin 10.1311855677 15831440 11686837 11713966 17994277 17329856 18236018 10210152 15610444
MESH:D007410 Intestinal Diseases Tretinoin 10.1317994277
MESH:D007414 Intestinal Neoplasms Plant Extracts 4.6712628509 12584176 12351151
MESH:D019586 Intracranial Hypertension Indomethacin 5.4715241188
MESH:D007569 Jaw Abnormalities Tretinoin 3.9515992940 17551590
MESH:D007579 Jejunal Diseases Indomethacin 5.1210574470 16133968 18306037
MESH:D017492 Keratosis, Seborrheic alitretinoin 5.7216144296
MESH:D007674 Kidney Diseases Indomethacin 7.0017190690
MESH:D007674 Kidney Diseases Tacrolimus 7.0011041285
MESH:D016773 Leishmaniasis, Cutaneous Indomethacin 3.9512228301 11703811 10320625
MESH:D007938 Leukemia Tretinoin 2.7917143497
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive Indomethacin 3.9616572323 10785260 15631656
MESH:D007951 Leukemia, Myeloid Tretinoin 3.7519285840 16932348 16482212
MESH:D015470 Leukemia, Myeloid, Acute Indomethacin 4.0918360721
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 4.0917596541 19850784 16294345
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 3.1916891316 17506722 9834237 16823087 17712046 12679006 17649720 16788101 19075265 17294898 17361223 16140955 17301526 17107899 17368321 17217047 19225113 16331271 19035177 17339181 16935935 19029980 15748426 19642359 16766008
MESH:D007964 Leukocytosis Indomethacin 5.4716537180
MESH:D007969 Leukomalacia, Periventricular Indomethacin 5.8117980183
MESH:D017880 Limb Deformities, Congenital Tretinoin 3.349224671
MESH:D008101 Liver Abscess, Amebic Indomethacin 5.8111479899
MESH:D008103 Liver Cirrhosis Plant Extracts 3.7617157831
MESH:D008106 Liver Cirrhosis, Experimental Dexamethasone 5.1216718785
MESH:D008106 Liver Cirrhosis, Experimental Indomethacin 5.1218194892
MESH:D008106 Liver Cirrhosis, Experimental Plant Extracts 5.1215479170
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 5.1218397230 16248980
MESH:D008107 Liver Diseases Plant Extracts 3.0217034775
MESH:D008113 Liver Neoplasms Plant Extracts 3.1719168119
MESH:D008171 Lung Diseases Ozone 3.4119066396 8266340
MESH:D055370 Lung Injury Ozone 3.9220417186
MESH:D008175 Lung Neoplasms alitretinoin 8.6716413115
MESH:D008175 Lung Neoplasms Bleomycin 8.676189445
MESH:D008175 Lung Neoplasms Dexamethasone 8.6711195469 15824018
MESH:D008175 Lung Neoplasms Indomethacin 8.6716537180 11053908 11497255
MESH:D008175 Lung Neoplasms Ozone 8.677614698 8597069
MESH:D008175 Lung Neoplasms Plant Extracts 8.6720869020
MESH:D008527 Medulloblastoma Tretinoin 2.8017453147
MESH:D008545 Melanoma Bleomycin 3.8215577320
MESH:D008545 Melanoma Tretinoin 3.8216752155
MESH:D008591 Meningomyelocele Tretinoin 4.5016940565
MESH:D008679 Metaplasia Ozone 5.2010496685
MESH:D008881 Migraine Disorders Aspirin 8.1715240983
MESH:D008881 Migraine Disorders Indomethacin 8.1711903285
MESH:D009062 Mouth Neoplasms Indomethacin 4.0312636206
MESH:D009101 Multiple Myeloma Dexamethasone 3.5415744524 15867202 16118317
MESH:D009190 Myelodysplastic Syndromes Dexamethasone 7.649809623
