AutismKB 2.0

Annotation Detail for COL4A1


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Basic Information Top
Gene Symbol:COL4A1 ( arresten )
Gene Full Name: collagen, type IV, alpha 1
Band: 13q34
Quick LinksEntrez ID:1282; OMIM: 120130; Uniprot ID:CO4A1_HUMAN; ENSEMBL ID: ENSG00000187498; HGNC ID: 2202
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa05146Amoebiasis
hsa04974Protein digestion and absorption
hsa05222Small cell lung cancer
hsa04512ECM-receptor interaction
hsa04510Focal adhesion
hsa05200Pathways in cancer
Pathway IDPathway Name
Axon guidance
Signaling by PDGF
Integrin cell surface interactions
No data
Pathway IDPathway Name
P00034Integrin signalling pathway
No data
Related Diseases/Disorders Top
No data
No data
Desease Name
periodontitis
CARDIOVASCULAR
IMMUNE
arterial stiffness
Desease Name
Arterial stiffness
Desease Name
Brain small vessel disease with hemorrhage
Angiopathy, hereditary, with nephropathy, aneurysms, and muscle cramps
Porencephaly
Brain small vessel disease with Axenfeld-Rieger anomaly
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000079 Acetaldehyde Acetaldehyde results in decreased expression of COL4A1 mRNAdecreases expression 8135774
D000079 Acetaldehyde Acetaldehyde results in decreased expression of COL4A1 proteindecreases expression 8135774
D000079 Acetaldehyde TGFB1 protein inhibits the reaction [Acetaldehyde results in decreased expression of COL4A1 protein]decreases expression|decreases reaction 8135774
D000082 Acetaminophen Acetaminophen affects the expression of COL4A1 mRNAaffects expression 17562736
D000082 Acetaminophen Acetaminophen results in increased expression of COL4A1 mRNAincreases expression 11264010
19420014
D000111 Acetylcysteine Acetylcysteine results in decreased expression of COL4A1 mRNAdecreases expression 16084531
D000643 Ammonium Chloride Ammonium Chloride affects the expression of COL4A1 mRNAaffects expression 16483693
C004984 apocarotenal apocarotenal results in decreased expression of COL4A1 mRNAdecreases expression 17034753
C061004 benidipine benidipine affects the expression of COL4A1 mRNAaffects expression 15721868
D019324 beta-Naphthoflavone [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of COL4A1 mRNAaffects cotreatment|increases expression 18164116
D019207 beta Carotene beta Carotene results in decreased expression of COL4A1 mRNAdecreases expression 17034753
D020122 tert-Butylhydroperoxide tert-Butylhydroperoxide results in decreased expression of COL4A1 mRNAdecreases expression 15336504
C459604 candoxin candoxin results in decreased expression of COL4A1 mRNAdecreases expression 16309724
D002995 Clofibric Acid Clofibric Acid affects the expression of COL4A1 mRNAaffects expression 17602206
D003474 Curcumin Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of COL4A1 mRNA]decreases reaction|increases expression 18200517
D016572 Cyclosporine Cyclosporine results in decreased expression of COL4A1 mRNAdecreases expression 20106945
D003907 Dexamethasone [Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of COL4A1 mRNAaffects cotreatment|increases expression 16054899
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of COL4A1 mRNAaffects cotreatment|increases expression 18164116
D004052 Diethylnitrosamine Diethylnitrosamine results in increased expression of COL4A1 mRNAincreases expression 19638242
C045651 epigallocatechin gallate epigallocatechin gallate results in decreased expression of COL4A1 mRNAdecreases expression 16084531
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of COL4A1 mRNAaffects expression 17555576
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of COL4A1 mRNAincreases expression 17942748
14976129
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of COL4A1 mRNAaffects cotreatment|increases expression 17942748
D005038 Ethylnitrosourea Ethylnitrosourea results in increased mutagenesis of COL4A1 geneincreases mutagenesis 16724327
C031927 hydroquinone hydroquinone results in decreased expression of COL4A1 mRNAdecreases expression 18055817
C031927 hydroquinone hydroquinone results in increased expression of COL4A1 proteinincreases expression 18055817
C031927 hydroquinone MMP14 protein inhibits the reaction [hydroquinone results in increased expression of COL4A1 protein]decreases reaction|increases expression 18055817
C031927 hydroquinone [TIMP2 protein co-treated with MMP14 protein] inhibits the reaction [hydroquinone results in increased expression of COL4A1 protein]affects cotreatment|decreases reaction|increases expression 18055817
C031927 hydroquinone TIMP2 protein inhibits the reaction [hydroquinone results in increased expression of COL4A1 protein]decreases reaction|increases expression 18055817
D015056 1-Methyl-3-isobutylxanthine [Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of COL4A1 mRNAaffects cotreatment|increases expression 16054899
D007657 Ketone Bodies Ketone Bodies results in decreased expression of COL4A1 mRNAdecreases expression 16807920
C013592 mangiferin mangiferin inhibits the reaction [AGT protein results in increased expression of COL4A1 mRNA]decreases reaction|increases expression 19706694
D017239 Paclitaxel Paclitaxel results in increased expression of COL4A1 mRNAincreases expression 19682730
C006253 pirinixic acid pirinixic acid results in increased expression of COL4A1 mRNAincreases expression 18445702
D010936 Plant Extracts Plant Extracts inhibits the reaction [AGT protein results in increased expression of COL4A1 mRNA]decreases reaction|increases expression 19706694
