AutismKB 2.0

Annotation Detail for COL1A2


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:COL1A2 ( OI4 )
Gene Full Name: collagen, type I, alpha 2
Band: 7q21.3
Quick LinksEntrez ID:1278; OMIM: 120160; Uniprot ID:CO1A2_HUMAN; ENSEMBL ID: ENSG00000164692; HGNC ID: 2198
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa05146Amoebiasis
hsa04974Protein digestion and absorption
hsa04512ECM-receptor interaction
hsa04510Focal adhesion
Pathway IDPathway Name
Axon guidance
Hemostasis
Signaling by PDGF
Integrin cell surface interactions
Pathway IDPathway Name
200171Validated targets of C-MYC transcriptional repression
200188VEGFR3 signaling in lymphatic endothelium
200002Regulation of nuclear SMAD2/3 signaling
200004Endothelins
200130C-MYB transcription factor network
200018IL4-mediated signaling events
200118AP-1 transcription factor network
200044Validated transcriptional targets of AP1 family members Fra1 and Fra2
Pathway IDPathway Name
P00034Integrin signalling pathway
Pathway IDPathway Name
500004Integrin cell surface interactions
Related Diseases/Disorders Top
No data
No data
Desease Name
CARDIOVASCULAR
Osteoporosis
blood pressure, arterial hypertension
bone mass
mean forced vital capacity from 2 exams
systemic sclerosis
fractures
METABOLIC
brain aneurysm
osteogenesis imperfecta
intracranial aneurysms
Desease Name
Mean forced vital capacity from 2 exams
Desease Name
Ehlers-Danlos syndrome, cardiac valvular form
Ehlers-Danlos syndrome, type VIIB
Osteoporosis, postmenopausal
Osteogenesis imperfecta, 4 clinical forms
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C085911 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [FGF2 protein results in increased stability of and results in increased expression of COL1A2 protein]decreases reaction|increases expression|increases stability 16303940
C085911 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in decreased stability of and results in decreased expression of COL1A2 mRNAdecreases expression|decreases stability 16303940
C029955 2-nitrotoluene 2-nitrotoluene results in decreased expression of COL1A2 mRNAdecreases expression 16460773
C502971 2-phenyl-4-(3-pyridin-2-yl-1H-pyrazol-4-yl)pyridine 2-phenyl-4-(3-pyridin-2-yl-1H-pyrazol-4-yl)pyridine inhibits the reaction [Dimethylnitrosamine results in increased expression of COL1A2 mRNA]decreases reaction|increases expression 15723089
C030601 4-hydroxymercuribenzoate 4-hydroxymercuribenzoate inhibits the reaction [Acetaldehyde results in increased expression of COL1A2 mRNA]decreases reaction|increases expression 11343241
C105260 4-tert-octylphenol 4-tert-octylphenol results in increased expression of COL1A2 mRNAincreases expression 17011747
C008500 5'-methylthioadenosine 5'-methylthioadenosine results in decreased expression of COL1A2 mRNAdecreases expression 15983038
D000079 Acetaldehyde 4-hydroxymercuribenzoate inhibits the reaction [Acetaldehyde results in increased expression of COL1A2 mRNA]decreases reaction|increases expression 11343241
D000079 Acetaldehyde Acetaldehyde results in increased expression of COL1A2 mRNAincreases expression 16025520
11343241
D000079 Acetaldehyde calphostin C inhibits the reaction [Acetaldehyde results in increased expression of COL1A2 mRNA]decreases reaction|increases expression 11343241
D000079 Acetaldehyde PD 98059 inhibits the reaction [Acetaldehyde results in increased expression of COL1A2 mRNA]decreases reaction|increases expression 11343241
D000079 Acetaldehyde Sirolimus inhibits the reaction [Acetaldehyde results in increased expression of COL1A2 mRNA]decreases reaction|increases expression 11343241
D000079 Acetaldehyde SMAD3 protein promotes the reaction [Acetaldehyde results in increased expression of COL1A2 mRNA]increases expression|increases reaction 16025520
D000079 Acetaldehyde SMAD4 protein promotes the reaction [Acetaldehyde results in increased expression of COL1A2 mRNA]increases expression|increases reaction 16025520
D000079 Acetaldehyde SP1 protein promotes the reaction [Acetaldehyde results in increased expression of COL1A2 mRNA]increases expression|increases reaction 16025520
D000079 Acetaldehyde wortmannin inhibits the reaction [Acetaldehyde results in increased expression of COL1A2 mRNA]decreases reaction|increases expression 11343241
D000079 Acetaldehyde Acetaldehyde promotes the reaction [NFIC protein binds to COL1A2 promoter]affects binding|increases reaction 7768510
D000079 Acetaldehyde Acetaldehyde results in increased expression of COL1A2 mRNAincreases expression 10069557
9143363
8660697
7768510
15130784
10729205
8294106
D000079 Acetaldehyde calphostin C inhibits the reaction [Acetaldehyde results in increased expression of COL1A2 mRNA]decreases reaction|increases expression 10069557
D000079 Acetaldehyde LEP protein affects the reaction [Acetaldehyde results in increased expression of COL1A2 mRNA]affects reaction|increases expression 15130784
D000079 Acetaldehyde NFIC protein promotes the reaction [Acetaldehyde results in increased expression of COL1A2 mRNA]increases expression|increases reaction 7768510
D000079 Acetaldehyde Tretinoin inhibits the reaction [Acetaldehyde results in increased expression of COL1A2 mRNA]decreases reaction|increases expression 10729205
D000079 Acetaldehyde tricyclodecane-9-yl-xanthogenate inhibits the reaction [Acetaldehyde results in increased expression of COL1A2 mRNA]decreases reaction|increases expression 10069557
D000082 Acetaminophen Acetaminophen affects the expression of COL1A2 mRNAaffects expression 17562736
C056165 acetovanillone acetovanillone inhibits the reaction [AGT protein results in increased expression of COL1A2 mRNA]decreases reaction|increases expression 16531806
C056165 acetovanillone acetovanillone inhibits the reaction [AGT protein results in increased expression of COL1A2 protein]decreases reaction|increases expression 16531806
D000111 Acetylcysteine Acetylcysteine results in decreased expression of COL1A2 mRNAdecreases expression 11710721
D012435 S-Adenosylhomocysteine S-Adenosylhomocysteine results in decreased expression of COL1A2 mRNAdecreases expression 15983038
D012436 S-Adenosylmethionine S-Adenosylmethionine results in decreased expression of COL1A2 mRNAdecreases expression 15983038
D012436 S-Adenosylmethionine S-Adenosylmethionine inhibits the reaction [Carbon Tetrachloride results in increased expression of COL1A2 mRNA]decreases reaction|increases expression 15983038
D012436 S-Adenosylmethionine S-Adenosylmethionine inhibits the reaction [SP1 protein binds to COL1A2 promoter]affects binding|decreases reaction 15983038
D012436 S-Adenosylmethionine S-Adenosylmethionine inhibits the reaction [TGFB1 protein binds to COL1A2 promoter]affects binding|decreases reaction 15983038
C103303 alitretinoin alitretinoin results in increased expression of COL1A2 mRNAincreases expression 16648578
D000537 Aluminum Oxide Aluminum Oxide results in increased expression of COL1A2 mRNAincreases expression 19464052
C006632 arsenic trioxide arsenic trioxide results in decreased expression of COL1A2 mRNAdecreases expression 20458559
C006632 arsenic trioxide [Tetradecanoylphorbol Acetate co-treated with arsenic trioxide] results in increased expression of COL1A2 mRNAaffects cotreatment|increases expression 18922899
C015001 arsenite arsenite results in increased expression of COL1A2 mRNAincreases expression 18296743
C015001 arsenite Dietary Fats promotes the reaction [arsenite results in increased expression of COL1A2 mRNA]increases expression|increases reaction 18296743
C006680 baicalein baicalein inhibits the reaction [TGFB1 protein results in increased expression of COL1A2 mRNA]decreases reaction|increases expression 19474275
C038044 baicalin baicalin inhibits the reaction [TGFB1 protein results in increased expression of COL1A2 mRNA]decreases reaction|increases expression 19474275
C031463 beta-glycerophosphoric acid beta-glycerophosphoric acid results in decreased expression of COL1A2 mRNAdecreases expression 17171500
C031463 beta-glycerophosphoric acid Calcitriol promotes the reaction [beta-glycerophosphoric acid results in decreased expression of COL1A2 mRNA]decreases expression|increases reaction 17171500
C031463 beta-glycerophosphoric acid paricalcitol promotes the reaction [beta-glycerophosphoric acid results in decreased expression of COL1A2 mRNA]decreases expression|increases reaction 17171500
C099813 bromochloroacetic acid bromochloroacetic acid results in decreased expression of COL1A2 mRNAdecreases expression 16460773
D020122 tert-Butylhydroperoxide tert-Butylhydroperoxide results in decreased expression of COL1A2 mRNAdecreases expression 15336504
D002118 Calcium COL1A2 protein affects the abundance of Calciumaffects abundance 10913914
C058819 calphostin C calphostin C inhibits the reaction [Acetaldehyde results in increased expression of COL1A2 mRNA]decreases reaction|increases expression 11343241
C058819 calphostin C calphostin C inhibits the reaction [Acetaldehyde results in increased expression of COL1A2 mRNA]decreases reaction|increases expression 10069557
D002251 Carbon Tetrachloride Carbon Tetrachloride results in increased expression of COL1A2 mRNAincreases expression 17484886
15983038
17105591
15056808
17011172
14512876
18395096
16012952
D002251 Carbon Tetrachloride CYBB gene mutant form inhibits the reaction [Carbon Tetrachloride results in increased expression of COL1A2 mRNA]decreases reaction|increases expression 17105591
D002251 Carbon Tetrachloride HGF protein inhibits the reaction [Carbon Tetrachloride results in increased expression of COL1A2 mRNA]decreases reaction|increases expression 18395096
D002251 Carbon Tetrachloride IFNA1 protein inhibits the reaction [Carbon Tetrachloride results in increased expression of COL1A2 mRNA]decreases reaction|increases expression 14512876
D002251 Carbon Tetrachloride S-Adenosylmethionine inhibits the reaction [Carbon Tetrachloride results in increased expression of COL1A2 mRNA]decreases reaction|increases expression 15983038
D002251 Carbon Tetrachloride Tretinoin inhibits the reaction [Carbon Tetrachloride results in increased expression of COL1A2 mRNA]decreases reaction|increases expression 17011172
D002251 Carbon Tetrachloride YBX1 protein inhibits the reaction [Carbon Tetrachloride results in increased expression of COL1A2 mRNA]decreases reaction|increases expression 16012952
D002251 Carbon Tetrachloride [Carbon Tetrachloride co-treated with Folic Acid] results in increased expression of COL1A2 mRNAaffects cotreatment|increases expression 18156304
D002251 Carbon Tetrachloride Carbon Tetrachloride results in increased expression of COL1A2 mRNAincreases expression 18481824