MESH:D009190 Myelodysplastic Syndromes Tretinoin 7.6417596541
MESH:D009203 Myocardial Infarction Aspirin 3.5712692751
MESH:D009325 Nausea Aspirin 5.3115240983
MESH:D009362 Neoplasm Metastasis Indomethacin 3.1916537180 11239499 11053908
MESH:D009369 Neoplasms alitretinoin 5.4716946489
MESH:D009369 Neoplasms Tretinoin 5.4716594593 16946489
MESH:D009374 Neoplasms, Experimental Indomethacin 4.2110663608 15625704
MESH:D009421 Nervous System Malformations Tretinoin 3.849125849
MESH:D009436 Neural Tube Defects Tretinoin 3.099142499
MESH:D019954 Neurobehavioral Manifestations Plant Extracts 5.2517168769
MESH:D019636 Neurodegenerative Diseases Indomethacin 9.3212349958
MESH:D019636 Neurodegenerative Diseases Tacrolimus 9.3215081597
MESH:D009765 Obesity Plant Extracts 3.1520132043 19056576
MESH:D007752 Obstetric Labor, Premature Indomethacin 5.276374098
MESH:D010003 Osteoarthritis Aspirin 8.127009135
MESH:D010003 Osteoarthritis Indomethacin 8.127009135
MESH:D010051 Ovarian Neoplasms Tretinoin 2.3616936753
MESH:D010146 Pain Aspirin 11.746363464 6995502
MESH:D010146 Pain Indomethacin 11.7417627676 13679232 17440234 3291741
MESH:D010146 Pain Tretinoin 11.7416870215
MESH:D010149 Pain, Postoperative Indomethacin 4.7812538197 18702446
MESH:D010190 Pancreatic Neoplasms Tretinoin 2.4815976015
MESH:D010195 Pancreatitis Indomethacin 3.9817883296 15028970
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.7511578682
MESH:D010212 Papilloma Plant Extracts 4.5615173996 16517061
MESH:D010257 Paraneoplastic Syndromes Indomethacin 5.8116537180
MESH:D020734 Parkinsonian Disorders Indomethacin 4.1712349958
MESH:D051302 Paroxysmal Hemicrania Indomethacin 5.8111903285
MESH:D010437 Peptic Ulcer Indomethacin 5.2311148446
MESH:D010438 Peptic Ulcer Hemorrhage Aspirin 5.6211156591
MESH:D010518 Periodontitis Indomethacin 5.0117225004
MESH:D010538 Peritonitis Ozone 4.2016369182
MESH:D020795 Photophobia Aspirin 5.8615240983
MESH:D011014 Pneumonia Bleomycin 11.7016317386 17071938 18024389
MESH:D011014 Pneumonia Ozone 11.7018007984 18381685 18929643
MESH:D017499 Porokeratosis alitretinoin 6.1016144296
MESH:D054198 Precursor Cell Lymphoblastic Leukemia-Lymphoma Dexamethasone 3.5721297632
MESH:D047928 Premature Birth Indomethacin 5.2017000239
MESH:D011471 Prostatic Neoplasms Plant Extracts 4.0714666653 17804756
MESH:D011507 Proteinuria Indomethacin 9.5311849393
MESH:D011507 Proteinuria Tretinoin 9.5316636307
MESH:D011537 Pruritus Ethinyl Estradiol 3.3915861022 16919318
MESH:D011625 Pterygium Tretinoin 4.8816723453
MESH:D011654 Pulmonary Edema Bleomycin 5.4115808516
MESH:D011658 Pulmonary Fibrosis marker/mechanism 16314464
MESH:D011658 Pulmonary Fibrosis Bleomycin 3.8816314464 17241526 21435439 14609568 16115399 11554783 15322207 12624602 18162602 15541506 17177178 12574379 18008008 17434272
MESH:D012128 Respiratory Distress Syndrome, Adult Dexamethasone 4.0718379247 11700416
MESH:D012130 Respiratory Hypersensitivity phthalic anhydride 5.3920219652
MESH:D012208 Rhabdomyosarcoma Tretinoin 4.1616283617 16116481
MESH:D012220 Rhinitis Aspirin 9.8112372130