D011374 Progesterone Progesterone results in decreased expression of COL4A1 mRNAdecreases expression 18070364
C089730 rosiglitazone [Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of COL4A1 mRNAaffects cotreatment|increases expression 16054899
C017947 sodium arsenite sodium arsenite results in decreased expression of COL4A1 mRNAdecreases expression 18812580
D013629 Tamoxifen Tamoxifen affects the expression of COL4A1 mRNAaffects expression 17555576
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of COL4A1 mRNAaffects cotreatment|increases expression 17942748
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of COL4A1 mRNAincreases expression 15328365
D013853 Thioacetamide HGF protein inhibits the reaction [Thioacetamide results in increased expression of COL4A1 mRNA]decreases reaction|increases expression 10677585
D013853 Thioacetamide Thioacetamide results in increased expression of COL4A1 mRNAincreases expression 10677585
D014212 Tretinoin Tretinoin results in increased expression of COL4A1 mRNAincreases expression 16604517
D014212 Tretinoin Tretinoin results in increased expression of COL4A1 mRNAincreases expression 17303670
D014302 Trinitrobenzenesulfonic Acid Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of COL4A1 mRNA]decreases reaction|increases expression 18200517
D014302 Trinitrobenzenesulfonic Acid Trinitrobenzenesulfonic Acid results in increased expression of COL4A1 mRNAincreases expression 18200517
17982090
C025643 vinclozolin vinclozolin affects the expression of COL4A1 mRNAaffects expression 19015723
D002762 Cholecalciferol Cholecalciferol results in increased expression of COL4A1 mRNAincreases expression 17170073
D014810 Vitamin E Vitamin E results in increased expression of COL4A1 mRNAincreases expression 19244175
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 4.1714745880
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 2.4914514962 15322242 11752688
MESH:D000138 Acidosis Ammonium Chloride 3.1918287403
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.5717505938
MESH:D055371 Acute Lung Injury pirinixic acid 2.7818653653
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 1.7214692618
MESH:D000236 Adenoma beta-Naphthoflavone 10.0919389873
MESH:D000236 Adenoma Diethylnitrosamine 10.0910737359 6695378
MESH:D000236 Adenoma Ethylnitrosourea 10.096695378
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 15.1417162532 19061943 16434500 17620307 18056438 19052882
MESH:D018248 Adenoma, Liver Cell pirinixic acid 15.1416434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 15.1416835633
MESH:D000310 Adrenal Gland Neoplasms sodium arsenite 4.3215276417
MESH:D018246 Adrenocortical Adenoma sodium arsenite 4.5317306315 16712894
MESH:D019973 Alcohol-Related Disorders Curcumin 4.7117887948
MESH:D000505 Alopecia Tretinoin 3.3315955085
MESH:D000544 Alzheimer Disease Curcumin 6.2915590663
MESH:D000544 Alzheimer Disease Plant Extracts 6.2916962711
MESH:D000544 Alzheimer Disease rosiglitazone 6.2919621015
MESH:D000707 Anaphylaxis mangiferin 5.1114669257 16536907
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.6311748828
MESH:D000799 Angioedema Acetaminophen 3.4710982225
OMIM:611773 ANGIOPATHY, HEREDITARY, WITH NEPHROPATHY, ANEURYSMS, AND MUSCLE CRAMPS marker/mechanism
MESH:D001008 Anxiety Disorders vinclozolin 3.3519015723
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.1111256880
MESH:D001169 Arthritis, Experimental Dexamethasone 15.6817659584
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 15.6815885639
MESH:D001169 Arthritis, Experimental Plant Extracts 15.6814686799
MESH:D001169 Arthritis, Experimental Tretinoin 15.6816412693
MESH:D001172 Arthritis, Rheumatoid Curcumin 4.4116807698
MESH:D001172 Arthritis, Rheumatoid Tretinoin 4.4116292516
MESH:D001249 Asthma Acetaldehyde 7.469600491
MESH:D001249 Asthma epigallocatechin gallate 7.4616516891
MESH:D001249 Asthma Tretinoin 7.4616456186
MESH:D050197 Atherosclerosis Curcumin 6.4818704882
MESH:D050197 Atherosclerosis mangiferin 6.4818450471
MESH:D001321 Autistic Disorder Acetaminophen 1.4618445737
MESH:D001327 Autoimmune Diseases Cholecalciferol 16.1816142846
MESH:D001327 Autoimmune Diseases Curcumin 16.1819761891
MESH:D001327 Autoimmune Diseases epigallocatechin gallate 16.1819761891
MESH:D001471 Barrett Esophagus Tretinoin 4.0516935849
MESH:D001778 Blood Coagulation Disorders pirinixic acid 19.2719483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 19.2712125929
MESH:D001778 Blood Coagulation Disorders Thioacetamide 19.2719483382
MESH:D001778 Blood Coagulation Disorders Tretinoin 19.2716197459 16206674
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.4215340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.5315746008
MESH:D001859 Bone Neoplasms Paclitaxel 4.2315867366
MESH:D001862 Bone Resorption mangiferin 4.599881647
MESH:D001927 Brain Diseases Ethylnitrosourea 4.5614991843
MESH:D020201 Brain Hemorrhage, Traumatic Progesterone 4.9617868700
MESH:D001930 Brain Injuries Progesterone 3.9015845082 15380490 15665606
MESH:D002545 Brain Ischemia beta Carotene 15.1216157235
MESH:D002545 Brain Ischemia Curcumin 15.1216770732
MESH:D002545 Brain Ischemia Plant Extracts 15.1216041641
MESH:D001932 Brain Neoplasms Curcumin 8.0917596214
MESH:D001932 Brain Neoplasms Ethylnitrosourea 8.0915144691 16357521 18412241 16436596 16651633
OMIM:607595 BRAIN SMALL VESSEL DISEASE WITH HEMORRHAGE marker/mechanism