17056239
D002251 Carbon Tetrachloride Carbon Tetrachloride results in increased expression of COL1A2 proteinincreases expression 17631135
D002251 Carbon Tetrachloride [imatinib co-treated with Perindopril] inhibits the reaction [Carbon Tetrachloride affects the expression of COL1A2 mRNA]affects cotreatment|affects expression|decreases reaction 16596278
D002251 Carbon Tetrachloride imatinib inhibits the reaction [Carbon Tetrachloride affects the expression of COL1A2 mRNA]affects expression|decreases reaction 16596278
D002251 Carbon Tetrachloride Perindopril inhibits the reaction [Carbon Tetrachloride affects the expression of COL1A2 mRNA]affects expression|decreases reaction 16596278
D002251 Carbon Tetrachloride PLAU protein inhibits the reaction [Carbon Tetrachloride results in increased expression of COL1A2 mRNA]decreases reaction|increases expression 18481824
D002995 Clofibric Acid Clofibric Acid affects the expression of COL1A2 mRNAaffects expression 17602206
C402665 CP 31398 CP 31398 results in increased expression of COL1A2 mRNAincreases expression 15155752
D003474 Curcumin Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of COL1A2 mRNA]decreases reaction|increases expression 18200517
D003609 Dactinomycin Dactinomycin inhibits the reaction [LEP protein results in increased expression of COL1A2 mRNA]decreases reaction|increases expression 12704794
C014347 decitabine decitabine results in decreased methylation of COL1A2 promoterdecreases methylation 19424577
C014347 decitabine decitabine results in increased expression of COL1A2 mRNAincreases expression 19424577
D004041 Dietary Fats Dietary Fats promotes the reaction [arsenite results in increased expression of COL1A2 mRNA]increases expression|increases reaction 18296743
D004041 Dietary Fats Dietary Fats results in increased expression of COL1A2 mRNAincreases expression 18296743
D004041 Dietary Fats Dietary Fats results in increased expression of COL1A2 mRNAincreases expression 18042831
D004052 Diethylnitrosamine Diethylnitrosamine results in increased expression of COL1A2 mRNAincreases expression 19638242
D004054 Diethylstilbestrol Diethylstilbestrol results in increased expression of COL1A2 mRNAincreases expression 16086434
D004054 Diethylstilbestrol Diethylstilbestrol results in increased expression of COL1A2 proteinincreases expression 16086434
D004054 Diethylstilbestrol Diethylstilbestrol results in increased expression of COL1A2 mRNAincreases expression 17011747
D002117 Calcitriol Calcitriol promotes the reaction [beta-glycerophosphoric acid results in decreased expression of COL1A2 mRNA]decreases expression|increases reaction 17171500
D004128 Dimethylnitrosamine 2-phenyl-4-(3-pyridin-2-yl-1H-pyrazol-4-yl)pyridine inhibits the reaction [Dimethylnitrosamine results in increased expression of COL1A2 mRNA]decreases reaction|increases expression 15723089
D004128 Dimethylnitrosamine Dimethylnitrosamine affects the expression of COL1A2 mRNAaffects expression 16979622
D004128 Dimethylnitrosamine Dimethylnitrosamine results in increased expression of COL1A2 mRNAincreases expression 17724770
16604421
15723089
D004128 Dimethylnitrosamine Plant Preparations inhibits the reaction [Dimethylnitrosamine results in increased expression of COL1A2 mRNA]decreases reaction|increases expression 17724770
D004128 Dimethylnitrosamine Silymarin inhibits the reaction [Dimethylnitrosamine results in increased expression of COL1A2 mRNA]decreases reaction|increases expression 16604421
17724770
D004128 Dimethylnitrosamine Thalidomide inhibits the reaction [Dimethylnitrosamine results in increased expression of COL1A2 mRNA]decreases reaction|increases expression 16604421
D004365 Drugs, Chinese Herbal Drugs, Chinese Herbal inhibits the reaction [TGFB1 protein results in increased expression of COL1A2 mRNA]decreases reaction|increases expression 19474275
D004642 Emodin Emodin inhibits the reaction [TGFB1 protein results in increased expression of COL1A2 mRNA]decreases reaction|increases expression 19474275
D004958 Estradiol Estradiol results in decreased expression of COL1A2 mRNAdecreases expression 19401787
D000431 Ethanol Ethanol inhibits the reaction [sodium arsenite results in increased expression of COL1A2 mRNA]decreases reaction|increases expression 18182400
D000431 Ethanol [Fish Oils co-treated with Ethanol] results in increased expression of COL1A2 mRNAaffects cotreatment|increases expression 17347304
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of COL1A2 mRNAincreases expression 17942748
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of COL1A2 mRNAaffects cotreatment|increases expression 17942748
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of COL1A2 mRNAincreases expression 12655037
D005395 Fish Oils [Fish Oils co-treated with Ethanol] results in increased expression of COL1A2 mRNAaffects cotreatment|increases expression 17347304
D005419 Flavonoids Flavonoids results in decreased expression of COL1A2 mRNAdecreases expression 18035473
D005459 Fluorides COL1A2 protein affects the abundance of Fluoridesaffects abundance 10913914
D005492 Folic Acid [Carbon Tetrachloride co-treated with Folic Acid] results in increased expression of COL1A2 mRNAaffects cotreatment|increases expression 18156304
D019833 Genistein Genistein results in decreased expression of COL1A2 mRNAdecreases expression 12075121
C010176 halofuginone halofuginone inhibits the reaction [TGFB1 protein results in increased expression of COL1A2 mRNA]decreases reaction|increases expression 11874485
C010176 halofuginone halofuginone results in decreased expression of COL1A2 mRNAdecreases expression 11874485
C513449 icarisid II icarisid II results in increased expression of COL1A2 mRNAincreases expression 17764702
C499403 icaritin icaritin results in increased expression of COL1A2 mRNAincreases expression 17764702
C097613 imatinib [imatinib co-treated with Perindopril] inhibits the reaction [Carbon Tetrachloride affects the expression of COL1A2 mRNA]affects cotreatment|affects expression|decreases reaction 16596278
C097613 imatinib imatinib inhibits the reaction [Carbon Tetrachloride affects the expression of COL1A2 mRNA]affects expression|decreases reaction 16596278
D019266 Iron, Dietary Iron, Dietary affects the reaction [Thioacetamide affects the expression of COL1A2 mRNA]affects expression|affects reaction 18032466
D008274 Magnesium Magnesium results in increased expression of COL1A2 proteinincreases expression 10397942
D008274 Magnesium COL1A2 protein affects the abundance of Magnesiumaffects abundance 10913914
D008315 Malondialdehyde Malondialdehyde results in increased expression of COL1A2 mRNAincreases expression 11295527
D008315 Malondialdehyde MAPK8 protein promotes the reaction [Malondialdehyde results in increased expression of COL1A2 mRNA]increases expression|increases reaction 11295527
D008713 Methimazole Methimazole results in decreased expression of COL1A2 mRNAdecreases expression 17403546
D008713 Methimazole Methimazole results in increased expression of COL1A2 mRNAincreases expression 17399805
D010126 Ozone Ozone results in increased expression of COL1A2 mRNAincreases expression 16716893
D017239 Paclitaxel Paclitaxel results in increased expression of COL1A2 mRNAincreases expression 19682730
C041786 palm oil palm oil results in increased expression of COL1A2 mRNAincreases expression 18042831
C084656 paricalcitol paricalcitol promotes the reaction [beta-glycerophosphoric acid results in decreased expression of COL1A2 mRNA]decreases expression|increases reaction 17171500
C093973 PD 98059 PD 98059 inhibits the reaction [Acetaldehyde results in increased expression of COL1A2 mRNA]decreases reaction|increases expression 11343241
C494474 perchlorate perchlorate results in decreased expression of COL1A2 mRNAdecreases expression 17403546
C494474 perchlorate perchlorate results in increased expression of COL1A2 mRNAincreases expression 17399805
D020913 Perindopril [imatinib co-treated with Perindopril] inhibits the reaction [Carbon Tetrachloride affects the expression of COL1A2 mRNA]affects cotreatment|affects expression|decreases reaction 16596278
D020913 Perindopril Perindopril inhibits the reaction [Carbon Tetrachloride affects the expression of COL1A2 mRNA]affects expression|decreases reaction 16596278
D010634 Phenobarbital NR1I3 protein affects the reaction [Phenobarbital results in increased expression of COL1A2 mRNA]affects reaction|increases expression 19482888
D010634 Phenobarbital Phenobarbital results in increased expression of COL1A2 mRNAincreases expression 19482888
D010710 Phosphates COL1A2 protein affects the abundance of Phosphatesaffects abundance 10913914
D028321 Plant Preparations Plant Preparations inhibits the reaction [Dimethylnitrosamine results in increased expression of COL1A2 mRNA]decreases reaction|increases expression 17724770
D011374 Progesterone Progesterone results in decreased expression of COL1A2 mRNAdecreases expression 18070364
D011441 Propylthiouracil Propylthiouracil results in decreased expression of COL1A2 mRNAdecreases expression 17403546
D011441 Propylthiouracil Propylthiouracil results in increased expression of COL1A2 mRNAincreases expression 17399805
D011794 Quercetin Quercetin inhibits the reaction [TGFB1 protein results in increased expression of COL1A2 mRNA]decreases reaction|increases expression 19474275
D020849 Raloxifene Raloxifene results in decreased expression of COL1A2 mRNAdecreases expression 19401787
C076944 salvianolic acid B salvianolic acid B inhibits the reaction [TGFB1 protein results in increased expression of COL1A2 mRNA]decreases reaction|increases expression 19474275
C002979 selenomethylselenocysteine selenomethylselenocysteine results in decreased expression of COL1A2 mRNAdecreases expression 18514395
C002979 selenomethylselenocysteine selenomethylselenocysteine results in decreased expression of COL1A2 proteindecreases expression 18514395
D017632 Asbestos, Serpentine Asbestos, Serpentine results in decreased expression of COL1A2 mRNAdecreases expression 16251409
D012838 Silymarin Silymarin inhibits the reaction [Dimethylnitrosamine results in increased expression of COL1A2 mRNA]decreases reaction|increases expression 17724770
16604421
D020123 Sirolimus Sirolimus inhibits the reaction [Acetaldehyde results in increased expression of COL1A2 mRNA]decreases reaction|increases expression 11343241
D012964 Sodium COL1A2 protein affects the abundance of Sodiumaffects abundance 10913914
C017947 sodium arsenite Ethanol inhibits the reaction [sodium arsenite results in increased expression of COL1A2 mRNA]decreases reaction|increases expression 18182400