MESH:D012220 Rhinitis phthalic anhydride 9.813681491
MESH:D012851 Sinus Thrombosis, Intracranial Aspirin 5.3412269725
MESH:D012878 Skin Neoplasms Plant Extracts 6.1716517061 15173996
MESH:D012878 Skin Neoplasms Tretinoin 6.1716467112
MESH:D013088 Spermatocele Ethinyl Estradiol 4.0416709447
MESH:D013272 Stomach Diseases Dexamethasone 10.6515472012
MESH:D013272 Stomach Diseases Indomethacin 10.6516184426 10486359 17638125 10215738 15038085 15472012 18545984 17160473 16113693 17207306 16280098 10192188 18209964
MESH:D013274 Stomach Neoplasms Indomethacin 2.6515609394
MESH:D013274 Stomach Neoplasms Tretinoin 2.6517261132
MESH:D013276 Stomach Ulcer Dexamethasone 12.5715138204
MESH:D013276 Stomach Ulcer Indomethacin 12.5717918041 1323529 18193104 17135157 16631530 16755016 11906479 15104355 17657623 18237397 17895592 17627676 16169175 15138204 17977527 11523592 16934674 16397915 11595431 11145282 11595415 15255614 18087811 10750652 12787963 12077510 18299717 10878458 11729361 18543354 18181030 16150113 17654042 18431645 18726076 12500499 14567935 16252198 12467913 10423059 18209962 12498302
MESH:D013276 Stomach Ulcer Plant Extracts 12.5715255614 18193104 17135157 18237397 12787963
MESH:D020521 Stroke Aspirin 4.4216403987
MESH:D013705 Temporomandibular Joint Disorders Plant Extracts 5.5817997062
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.6811994571
MESH:D013927 Thrombosis Aspirin 9.3617672075
MESH:D013927 Thrombosis Ethinyl Estradiol 9.3615669648
MESH:D013964 Thyroid Neoplasms Indomethacin 7.5318791128 11352223 14736730
MESH:D013964 Thyroid Neoplasms Tretinoin 7.5316026305 17045167
MESH:D014062 Tongue Neoplasms Tretinoin 3.8416051514
MESH:D014376 Tuberculosis Tretinoin 3.2616040207
MESH:D014456 Ulcer Indomethacin 4.9817380554 10574470
MESH:D014581 Urticaria Aspirin 4.5020485159 10982225
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 3.7316129372
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.3614692618
MESH:D014604 Uveal Neoplasms Tretinoin 4.7116752155
MESH:D014605 Uveitis Dexamethasone 4.911336536
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.5915869587 14671159
MESH:D018487 Ventricular Dysfunction, Left Plant Extracts 4.8218097624
MESH:D020257 Ventricular Remodeling Plant Extracts 5.4018097624
MESH:D014820 Vitiligo Tretinoin 4.1216761959
MESH:D014839 Vomiting Indomethacin 4.8411897121
MESH:D015431 Weight Loss Bleomycin 5.7212624602
MESH:D009396 Wilms Tumor Tretinoin 4.0216287080
MESH:D014947 Wounds and Injuries Plant Extracts 4.3020213670 19894650
Pathway ID Pathway Name
KEGG:04062 Chemokine signaling pathway
KEGG:04060 Cytokine-cytokine receptor interaction
REACT:14797 Signaling by GPCR
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA26168
  • No data
    No data
    Releated drug ID Related drug Name
    PA164744376adenosine monophosphate
    PA449773glucose
    PA448478l-arginine
    PA164747225l-citrulline
    PA450635nitric oxide
    PA164743471adenosine triphosphate
    Drug Bank Top

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018