MESH:D001943 Breast Neoplasms Curcumin 3.5019250217 18593918 16243823 18462866
MESH:D001943 Breast Neoplasms Diethylnitrosamine 3.5017474063
MESH:D001943 Breast Neoplasms Paclitaxel 3.5016244791 16115903 16273361 11325840 18234424 15136595 18223236 18323546
MESH:D001943 Breast Neoplasms Progesterone 3.5017614352 15562024 16175315
MESH:D001943 Breast Neoplasms Tamoxifen 3.5015668708 19103187 17049068 19200415 19221464 17261762 18815881 21152245 19487384 20390343 17440819 19244106 19410462 18984771 16202921 20005174 20544844 19059307 19189210 20859285 19115204 19288272 17893378 16273361 19011961 18997820 18855134 16818667 21138602 18821012 18351453 19155303 16873071 18629630 19189212 11161223 19084267 20135344 15565566 19289846 19142967 18425577 20065188 19066611 17242785
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 3.5020435547
MESH:D001943 Breast Neoplasms Tretinoin 3.5016443354 16166294 16873071
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 4.2216813970
MESH:D002057 Burns, Chemical Plant Extracts 4.969625245
MESH:D002252 Carbon Tetrachloride Poisoning Vitamin E 3.5716050911
MESH:D002277 Carcinoma Curcumin 7.3318593918
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 7.3316835633
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 4.1519066611
MESH:D018236 Carcinoma, Embryonal Tretinoin 4.7816168501
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 15.723084413
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 15.7211831363 16807293 19822196 19107877 18506893 20084675 16779866 18978308 20524982 3581430 17173139 18665156 17978847 18691550 20007298 17428255 21159647 18971187 17138121 19418558 16288022 10672840 19171122 16681979 16569478 20935162 20727157 18788625 17055752 18785209 16328049 16540662 16502159 20432363 19208518 19383236 3084413 16878318 17761372 19919837 19539802 18056438 19701751 20514400 18210153 19519916 20214788 17162532 16935385 16830150 19052882 16698587 18393292 10737359 20101231 19394651 20512989 19335982 18494052
MESH:D006528 Carcinoma, Hepatocellular Paclitaxel 15.7216313753
MESH:D006528 Carcinoma, Hepatocellular Plant Extracts 15.7218834353
MESH:D006528 Carcinoma, Hepatocellular sodium arsenite 15.7215276417 17306315 16507464
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 15.7216924424
MESH:D006528 Carcinoma, Hepatocellular Thioacetamide 15.7217997003
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 15.721917145
MESH:D002289 Carcinoma, Non-Small-Cell Lung Curcumin 2.8518414057
MESH:D002294 Carcinoma, Squamous Cell Acetylcysteine 9.8917015178
MESH:D002294 Carcinoma, Squamous Cell Curcumin 9.8918462866
MESH:D002294 Carcinoma, Squamous Cell sodium arsenite 9.8918572023
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 9.8916051514 16096774
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 3.3017572228
MESH:D006332 Cardiomegaly Plant Extracts 6.2917645561
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 6.2918670907 16120746 18850075
MESH:D002310 Cardiomyopathy, Alcoholic Acetaldehyde 6.1010525098
MESH:D002386 Cataract Acetaminophen 6.5010977129
MESH:D002386 Cataract Tretinoin 6.5017460283
MESH:D002471 Cell Transformation, Neoplastic Acetylcysteine 18.4318226522
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 18.4312371664
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 18.4321159647 17174075 7505956 2727394
MESH:D002471 Cell Transformation, Neoplastic Ethylnitrosourea 18.4316003739
MESH:D002471 Cell Transformation, Neoplastic sodium arsenite 18.4320056578 19524636
MESH:D016543 Central Nervous System Neoplasms Ethylnitrosourea 5.6117160924
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 4.2216129372
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 14.3419052882
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 14.3416835633
MESH:D018281 Cholangiocarcinoma Thioacetamide 14.3418291259
MESH:D002779 Cholestasis Cyclosporine 11.7719486331
MESH:D002779 Cholestasis Ethinyl Estradiol 11.7716105132 11677210 17681005 17333356 16919318 17110522 15861022
MESH:D002779 Cholestasis pirinixic acid 11.7719176532
MESH:D002822 Choriocarcinoma Tretinoin 4.7816461808
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 5.2312621046 15340226 15668235 16354765 8697196
MESH:D002972 Cleft Palate Tretinoin 5.239407595
MESH:D003092 Colitis Curcumin 14.0718200517 16804969 16782535
MESH:D003092 Colitis Tretinoin 14.0717035595
MESH:D003092 Colitis Trinitrobenzenesulfonic Acid 14.0718023891 18200517 16867261 11698051 17936198 16804969 17991707 16782535 16474422
MESH:D003093 Colitis, Ulcerative Trinitrobenzenesulfonic Acid 3.3117276891
MESH:D003103 Coloboma Curcumin 4.2218809619
MESH:D003110 Colonic Neoplasms Curcumin 3.7719359593 16340194
MESH:D003110 Colonic Neoplasms Dexamethasone 3.7715824018
MESH:D015179 Colorectal Neoplasms Paclitaxel 2.4418802399
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 2.7514669216 17141729
MESH:D016510 Corneal Neovascularization Curcumin 4.5418497527
MESH:D019465 Craniofacial Abnormalities Dexamethasone 5.0317728286
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 5.0310048152 15322242 20055451
MESH:D019465 Craniofacial Abnormalities Tretinoin 5.039664655 10589399 9125849 17551590 9211117 16925845 9224671 14991402 9142499 8800419
MESH:D019465 Craniofacial Abnormalities Vitamin E 5.0319769572
MESH:D003456 Cryptorchidism vinclozolin 3.9914966744
MESH:D003457 Cryptosporidiosis mangiferin 5.4816547730
