AutismKB 2.0

Annotation Detail for SPACA3


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Basic Information Top
Gene Symbol:SPACA3 ( 1700025M08Rik,ALLP17,CT54,LYC3,LYZL3,MGC119058,SLLP1 )
Gene Full Name: sperm acrosome associated 3
Band: 17q11.2
Quick LinksEntrez ID:124912; OMIM: 612749; Uniprot ID:SACA3_HUMAN; ENSEMBL ID: ENSG00000141316; HGNC ID: 16260
Relate to Another Database: SFARIGene; denovo-db
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Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000082 Acetaminophen Acetaminophen affects the expression of SPACA3 mRNAaffects expression 17562736
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000799 Angioedema Acetaminophen 5.2610982225
MESH:D001321 Autistic Disorder Acetaminophen 1.3918445737
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 1.413084413
MESH:D002386 Cataract Acetaminophen 2.8610977129
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 1.6914725611 10663392 10915739 10774834 19739265 14986274 12705907 19370779 16177239 11421492 11743745 17522070 11287661 16081117 18071297 17562736 16781746 16227642 19416960 11834606 15968718 2444490 19085960 18713872 11739529 16485898 11461765 12594235 17906064 12958197 12540782 19923254 14550746 16109766 16393943 11529661 12392966 15619225 19164858 12153990 19420014
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 5.5119426721
MESH:D005756 Gastritis Acetaminophen 5.0916983495
MESH:D006930 Hyperalgesia Acetaminophen 3.1516870215
MESH:D007674 Kidney Diseases Acetaminophen 2.4715629191 12587719
MESH:D008107 Liver Diseases Acetaminophen 1.7219460945 16611625 19014921 11587558 19784758 12969438 16610002 12587719
MESH:D017114 Liver Failure, Acute Acetaminophen 3.8117185352 16871587
MESH:D008546 Melanoma, Experimental Acetaminophen 4.4719513568
MESH:D019636 Neurodegenerative Diseases Acetaminophen 3.3618514411
MESH:D010146 Pain Acetaminophen 2.8716870215
MESH:D014581 Urticaria Acetaminophen 3.6710982225
No data
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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018