C017947 sodium arsenite sodium arsenite results in increased expression of COL1A2 mRNAincreases expression 18182400
C017947 sodium arsenite sodium arsenite results in decreased expression of COL1A2 mRNAdecreases expression 18812580
C017947 sodium arsenite sodium arsenite results in increased expression of COL1A2 mRNAincreases expression 19095001
D013467 Sulindac Sulindac results in increased expression of COL1A2 mRNAincreases expression 18499699
D014284 Triiodothyronine Triiodothyronine results in increased expression of COL1A2 mRNAincreases expression 17403546
C004648 testosterone enanthate testosterone enanthate affects the expression of COL1A2 mRNAaffects expression 17440010
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of COL1A2 mRNAdecreases expression 17884332
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of COL1A2 mRNAaffects cotreatment|increases expression 17942748
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of COL1A2 mRNAdecreases expression 15667827
19465110
D013755 Tetradecanoylphorbol Acetate [Tetradecanoylphorbol Acetate co-treated with arsenic trioxide] results in increased expression of COL1A2 mRNAaffects cotreatment|increases expression 18922899
D013755 Tetradecanoylphorbol Acetate [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of COL1A2 mRNAaffects cotreatment|affects expression 16979875
D013792 Thalidomide Thalidomide inhibits the reaction [Dimethylnitrosamine results in increased expression of COL1A2 mRNA]decreases reaction|increases expression 16604421
D013792 Thalidomide Thalidomide inhibits the reaction [TNF protein results in increased expression of COL1A2 mRNA]decreases reaction|increases expression 16604421
D013853 Thioacetamide HGF protein inhibits the reaction [Thioacetamide results in increased expression of COL1A2 mRNA]decreases reaction|increases expression 10677585
D013853 Thioacetamide Iron, Dietary affects the reaction [Thioacetamide affects the expression of COL1A2 mRNA]affects expression|affects reaction 18032466
D013853 Thioacetamide Thioacetamide results in increased expression of COL1A2 mRNAincreases expression 10677585
D014212 Tretinoin Tretinoin inhibits the reaction [Acetaldehyde results in increased expression of COL1A2 mRNA]decreases reaction|increases expression 10729205
D014212 Tretinoin Tretinoin inhibits the reaction [Carbon Tetrachloride results in increased expression of COL1A2 mRNA]decreases reaction|increases expression 17011172
D014212 Tretinoin Tretinoin results in decreased expression of COL1A2 mRNAdecreases expression 10729205
D014212 Tretinoin Tretinoin results in decreased expression of COL1A2 mRNAdecreases expression 15234273
C046498 tricyclodecane-9-yl-xanthogenate tricyclodecane-9-yl-xanthogenate inhibits the reaction [Acetaldehyde results in increased expression of COL1A2 mRNA]decreases reaction|increases expression 10069557
D014302 Trinitrobenzenesulfonic Acid Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of COL1A2 mRNA]decreases reaction|increases expression 18200517
D014302 Trinitrobenzenesulfonic Acid Trinitrobenzenesulfonic Acid results in increased expression of COL1A2 mRNAincreases expression 17982090
18200517
C066075 vanadium pentoxide vanadium pentoxide results in decreased expression of COL1A2 mRNAdecreases expression 17459161
C009687 wortmannin wortmannin inhibits the reaction [Acetaldehyde results in increased expression of COL1A2 mRNA]decreases reaction|increases expression 11343241
D015032 Zinc [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of COL1A2 mRNAaffects cotreatment|affects expression 16979875
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Sulindac 4.6914745880
MESH:D000014 Abnormalities, Drug-Induced Ethanol 13.9818926900 17676605
MESH:D000014 Abnormalities, Drug-Induced Phenobarbital 13.986195326
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 13.9814514962 11752688 15322242
MESH:D000014 Abnormalities, Drug-Induced Thalidomide 13.988333272
MESH:D000015 Abnormalities, Multiple imatinib 4.5318322153
MESH:D000022 Abortion, Spontaneous imatinib 5.4018322153
MESH:D000038 Abscess Drugs, Chinese Herbal 5.5015043669
MESH:D000138 Acidosis Ethanol 3.7111192467
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.1317505938
MESH:D000169 Acrodermatitis Zinc 4.6117190629 16889938 17202136
MESH:D058186 Acute Kidney Injury Folic Acid 6.8216316344 17003819 16595132
MESH:D058186 Acute Kidney Injury Sulindac 6.827897758
MESH:D000230 Adenocarcinoma arsenic trioxide 13.3219825857 11798837
MESH:D000230 Adenocarcinoma Dimethylnitrosamine 13.3216033868
MESH:D000230 Adenocarcinoma Estradiol 13.3211473722
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 13.3214692618
MESH:D000230 Adenocarcinoma Genistein 13.3211473722
MESH:D000230 Adenocarcinoma Sulindac 13.3211910360
MESH:D000236 Adenoma Diethylnitrosamine 15.556695378 10737359
MESH:D000236 Adenoma Dimethylnitrosamine 15.5519555203
MESH:D000236 Adenoma Folic Acid 15.5516963246
MESH:D000236 Adenoma Magnesium 15.5517823441
MESH:D000236 Adenoma Sulindac 15.5510223192
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 12.7819061943 18056438 17620307 16434500 17162532 19052882
MESH:D018248 Adenoma, Liver Cell Phenobarbital 12.7817620307
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 12.7816835633
MESH:D011125 Adenomatous Polyposis Coli Sulindac 3.9019003578 11874996 16460482 11535846 15623613 17611924 12394442
MESH:D000310 Adrenal Gland Neoplasms sodium arsenite 3.8915276417
MESH:D018246 Adrenocortical Adenoma sodium arsenite 4.0917306315 16712894
MESH:D000419 Albuminuria Raloxifene 3.8417451421 17308373
MESH:D020268 Alcohol-Induced Disorders, Nervous System Ethanol 4.5115451039 15451040
MESH:D019973 Alcohol-Related Disorders Curcumin 4.2717887948
MESH:D000505 Alopecia Tretinoin 2.9615955085
MESH:D000544 Alzheimer Disease Curcumin 9.6815590663
MESH:D000544 Alzheimer Disease Folic Acid 9.6817116317
MESH:D000544 Alzheimer Disease Ozone 9.6815513908
MESH:D000544 Alzheimer Disease Raloxifene 9.6815800139
MESH:D000544 Alzheimer Disease Zinc 9.6816410023 16325427 16580781 17119284
MESH:D000686 Amyloidosis Diethylstilbestrol 3.7215469931
MESH:D000690 Amyotrophic Lateral Sclerosis Thalidomide 3.8116510725
MESH:D000740 Anemia Drugs, Chinese Herbal 11.1417963324 15504547
MESH:D000740 Anemia Malondialdehyde 11.1417278206
MESH:D000740 Anemia Tetrachlorodibenzodioxin 11.1411748828
MESH:D000743 Anemia, Hemolytic Quercetin 3.5217084956
MESH:D000755 Anemia, Sickle Cell Zinc 4.1416916123
MESH:D000787 Angina Pectoris Drugs, Chinese Herbal 4.6111477813
MESH:D000799 Angioedema Acetaminophen 3.0410982225
MESH:D000853 Anophthalmos Ethanol 4.0415513904
MESH:D001004 Anus Diseases Drugs, Chinese Herbal 5.1615043669
MESH:D001008 Anxiety Disorders Ethanol 3.3511141031
MESH:D001161 Arteriosclerosis Dietary Fats 7.3415238619
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 7.3411256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 9.1915885639
MESH:D001169 Arthritis, Experimental Thalidomide 9.199598899
MESH:D001169 Arthritis, Experimental Tretinoin 9.1916412693
MESH:D015210 Arthritis, Gouty Drugs, Chinese Herbal 4.9519655406
MESH:D001172 Arthritis, Rheumatoid Curcumin 5.8516807698
MESH:D001172 Arthritis, Rheumatoid Ozone 5.8515570426
MESH:D001172 Arthritis, Rheumatoid Tretinoin 5.8516292516
MESH:D001195 Asbestosis Asbestos, Serpentine 4.9110751356
MESH:D001249 Asthma Acetaldehyde 8.619600491
MESH:D001249 Asthma Ozone 8.6116373670 17854713
MESH:D001249 Asthma Tretinoin 8.6116456186
MESH:D001249 Asthma Zinc 8.6117085522
MESH:D001260 Ataxia Telangiectasia Quercetin 4.1815336622
MESH:D050197 Atherosclerosis Curcumin 2.8118704882
MESH:D001321 Autistic Disorder Acetaminophen 3.7318445737
MESH:D001321 Autistic Disorder Folic Acid 3.7321388746
MESH:D001321 Autistic Disorder Magnesium 3.7316846101
MESH:D001321 Autistic Disorder S-Adenosylhomocysteine 3.7320468076 16917939
MESH:D001321 Autistic Disorder S-Adenosylmethionine 3.7319056591 16917939
MESH:D001321 Autistic Disorder Sirolimus 3.7321115397
MESH:D001327 Autoimmune Diseases Curcumin 8.2919761891
MESH:D001327 Autoimmune Diseases Quercetin 8.2919761891
MESH:D001471 Barrett Esophagus Tretinoin 3.6416935849
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 21.2716206674
MESH:D001778 Blood Coagulation Disorders Propylthiouracil 21.2719483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 21.2712125929
MESH:D001778 Blood Coagulation Disorders Thioacetamide 21.2719483382
MESH:D001778 Blood Coagulation Disorders Tretinoin 21.2716206674 16197459
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 2.9815340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.2015746008
MESH:D019046 Bone Marrow Neoplasms Dactinomycin 4.7314601052
MESH:D001859 Bone Neoplasms imatinib 8.5215867366
MESH:D001859 Bone Neoplasms Paclitaxel 8.5215867366
MESH:D001862 Bone Resorption Drugs, Chinese Herbal 4.109881647
MESH:D001913 Bowen's Disease Sulindac 4.5511207687
MESH:D020201 Brain Hemorrhage, Traumatic Progesterone 4.5317868700
MESH:D001930 Brain Injuries Progesterone 13.9915665606 15380490 15845082
MESH:D001930 Brain Injuries Raloxifene 13.9916580743
MESH:D001930 Brain Injuries Zinc 13.9917109824
MESH:D002545 Brain Ischemia Curcumin 3.5416770732
MESH:D001932 Brain Neoplasms Curcumin 3.2417596214
MESH:D001943 Breast Neoplasms alitretinoin 19.7616344269
MESH:D001943 Breast Neoplasms Calcitriol 19.7611237771
MESH:D001943 Breast Neoplasms Curcumin 19.7619250217 18593918 16243823 18462866
MESH:D001943 Breast Neoplasms decitabine 19.7618320071 19208741
MESH:D001943 Breast Neoplasms Dietary Fats 19.7620435547
MESH:D001943 Breast Neoplasms Diethylnitrosamine 19.7617474063
MESH:D001943 Breast Neoplasms Diethylstilbestrol 19.7617129689 15324884
MESH:D001943 Breast Neoplasms Estradiol 19.7612948864 18497071 16675129 17261762 17289903 17018787 14630087 19861407
MESH:D001943 Breast Neoplasms Folic Acid 19.7616777985
MESH:D001943 Breast Neoplasms Genistein 19.7616873071 16541309 17200150
MESH:D001943 Breast Neoplasms imatinib 19.7617614352
MESH:D001943 Breast Neoplasms Paclitaxel 19.7618323546 16273361 11325840 16244791 15136595 16115903 18223236 18234424
MESH:D001943 Breast Neoplasms Plant Preparations 19.7617398067
MESH:D001943 Breast Neoplasms Progesterone 19.7617614352 15562024 16175315
MESH:D001943 Breast Neoplasms Quercetin 19.7618628248
MESH:D001943 Breast Neoplasms Raloxifene 19.7617261762 15572757 17595753 17893378 17952589 15758505 16837676 16912660 17049068 17242785 17440819 15775269
MESH:D001943 Breast Neoplasms selenomethylselenocysteine 19.7618855134
MESH:D001943 Breast Neoplasms Sulindac 19.7616642371
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 19.7620435547