MESH:D003550 Cystic Fibrosis Acetylcysteine 4.0619747007
MESH:D003711 Demyelinating Diseases Tamoxifen 4.0019031437
MESH:D017449 Dermatitis, Allergic Contact Dexamethasone 3.0712438553
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.2518249437
MESH:D003920 Diabetes Mellitus rosiglitazone 3.9917446233
MESH:D003921 Diabetes Mellitus, Experimental mangiferin 4.3019028559 12093613
MESH:D003924 Diabetes Mellitus, Type 2 benidipine 19.4416387788
MESH:D003924 Diabetes Mellitus, Type 2 Curcumin 19.4418403477
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 19.4420387270
MESH:D003924 Diabetes Mellitus, Type 2 epigallocatechin gallate 19.4416988119
MESH:D003924 Diabetes Mellitus, Type 2 mangiferin 19.4411315760 9881663
MESH:D003924 Diabetes Mellitus, Type 2 rosiglitazone 19.4412642470
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 19.4417107852
MESH:D003928 Diabetic Nephropathies Curcumin 19.0018204486
MESH:D003928 Diabetic Nephropathies mangiferin 19.0019960420 19706694
MESH:D003928 Diabetic Nephropathies Plant Extracts 19.0019706694
MESH:D003928 Diabetic Nephropathies Tamoxifen 19.0019279558
MESH:D003929 Diabetic Neuropathies Progesterone 4.1317187935
MESH:D003967 Diarrhea Dexamethasone 3.367237001
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 10.7411287661 14550746 16177239 17562736 17906064 10663392 15968718 19370779 11739529 19164858 16081117 16393943 18071297 11529661 19739265 12392966 19085960 12594235 11743745 2444490 18713872 19923254 16109766 12540782 19416960 12153990 16781746 16485898 11461765 19420014 14725611 16227642 10915739 12958197 12705907 17522070 11834606 15619225 11421492 10774834 14986274
MESH:D056486 Drug-Induced Liver Injury Acetylcysteine 10.7411287661
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 10.7419107877
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 10.7420420201
MESH:D056486 Drug-Induced Liver Injury Thioacetamide 10.7412963478
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 3.7219426721
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.4911462148
MESH:D004381 Duodenal Ulcer Curcumin 3.7017351913
MESH:C538011 Eales disease Vitamin E 4.339068938
MESH:D004476 Ectodermal Dysplasia Ethylnitrosourea 5.6118357618
MESH:D004485 Eczema Dexamethasone 4.1112438553
MESH:D004487 Edema Dexamethasone 18.2119703484
MESH:D004487 Edema pirinixic acid 18.2112083418
MESH:D004487 Edema Plant Extracts 18.2112787963
MESH:D004487 Edema rosiglitazone 18.2112083418
MESH:D004487 Edema Tetrachlorodibenzodioxin 18.2112711302 11000095
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 10.6915322242 18230668 16714409
MESH:D004489 Edema, Cardiac Tretinoin 10.6918230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 13.3012538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Progesterone 13.3017692515
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 13.3019031437
MESH:D016889 Endometrial Neoplasms Tamoxifen 6.6317893378 19155303 20544844 16202921
MESH:D016889 Endometrial Neoplasms Tretinoin 6.6316569247
MESH:D004715 Endometriosis Progesterone 7.8716134523
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 7.879294722 10568697
MESH:D004719 Endomyocardial Fibrosis Plant Extracts 5.3115268973
MESH:D004827 Epilepsy Plant Extracts 3.5419700373 19439326
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 4.7416302075
MESH:D004938 Esophageal Neoplasms Paclitaxel 2.8016481741
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 7.9311564622
MESH:D005124 Eye Abnormalities Tretinoin 7.9316938888 9664655
MESH:D005218 Fat Necrosis Thioacetamide 5.3516456712
MESH:D005234 Fatty Liver Curcumin 43.4219297423
MESH:D005234 Fatty Liver Cyclosporine 43.4219224547
MESH:D005234 Fatty Liver Diethylnitrosamine 43.4221071580 20387270
MESH:D005234 Fatty Liver Ethinyl Estradiol 43.4215345470
MESH:D005234 Fatty Liver mangiferin 43.4215975614
MESH:D005234 Fatty Liver pirinixic acid 43.4219236843 20131406
MESH:D005234 Fatty Liver Plant Extracts 43.4215975614
MESH:D005234 Fatty Liver rosiglitazone 43.4219196556
MESH:D005234 Fatty Liver Tamoxifen 43.4219224547 14986274
MESH:D052776 Female Urogenital Diseases Tamoxifen 3.0116709447
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.1011858732
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 4.1614745880
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 3.8119069698
MESH:D005355 Fibrosis Curcumin 23.9318705752
MESH:D005355 Fibrosis Cyclosporine 23.9312168785 12639820
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 23.9320067830
MESH:D005355 Fibrosis Tretinoin 23.9317994277
MESH:D005355 Fibrosis Trinitrobenzenesulfonic Acid 23.9317994277
MESH:D005756 Gastritis Acetaminophen 3.3016983495
MESH:D005770 Gastrointestinal Neoplasms Curcumin 4.3318462866
MESH:D030342 Genetic Diseases, Inborn vinclozolin 4.5716973722
MESH:D005832 Genital Diseases, Male vinclozolin 4.9316417039
MESH:D005833 Genital Neoplasms, Female sodium arsenite 4.3116452187
MESH:D005885 Gingival Hyperplasia Cyclosporine 3.858708960
MESH:D005909 Glioblastoma Curcumin 10.6317596214
MESH:D005909 Glioblastoma Ethylnitrosourea 10.6316436596
MESH:D005909 Glioblastoma Tretinoin 10.6317312396
MESH:D005910 Glioma Ethylnitrosourea 3.3416651633 16357521 18412241
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.2210696789
MESH:D006258 Head and Neck Neoplasms Curcumin 7.0618829502 18462866
MESH:D006258 Head and Neck Neoplasms Tretinoin 7.0616096774
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 4.7816084493
