AutismKB 2.0

Annotation Detail for TTC39C


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Basic Information Top
Gene Symbol:TTC39C ( C18orf17,FLJ33761,FLJ90394,HsT2697 )
Gene Full Name: tetratricopeptide repeat domain 39C
Band: 18q11.2
Quick LinksEntrez ID:125488; OMIM: NA; Uniprot ID:TT39C_HUMAN; ENSEMBL ID: ENSG00000168234; HGNC ID: 26595
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000082 Acetaminophen Acetaminophen affects the expression of TTC39C mRNAaffects expression 17562736
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of TTC39C mRNAaffects expression 17555576
D010634 Phenobarbital NR1I3 protein affects the reaction [Phenobarbital results in decreased expression of TTC39C mRNA]affects reaction|decreases expression 19482888
D010634 Phenobarbital Phenobarbital results in decreased expression of TTC39C mRNAdecreases expression 19482888
D013629 Tamoxifen Tamoxifen affects the expression of TTC39C mRNAaffects expression 17555576
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 5.2714745880
MESH:D000014 Abnormalities, Drug-Induced Phenobarbital 4.076195326
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 4.6617505938
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 1.8814692618
MESH:D018248 Adenoma, Liver Cell Phenobarbital 4.6017620307
MESH:D000799 Angioedema Acetaminophen 4.5710982225
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 4.0211256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 2.8915885639
MESH:D001321 Autistic Disorder Acetaminophen 1.4018445737
MESH:D001943 Breast Neoplasms Tamoxifen 2.1718997820 19011961 19221464 19487384 16202921 20390343 20065188 19288272 18629630 21138602 18821012 19084267 19289846 21152245 19155303 19410462 15565566 17049068 20005174 20859285 15668708 17261762 19244106 17440819 17893378 19200415 18815881 16873071 19142967 17242785 16273361 19066611 20544844 18984771 18855134 11161223 18351453 19189210 19115204 16818667 19059307 18425577 19189212 19103187 20135344
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 5.0719066611
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 4.813084413
MESH:D006528 Carcinoma, Hepatocellular Phenobarbital 4.811701930 6705139 17173139 20007298 20935162
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 4.8116924424
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 4.0117572228
MESH:D002386 Cataract Acetaminophen 2.7910977129
MESH:D002493 Central Nervous System Diseases Phenobarbital 4.814080065
MESH:D002779 Cholestasis Ethinyl Estradiol 3.1716919318 11677210 17333356 16105132 15861022 17110522 17681005
MESH:D003711 Demyelinating Diseases Tamoxifen 4.9219031437
MESH:D003928 Diabetic Nephropathies Tamoxifen 3.8419279558
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 1.6719739265 17522070 11529661 16109766 12540782 11421492 10663392 19164858 11743745 14986274 14725611 12705907 18713872 19416960 12153990 11834606 16781746 19085960 11739529 16227642 14550746 10915739 18071297 11461765 19420014 17906064 16081117 15968718 19923254 12392966 16177239 19370779 17562736 11287661 12594235 12958197 16485898 10774834 16393943 15619225 2444490
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.8219426721
MESH:D004421 Dystonia Phenobarbital 4.471851702
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 10.6812538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 10.6819031437
MESH:D016889 Endometrial Neoplasms Tamoxifen 3.2919155303 20544844 16202921 17893378
MESH:D004831 Epilepsies, Myoclonic Phenobarbital 4.673659116
MESH:D004828 Epilepsies, Partial Phenobarbital 4.5911558140 3922381
MESH:D004827 Epilepsy Phenobarbital 3.0620417680
MESH:D004832 Epilepsy, Absence Phenobarbital 3.916401628
MESH:D017029 Epilepsy, Complex Partial Phenobarbital 4.817750514