MESH:D001943 Breast Neoplasms Tretinoin 19.7616166294 16873071 16443354
MESH:D016535 Bronchial Hyperreactivity Ozone 3.0315516495 17626835 18417511 16777450 18315731 14754758 19059883
MESH:D001991 Bronchitis vanadium pentoxide 5.4317459161
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 3.8016813970
MESH:D002051 Burkitt Lymphoma arsenic trioxide 3.5911589617
MESH:D002056 Burns Ethanol 3.8816374292
MESH:D002100 Cachexia Ozone 3.9516183385
MESH:D002105 Cadmium Poisoning Quercetin 4.7416962696
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 3.6716111702
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 8.1216192424 15700767 16124888 15721981 16011737 16050911 10355542 15673190 3786805 16227642 18705752 16097048
MESH:D002252 Carbon Tetrachloride Poisoning Perindopril 8.1216097048
MESH:D002277 Carcinoma Curcumin 10.2618593918
MESH:D002277 Carcinoma Dimethylnitrosamine 10.2619555203
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 10.2616835633
MESH:D018236 Carcinoma, Embryonal Tretinoin 4.3516168501
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 35.993084413
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 35.9916217749 15073043 14691202 11135700 15553829
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 35.9918788625
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 35.9921159647 19052882 19822196 16569478 16779866 18210153 11831363 17978847 19539802 18506893 20007298 20727157 19701751 19171122 18393292 16935385 20524982 17138121 19394651 20214788 18788625 17761372 20935162 3084413 16878318 19208518 10672840 16288022 3581430 17173139 16698587 16328049 18691550 16502159 16681979 19919837 19519916 18056438 20512989 19335982 18971187 20432363 18785209 19107877 17162532 20084675 18665156 16540662 17055752 16830150 19383236 18978308 20101231 10737359 19418558 17428255 16807293 18494052 20514400
MESH:D006528 Carcinoma, Hepatocellular Diethylstilbestrol 35.9916924424 15948411
MESH:D006528 Carcinoma, Hepatocellular Estradiol 35.9916924424
MESH:D006528 Carcinoma, Hepatocellular Ethanol 35.9915289165 18788625 15763234
MESH:D006528 Carcinoma, Hepatocellular Genistein 35.9916924424
MESH:D006528 Carcinoma, Hepatocellular Paclitaxel 35.9916313753
MESH:D006528 Carcinoma, Hepatocellular Phenobarbital 35.991701930 17173139 20935162 20007298 6705139
MESH:D006528 Carcinoma, Hepatocellular Quercetin 35.9912508355 19519916
MESH:D006528 Carcinoma, Hepatocellular Sirolimus 35.9919335982
MESH:D006528 Carcinoma, Hepatocellular sodium arsenite 35.9915276417 17306315 16507464
MESH:D006528 Carcinoma, Hepatocellular Thalidomide 35.9916313753
MESH:D006528 Carcinoma, Hepatocellular Thioacetamide 35.9917997003
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 35.991917145
MESH:D002289 Carcinoma, Non-Small-Cell Lung Curcumin 2.6418414057
MESH:D021441 Carcinoma, Pancreatic Ductal Quercetin 4.1817234771
MESH:D002291 Carcinoma, Papillary arsenic trioxide 4.0619014326
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 3.4112490120
MESH:D002294 Carcinoma, Squamous Cell Acetylcysteine 31.1117015178
MESH:D002294 Carcinoma, Squamous Cell Calcitriol 31.1111237771
MESH:D002294 Carcinoma, Squamous Cell Curcumin 31.1118462866
MESH:D002294 Carcinoma, Squamous Cell decitabine 31.1119215824
MESH:D002294 Carcinoma, Squamous Cell Dimethylnitrosamine 31.1116033868
MESH:D002294 Carcinoma, Squamous Cell Plant Preparations 31.1117418620
MESH:D002294 Carcinoma, Squamous Cell Sirolimus 31.1119435901
MESH:D002294 Carcinoma, Squamous Cell sodium arsenite 31.1118572023
MESH:D002294 Carcinoma, Squamous Cell Tetradecanoylphorbol Acetate 31.1118922899
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 31.1116096774 16051514
MESH:D002294 Carcinoma, Squamous Cell Zinc 31.1116543248
MESH:D002295 Carcinoma, Transitional Cell Raloxifene 3.3717572228
MESH:D006332 Cardiomegaly Ethanol 8.5119332462
MESH:D006332 Cardiomegaly Quercetin 8.5119794523
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 8.5118670907 16120746 18850075
MESH:D002310 Cardiomyopathy, Alcoholic Acetaldehyde 5.6710525098
MESH:D002318 Cardiovascular Diseases Folic Acid 16.5216755160
MESH:D002318 Cardiovascular Diseases Genistein 16.5216332659
MESH:D002318 Cardiovascular Diseases Plant Preparations 16.5216862667
MESH:D002318 Cardiovascular Diseases Raloxifene 16.5215775269
MESH:D002318 Cardiovascular Diseases Zinc 16.5216936243
MESH:D016893 Carotid Stenosis Plant Preparations 5.3415158307
MESH:D002386 Cataract Acetaminophen 5.4610977129
MESH:D002386 Cataract Tretinoin 5.4617460283
MESH:D002430 Cecal Neoplasms 2-nitrotoluene 4.9514688030
MESH:D002471 Cell Transformation, Neoplastic Acetylcysteine 11.2618226522
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 11.262727394 17174075 7505956 21159647
MESH:D002471 Cell Transformation, Neoplastic Estradiol 11.2618566989
MESH:D002471 Cell Transformation, Neoplastic sodium arsenite 11.2619524636 20056578
MESH:D002493 Central Nervous System Diseases Phenobarbital 3.484080065
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 3.8016129372
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 17.5019052882
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 17.5016835633
MESH:D018281 Cholangiocarcinoma Thalidomide 17.5018291259
MESH:D018281 Cholangiocarcinoma Thioacetamide 17.5018291259
MESH:D002779 Cholestasis Ethinyl Estradiol 2.2616919318 15861022 16105132 17110522 17681005 11677210 17333356
MESH:D002822 Choriocarcinoma Tretinoin 4.3516461808
MESH:D002971 Cleft Lip Ethanol 6.2615513904
MESH:D002971 Cleft Lip Folic Acid 6.2621254359
MESH:D002972 Cleft Palate Ethanol 10.7015513904
MESH:D002972 Cleft Palate Folic Acid 10.708946559 21254359
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 10.7012621046 16354765 15668235 8697196 15340226
MESH:D002972 Cleft Palate Tretinoin 10.709407595
MESH:D003072 Cognition Disorders Raloxifene 3.8415800139
MESH:D003092 Colitis Curcumin 16.6216804969 18200517 16782535
MESH:D003092 Colitis Thalidomide 16.6216680017
MESH:D003092 Colitis Tretinoin 16.6217035595
MESH:D003092 Colitis Trinitrobenzenesulfonic Acid 16.6217991707 18200517 16867261 16804969 16782535 17936198 16474422 11698051 18023891
MESH:D003093 Colitis, Ulcerative Trinitrobenzenesulfonic Acid 3.1017276891
MESH:D003103 Coloboma Curcumin 3.8318809619
MESH:D003110 Colonic Neoplasms arsenite 11.0415037631
MESH:D003110 Colonic Neoplasms Curcumin 11.0419359593 16340194
MESH:D003110 Colonic Neoplasms decitabine 11.0417616700
MESH:D003110 Colonic Neoplasms Genistein 11.0417182828
MESH:D003110 Colonic Neoplasms Quercetin 11.0419440933 16640504 17148506 11134977 15741050 17191121 19056647
MESH:D003110 Colonic Neoplasms Sulindac 11.0412902858 12458338
MESH:D003111 Colonic Polyps Magnesium 5.2917823441
MESH:D015179 Colorectal Neoplasms arsenic trioxide 8.4520501625
MESH:D015179 Colorectal Neoplasms decitabine 8.4518981723
MESH:D015179 Colorectal Neoplasms Folic Acid 8.4517245555 17087956 17116713 16963246 16985020
MESH:D015179 Colorectal Neoplasms Magnesium 8.4517823441
MESH:D015179 Colorectal Neoplasms Paclitaxel 8.4518802399
MESH:D015179 Colorectal Neoplasms Quercetin 8.4518852136 18095365
MESH:D015179 Colorectal Neoplasms Sulindac 8.4510666051 11197048 18059344 11076880
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 2.3814669216 17141729
MESH:D016510 Corneal Neovascularization Curcumin 10.0318497527
MESH:D016510 Corneal Neovascularization Thalidomide 10.039301478
MESH:D003324 Coronary Artery Disease Plant Preparations 3.6415158307
MESH:D023903 Coronary Restenosis arsenic trioxide 3.4312609071
MESH:D003389 Cranial Nerve Diseases Thalidomide 5.499200351
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 9.4910525206
MESH:D019465 Craniofacial Abnormalities Ethanol 9.4919302082 15451040 15451039 11198716 15513904 11873399 10194807
MESH:D019465 Craniofacial Abnormalities imatinib 9.4918322153
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 9.4920055451 10048152 15322242
MESH:D019465 Craniofacial Abnormalities Thalidomide 9.499200351
MESH:D019465 Craniofacial Abnormalities Tretinoin 9.4917551590 9125849 16925845 9211117 10589399 8800419 9664655 14991402 9142499 9224671
MESH:D019465 Craniofacial Abnormalities Zinc 9.4919302082
MESH:D003424 Crohn Disease Thalidomide 3.7116078585
MESH:D003456 Cryptorchidism Diethylstilbestrol 3.8012952375 16002989
MESH:D003550 Cystic Fibrosis Acetylcysteine 3.6919747007
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 3.3615213294
MESH:D003865 Depressive Disorder, Major Raloxifene 3.4817474826
MESH:D002658 Developmental Disabilities Magnesium 4.3316846101
MESH:D003920 Diabetes Mellitus Zinc 3.5216479319
MESH:D003921 Diabetes Mellitus, Experimental Quercetin 3.0719496084
MESH:D003924 Diabetes Mellitus, Type 2 Curcumin 10.5918403477
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 10.5920387270
MESH:D003924 Diabetes Mellitus, Type 2 Folic Acid 10.5916886840
MESH:D003924 Diabetes Mellitus, Type 2 Genistein 10.5916647724
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 10.5917107852
MESH:D003928 Diabetic Nephropathies Curcumin 15.9518204486
MESH:D003928 Diabetic Nephropathies Estradiol 15.9519279558
MESH:D003928 Diabetic Nephropathies Perindopril 15.9511427623
MESH:D003928 Diabetic Nephropathies Raloxifene 15.9517451421 17308373 15920148
MESH:D003929 Diabetic Neuropathies Progesterone 3.7217187935
MESH:D003930 Diabetic Retinopathy Sulindac 4.4212861449 17621415
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 22.4117562736 10915739 16485898 11287661 11834606 19085960 12958197 11739529 19164858 11743745 17522070 12705907 19370779 17906064 11421492 15968718 19923254 19739265 2444490 18071297 16393943 19416960 14986274 16781746 16227642 16109766 12594235 18713872 10774834 11461765 14550746 14725611 15619225 16081117 12153990 16177239 12392966 12540782 11529661 19420014 10663392
MESH:D056486 Drug-Induced Liver Injury Acetylcysteine 22.4111287661
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 22.413732212 19336974 7120509 16177239 6623471 2869522 15998439 19085960 3786805 15968718 15027814 7440962 10092053 16227642 21278145 11566570 10915739 4309450 6884620 17522070 7179309 9327722
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 22.4119107877
MESH:D056486 Drug-Induced Liver Injury Dimethylnitrosamine 22.418172417
MESH:D056486 Drug-Induced Liver Injury Drugs, Chinese Herbal 22.4115027814
MESH:D056486 Drug-Induced Liver Injury Ethanol 22.4111566570
MESH:D056486 Drug-Induced Liver Injury Silymarin 22.4114998559
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 22.4120420201
MESH:D056486 Drug-Induced Liver Injury Thioacetamide 22.4112963478
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 3.2919426721
