Annotation Detail for ZNF440

 Basic Information 
Top
 
        	
        			| Chemical ID | 
					Chemical Name | 
					Interaction | 
					Interaction Action | 
					Publication | 
|---|
| D001564 | 
					Benzo(a)pyrene | 
					Benzo(a)pyrene results in increased expression of ZNF440 mRNA | increases expression  | 20106945
  | 
| D016572 | 
					Cyclosporine | 
					Cyclosporine results in decreased expression of ZNF440 mRNA | decreases expression  | 20106945
  | 
| Disease ID | 
					Disease Name | 
					Direct Evidence | 
					Inference Chemical Name | 
					Inference Score | 
					Publication | 
|---|
| MESH:D000230 | 
					Adenocarcinoma | 
					 | 
					Benzo(a)pyrene | 
					2.07 | 20464547	20127859	 | 
| MESH:D000236 | 
					Adenoma | 
					 | 
					Benzo(a)pyrene | 
					2.90 | 6695378	 | 
| MESH:D017544 | 
					Aortic Aneurysm, Abdominal | 
					 | 
					Benzo(a)pyrene | 
					4.84 | 19183758	 | 
| MESH:D001943 | 
					Breast Neoplasms | 
					 | 
					Benzo(a)pyrene | 
					1.98 | 20146248	17474063	 | 
| MESH:D002294 | 
					Carcinoma, Squamous Cell | 
					 | 
					Benzo(a)pyrene | 
					2.15 | 20419170	 | 
| MESH:D002471 | 
					Cell Transformation, Neoplastic | 
					 | 
					Cyclosporine | 
					2.85 | 12371664	 | 
| MESH:D002779 | 
					Cholestasis | 
					 | 
					Cyclosporine | 
					3.28 | 19486331	 | 
| MESH:D004938 | 
					Esophageal Neoplasms | 
					 | 
					Benzo(a)pyrene | 
					2.09 | 16530937	 | 
| MESH:D005234 | 
					Fatty Liver | 
					 | 
					Cyclosporine | 
					3.40 | 19224547	 | 
| MESH:D005355 | 
					Fibrosis | 
					 | 
					Cyclosporine | 
					3.90 | 12168785	12639820	 | 
| MESH:D005885 | 
					Gingival Hyperplasia | 
					 | 
					Cyclosporine | 
					5.11 | 8708960	 | 
| MESH:D006330 | 
					Heart Defects, Congenital | 
					 | 
					Benzo(a)pyrene | 
					2.87 | 20471113	 | 
| MESH:D006457 | 
					Hemoglobinuria, Paroxysmal | 
					 | 
					Cyclosporine | 
					5.31 | 15720958	 | 
| MESH:D006973 | 
					Hypertension | 
					 | 
					Cyclosporine | 
					2.24 | 10903974	 | 
| MESH:D007638 | 
					Keratoconjunctivitis Sicca | 
					 | 
					Cyclosporine | 
					5.51 | 15604871	 | 
| MESH:D007674 | 
					Kidney Diseases | 
					 | 
					Cyclosporine | 
					2.58 | 18776723	10903974	8314463	 | 
| MESH:D007680 | 
					Kidney Neoplasms | 
					 | 
					Cyclosporine | 
					3.17 | 12371664	 | 
| MESH:D008113 | 
					Liver Neoplasms | 
					 | 
					Benzo(a)pyrene | 
					2.18 | 20195826	21137059	 | 
| MESH:D008175 | 
					Lung Neoplasms | 
					 | 
					Benzo(a)pyrene | 
					1.57 | 20869020	18569708	6695378	18816296	20064080	20135361	18520028	17053015	20464547	 | 
| MESH:D008664 | 
					Metal Metabolism, Inborn Errors | 
					 | 
					Cyclosporine | 
					5.86 | 16801185	 | 
| MESH:D009062 | 
					Mouth Neoplasms | 
					 | 
					Benzo(a)pyrene | 
					3.57 | 16381670	 | 
| MESH:D009369 | 
					Neoplasms | 
					 | 
					Benzo(a)pyrene | 
					2.36 | 11141357	 | 
| MESH:D009402 | 
					Nephrosis, Lipoid | 
					 | 
					Cyclosporine | 
					5.51 | 17954296	 | 
| MESH:D009404 | 
					Nephrotic Syndrome | 
					 | 
					Cyclosporine | 
					3.75 | 19348381	18481113	 | 
| MESH:D011230 | 
					Precancerous Conditions | 
					 | 
					Cyclosporine | 
					3.69 | 12371664	 | 
| MESH:D011471 | 
					Prostatic Neoplasms | 
					 | 
					Benzo(a)pyrene | 
					2.90 | 17292933	 | 
| MESH:D011565 | 
					Psoriasis | 
					 | 
					Cyclosporine | 
					2.35 | 16882103	 | 
| MESH:D012878 | 
					Skin Neoplasms | 
					 | 
					Benzo(a)pyrene | 
					2.55 | 19755658	10029692	 | 
| MESH:D013274 | 
					Stomach Neoplasms | 
					 | 
					Benzo(a)pyrene | 
					1.56 | 20155912	2093021	 | 
| MESH:D001749 | 
					Urinary Bladder Neoplasms | 
					 | 
					Benzo(a)pyrene | 
					2.32 | 17053015	 | 
| MESH:D014605 | 
					Uveitis | 
					 | 
					Cyclosporine | 
					5.05 | 1336536	 | 
| MESH:D014985 | 
					Xerophthalmia | 
					 | 
					Cyclosporine | 
					5.51 | 17120751	 |