MESH:D004830 Epilepsy, Tonic-Clonic Phenobarbital 4.653659116
MESH:D005234 Fatty Liver Ethinyl Estradiol 9.1415345470
MESH:D005234 Fatty Liver Tamoxifen 9.1414986274 19224547
MESH:D052776 Female Urogenital Diseases Tamoxifen 3.4516709447
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 5.1614745880
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 4.8119069698
MESH:D005756 Gastritis Acetaminophen 4.4016983495
MESH:D006529 Hepatomegaly Phenobarbital 4.0416109766
MESH:D006930 Hyperalgesia Acetaminophen 3.0216870215
MESH:D007021 Hypospadias Ethinyl Estradiol 4.3716945680 16569931
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.9212013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 2.7317937319
MESH:D007249 Inflammation Tamoxifen 2.5319457130
MESH:D007674 Kidney Diseases Acetaminophen 2.4015629191 12587719
MESH:D007680 Kidney Neoplasms Tamoxifen 3.3818625569
MESH:D008064 Lipidoses Tamoxifen 3.4317567588 15342952
MESH:D008103 Liver Cirrhosis Phenobarbital 3.0821047994
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 1.7518564211
MESH:D008107 Liver Diseases Acetaminophen 4.2019460945 12969438 12587719 19784758 11587558 16611625 16610002 19014921
MESH:D008107 Liver Diseases Phenobarbital 4.2019363144
MESH:D017114 Liver Failure, Acute Acetaminophen 3.6316871587 17185352
MESH:D008113 Liver Neoplasms Phenobarbital 5.0221047994 19812893 8742319 15975961 19073162 19482888
MESH:D008113 Liver Neoplasms Tamoxifen 5.0216684651
MESH:D008114 Liver Neoplasms, Experimental Phenobarbital 2.926150874 18308698 1399818 17172636 2563599
MESH:D008175 Lung Neoplasms Tamoxifen 1.7418625569
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 4.3919428831
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 2.8619196723 11731420 16827153 14580682 19196722
MESH:D020149 Manganese Poisoning Tamoxifen 5.2719453300
MESH:D008545 Melanoma Tamoxifen 1.9219393235 12393984
MESH:D018328 Melanoma, Amelanotic Tamoxifen 4.8115990972
MESH:D008546 Melanoma, Experimental Acetaminophen 4.1319513568
MESH:D020191 Myoclonic Epilepsies, Progressive Phenobarbital 5.1117484760
MESH:D009362 Neoplasm Metastasis Tamoxifen 2.6719393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.6119410462
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 4.7219196722 19189210 19200415
MESH:D019636 Neurodegenerative Diseases Acetaminophen 3.2118514411
MESH:D010018 Osteomalacia Phenobarbital 5.0017016548
MESH:D010146 Pain Acetaminophen 2.7316870215
MESH:D010190 Pancreatic Neoplasms Phenobarbital 2.6016965848
MESH:D016584 Panic Disorder Ethinyl Estradiol 4.1511578682
MESH:D011230 Precancerous Conditions Phenobarbital 3.992563599
MESH:D011471 Prostatic Neoplasms Tamoxifen 3.0915067354
MESH:D011537 Pruritus Ethinyl Estradiol 3.9415861022 16919318
MESH:D019310 Pseudolymphoma Phenobarbital 5.2212752131
MESH:D012640 Seizures Phenobarbital 2.954039156 3137016 16876388 11442880
MESH:D003294 Seizures, Febrile Phenobarbital 5.456407741
MESH:D013088 Spermatocele Ethinyl Estradiol 14.1116709447
MESH:D013088 Spermatocele Tamoxifen 14.1116709447
MESH:D013119 Spinal Cord Injuries Tamoxifen 4.6719457130
MESH:D019851 Thrombophilia Ethinyl Estradiol 4.0811994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.5215669648
MESH:D013964 Thyroid Neoplasms Phenobarbital 3.361399818
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 2.4817572228 8653321 16712894
MESH:D014581 Urticaria Acetaminophen 3.4410982225
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.8014692618
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.9715869587 14671159
No data
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Syndromic Genes

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AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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