AutismKB 2.0

Annotation Detail for SPATA17


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Basic Information Top
Gene Symbol:SPATA17 ( IQCH,MSRG-11,MSRG11,RP11-144C20.1 )
Gene Full Name: spermatogenesis associated 17
Band: 1q41
Quick LinksEntrez ID:128153; OMIM: 611032; Uniprot ID:SPT17_HUMAN; ENSEMBL ID: ENSG00000162814; HGNC ID: 25184
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
No data
No data
Desease Name
PSYCH
anorexia nervosa
No data
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000082 Acetaminophen Acetaminophen affects the expression of SPATA17 mRNAaffects expression 17562736
D000638 Amiodarone Amiodarone results in increased expression of SPATA17 mRNAincreases expression 19774075
D016572 Cyclosporine Cyclosporine results in increased expression of SPATA17 mRNAincreases expression 20106945
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000799 Angioedema Acetaminophen 4.7110982225
MESH:D001145 Arrhythmias, Cardiac Amiodarone 4.2518057881 18218290 20041841
MESH:D001281 Atrial Fibrillation Amiodarone 4.2318651412 19698954
MESH:D001321 Autistic Disorder Acetaminophen 1.3918445737
MESH:D001778 Blood Coagulation Disorders Amiodarone 4.3819483382
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 1.413084413
MESH:D002311 Cardiomyopathy, Dilated Amiodarone 3.0119225199 15710769
MESH:D002341 Carotid Artery Thrombosis Amiodarone 5.8318974383
MESH:D002386 Cataract Acetaminophen 2.8110977129
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 2.8212371664
MESH:D002779 Cholestasis Cyclosporine 3.2419486331
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 4.2112540782 16177239 16781746 10774834 11287661 19085960 11739529 16485898 11834606 16109766 11743745 16081117 10915739 12153990 14725611 15619225 11529661 18713872 16227642 16393943 12705907 10663392 19739265 12958197 17906064 15968718 11461765 2444490 14550746 19923254 19416960 12392966 14986274 19370779 18071297 11421492 17522070 19420014 12594235 17562736 19164858
MESH:D056486 Drug-Induced Liver Injury Amiodarone 4.2118218290 15265979
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.9619426721
MESH:D005234 Fatty Liver Amiodarone 9.4914986274
MESH:D005234 Fatty Liver Cyclosporine 9.4919224547
MESH:D005355 Fibrosis Cyclosporine 3.7912168785 12639820
MESH:D005756 Gastritis Acetaminophen 4.5416983495
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.968708960
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 5.1615720958
MESH:D006529 Hepatomegaly Amiodarone 4.4015265979
MESH:D006930 Hyperalgesia Acetaminophen 3.0616870215
MESH:D006937 Hypercholesterolemia Amiodarone 4.368137927 9751232
MESH:D006973 Hypertension Cyclosporine 2.2310903974
MESH:D007037 Hypothyroidism Amiodarone 5.1718020914 17991464
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 5.3115604871
MESH:D007674 Kidney Diseases Acetaminophen 6.5515629191 12587719
MESH:D007674 Kidney Diseases Cyclosporine 6.558314463 10903974 18776723
MESH:D007680 Kidney Neoplasms Cyclosporine 3.1212371664
MESH:D008064 Lipidoses Amiodarone 3.8215342952 17567588
MESH:D008107 Liver Diseases Acetaminophen 1.7119784758 16611625 19014921 12969438 19460945 16610002 12587719 11587558
MESH:D017114 Liver Failure, Acute Acetaminophen 3.6816871587 17185352
MESH:D008133 Long QT Syndrome Amiodarone 3.9215350150 11989578 17391786
MESH:D008171 Lung Diseases Amiodarone 3.6512587719
MESH:D017563 Lung Diseases, Interstitial Amiodarone 5.3418516814
MESH:D008546 Melanoma, Experimental Acetaminophen 4.2219513568
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 5.6516801185
MESH:D009181 Mycoses Amiodarone 5.7712754197 17974566
MESH:D009402 Nephrosis, Lipoid Cyclosporine 5.3117954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.7019348381 18481113
MESH:D019636 Neurodegenerative Diseases Acetaminophen 3.2618514411
MESH:D010146 Pain Acetaminophen 2.7716870215
MESH:D011230 Precancerous Conditions Cyclosporine 3.6412371664
MESH:D011565 Psoriasis Cyclosporine 2.3416882103
MESH:D011658 Pulmonary Fibrosis Amiodarone 2.9812832656 12490602 11597910
OMIM:609620 SHORT QT SYNDROME 1 Amiodarone 5.8318724381
MESH:D013276 Stomach Ulcer Amiodarone 3.7918087811
MESH:D013610 Tachycardia Amiodarone 4.8711238279
MESH:D017180 Tachycardia, Ventricular Amiodarone 4.7719225199
MESH:D013959 Thyroid Diseases Amiodarone 5.6219731979
MESH:D013971 Thyrotoxicosis Amiodarone 5.5118020914 19584973
MESH:D016171 Torsades de Pointes Amiodarone 4.9311989578 17467628
MESH:D014581 Urticaria Acetaminophen 3.5010982225
MESH:D014605 Uveitis Cyclosporine 4.851336536
MESH:D014985 Xerophthalmia Cyclosporine 5.3117120751
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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