MESH:D004362 Drug Toxicity Plant Preparations 6.4111033412
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 6.4111462148
MESH:D004381 Duodenal Ulcer Curcumin 3.3017351913
MESH:D050171 Dyslipidemias Dietary Fats 2.8418367378
MESH:D004421 Dystonia Phenobarbital 3.271851702
MESH:D004487 Edema imatinib 10.7719703484
MESH:D004487 Edema Raloxifene 10.7715860553
MESH:D004487 Edema Tetrachlorodibenzodioxin 10.7711000095 12711302
MESH:D004487 Edema Tetradecanoylphorbol Acetate 10.778113982 8273558 9599246 15177302 7812673 16716910 11698051
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 9.2615322242 18230668 16714409
MESH:D004489 Edema, Cardiac Tretinoin 9.2618230668
MESH:C536200 Ehlers-Danlos syndrome, cardiac valvular form marker/mechanism 15077201
OMIM:130060 EHLERS-DANLOS SYNDROME, TYPE VII, AUTOSOMAL DOMINANT marker/mechanism
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Calcitriol 15.7915138306
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 15.7912538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Progesterone 15.7917692515
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Raloxifene 15.7915845917
MESH:D004701 Endocrine Gland Neoplasms decitabine 4.3119294695
MESH:D004714 Endometrial Hyperplasia Diethylstilbestrol 9.2616402032
MESH:D004714 Endometrial Hyperplasia Genistein 9.2616402032
MESH:D016889 Endometrial Neoplasms Diethylstilbestrol 17.3516804899 15700306
MESH:D016889 Endometrial Neoplasms Estradiol 17.3519148513 11473722 18566989
MESH:D016889 Endometrial Neoplasms Folic Acid 17.3517301261
MESH:D016889 Endometrial Neoplasms Genistein 17.3511473722
MESH:D016889 Endometrial Neoplasms Tretinoin 17.3516569247
MESH:D004715 Endometriosis Progesterone 11.3016134523
MESH:D004715 Endometriosis Sulindac 11.3015652904
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 11.3010568697 9294722
MESH:D004831 Epilepsies, Myoclonic Phenobarbital 3.333659116
MESH:D004828 Epilepsies, Partial Phenobarbital 3.0711558140 3922381
MESH:D004827 Epilepsy Phenobarbital 2.4220417680
MESH:D004832 Epilepsy, Absence Phenobarbital 2.866401628
MESH:D017029 Epilepsy, Complex Partial Phenobarbital 3.487750514
MESH:D004830 Epilepsy, Tonic-Clonic Phenobarbital 3.233659116
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 4.3116302075
MESH:D004938 Esophageal Neoplasms arsenic trioxide 16.7312903497
MESH:D004938 Esophageal Neoplasms Dimethylnitrosamine 16.7317016578
MESH:D004938 Esophageal Neoplasms Ethanol 16.7316704527
MESH:D004938 Esophageal Neoplasms Paclitaxel 16.7316481741
MESH:D004938 Esophageal Neoplasms Plant Preparations 16.7316510608
MESH:D004938 Esophageal Neoplasms Sulindac 16.7312235107
MESH:D004938 Esophageal Neoplasms Zinc 16.7316543248
MESH:D017889 Exfoliation Syndrome Folic Acid 4.7016504073
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 6.7511564622
MESH:D005124 Eye Abnormalities Tretinoin 6.7516938888 9664655
MESH:D005218 Fat Necrosis Thioacetamide 4.9116456712
MESH:D005234 Fatty Liver arsenic trioxide 40.8015073043
MESH:D005234 Fatty Liver arsenite 40.8018296743
MESH:D005234 Fatty Liver Carbon Tetrachloride 40.8016239168 16045604 15959796 12795759 12631006 17595544 61145 19224547
MESH:D005234 Fatty Liver Curcumin 40.8019297423
MESH:D005234 Fatty Liver Dietary Fats 40.8017967931 19551842 18296743 19004024
MESH:D005234 Fatty Liver Diethylnitrosamine 40.8020387270 21071580
MESH:D005234 Fatty Liver Ethanol 40.8018620774 19236843 16409862
MESH:D005234 Fatty Liver Ethinyl Estradiol 40.8015345470
MESH:D005234 Fatty Liver Fish Oils 40.8018620774
MESH:D005234 Fatty Liver Raloxifene 40.8017473493
MESH:D005235 Fatty Liver, Alcoholic Ethanol 4.8517920746
MESH:D052776 Female Urogenital Diseases Diethylstilbestrol 3.1116002989 16513791 16611131 15751030 16534752
MESH:D005310 Fetal Alcohol Syndrome Ethanol 4.5015513904 16946407 10194807 15451040
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 2.6811858732
MESH:D018221 Fibromatosis, Abdominal Sulindac 4.6814745880
MESH:D018222 Fibromatosis, Aggressive imatinib 9.5517453242
MESH:D018222 Fibromatosis, Aggressive Sulindac 9.5519069698
MESH:D005355 Fibrosis arsenite 58.3418296743
MESH:D005355 Fibrosis baicalein 58.3419474275
MESH:D005355 Fibrosis baicalin 58.3419474275
MESH:D005355 Fibrosis Carbon Tetrachloride 58.3418705752
MESH:D005355 Fibrosis Curcumin 58.3418705752
MESH:D005355 Fibrosis Dietary Fats 58.3418296743
MESH:D005355 Fibrosis Emodin 58.3419474275
MESH:D005355 Fibrosis Quercetin 58.3419474275
MESH:D005355 Fibrosis salvianolic acid B 58.3419474275
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 58.3420067830
MESH:D005355 Fibrosis Tretinoin 58.3417994277
MESH:D005355 Fibrosis Trinitrobenzenesulfonic Acid 58.3417994277
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 3.5016904648
MESH:D005756 Gastritis Acetaminophen 20.7616983495
MESH:D005756 Gastritis Ethanol 20.7615046732
MESH:D005756 Gastritis Folic Acid 20.7617171786
MESH:D005756 Gastritis Zinc 20.7617241300
MESH:D005764 Gastroesophageal Reflux Sulindac 4.2511910360
MESH:D005770 Gastrointestinal Neoplasms Curcumin 3.9218462866
MESH:D005833 Genital Neoplasms, Female Diethylstilbestrol 10.1816452187
MESH:D005833 Genital Neoplasms, Female sodium arsenite 10.1816452187
MESH:D005871 Giant Lymph Node Hyperplasia Thalidomide 5.4912701121
MESH:D005901 Glaucoma Folic Acid 4.3416504073
MESH:D005909 Glioblastoma baicalein 16.2919804834
MESH:D005909 Glioblastoma Curcumin 16.2917596214
MESH:D005909 Glioblastoma Genistein 16.2916598420
MESH:D005909 Glioblastoma Quercetin 16.2919804834
MESH:D005909 Glioblastoma Tretinoin 16.2917312396
MESH:D005910 Glioma Quercetin 5.2117643826
MESH:D005910 Glioma Thalidomide 5.2116327979
MESH:D006042 Goiter perchlorate 4.5618801409
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 3.7810696789
MESH:D006130 Growth Disorders Zinc 3.4017217573
MESH:D006258 Head and Neck Neoplasms Curcumin 13.7518829502 18462866
MESH:D006258 Head and Neck Neoplasms decitabine 13.7519215824
MESH:D006258 Head and Neck Neoplasms Sirolimus 13.7519435901
MESH:D006258 Head and Neck Neoplasms Tretinoin 13.7516096774
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 4.3516084493
MESH:D006330 Heart Defects, Congenital Folic Acid 8.4017286298 16524890
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 8.4010048152 11294989
MESH:D006330 Heart Defects, Congenital Tretinoin 8.409664655 14991402
MESH:D006331 Heart Diseases Raloxifene 2.9511110106
MESH:D006333 Heart Failure Zinc 3.0817162251
MESH:D006335 Heart Injuries Zinc 4.9617074742
MESH:D006349 Heart Valve Diseases marker/mechanism 15077201
MESH:D016481 Helicobacter Infections Malondialdehyde 8.7417278206
MESH:D016481 Helicobacter Infections Zinc 8.7417241300
MESH:D006394 Hemangiosarcoma 2-nitrotoluene 4.3713678655
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 2.6111000095
MESH:D006501 Hepatic Encephalopathy Thioacetamide 3.8518665440 15929193 17276928
MESH:D006505 Hepatitis Carbon Tetrachloride 11.5519110552 19900420
MESH:D006505 Hepatitis Drugs, Chinese Herbal 11.5518339527
MESH:D006505 Hepatitis Thioacetamide 11.5516456712
MESH:D006527 Hepatolenticular Degeneration Zinc 3.9217276780
MESH:D006529 Hepatomegaly Phenobarbital 5.9016109766
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 5.9016120746 15340226 12621046
MESH:D015417 Hereditary Sensory and Motor Neuropathy Curcumin 4.2617701891
MESH:D006558 Herpes Genitalis Estradiol 4.2215709030
MESH:D006679 HIV Seropositivity Folic Acid 4.7017209195
MESH:D019247 HIV Wasting Syndrome testosterone enanthate 4.9417440010
MESH:D006689 Hodgkin Disease sodium arsenite 2.5012676792
MESH:D019584 Hot Flashes Estradiol 2.9517088409
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.248697196 16959395 15340226 18606429 16354765
MESH:D006930 Hyperalgesia Acetaminophen 9.3216870215
MESH:D006930 Hyperalgesia Ethanol 9.3218783367
MESH:D006930 Hyperalgesia Tretinoin 9.3216870215
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 3.7416899240
MESH:D006937 Hypercholesterolemia Curcumin 6.8518704882
MESH:D006937 Hypercholesterolemia Dietary Fats 6.8521332399
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 3.7916778211
MESH:D006943 Hyperglycemia Quercetin 3.3311834736 18262572
MESH:D020138 Hyperhomocysteinemia Folic Acid 3.8116395265 16397167 16433478 16865747 16755160
MESH:D006949 Hyperlipidemias Dietary Fats 7.1221332399
MESH:D006949 Hyperlipidemias Fish Oils 7.1215752949
MESH:D006965 Hyperplasia Diethylstilbestrol 8.7414722030 12960047
MESH:D006965 Hyperplasia halofuginone 8.7411874485
MESH:D006968 Hypersensitivity, Delayed Fish Oils 4.7011484837
MESH:D006973 Hypertension Perindopril 9.3011427623
MESH:D006973 Hypertension Quercetin 9.3018356687
MESH:D006973 Hypertension Raloxifene 9.3017577099 15787275
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 9.3018850075 18670907
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 3.3115338365
MESH:D006980 Hyperthyroidism Methimazole 4.8614678291
MESH:D006984 Hypertrophy Sirolimus 4.5119211884
MESH:D007021 Hypospadias Diethylstilbestrol 8.6716002989
MESH:D007021 Hypospadias Ethinyl Estradiol 8.6716569931 16945680
MESH:D007037 Hypothyroidism Methimazole 9.3818031379
MESH:D007037 Hypothyroidism Propylthiouracil 9.388137927 18031379
MESH:D020244 Infarction, Middle Cerebral Artery Progesterone 3.6315869954
MESH:D007246 Infertility Diethylstilbestrol 3.6015036965
MESH:D007247 Infertility, Female Ethinyl Estradiol 2.7312013081
MESH:D007248 Infertility, Male decitabine 7.8917581917
MESH:D007248 Infertility, Male Ethinyl Estradiol 7.8917937319
MESH:D007248 Infertility, Male sodium arsenite 7.8912646999 15346721
MESH:D007249 Inflammation Curcumin 27.1117151092 18403477 16956363
MESH:D007249 Inflammation Dietary Fats 27.1120412841
MESH:D007249 Inflammation Diethylnitrosamine 27.1118785209
MESH:D007249 Inflammation Flavonoids 27.1117296493
MESH:D007249 Inflammation Progesterone 27.1115869954
MESH:D007249 Inflammation Silymarin 27.1117213517
MESH:D007249 Inflammation Sulindac 27.113291741
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 27.1112878042 12200463
MESH:D007249 Inflammation Tetradecanoylphorbol Acetate 27.117812673 8273558 7562506 15177302 11698051
MESH:D007249 Inflammation Thalidomide 27.1116134734
MESH:D015212 Inflammatory Bowel Diseases Curcumin 5.3518596194 18200517
MESH:D015212 Inflammatory Bowel Diseases Trinitrobenzenesulfonic Acid 5.3518200517
MESH:D007251 Influenza, Human Quercetin 3.7016624496
MESH:D007333 Insulin Resistance Dietary Fats 5.4811836018 18457598
MESH:D007333 Insulin Resistance Estradiol 5.4816393666 16627594
MESH:D007410 Intestinal Diseases Tretinoin 7.4317994277
MESH:D007410 Intestinal Diseases Trinitrobenzenesulfonic Acid 7.4317994277
