AutismKB 2.0

Annotation Detail for JSRP1


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Basic Information Top
Gene Symbol:JSRP1 ( FLJ32416,JP-45 )
Gene Full Name: junctional sarcoplasmic reticulum protein 1
Band: 19p13.3
Quick LinksEntrez ID:126306; OMIM: 608743; Uniprot ID:JSPR1_HUMAN; ENSEMBL ID: ENSG00000167476; HGNC ID: 24963
Relate to Another Database: SFARIGene; denovo-db
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Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D003474 Curcumin Curcumin results in decreased expression of JSRP1 mRNAdecreases expression 17198877
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D019973 Alcohol-Related Disorders Curcumin 6.5017887948
MESH:D000544 Alzheimer Disease Curcumin 2.7015590663
MESH:D001172 Arthritis, Rheumatoid Curcumin 2.8216807698
MESH:D050197 Atherosclerosis Curcumin 3.6018704882
MESH:D001327 Autoimmune Diseases Curcumin 5.4019761891
MESH:D002545 Brain Ischemia Curcumin 5.4216770732
MESH:D001932 Brain Neoplasms Curcumin 4.5117596214
MESH:D001943 Breast Neoplasms Curcumin 2.6916243823 19250217 18462866 18593918
MESH:D002277 Carcinoma Curcumin 4.2918593918
MESH:D002289 Carcinoma, Non-Small-Cell Lung Curcumin 3.1118414057
MESH:D002294 Carcinoma, Squamous Cell Curcumin 2.8718462866
MESH:D003092 Colitis Curcumin 5.0816804969 16782535 18200517
MESH:D003103 Coloboma Curcumin 5.1818809619
MESH:D003110 Colonic Neoplasms Curcumin 2.5616340194 19359593
MESH:D016510 Corneal Neovascularization Curcumin 5.8018497527
MESH:D003924 Diabetes Mellitus, Type 2 Curcumin 2.7918403477
MESH:D003928 Diabetic Nephropathies Curcumin 4.5418204486
MESH:D004381 Duodenal Ulcer Curcumin 4.8317351913
MESH:D005234 Fatty Liver Curcumin 4.3219297423
MESH:D005355 Fibrosis Curcumin 4.8918705752
MESH:D005770 Gastrointestinal Neoplasms Curcumin 5.6018462866
MESH:D005909 Glioblastoma Curcumin 3.8017596214
MESH:D006258 Head and Neck Neoplasms Curcumin 4.0018829502 18462866
MESH:D015417 Hereditary Sensory and Motor Neuropathy Curcumin 5.9517701891
MESH:D006937 Hypercholesterolemia Curcumin 4.6818704882
MESH:D007249 Inflammation Curcumin 3.1217151092 18403477 16956363
MESH:D015212 Inflammatory Bowel Diseases Curcumin 3.3718596194 18200517
MESH:D007414 Intestinal Neoplasms Curcumin 4.7910783313
MESH:D007889 Leiomyoma Curcumin 5.2718555241
MESH:D007938 Leukemia Curcumin 3.4618462866
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell Curcumin 4.8316106398
MESH:D015458 Leukemia, T-Cell Curcumin 5.5516106398
MESH:D008106 Liver Cirrhosis, Experimental Curcumin 2.2917355460 18705752 18006644
MESH:D008107 Liver Diseases Curcumin 2.7016956363
MESH:D008175 Lung Neoplasms Curcumin 2.2819359593 18462866 16243823
MESH:D008223 Lymphoma Curcumin 3.9618462866
MESH:D016399 Lymphoma, T-Cell Curcumin 5.6016173963
MESH:D008545 Melanoma Curcumin 2.4617885582 18462866
MESH:D008569 Memory Disorders Curcumin 4.9417263510
MESH:D009101 Multiple Myeloma Curcumin 3.8919372569
MESH:D009134 Muscular Atrophy, Spinal Curcumin 6.0117962980
MESH:D009361 Neoplasm Invasiveness Curcumin 5.1618495463
MESH:D009376 Neoplasms, Hormone-Dependent Curcumin 5.9512497104
MESH:D009423 Nervous System Neoplasms Curcumin 7.0518462866
MESH:D009765 Obesity Curcumin 2.8419297423
MESH:D010024 Osteoporosis Curcumin 3.7718719352
MESH:D010051 Ovarian Neoplasms Curcumin 2.9418462866 19020741
MESH:D010190 Pancreatic Neoplasms Curcumin 3.0819401701 17440100 19196508
MESH:D011471 Prostatic Neoplasms Curcumin 3.6011398177 10851300 15129424 18156803 18226269 18769126 12497104
MESH:D011656 Pulmonary Emphysema Curcumin 5.1019168576
MESH:D012128 Respiratory Distress Syndrome, Adult Curcumin 4.7210666014 18379247
MESH:D012509 Sarcoma Curcumin 4.6918462866
MESH:D018805 Sepsis Curcumin 4.5618389075
MESH:D013276 Stomach Ulcer Curcumin 4.1219188055 16631530
MESH:D001749 Urinary Bladder Neoplasms Curcumin 3.0518593936
MESH:D014565 Urogenital Neoplasms Curcumin 6.3518462866
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018