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 9.9810048152 11294989
MESH:D006330 Heart Defects, Congenital Tretinoin 9.989664655 14991402
MESH:D006330 Heart Defects, Congenital Vitamin E 9.9816080930
MESH:D006331 Heart Diseases mangiferin 4.1312093613
MESH:D006333 Heart Failure pirinixic acid 6.4820558911
MESH:D006333 Heart Failure Plant Extracts 6.4818097624
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.0515720958
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.0111000095
MESH:D006501 Hepatic Encephalopathy Thioacetamide 4.2415929193 18665440 17276928
MESH:D006505 Hepatitis Thioacetamide 3.8716456712
MESH:D006529 Hepatomegaly pirinixic acid 7.0719176532 16221962 19772884 18467677
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 7.0712621046 15340226 16120746
MESH:D015417 Hereditary Sensory and Motor Neuropathy Curcumin 4.6817701891
MESH:D006548 Hernia, Diaphragmatic Dexamethasone 5.527520565
MESH:D006548 Hernia, Diaphragmatic Vitamin E 5.5216863852 16490937
MESH:D006561 Herpes Simplex mangiferin 9.2010715843
MESH:D006561 Herpes Simplex Plant Extracts 9.2010715843
MESH:D015658 HIV Infections beta Carotene 6.5816960176
MESH:D015658 HIV Infections Plant Extracts 6.5812878215
MESH:D006689 Hodgkin Disease sodium arsenite 2.8512676792
MESH:D019584 Hot Flashes Plant Extracts 9.1716566672 14716179 17454163
MESH:D019584 Hot Flashes Vitamin E 9.1714716179
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.6718606429 8697196 16959395 15340226 16354765
MESH:D006930 Hyperalgesia Acetaminophen 11.4316870215
MESH:D006930 Hyperalgesia rosiglitazone 11.4312083418
MESH:D006930 Hyperalgesia Tretinoin 11.4316870215
MESH:D006937 Hypercholesterolemia Curcumin 3.7318704882
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 4.2116778211
MESH:D006943 Hyperglycemia pirinixic acid 2.8720558911
MESH:D020138 Hyperhomocysteinemia Plant Extracts 4.1616484555
MESH:D006946 Hyperinsulinism mangiferin 4.699881663 11315760
MESH:D006949 Hyperlipidemias mangiferin 8.7915975614
MESH:D006949 Hyperlipidemias Plant Extracts 8.7915268973 15975614
MESH:D006967 Hypersensitivity mangiferin 4.3816536907
MESH:D006973 Hypertension Cyclosporine 7.7210903974
MESH:D006973 Hypertension Dexamethasone 7.7217042910
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 7.7218850075 18670907
MESH:D007021 Hypospadias Ethinyl Estradiol 3.4516945680 16569931
MESH:D007077 Ileal Diseases 1-Methyl-3-isobutylxanthine 5.0718306037
MESH:D007154 Immune System Diseases mangiferin 5.4816076520
MESH:D020244 Infarction, Middle Cerebral Artery Progesterone 4.0415869954
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.1212013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 9.7817937319
MESH:D007248 Infertility, Male sodium arsenite 9.7815346721 12646999
MESH:D007248 Infertility, Male vinclozolin 9.7816467254
MESH:D007249 Inflammation Curcumin 29.3216956363 18403477 17151092
MESH:D007249 Inflammation Dexamethasone 29.3211099482 8960868
MESH:D007249 Inflammation Diethylnitrosamine 29.3218785209
MESH:D007249 Inflammation mangiferin 29.3215222974
MESH:D007249 Inflammation Plant Extracts 29.3216366677 19332304 15997105 12787963
MESH:D007249 Inflammation Progesterone 29.3215869954
MESH:D007249 Inflammation rosiglitazone 29.3212083418
MESH:D007249 Inflammation Tamoxifen 29.3219457130
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 29.3212200463 12878042
MESH:D015212 Inflammatory Bowel Diseases Curcumin 6.1718596194 18200517
MESH:D015212 Inflammatory Bowel Diseases Trinitrobenzenesulfonic Acid 6.1718200517
MESH:D007251 Influenza, Human Vitamin E 3.8416624496
MESH:D007333 Insulin Resistance mangiferin 11.1711315760
MESH:D007333 Insulin Resistance pirinixic acid 11.1716306350
MESH:D007333 Insulin Resistance rosiglitazone 11.1716306350
MESH:D007410 Intestinal Diseases Tretinoin 8.7917994277
MESH:D007410 Intestinal Diseases Trinitrobenzenesulfonic Acid 8.7917994277
MESH:D007414 Intestinal Neoplasms Curcumin 9.0610783313
MESH:D007414 Intestinal Neoplasms Plant Extracts 9.0612351151 12584176 12628509
MESH:D007511 Ischemia mangiferin 4.9116806951
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 8.8416580747
MESH:D007569 Jaw Abnormalities Tretinoin 8.8415992940 17551590
MESH:D007579 Jejunal Diseases 1-Methyl-3-isobutylxanthine 5.0718306037
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.0715604871
MESH:D007674 Kidney Diseases Acetaminophen 16.7812587719 15629191
MESH:D007674 Kidney Diseases Cyclosporine 16.788314463 10903974 18776723
MESH:D007674 Kidney Diseases mangiferin 16.7812093613
MESH:D007674 Kidney Diseases sodium arsenite 16.7820008137
MESH:D007674 Kidney Diseases Vitamin E 16.7812488133
MESH:D007680 Kidney Neoplasms Cyclosporine 10.7912371664
MESH:D007680 Kidney Neoplasms Ethylnitrosourea 10.7917379185
MESH:D007680 Kidney Neoplasms Tamoxifen 10.7918625569
MESH:D007859 Learning Disorders mangiferin 4.6019182383
MESH:D007889 Leiomyoma Curcumin 4.2318555241
MESH:D007938 Leukemia Curcumin 5.8618462866
MESH:D007938 Leukemia Tretinoin 5.8617143497
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell Curcumin 3.8816106398
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive mangiferin 4.3415498116
MESH:D007951 Leukemia, Myeloid Tretinoin 3.3716482212 19285840 16932348
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 2.0116294345 17596541 19850784
