Annotation Detail for GGT6
Basic Information Top
| Gene Symbol: | GGT6 ( FLJ25990,FLJ90165 ) |
|---|---|
| Gene Full Name: | gamma-glutamyltransferase 6 |
| Band: | 17p13.2 |
| Quick Links | Entrez ID:124975; OMIM: 612341; Uniprot ID:GGT6_HUMAN; ENSEMBL ID: ENSG00000167741; HGNC ID: 26891 |
| Relate to Another Database: | SFARIGene; denovo-db |
| Pathway ID | Pathway Name |
|---|---|
| PWY-4041 | gamma-glutamyl cycle |
| Pathway ID | Pathway Name |
|---|---|
| hsa00480 | Glutathione metabolism |
| hsa00590 | Arachidonic acid metabolism |
| hsa00430 | Taurine and hypotaurine metabolism |
| hsa00450 | Selenoamino acid metabolism |
| hsa01100 | Metabolic pathways |
| hsa00460 | Cyanoamino acid metabolism |
| No data |
| No data |
| No data |
| No data |
Related Diseases/Disorders| Chemical ID | Chemical Name | Interaction | Interaction Action | Publication |
|---|---|---|---|---|
| D000082 | Acetaminophen | Acetaminophen affects the expression of GGT6 mRNA | affects expression | 17562736 |
| Disease ID | Disease Name | Direct Evidence | Inference Chemical Name | Inference Score | Publication |
|---|---|---|---|---|---|
| MESH:D000799 | Angioedema | Acetaminophen | 5.26 | 10982225 | |
| MESH:D001321 | Autistic Disorder | Acetaminophen | 1.39 | 18445737 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Acetaminophen | 1.41 | 3084413 | |
| MESH:D002386 | Cataract | Acetaminophen | 2.86 | 10977129 | |
| MESH:D056486 | Drug-Induced Liver Injury | Acetaminophen | 1.69 | 16177239 16485898 12540782 11739529 10915739 11743745 12958197 18713872 12705907 11529661 12153990 19420014 18071297 16393943 14986274 19164858 11287661 10663392 19416960 12594235 16081117 17562736 15968718 14550746 17906064 19370779 19739265 2444490 16781746 19923254 16227642 15619225 14725611 10774834 11834606 12392966 19085960 16109766 11421492 17522070 11461765 | |
| MESH:D056487 | Drug-Induced Liver Injury, Chronic | Acetaminophen | 5.51 | 19426721 | |
| MESH:D005756 | Gastritis | Acetaminophen | 5.09 | 16983495 | |
| MESH:D006930 | Hyperalgesia | Acetaminophen | 3.15 | 16870215 | |
| MESH:D007674 | Kidney Diseases | Acetaminophen | 2.47 | 12587719 15629191 | |
| MESH:D008107 | Liver Diseases | Acetaminophen | 1.72 | 19014921 16610002 19460945 16611625 12969438 11587558 19784758 12587719 | |
| MESH:D017114 | Liver Failure, Acute | Acetaminophen | 3.81 | 17185352 16871587 | |
| MESH:D008546 | Melanoma, Experimental | Acetaminophen | 4.47 | 19513568 | |
| MESH:D019636 | Neurodegenerative Diseases | Acetaminophen | 3.36 | 18514411 | |
| MESH:D010146 | Pain | Acetaminophen | 2.87 | 16870215 | |
| MESH:D014581 | Urticaria | Acetaminophen | 3.67 | 10982225 |
| Pathway ID | Pathway Name |
|---|---|
| KEGG:00590 | Arachidonic acid metabolism |
| KEGG:00460 | Cyanoamino acid metabolism |
| KEGG:00480 | Glutathione metabolism |
| KEGG:01100 | Metabolic pathways |
| KEGG:00430 | Taurine and hypotaurine metabolism |