MESH:D007414 Intestinal Neoplasms Curcumin 7.7810783313
MESH:D007414 Intestinal Neoplasms Sulindac 7.7810223192 12351151 10213222 12584176 12663524 12628509
MESH:D007417 Intestinal Polyps Sulindac 4.2511245490 12394442
MESH:D007511 Ischemia Zinc 3.8616584753
MESH:D007569 Jaw Abnormalities Ethanol 13.0215513904
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 13.0216580747
MESH:D007569 Jaw Abnormalities Tretinoin 13.0215992940 17551590
MESH:D007627 Keloid Quercetin 4.1817086741
MESH:D017492 Keratosis, Seborrheic alitretinoin 4.8416144296
MESH:D007674 Kidney Diseases Acetaminophen 13.5615629191 12587719
MESH:D007674 Kidney Diseases Estradiol 13.5615618244
MESH:D007674 Kidney Diseases Quercetin 13.5616962696
MESH:D007674 Kidney Diseases sodium arsenite 13.5620008137
MESH:D007674 Kidney Diseases Zinc 13.5616960431
MESH:D007676 Kidney Failure, Chronic Malondialdehyde 8.4116518626
MESH:D007676 Kidney Failure, Chronic Zinc 8.4116518626
MESH:D007680 Kidney Neoplasms Diethylstilbestrol 5.3614681315 15003126 16762066
MESH:D007680 Kidney Neoplasms Estradiol 5.3615610895
MESH:D007683 Kidney Tubular Necrosis, Acute Calcium 4.2416316344
MESH:D007859 Learning Disorders Diethylstilbestrol 7.2317184923
MESH:D007859 Learning Disorders Ethanol 7.2315451040
MESH:D007889 Leiomyoma Curcumin 8.7018555241
MESH:D007889 Leiomyoma Raloxifene 8.7016973256
MESH:D007898 Leishmaniasis, Visceral Thalidomide 3.7216514283
MESH:D007938 Leukemia 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one 22.5612970779
MESH:D007938 Leukemia arsenic trioxide 22.5615070760
MESH:D007938 Leukemia Curcumin 22.5618462866
MESH:D007938 Leukemia decitabine 22.5618980019 19235587
MESH:D007938 Leukemia Genistein 22.5618980019 17468513
MESH:D007938 Leukemia Quercetin 22.5617468513
MESH:D007938 Leukemia Tretinoin 22.5617143497
MESH:D015451 Leukemia, Lymphocytic, Chronic, B-Cell Drugs, Chinese Herbal 3.5215802533
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 12.2512560223 17077332
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell Curcumin 12.2516106398
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell Emodin 12.2517077332
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 9.0916972261
MESH:D007948 Leukemia, Monocytic, Acute PD 98059 9.0916972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 6.8014633726
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive imatinib 6.8015748426 17301526 15107311 19208803
MESH:D007951 Leukemia, Myeloid arsenic trioxide 16.9919077051
MESH:D007951 Leukemia, Myeloid decitabine 16.9917236224 19117987 18454857
MESH:D007951 Leukemia, Myeloid imatinib 16.9917236224
MESH:D007951 Leukemia, Myeloid Tretinoin 16.9916932348 19285840 16482212
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 6.9216968895 17050201 20471514 19850784 16467208
MESH:D015470 Leukemia, Myeloid, Acute decitabine 6.9218704418 18460780 19387464 17679729 18206229 19010910
MESH:D015470 Leukemia, Myeloid, Acute Thalidomide 6.9218720364
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 6.9216294345 17596541 19850784
MESH:D015477 Leukemia, Myelomonocytic, Chronic decitabine 4.6518055864
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 5.7412018890 16891316 17217047 15622746 15336539 17649720 17107899 17712046 11468182 12679006 19642359 16823087 19035177 15213294 16112521 12712474 19225113 19075265 16966277 9834237 16330433 17869043 16331271 11161223 15748426
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 5.7416823087 12679006 17301526 17506722 19075265 16140955 19642359 17217047 16935935 16331271 17649720 16766008 19035177 17368321 17339181 9834237 19029980 15748426 16891316 17712046 17361223 17107899 16788101 17294898 19225113
MESH:D015458 Leukemia, T-Cell arsenic trioxide 9.1916882451
MESH:D015458 Leukemia, T-Cell Curcumin 9.1916106398
MESH:D017880 Limb Deformities, Congenital Ethanol 10.3317676605
MESH:D017880 Limb Deformities, Congenital Thalidomide 10.3310473037
MESH:D017880 Limb Deformities, Congenital Tretinoin 10.339224671
MESH:D008080 Liposarcoma Paclitaxel 4.0817353645
MESH:D008103 Liver Cirrhosis arsenite 37.0418296743
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 37.0417157831 11903743 16221502 16943688 16239168 17334410 21278145 17174718 11408273
MESH:D008103 Liver Cirrhosis Dietary Fats 37.0418296743
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 37.0418407596 20032147 19638242 18522880 18665156
MESH:D008103 Liver Cirrhosis Drugs, Chinese Herbal 37.0417163593
MESH:D008103 Liver Cirrhosis Ethanol 37.0415289165
MESH:D008103 Liver Cirrhosis halofuginone 37.0417180598
MESH:D008103 Liver Cirrhosis Phenobarbital 37.0421047994
MESH:D008103 Liver Cirrhosis Silymarin 37.0417213517
MESH:D008103 Liver Cirrhosis Thalidomide 37.0416943688 17174718
MESH:D008104 Liver Cirrhosis, Alcoholic Ethanol 4.3018295389
MESH:D008105 Liver Cirrhosis, Biliary Sulindac 3.6712468960
MESH:D008106 Liver Cirrhosis, Experimental 2-phenyl-4-(3-pyridin-2-yl-1H-pyrazol-4-yl)pyridine 50.1615723089
MESH:D008106 Liver Cirrhosis, Experimental baicalin 50.1618187930
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 50.1617900296 20821823 14716496 18210741 18420326 15057751 18472332 15362042 18395095 12741479 17976157 12546737 12609069 13678700 18263696 15673190 15052691 12898905 17823541 17565644 18277467 16192424 16033810 16116963 16011737 10355542 14716833 17557913 14748882 12632512 16097048 15996030 12666154 16027843 16136751 17525996 17869086 18317297 17481882 18156304 15338365 12445421 17805973 16248980 17714472 12667390 14512876 11481614 18251166 15730626 15370692 14724832 18376398 18412020 12649538 17944888 12445418 18395914 16015684 15123356 16638106 12958196 17708605 12632514 14620537 18339082 18006644 17640975 15925388 15893842 17698563 18205269 18472094 18279442 12389079 18166357 18054572 18418968 17922224 17766677 15931870 15650968 15818738 18187930 17761835 18705752 18481824 15876570 12586293 15959796 17631135 18429990 17721639
MESH:D008106 Liver Cirrhosis, Experimental Curcumin 50.1618006644 18705752 17355460
MESH:D008106 Liver Cirrhosis, Experimental Dimethylnitrosamine 50.1616627068 15138612 14643895 15733078 16603200 15067225 18629640 17640959 16009107 15842777 15723089 15942678 17719030 16042886 15571005 15099470 15744066 17196135 16169303 17036385 15383259 18210741 18239293 12918455 17432682 17465448 15081153 15479170 17198567 15492853 15504291 16270385 15577212 15298665 18364076 16544323 17724770 15339415 15591649 17666798 18095165 14709902 16570917 18672772 17203207 12925901 15369754 17348192 15793283 18371158 14568256 15366600 15763062 15864749 17201889 18637143 14726149 18237412 15161499 15086199 18567088 15798949 14659978 17881167 17534399
MESH:D008106 Liver Cirrhosis, Experimental Drugs, Chinese Herbal 50.1612632512 15849816 15818738 17666798 15864749 17036385 17881167 15763062 17348192 16610055 15641146 15383259 17629604 15754396 18567088 18606216 15339415 15744066 18371158 18237412
MESH:D008106 Liver Cirrhosis, Experimental Emodin 50.1615288473
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 50.1614716833 14659978
MESH:D008106 Liver Cirrhosis, Experimental Ethanol 50.1618166357
MESH:D008106 Liver Cirrhosis, Experimental Genistein 50.1617823541
MESH:D008106 Liver Cirrhosis, Experimental halofuginone 50.1612175628 18458672 16489207 11172339 14739098
MESH:D008106 Liver Cirrhosis, Experimental imatinib 50.1616596278
MESH:D008106 Liver Cirrhosis, Experimental Perindopril 50.1615619341 16872305 16596278 16097048
MESH:D008106 Liver Cirrhosis, Experimental Plant Preparations 50.1617724770
MESH:D008106 Liver Cirrhosis, Experimental Quercetin 50.1612741479
MESH:D008106 Liver Cirrhosis, Experimental S-Adenosylmethionine 50.1615983038
MESH:D008106 Liver Cirrhosis, Experimental salvianolic acid B 50.1616009107
MESH:D008106 Liver Cirrhosis, Experimental Silymarin 50.1618277467 17198567 15864749 15754394
MESH:D008106 Liver Cirrhosis, Experimental Sirolimus 50.1617050028
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 50.1612878042
MESH:D008106 Liver Cirrhosis, Experimental Thalidomide 50.1615465738
MESH:D008106 Liver Cirrhosis, Experimental Thioacetamide 50.1615716488 17355460 18416461 18380797 15362042 16126171 18458672 18032466 18615449 15078482 15334695 17292413 12679928 11682029 14739098 15288472 12175628 15316131 12557150 16343077 16097051 11172339 18606216 18295389 15288473 15095483 12531686 17050028 16098781 17629604 15075984 17127702 10677585 18395095 18031379 15474484 16248980 18263696 16489207 12085344 15158331 15465738 12891558 11481614 16511523
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 50.1618397230 16248980
MESH:D008107 Liver Diseases Acetaminophen 24.1316610002 16611625 19014921 12969438 12587719 19460945 19784758 11587558
MESH:D008107 Liver Diseases Carbon Tetrachloride 24.1315830285 15720792 17285989 16964402 16246199
MESH:D008107 Liver Diseases Curcumin 24.1316956363
MESH:D008107 Liver Diseases Diethylnitrosamine 24.1317034775
MESH:D008107 Liver Diseases Drugs, Chinese Herbal 24.1317207593
MESH:D008107 Liver Diseases Folic Acid 24.1316877991
MESH:D008107 Liver Diseases Phenobarbital 24.1319363144
MESH:D008107 Liver Diseases Silymarin 24.1317213517
MESH:D008107 Liver Diseases Sulindac 24.1316867024 14986274
MESH:D008107 Liver Diseases Thioacetamide 24.1315158337 18374380 16337175
MESH:D008108 Liver Diseases, Alcoholic Ethanol 9.2617207112 17347304
MESH:D008108 Liver Diseases, Alcoholic Silymarin 9.2617213517
MESH:D017093 Liver Failure Carbon Tetrachloride 3.3915123358
MESH:D017114 Liver Failure, Acute Acetaminophen 17.5216871587 17185352
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 17.5214706259 16899240
MESH:D017114 Liver Failure, Acute Dimethylnitrosamine 17.5217457977
MESH:D017114 Liver Failure, Acute Thioacetamide 17.5215633222 12479984 15313186 17276928
MESH:D008113 Liver Neoplasms arsenic trioxide 32.9514682389
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 32.9519294768
MESH:D008113 Liver Neoplasms Clofibric Acid 32.9517602206
MESH:D008113 Liver Neoplasms Diethylnitrosamine 32.9512112319 2422723 19499222 20118626 18648771 20405173 18754104 10737359 18977376 21071580 19294768 21167192 21278145 20501860 18644402 21047994 19812893 19833225 15175105 15885732 12771043 19996281 20137499 19642983 19254457 20583210 20452335 20434301 20101389 19551842 19638242 20492335 19427195 19256749 19690152 2862719 19426721 9163691 19073162 19255062 16942905 19850985 19090486 18978307
MESH:D008113 Liver Neoplasms Diethylstilbestrol 32.9515890375 16712894
MESH:D008113 Liver Neoplasms Dimethylnitrosamine 32.953113478 15890375
MESH:D008113 Liver Neoplasms Drugs, Chinese Herbal 32.9518339527
