AutismKB 2.0

Annotation Detail for TARSL2


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Basic Information Top
Gene Symbol:TARSL2 ( FLJ25005 )
Gene Full Name: threonyl-tRNA synthetase-like 2
Band: 15q26.3
Quick LinksEntrez ID:123283; OMIM: NA; Uniprot ID:SYTC2_HUMAN; ENSEMBL ID: ENSG00000185418; HGNC ID: 24728
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Pathway IDPathway Name
TRNA-CHARGING-PWYtRNA charging pathway
Pathway IDPathway Name
hsa00970Aminoacyl-tRNA biosynthesis
No data
No data
No data
No data
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000082 Acetaminophen Acetaminophen affects the expression of TARSL2 mRNAaffects expression 17562736
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000799 Angioedema Acetaminophen 5.2610982225
MESH:D001321 Autistic Disorder Acetaminophen 1.3918445737
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 1.413084413
MESH:D002386 Cataract Acetaminophen 2.8610977129
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 1.6914550746 10663392 16485898 19739265 19923254 19085960 10774834 12153990 19164858 16109766 17522070 16781746 15619225 10915739 12594235 14725611 16393943 11834606 15968718 16227642 19420014 12958197 2444490 12705907 12392966 16081117 17562736 16177239 19370779 11461765 11421492 14986274 11529661 11739529 11287661 17906064 18713872 19416960 11743745 12540782 18071297
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 5.5119426721
MESH:D005756 Gastritis Acetaminophen 5.0916983495
MESH:D006930 Hyperalgesia Acetaminophen 3.1516870215
MESH:D007674 Kidney Diseases Acetaminophen 2.4715629191 12587719
MESH:D008107 Liver Diseases Acetaminophen 1.7212969438 16611625 12587719 19460945 11587558 19784758 19014921 16610002
MESH:D017114 Liver Failure, Acute Acetaminophen 3.8116871587 17185352
MESH:D008546 Melanoma, Experimental Acetaminophen 4.4719513568
MESH:D019636 Neurodegenerative Diseases Acetaminophen 3.3618514411
MESH:D010146 Pain Acetaminophen 2.8716870215
MESH:D014581 Urticaria Acetaminophen 3.6710982225
Pathway ID Pathway Name
KEGG:00970 Aminoacyl-tRNA biosynthesis
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA128394753
  • No data
    Releated disease ID Related disease Name
    PA446155Precursor Cell Lymphoblastic Leukemia-Lymphoma
    No data
    Drug Bank Top

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    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018