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 2.9117649720 16140955 17107899 17712046 19642359 9834237 17294898 16766008 19035177 12679006 16935935 17368321 17301526 17506722 19075265 15748426 16891316 17217047 17339181 19225113 16823087 16331271 17361223 16788101 19029980
MESH:D015458 Leukemia, T-Cell Curcumin 4.4116106398
MESH:D007984 Leydig Cell Tumor vinclozolin 4.3616417039
MESH:D017880 Limb Deformities, Congenital Tretinoin 3.059224671
MESH:D008064 Lipidoses Tamoxifen 2.8917567588 15342952
MESH:D008080 Liposarcoma Paclitaxel 4.4817353645
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 6.2618522880 19638242 20032147 18665156 18407596
MESH:D008103 Liver Cirrhosis Plant Extracts 6.2617157831
MESH:D008106 Liver Cirrhosis, Experimental Curcumin 19.6618705752 18006644 17355460
MESH:D008106 Liver Cirrhosis, Experimental Dexamethasone 19.6616718785
MESH:D008106 Liver Cirrhosis, Experimental epigallocatechin gallate 19.6617481882
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 19.6615474484
MESH:D008106 Liver Cirrhosis, Experimental Plant Extracts 19.6615479170
MESH:D008106 Liver Cirrhosis, Experimental rosiglitazone 19.6617347453 15980055
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 19.6618564211
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 19.6612878042
MESH:D008106 Liver Cirrhosis, Experimental Thioacetamide 19.6617355460 16126171 16343077 17050028 15095483 18395095 15288472 17127702 18032466 11682029 15078482 18263696 17292413 15288473 11172339 18606216 15316131 12085344 18031379 15075984 17629604 12891558 18380797 11481614 15474484 15716488 18295389 10677585 14739098 15362042 15465738 12557150 15334695 15158331 16489207 16248980 18458672 18416461 12679928 12175628 16511523 12531686 16097051 18615449 16098781
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 19.6618397230 16248980
MESH:D008106 Liver Cirrhosis, Experimental Vitamin E 19.6616169303
MESH:D008107 Liver Diseases Acetaminophen 11.4112969438 16611625 19784758 11587558 19460945 19014921 12587719 16610002
MESH:D008107 Liver Diseases Curcumin 11.4116956363
MESH:D008107 Liver Diseases Diethylnitrosamine 11.4117034775
MESH:D008107 Liver Diseases Plant Extracts 11.4117034775
MESH:D008107 Liver Diseases Thioacetamide 11.4116337175 18374380 15158337
MESH:D017114 Liver Failure, Acute Acetaminophen 8.5816871587 17185352
MESH:D017114 Liver Failure, Acute Thioacetamide 8.5812479984 15633222 17276928 15313186
MESH:D008113 Liver Neoplasms beta-Naphthoflavone 23.3421295105 19389873
MESH:D008113 Liver Neoplasms Clofibric Acid 23.3417602206
MESH:D008113 Liver Neoplasms Diethylnitrosamine 23.3418648771 18978307 20101389 19256749 19426721 19090486 19254457 21047994 15175105 21071580 18644402 20492335 19812893 9163691 19690152 20434301 19294768 2422723 18754104 19996281 18977376 20501860 20137499 2862719 12771043 20405173 19499222 19850985 12112319 19642983 19638242 15885732 16942905 19551842 20452335 21167192 19073162 19255062 19427195 20118626 21278145 19833225 20583210 10737359
MESH:D008113 Liver Neoplasms pirinixic acid 23.3420007298 16377806 15890375
MESH:D008113 Liver Neoplasms Plant Extracts 23.3419168119
MESH:D008113 Liver Neoplasms sodium arsenite 23.3415276417 16712894
MESH:D008113 Liver Neoplasms Tamoxifen 23.3416684651
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 23.3416984957
MESH:D008114 Liver Neoplasms, Experimental beta Carotene 12.2817113696
MESH:D008114 Liver Neoplasms, Experimental beta-Naphthoflavone 12.2818164116
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 12.2819519916 18544905 19004024 18079962 17174075 18775883 21159647 18164116 17942915 18253720 18093689 19126423 17854601 19009564 16267830 19539802 9362446 3124819 18282651 16842330 2563599 18308698
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 12.2812151625
MESH:D008171 Lung Diseases Acetylcysteine 11.0212815614
MESH:D008171 Lung Diseases sodium arsenite 11.0219095001
MESH:D008171 Lung Diseases Vitamin E 11.0216863852
MESH:D008175 Lung Neoplasms Acetaldehyde 21.9417372256
MESH:D008175 Lung Neoplasms beta Carotene 21.9416401635
MESH:D008175 Lung Neoplasms Curcumin 21.9419359593 18462866 16243823
MESH:D008175 Lung Neoplasms Dexamethasone 21.9415824018 11195469
MESH:D008175 Lung Neoplasms Diethylnitrosamine 21.9421163286 20512841 6695378 20970405
MESH:D008175 Lung Neoplasms Ethylnitrosourea 21.9416019985 16271038 6695378 17703301
MESH:D008175 Lung Neoplasms mangiferin 21.9418520028 18569708 18816296
MESH:D008175 Lung Neoplasms Plant Extracts 21.9420869020
MESH:D008175 Lung Neoplasms sodium arsenite 21.9417077188 16712894 17306315 15276417 19931552
MESH:D008175 Lung Neoplasms Tamoxifen 21.9418625569
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 21.9419555203 11884234
MESH:D008175 Lung Neoplasms Vitamin E 21.9411062179
MESH:D008223 Lymphoma Curcumin 7.0918462866
MESH:D008223 Lymphoma Ethylnitrosourea 7.0915790496
MESH:D008228 Lymphoma, Non-Hodgkin Paclitaxel 3.7914749477
MESH:D016399 Lymphoma, T-Cell Curcumin 10.5416173963
MESH:D016399 Lymphoma, T-Cell Ethylnitrosourea 10.5415375218
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 3.3919428831
MESH:D008325 Mammary Neoplasms, Experimental Ethylnitrosourea 12.3918041768 10767621 10838139
MESH:D008325 Mammary Neoplasms, Experimental Progesterone 12.3917203775 11408345
MESH:D008325 Mammary Neoplasms, Experimental rosiglitazone 12.3916827153
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 12.3911731420 19196722 14580682 16827153 19196723
MESH:D020149 Manganese Poisoning Tamoxifen 4.1719453300
MESH:D008527 Medulloblastoma Tretinoin 2.6317453147
MESH:D008545 Melanoma Curcumin 11.5318462866 17885582
MESH:D008545 Melanoma epigallocatechin gallate 11.5317992120 11746506
MESH:D008545 Melanoma Paclitaxel 11.5316342250 12025231 12040289
MESH:D008545 Melanoma sodium arsenite 11.5316487513 19082730
MESH:D008545 Melanoma Tamoxifen 11.5319393235 12393984
MESH:D008545 Melanoma Tretinoin 11.5316752155
MESH:D018328 Melanoma, Amelanotic Tamoxifen 3.8115990972
MESH:D008546 Melanoma, Experimental Acetaminophen 3.2119513568
MESH:D008569 Memory Disorders Curcumin 8.8717263510
MESH:D008569 Memory Disorders mangiferin 8.8719182383
MESH:D008579 Meningioma Ethylnitrosourea 5.6117943659
MESH:D008591 Meningomyelocele Tretinoin 4.0616940565
MESH:D024821 Metabolic Syndrome X rosiglitazone 4.0817261469
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.4116801185
MESH:D009101 Multiple Myeloma Curcumin 10.7719372569
MESH:D009101 Multiple Myeloma Dexamethasone 10.7715744524 16118317 15867202
MESH:D009101 Multiple Myeloma Paclitaxel 10.7714749477
MESH:D009134 Muscular Atrophy, Spinal Curcumin 11.4117962980
MESH:D009134 Muscular Atrophy, Spinal epigallocatechin gallate 11.4117962980
MESH:D009135 Muscular Diseases pirinixic acid 3.1516239165
MESH:D009190 Myelodysplastic Syndromes Dexamethasone 6.829809623
MESH:D009190 Myelodysplastic Syndromes Tretinoin 6.8217596541
MESH:D009203 Myocardial Infarction mangiferin 5.5117052832 16584858 19172585 16697266 16538859
MESH:D009203 Myocardial Infarction pirinixic acid 5.5119151258
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 2.7312213967
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 2.6716411023
MESH:D009361 Neoplasm Invasiveness Curcumin 4.0218495463
MESH:D009362 Neoplasm Metastasis Acetylcysteine 12.3714720322
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 12.373581430 9029167
MESH:D009362 Neoplasm Metastasis Paclitaxel 12.3715867366
MESH:D009362 Neoplasm Metastasis Tamoxifen 12.3719393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.3919410462
MESH:D009369 Neoplasms beta Carotene 10.3617051425
MESH:D009369 Neoplasms pirinixic acid 10.3617405874
MESH:D009369 Neoplasms sodium arsenite 10.3611559025
MESH:D009369 Neoplasms Tretinoin 10.3616594593 16946489
MESH:D009374 Neoplasms, Experimental Ethylnitrosourea 8.1816707424
MESH:D009374 Neoplasms, Experimental sodium arsenite 8.1820056578
MESH:D009376 Neoplasms, Hormone-Dependent Curcumin 9.5912497104
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 9.5919200415 19196722 19189210
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.0717954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 2.9818481113 19348381
MESH:D009410 Nerve Degeneration mangiferin 4.3317433543
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 8.3514600291
MESH:D009421 Nervous System Malformations Tretinoin 8.359125849
MESH:D009423 Nervous System Neoplasms Curcumin 5.2618462866
MESH:D009436 Neural Tube Defects Acetylcysteine 10.8819446573
MESH:D009436 Neural Tube Defects sodium arsenite 10.8812854658
MESH:D009436 Neural Tube Defects Tretinoin 10.889142499
MESH:D009442 Neurilemmoma Ethylnitrosourea 5.0516651423 17160924 16003739
MESH:D019954 Neurobehavioral Manifestations Plant Extracts 4.8217168769
MESH:D019636 Neurodegenerative Diseases Acetaminophen 7.1918514411
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 7.1920387270
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 4.7420387270
MESH:D009765 Obesity Curcumin 6.9519297423
MESH:D009765 Obesity pirinixic acid 6.9520558911
MESH:D009765 Obesity Plant Extracts 6.9520132043 19056576
MESH:D009837 Oligodendroglioma Ethylnitrosourea 5.6117160924
MESH:D010014 Osteolysis Paclitaxel 4.6115867366
MESH:D010024 Osteoporosis Curcumin 3.2418719352
MESH:D010051 Ovarian Neoplasms Curcumin 13.6518462866 19020741
MESH:D010051 Ovarian Neoplasms Paclitaxel 13.6511161223
MESH:D010051 Ovarian Neoplasms Progesterone 13.6517393432 16525653
MESH:D010051 Ovarian Neoplasms sodium arsenite 13.6517306315 15276417
MESH:D010051 Ovarian Neoplasms Tretinoin 13.6516936753
MESH:D010146 Pain Acetaminophen 5.6216870215
MESH:D010146 Pain Tretinoin 5.6216870215
MESH:D010190 Pancreatic Neoplasms Curcumin 7.8419401701 17440100 19196508
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 7.8416540662
MESH:D010190 Pancreatic Neoplasms Tretinoin 7.8415976015
MESH:D010195 Pancreatitis Trinitrobenzenesulfonic Acid 3.8717698068
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.3511578682
MESH:D010212 Papilloma Plant Extracts 4.1415173996 16517061
MESH:D010300 Parkinson Disease mangiferin 3.5717433543
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 3.8712520081
MESH:D010518 Periodontitis mangiferin 5.2319026997
OMIM:175780 PORENCEPHALY, FAMILIAL marker/mechanism
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.2118163543
MESH:D011230 Precancerous Conditions Cyclosporine 7.9212371664
MESH:D011230 Precancerous Conditions Diethylnitrosamine 7.922563599
MESH:D054198 Precursor Cell Lymphoblastic Leukemia-Lymphoma Dexamethasone 3.3421297632
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 8.2711399792 11118676 11896295 11222880
MESH:D011297 Prenatal Exposure Delayed Effects vinclozolin 8.2718042343 19015723 18220299
MESH:D011469 Prostatic Diseases vinclozolin 4.5718220299
MESH:D011471 Prostatic Neoplasms Cholecalciferol 2.0417024972
MESH:D011471 Prostatic Neoplasms Curcumin 2.0411398177 10851300 12497104 15129424 18156803 18226269 18769126
MESH:D011471 Prostatic Neoplasms Paclitaxel 2.0417172428 16729912 17136230 16356831
MESH:D011471 Prostatic Neoplasms Plant Extracts 2.0417804756 14666653
MESH:D011471 Prostatic Neoplasms sodium arsenite 2.0416039940
MESH:D011471 Prostatic Neoplasms Tamoxifen 2.0415067354
MESH:D011471 Prostatic Neoplasms Vitamin E 2.0415084515
MESH:D011472 Prostatitis vinclozolin 4.5718629315
MESH:D011507 Proteinuria Tretinoin 3.2716636307
MESH:D011537 Pruritus Ethinyl Estradiol 2.9515861022 16919318
MESH:D011565 Psoriasis Cyclosporine 2.1016882103
MESH:D011625 Pterygium Tretinoin 4.4216723453
MESH:D011656 Pulmonary Emphysema Curcumin 4.2119168576
MESH:D011833 Radiation Injuries, Experimental mangiferin 6.0315830843
MESH:D015427 Reperfusion Injury pirinixic acid 2.2019058328
MESH:D012128 Respiratory Distress Syndrome, Adult Acetylcysteine 13.3812210543
MESH:D012128 Respiratory Distress Syndrome, Adult Curcumin 13.3810666014 18379247
MESH:D012128 Respiratory Distress Syndrome, Adult Dexamethasone 13.3811700416 18379247
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.4918990726
MESH:D012208 Rhabdomyosarcoma Tretinoin 3.7616116481 16283617
MESH:D012220 Rhinitis Acetaldehyde 4.4317050345
MESH:D012468 Salivary Gland Neoplasms Progesterone 2.7218045962
MESH:D012509 Sarcoma Curcumin 3.8018462866
MESH:D018805 Sepsis Curcumin 3.7818389075
MESH:D012772 Shock, Septic mangiferin 4.8715177305
MESH:D012871 Skin Diseases Vitamin E 2.3418709164
MESH:D012878 Skin Neoplasms Plant Extracts 16.0216517061 15173996
MESH:D012878 Skin Neoplasms sodium arsenite 16.0218572023 19524636
MESH:D012878 Skin Neoplasms tert-Butylhydroperoxide 16.028532709
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 16.0216192470
MESH:D012878 Skin Neoplasms Tretinoin 16.0216467112
MESH:D013088 Spermatocele Ethinyl Estradiol 10.3116709447
MESH:D013088 Spermatocele Tamoxifen 10.3116709447
MESH:D013119 Spinal Cord Injuries Progesterone 9.6516503802 15862959
MESH:D013119 Spinal Cord Injuries Tamoxifen 9.6519457130
MESH:D016135 Spinal Dysraphism sodium arsenite 3.5112854658
MESH:D013272 Stomach Diseases beta Carotene 9.3917638125
MESH:D013272 Stomach Diseases Dexamethasone 9.3915472012
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 3.2218456281
MESH:D013274 Stomach Neoplasms Paclitaxel 3.2218506536 18396642
MESH:D013274 Stomach Neoplasms Tretinoin 3.2217261132
MESH:D013276 Stomach Ulcer Acetylcysteine 23.9017918041
MESH:D013276 Stomach Ulcer beta Carotene 23.9012500499
MESH:D013276 Stomach Ulcer Curcumin 23.9016631530 19188055
MESH:D013276 Stomach Ulcer Dexamethasone 23.9015138204
MESH:D013276 Stomach Ulcer mangiferin 23.9017918041
MESH:D013276 Stomach Ulcer Plant Extracts 23.9018193104 15255614 12787963 18237397 17135157
MESH:D020521 Stroke Vitamin E 3.2316517955
MESH:D024801 Tauopathies Paclitaxel 4.4416930453
MESH:D013705 Temporomandibular Joint Disorders Plant Extracts 5.1017997062
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.2811994571
MESH:D013927 Thrombosis Ethinyl Estradiol 2.8515669648
MESH:D013953 Thymus Neoplasms Ethylnitrosourea 4.7915790496
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.5312697716
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 6.257505956
MESH:D013964 Thyroid Neoplasms Tretinoin 6.2517045167 16026305
MESH:D014062 Tongue Neoplasms Tretinoin 3.4716051514
MESH:D014235 Trichinellosis mangiferin 5.6914669257
MESH:D014376 Tuberculosis Tretinoin 3.0016040207
MESH:D001749 Urinary Bladder Neoplasms Curcumin 7.5118593936
MESH:D001749 Urinary Bladder Neoplasms sodium arsenite 7.5116712894 11723127 17306315 16452187
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 7.5116712894 8653321 17572228
MESH:D014565 Urogenital Neoplasms Curcumin 4.9018462866
MESH:D014581 Urticaria Acetaminophen 2.6410982225
MESH:D002583 Uterine Cervical Neoplasms sodium arsenite 8.3511813266
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 8.3516129372
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 2.9514692618
MESH:D014604 Uveal Neoplasms Tretinoin 4.2416752155
MESH:D014605 Uveitis Cyclosporine 10.521336536
MESH:D014605 Uveitis Dexamethasone 10.521336536
MESH:D014652 Vascular Diseases sodium arsenite 4.0617056641
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.2212125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.2115869587 14671159
MESH:D018487 Ventricular Dysfunction, Left Plant Extracts 4.3918097624
MESH:D020257 Ventricular Remodeling Plant Extracts 4.9518097624
MESH:D014820 Vitiligo Tretinoin 3.7116761959
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 3.8715886252
MESH:D009396 Wilms Tumor Tretinoin 3.6616287080
MESH:D014947 Wounds and Injuries Plant Extracts 3.9619894650 20213670
MESH:D014985 Xerophthalmia Cyclosporine 4.0717120751
Pathway ID Pathway Name
KEGG:05146 Amoebiasis
REACT:18266 Axon guidance
KEGG:04512 ECM-receptor interaction
KEGG:04510 Focal adhesion
REACT:13552 Integrin cell surface interactions
KEGG:05200 Pathways in cancer
KEGG:04974 Protein digestion and absorption
REACT:16888 Signaling by PDGF
KEGG:05222 Small cell lung cancer
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA26717
    • No data
    Releated disease ID Related disease Name
    PA443635Cardiovascular Diseases
    PA445019Myocardial Infarction
    Releated drug ID Related drug Name
    PA164744376adenosine monophosphate
    PA164743471adenosine triphosphate
    PA449470epinephrine
    Drug Bank Top

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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