MESH:D008113 Liver Neoplasms Phenobarbital 32.9521047994 19812893 19482888 8742319 19073162 15975961
MESH:D008113 Liver Neoplasms Quercetin 32.9518980244
MESH:D008113 Liver Neoplasms Silymarin 32.9519168119
MESH:D008113 Liver Neoplasms sodium arsenite 32.9516712894 15276417
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 32.9516984957
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 19.8820377131
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 19.8815583823 12014681
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 19.8819009564 18308698 18775883 2563599 18544905 19519916 18079962 21159647 19126423 16267830 18164116 17942915 18253720 16842330 18282651 17854601 17174075 3124819 19539802 18093689 19004024 9362446
MESH:D008114 Liver Neoplasms, Experimental Dimethylnitrosamine 19.8815603536 6150874 1848544
MESH:D008114 Liver Neoplasms, Experimental Phenobarbital 19.8818308698 1399818 6150874 17172636 2563599
MESH:D008114 Liver Neoplasms, Experimental Quercetin 19.8819519916
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 19.8812151625
MESH:D008133 Long QT Syndrome arsenic trioxide 2.7215213294
MESH:D008171 Lung Diseases Acetylcysteine 12.9312815614
MESH:D008171 Lung Diseases Asbestos, Serpentine 12.9317200189
MESH:D008171 Lung Diseases Ozone 12.938266340 19066396
MESH:D008171 Lung Diseases sodium arsenite 12.9319095001
MESH:D055370 Lung Injury Ozone 3.0920417186
MESH:D008175 Lung Neoplasms Acetaldehyde 29.0217372256
MESH:D008175 Lung Neoplasms alitretinoin 29.0216413115
MESH:D008175 Lung Neoplasms arsenic trioxide 29.0211798837 19825857
MESH:D008175 Lung Neoplasms arsenite 29.0216809336
MESH:D008175 Lung Neoplasms Asbestos, Serpentine 29.0211198217
MESH:D008175 Lung Neoplasms Curcumin 29.0216243823 19359593 18462866
MESH:D008175 Lung Neoplasms Diethylnitrosamine 29.026695378 20970405 21163286 20512841
MESH:D008175 Lung Neoplasms Dimethylnitrosamine 29.0211884234 16061637 19555203
MESH:D008175 Lung Neoplasms Drugs, Chinese Herbal 29.0218339527
MESH:D008175 Lung Neoplasms Ozone 29.028597069 7614698
MESH:D008175 Lung Neoplasms Quercetin 29.0216280456
MESH:D008175 Lung Neoplasms sodium arsenite 29.0215276417 19931552 17306315 16712894 17077188
MESH:D008175 Lung Neoplasms Sulindac 29.0219359593 15713900
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 29.0211884234 19555203
MESH:D008175 Lung Neoplasms Tetradecanoylphorbol Acetate 29.0211807781
MESH:D008175 Lung Neoplasms vanadium pentoxide 29.0212376484
MESH:D008180 Lupus Erythematosus, Systemic Folic Acid 3.0517718048
MESH:D008181 Lupus Nephritis Diethylstilbestrol 4.3515166399
MESH:D008223 Lymphoma Curcumin 9.1518462866
MESH:D008223 Lymphoma decitabine 9.1519470736
MESH:D008223 Lymphoma Diethylstilbestrol 9.1515700306
MESH:D008228 Lymphoma, Non-Hodgkin Paclitaxel 3.4314749477
MESH:D016399 Lymphoma, T-Cell Curcumin 3.9216173963
MESH:D008275 Magnesium Deficiency Magnesium 5.6517823441
MESH:D052801 Male Urogenital Diseases Diethylstilbestrol 4.7116002989
MESH:D008325 Mammary Neoplasms, Experimental Drugs, Chinese Herbal 19.9614758024
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 19.9616891317 11807958 11408345 17203775
MESH:D008325 Mammary Neoplasms, Experimental Genistein 19.9614578162 12929590
MESH:D008325 Mammary Neoplasms, Experimental Progesterone 19.9617203775 11408345
MESH:D008325 Mammary Neoplasms, Experimental selenomethylselenocysteine 19.9615318939
MESH:D008325 Mammary Neoplasms, Experimental Tetradecanoylphorbol Acetate 19.968985016
MESH:D008325 Mammary Neoplasms, Experimental Zinc 19.9612773700
MESH:D020149 Manganese Poisoning Estradiol 3.6719453300
MESH:D019767 Maxillofacial Abnormalities Folic Acid 4.9016832597
MESH:D008527 Medulloblastoma Tretinoin 2.4017453147
MESH:D008545 Melanoma Curcumin 14.4918462866 17885582
MESH:D008545 Melanoma decitabine 14.4916505122 17785578
MESH:D008545 Melanoma Paclitaxel 14.4912025231 16342250 12040289
MESH:D008545 Melanoma Sirolimus 14.4919282848
MESH:D008545 Melanoma sodium arsenite 14.4919082730 16487513
MESH:D008545 Melanoma Sulindac 14.4916642371
MESH:D008545 Melanoma Thalidomide 14.4917089043 12829675 16098027
MESH:D008545 Melanoma Tretinoin 14.4916752155
MESH:D008546 Melanoma, Experimental Acetaminophen 2.7919513568
MESH:D008569 Memory Disorders Curcumin 7.2517263510
MESH:D008569 Memory Disorders Ethanol 7.2515451040 18411066
MESH:D008591 Meningomyelocele Tretinoin 3.6516940565
MESH:D001523 Mental Disorders Phosphates 4.2612686366
MESH:D008679 Metaplasia Ozone 4.3010496685
MESH:D008881 Migraine Disorders Magnesium 4.1818803445
MESH:D018200 Mixed Tumor, Mullerian Raloxifene 4.7415863610
MESH:D009062 Mouth Neoplasms Plant Preparations 7.3917418620
MESH:D009062 Mouth Neoplasms Sirolimus 7.3919435901
MESH:D009101 Multiple Myeloma arsenic trioxide 20.4811468182 19417148 14977855 15949261 19549372
MESH:D009101 Multiple Myeloma Curcumin 20.4819372569
MESH:D009101 Multiple Myeloma decitabine 20.4818172295
MESH:D009101 Multiple Myeloma Paclitaxel 20.4814749477
MESH:D009101 Multiple Myeloma Raloxifene 20.4816497877
MESH:D009101 Multiple Myeloma Thalidomide 20.4815741222 15920492 15939924 15867202 15744524 19372569 16445831 17168659 19112817 19112201
MESH:D019042 Muscle Neoplasms 2-nitrotoluene 5.8713678655
MESH:D009134 Muscular Atrophy, Spinal Curcumin 4.1217962980
MESH:D009145 Mushroom Poisoning Silymarin 6.1317213517
MESH:D009182 Mycosis Fungoides arsenic trioxide 3.8618349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 13.3616105982 16882451
MESH:D009190 Myelodysplastic Syndromes decitabine 13.3619157545 16882708 19010910 18608210
MESH:D009190 Myelodysplastic Syndromes Thalidomide 13.3618720364
MESH:D009190 Myelodysplastic Syndromes Tretinoin 13.3617596541
MESH:D009203 Myocardial Infarction Genistein 4.6217141266
MESH:D009203 Myocardial Infarction Quercetin 4.6219595682
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 2.3712213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 10.6016810080
MESH:D015428 Myocardial Reperfusion Injury Genistein 10.6017141266
MESH:D015428 Myocardial Reperfusion Injury Quercetin 10.6019207477
MESH:D020191 Myoclonic Epilepsies, Progressive Phenobarbital 3.6817484760
MESH:D009232 Myxoma Raloxifene 4.7416343187
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 7.8116624393
MESH:D009361 Neoplasm Invasiveness Curcumin 7.8118495463
MESH:D009362 Neoplasm Metastasis Acetylcysteine 10.4014720322
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 10.403581430 9029167
MESH:D009362 Neoplasm Metastasis imatinib 10.4015867366
MESH:D009362 Neoplasm Metastasis Paclitaxel 10.4015867366
MESH:D009369 Neoplasms alitretinoin 13.7516946489
MESH:D009369 Neoplasms decitabine 13.7517925555 19116145 19470736
MESH:D009369 Neoplasms Diethylstilbestrol 13.7515313581
MESH:D009369 Neoplasms Quercetin 13.7515185748
MESH:D009369 Neoplasms sodium arsenite 13.7511559025
MESH:D009369 Neoplasms Tretinoin 13.7516594593 16946489
MESH:D009374 Neoplasms, Experimental Asbestos, Serpentine 6.9911704859
MESH:D009374 Neoplasms, Experimental sodium arsenite 6.9920056578
MESH:D009376 Neoplasms, Hormone-Dependent Curcumin 8.7112497104
MESH:D009376 Neoplasms, Hormone-Dependent imatinib 8.7117614352
MESH:D009389 Neovascularization, Pathologic arsenite 7.5315738583
MESH:D009389 Neovascularization, Pathologic Estradiol 7.5317289903
MESH:D009421 Nervous System Malformations Diethylstilbestrol 28.5811399458
MESH:D009421 Nervous System Malformations Estradiol 28.5816427766 11399458
MESH:D009421 Nervous System Malformations Genistein 28.5816427766
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 28.5814600291
MESH:D009421 Nervous System Malformations Thalidomide 28.5816859833
MESH:D009421 Nervous System Malformations Tretinoin 28.589125849
MESH:D009423 Nervous System Neoplasms Curcumin 4.8218462866
MESH:D009436 Neural Tube Defects Acetylcysteine 16.7919446573
MESH:D009436 Neural Tube Defects arsenic trioxide 16.7910525206
MESH:D009436 Neural Tube Defects Folic Acid 16.7917438019
MESH:D009436 Neural Tube Defects sodium arsenite 16.7912854658
MESH:D009436 Neural Tube Defects Tretinoin 16.799142499
MESH:D019636 Neurodegenerative Diseases Acetaminophen 10.2618514411
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 10.2620387270
MESH:D019636 Neurodegenerative Diseases Sulindac 10.2617266991 16850258
MESH:D020078 Neurogenic Inflammation Quercetin 3.6217929310
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 4.3120387270
MESH:D009503 Neutropenia Folic Acid 3.7816322990
MESH:D009765 Obesity Curcumin 3.8519297423
MESH:D009765 Obesity Dietary Fats 3.8517217161 19632207 21332399 11836018 18457598 20132043 18674790 16723640 20518802
MESH:D009914 Oral Submucous Fibrosis marker/mechanism 16311067
MESH:C536042 Osteogenesis imperfecta, type 2A marker/mechanism
MESH:C536044 Osteogenesis imperfecta, type 3 marker/mechanism
MESH:C536045 Osteogenesis imperfecta, type 4 marker/mechanism
MESH:D010014 Osteolysis imatinib 9.7915867366
MESH:D010014 Osteolysis Paclitaxel 9.7915867366
MESH:D010018 Osteomalacia Phenobarbital 3.5717016548
MESH:D010024 Osteoporosis marker/mechanism
MESH:D010024 Osteoporosis Calcium 12.4817882678
MESH:D010024 Osteoporosis Curcumin 12.4818719352
MESH:D010024 Osteoporosis Genistein 12.4819401787
MESH:D010024 Osteoporosis Raloxifene 12.4817882678 15775268 19059307
MESH:D015663 Osteoporosis, Postmenopausal Drugs, Chinese Herbal 18.0416548355
MESH:D015663 Osteoporosis, Postmenopausal Genistein 18.0416169203
MESH:D015663 Osteoporosis, Postmenopausal Quercetin 18.0419495926
MESH:D015663 Osteoporosis, Postmenopausal Raloxifene 18.0415579764 17823083 15758505 17893378
MESH:D010051 Ovarian Neoplasms 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one 36.1216211241
MESH:D010051 Ovarian Neoplasms arsenic trioxide 36.1216624393 12452020 19769630
MESH:D010051 Ovarian Neoplasms Curcumin 36.1218462866 19020741
MESH:D010051 Ovarian Neoplasms decitabine 36.1219331143 19259094
MESH:D010051 Ovarian Neoplasms Estradiol 36.1219401270
MESH:D010051 Ovarian Neoplasms Genistein 36.1219005980
MESH:D010051 Ovarian Neoplasms Paclitaxel 36.1211161223
MESH:D010051 Ovarian Neoplasms Progesterone 36.1217393432 16525653
MESH:D010051 Ovarian Neoplasms Quercetin 36.1219005980
MESH:D010051 Ovarian Neoplasms sodium arsenite 36.1217306315 15276417
MESH:D010051 Ovarian Neoplasms Thalidomide 36.1216288038
MESH:D010051 Ovarian Neoplasms Tretinoin 36.1216936753
MESH:D010146 Pain Acetaminophen 7.5316870215
MESH:D010146 Pain Sulindac 7.533291741
MESH:D010146 Pain Tretinoin 7.5316870215
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 30.5015580305
MESH:D010190 Pancreatic Neoplasms Curcumin 30.5017440100 19401701 19196508
MESH:D010190 Pancreatic Neoplasms decitabine 30.5019294695
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 30.5016540662
MESH:D010190 Pancreatic Neoplasms Ethanol 30.5012384795
MESH:D010190 Pancreatic Neoplasms Phenobarbital 30.5016965848
MESH:D010190 Pancreatic Neoplasms Quercetin 30.5016965848
MESH:D010190 Pancreatic Neoplasms Sulindac 30.5016820089 11504793
MESH:D010190 Pancreatic Neoplasms Tetradecanoylphorbol Acetate 30.5015976015
MESH:D010190 Pancreatic Neoplasms Tretinoin 30.5015976015
MESH:D010195 Pancreatitis Trinitrobenzenesulfonic Acid 3.4817698068
MESH:D016584 Panic Disorder Ethinyl Estradiol 2.9511578682
MESH:D010212 Papilloma Tetradecanoylphorbol Acetate 3.538330346 18922899 18404319 12065085
MESH:D010235 Paraganglioma arsenic trioxide 3.4219927285
MESH:D010291 Paresis Thalidomide 5.499200351
MESH:D010300 Parkinson Disease Sirolimus 3.3919682553
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 3.4412520081
MESH:D010538 Peritonitis Ozone 3.3616369182
MESH:D010900 Pituitary Diseases Diethylstilbestrol 4.3614722030
MESH:D010911 Pituitary Neoplasms Diethylstilbestrol 3.8915687265 16977796
MESH:D010995 Pleural Diseases Asbestos, Serpentine 4.9210923243
MESH:D011014 Pneumonia Ozone 3.6018929643 18007984 18381685
MESH:D017499 Porokeratosis alitretinoin 5.1916144296
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 2.8018163543
MESH:D011230 Precancerous Conditions Diethylnitrosamine 11.422563599
MESH:D011230 Precancerous Conditions Phenobarbital 11.422563599
MESH:D011230 Precancerous Conditions Quercetin 11.4219056647
MESH:D054198 Precursor Cell Lymphoblastic Leukemia-Lymphoma imatinib 6.6112476293
MESH:D054198 Precursor Cell Lymphoblastic Leukemia-Lymphoma Thalidomide 6.6117031469
MESH:D011225 Pre-Eclampsia Zinc 3.5417114810
MESH:D011297 Prenatal Exposure Delayed Effects Diethylstilbestrol 6.9517184923
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 6.9511118676 11896295 11399792 11222880
MESH:D055728 Primary Myelofibrosis decitabine 3.9517616702
MESH:D011470 Prostatic Hyperplasia Calcitriol 3.9915572423
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 3.1620887781
MESH:D011471 Prostatic Neoplasms arsenic trioxide 4.8519131511
MESH:D011471 Prostatic Neoplasms baicalin 4.8515714805
MESH:D011471 Prostatic Neoplasms Calcitriol 4.8518247401 16644109 16289102 15754350 12479363
MESH:D011471 Prostatic Neoplasms Curcumin 4.8518156803 10851300 18769126 15129424 12497104 18226269 11398177
MESH:D011471 Prostatic Neoplasms Diethylstilbestrol 4.8515846301 17136230 15046698
MESH:D011471 Prostatic Neoplasms Estradiol 4.8516740699
MESH:D011471 Prostatic Neoplasms Genistein 4.8516925846 15256057 15378649
MESH:D011471 Prostatic Neoplasms Paclitaxel 4.8517136230 16729912 16356831 17172428
MESH:D011471 Prostatic Neoplasms Quercetin 4.8517292933 14715546
MESH:D011471 Prostatic Neoplasms Raloxifene 4.8516220300 16536755 15731164
MESH:D011471 Prostatic Neoplasms sodium arsenite 4.8516039940
MESH:D011471 Prostatic Neoplasms Thalidomide 4.8516729912
MESH:D011471 Prostatic Neoplasms Zinc 4.8512429649 16700911 16606632 16517595
MESH:D011507 Proteinuria Tretinoin 2.8716636307
MESH:D011536 Prurigo Thalidomide 5.4912755975
MESH:D011537 Pruritus Ethinyl Estradiol 2.5316919318 15861022
MESH:D019310 Pseudolymphoma Phenobarbital 3.6912752131
MESH:D011625 Pterygium Tretinoin 4.0016723453
MESH:D011656 Pulmonary Emphysema Curcumin 3.8219168576
MESH:D011658 Pulmonary Fibrosis Asbestos, Serpentine 5.2118569384 15511213
MESH:D011658 Pulmonary Fibrosis Drugs, Chinese Herbal 5.2116987627
MESH:D011693 Purpura Raloxifene 4.7415770314
MESH:D012003 Rectal Fistula Drugs, Chinese Herbal 5.1615043669
MESH:D051437 Renal Insufficiency Folic Acid 4.0115728788
MESH:D012128 Respiratory Distress Syndrome, Adult Acetylcysteine 7.0612210543
MESH:D012128 Respiratory Distress Syndrome, Adult Curcumin 7.0618379247 10666014
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.0818990726
MESH:D012162 Retinal Degeneration Zinc 3.5016584753
MESH:D012208 Rhabdomyosarcoma decitabine 8.4919155313
MESH:D012208 Rhabdomyosarcoma Tretinoin 8.4916116481 16283617
MESH:D012220 Rhinitis Acetaldehyde 4.0517050345
MESH:D012221 Rhinitis, Allergic, Perennial Drugs, Chinese Herbal 4.4715015336
MESH:D012468 Salivary Gland Neoplasms Progesterone 2.5018045962
MESH:D012509 Sarcoma Curcumin 3.4218462866
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 8.0816646077
MESH:D012512 Sarcoma, Ewing's Dactinomycin 8.0814601052
MESH:D012554 Schistosomiasis japonica Quercetin 4.7416862918
MESH:D012559 Schizophrenia Folic Acid 2.7616641680
MESH:D019873 Schnitzler Syndrome Thalidomide 5.1416096327
MESH:D012640 Seizures Ethanol 4.279754883
MESH:D012640 Seizures Phenobarbital 4.273137016 4039156 11442880 16876388
MESH:D003294 Seizures, Febrile Phenobarbital 4.036407741
MESH:D018805 Sepsis Curcumin 3.4118389075
MESH:D012871 Skin Diseases Folic Acid 4.6518709164
MESH:D012871 Skin Diseases halofuginone 4.6511874485
MESH:D012878 Skin Neoplasms sodium arsenite 13.1318572023 19524636
MESH:D012878 Skin Neoplasms tert-Butylhydroperoxide 13.138532709
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 13.1316192470
MESH:D012878 Skin Neoplasms Tetradecanoylphorbol Acetate 13.1318404319 8985016 8330346 12065085 11807781
MESH:D012878 Skin Neoplasms Tretinoin 13.1316467112
MESH:D013088 Spermatocele Diethylstilbestrol 9.0316002989 16709447
MESH:D013088 Spermatocele Ethinyl Estradiol 9.0316709447
MESH:D013118 Spinal Cord Diseases Folic Acid 4.7016361298
MESH:D013119 Spinal Cord Injuries Progesterone 3.4915862959 16503802
MESH:D016135 Spinal Dysraphism sodium arsenite 3.1512854658
MESH:D013158 Splenic Diseases Dimethylnitrosamine 4.4612587719
MESH:D013274 Stomach Neoplasms arsenic trioxide 14.3117007042
MESH:D013274 Stomach Neoplasms decitabine 14.3119037991
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 14.3118456281
MESH:D013274 Stomach Neoplasms Dimethylnitrosamine 14.3116033868
MESH:D013274 Stomach Neoplasms Drugs, Chinese Herbal 14.3118339527
MESH:D013274 Stomach Neoplasms Ethanol 14.3118456281
MESH:D013274 Stomach Neoplasms Folic Acid 14.3117171786
MESH:D013274 Stomach Neoplasms imatinib 14.3115786421
MESH:D013274 Stomach Neoplasms Paclitaxel 14.3118506536 18396642
MESH:D013274 Stomach Neoplasms Tretinoin 14.3117261132
MESH:D013276 Stomach Ulcer Acetylcysteine 11.4917918041
MESH:D013276 Stomach Ulcer Curcumin 11.4919188055 16631530
MESH:D013276 Stomach Ulcer Ethanol 11.499211565 9562338 16755016 17189318 17918041 11906479
MESH:D013276 Stomach Ulcer Thalidomide 11.4915138204
MESH:D020521 Stroke Folic Acid 6.8416517955
MESH:D020521 Stroke Raloxifene 6.8416837676
MESH:D013345 Subarachnoid Hemorrhage Drugs, Chinese Herbal 4.9517634840
MESH:D013375 Substance Withdrawal Syndrome Ethanol 3.559754883
MESH:D024801 Tauopathies Paclitaxel 4.0216930453
MESH:D019851 Thrombophilia Ethinyl Estradiol 2.8811994571
MESH:D013927 Thrombosis Ethinyl Estradiol 2.4715669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.0912697716
MESH:D013964 Thyroid Neoplasms arsenic trioxide 24.1819014326
MESH:D013964 Thyroid Neoplasms decitabine 24.1817967635
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 24.187505956
MESH:D013964 Thyroid Neoplasms imatinib 24.1816940797
MESH:D013964 Thyroid Neoplasms Phenobarbital 24.181399818
MESH:D013964 Thyroid Neoplasms Propylthiouracil 24.1815710170
MESH:D013964 Thyroid Neoplasms Tretinoin 24.1816026305 17045167
MESH:D013978 Tibial Fractures Estradiol 11.0319048282
MESH:D013978 Tibial Fractures Raloxifene 11.0319048282
MESH:D014062 Tongue Neoplasms Tretinoin 7.6416051514
MESH:D014062 Tongue Neoplasms Zinc 7.6416543248
MESH:D016171 Torsades de Pointes arsenic trioxide 3.1715213294
MESH:D014376 Tuberculosis Tretinoin 2.6816040207
MESH:D014402 Tuberous Sclerosis Sirolimus 4.8118495876 21115397
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 21.5212845720 11780464 12973940 20435036
MESH:D001749 Urinary Bladder Neoplasms Curcumin 21.5218593936
MESH:D001749 Urinary Bladder Neoplasms decitabine 21.5219087683 17616700
MESH:D001749 Urinary Bladder Neoplasms Diethylstilbestrol 21.5217306315 16712894 16452187
MESH:D001749 Urinary Bladder Neoplasms Plant Preparations 21.5211251952
MESH:D001749 Urinary Bladder Neoplasms Quercetin 21.5216720314
MESH:D001749 Urinary Bladder Neoplasms Raloxifene 21.5217572228
MESH:D001749 Urinary Bladder Neoplasms sodium arsenite 21.5216712894 16452187 17306315 11723127
MESH:D014565 Urogenital Neoplasms Curcumin 4.4718462866
MESH:D014581 Urticaria Acetaminophen 2.2510982225
MESH:D002583 Uterine Cervical Neoplasms Diethylstilbestrol 11.8316175088
MESH:D002583 Uterine Cervical Neoplasms sodium arsenite 11.8311813266
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 11.8316129372
MESH:D014591 Uterine Diseases Diethylstilbestrol 4.3614652134
MESH:D014594 Uterine Neoplasms Diethylstilbestrol 11.7816690809 15809267
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 11.7814692618
MESH:D014594 Uterine Neoplasms Sulindac 11.7818645019
MESH:D014604 Uveal Neoplasms decitabine 10.1517785578
MESH:D014604 Uveal Neoplasms Tretinoin 10.1516752155
MESH:D014605 Uveitis Sirolimus 4.821336536
MESH:D014625 Vaginal Neoplasms Diethylstilbestrol 3.6616513791 16002989
MESH:D014652 Vascular Diseases sodium arsenite 9.4917056641
MESH:D014652 Vascular Diseases Thalidomide 9.4915741222
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 3.7812125929
MESH:D054556 Venous Thromboembolism Raloxifene 4.4016837676
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 2.8215869587 14671159
MESH:D014820 Vitiligo Tretinoin 3.3016761959
MESH:D014846 Vulvar Neoplasms Raloxifene 4.7416343187
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 3.4415886252
MESH:D015430 Weight Gain Dietary Fats 3.0516723640
MESH:D009396 Wilms Tumor Tretinoin 3.2816287080
MESH:D014947 Wounds and Injuries Drugs, Chinese Herbal 3.8816313111
Pathway ID Pathway Name
KEGG:05146 Amoebiasis
REACT:18266 Axon guidance
KEGG:04512 ECM-receptor interaction
KEGG:04510 Focal adhesion
REACT:604 Hemostasis
REACT:13552 Integrin cell surface interactions
KEGG:04974 Protein digestion and absorption
REACT:16888 Signaling by PDGF
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA35042
    • No data
    Releated disease ID Related disease Name
    PA445180Osteogenesis Imperfecta
    Releated drug ID Related drug Name
    PA450952phospholipids
    PA451620teriparatide
    Drug Bank Top
    Drugbank ID Action Drug Name Description
    DB00048 - Collagenase Anti-Ulcer Agents;Topical
    No data
    No data
    No data

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


    Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved