AutismKB 2.0

Annotation Detail for COL5A1


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Basic Information Top
Gene Symbol:COL5A1 ( - )
Gene Full Name: collagen, type V, alpha 1
Band: 9q34.3
Quick LinksEntrez ID:1289; OMIM: 120215; Uniprot ID:CO5A1_HUMAN; ENSEMBL ID: ENSG00000130635; HGNC ID: 2209
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa05146Amoebiasis
hsa04974Protein digestion and absorption
hsa04512ECM-receptor interaction
hsa04510Focal adhesion
Pathway IDPathway Name
Axon guidance
Signaling by PDGF
No data
Pathway IDPathway Name
P00034Integrin signalling pathway
No data
Related Diseases/Disorders Top
No data
No data
Desease Name
Rupture
Achilles tendinopathy
Achilles tendon pathology
Knee Injuries
range of motion measurements
Desease Name
Central corneal thickness
Desease Name
Ehlers-Danlos syndrome, type II
Ehlers-Danlos syndrome, type I
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C075773 4-phenylbutyric acid 4-phenylbutyric acid results in increased expression of COL5A1 mRNAincreases expression 14583596
C000188 alachlor alachlor results in increased expression of COL5A1 mRNAincreases expression 12419858
D019386 Alendronate Alendronate affects the expression of COL5A1 mRNAaffects expression 16079270
D017638 Asbestos, Crocidolite Asbestos, Crocidolite results in decreased expression of COL5A1 mRNAdecreases expression 18687144
C006780 bisphenol A bisphenol A results in increased expression of COL5A1 mRNAincreases expression 12075121
D020122 tert-Butylhydroperoxide tert-Butylhydroperoxide results in decreased expression of COL5A1 mRNAdecreases expression 15336504
D002251 Carbon Tetrachloride Carbon Tetrachloride results in increased expression of COL5A1 mRNAincreases expression 17484886
D002251 Carbon Tetrachloride Carbon Tetrachloride results in increased expression of COL5A1 mRNAincreases expression 17056239
D003474 Curcumin Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of COL5A1 mRNA]decreases reaction|increases expression 18200517
D016572 Cyclosporine Cyclosporine results in increased expression of COL5A1 mRNAincreases expression 20106945
D004041 Dietary Fats Dietary Fats results in increased expression of COL5A1 mRNAincreases expression 18042831
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of COL5A1 mRNAaffects expression 17555576
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of COL5A1 mRNAincreases expression 17942748
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of COL5A1 mRNAaffects cotreatment|increases expression 17942748
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of COL5A1 mRNAaffects expression 16079270
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of COL5A1 mRNAincreases expression 12075121
12655037
D019833 Genistein Genistein results in increased expression of COL5A1 mRNAincreases expression 12075121
D008748 Methylcholanthrene Methylcholanthrene results in decreased expression of COL5A1 mRNAdecreases expression 20713471
D010126 Ozone Ozone affects the expression of COL5A1 mRNAaffects expression 16716893
C041786 palm oil palm oil results in increased expression of COL5A1 mRNAincreases expression 18042831
C006253 pirinixic acid [pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of COL5A1 mRNAaffects binding|increases activity|increases expression 19710929
C006253 pirinixic acid pirinixic acid results in decreased expression of COL5A1 mRNAdecreases expression 17426115
D020849 Raloxifene Raloxifene affects the expression of COL5A1 mRNAaffects expression 16079270
D013629 Tamoxifen Tamoxifen affects the expression of COL5A1 mRNAaffects expression 17555576
C004648 testosterone enanthate testosterone enanthate affects the expression of COL5A1 mRNAaffects expression 17440010
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin affects the expression of COL5A1 mRNAaffects expression 16962184
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of COL5A1 mRNAaffects cotreatment|increases expression 17942748
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of COL5A1 mRNAincreases expression 17942748
D014212 Tretinoin Tretinoin results in increased expression of COL5A1 mRNAincreases expression 16604517
D014302 Trinitrobenzenesulfonic Acid Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of COL5A1 mRNA]decreases reaction|increases expression 18200517
D014302 Trinitrobenzenesulfonic Acid Trinitrobenzenesulfonic Acid results in increased expression of COL5A1 mRNAincreases expression 18200517
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 4.4214745880
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 2.7215322242 11752688 14514962
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.8117505938
MESH:D055371 Acute Lung Injury pirinixic acid 2.9918653653
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 4.2514692618
MESH:D000230 Adenocarcinoma Genistein 4.2511473722
MESH:D000236 Adenoma Methylcholanthrene 3.4210545420 6695378
MESH:D018248 Adenoma, Liver Cell pirinixic acid 9.4616434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 9.4616835633
MESH:D000382 Agricultural Workers' Diseases alachlor 4.5314769641 11874814
MESH:D000419 Albuminuria Raloxifene 4.4717451421 17308373
MESH:D019973 Alcohol-Related Disorders Curcumin 4.9517887948
MESH:D000505 Alopecia Tretinoin 3.5115955085
MESH:D000544 Alzheimer Disease Curcumin 6.5515590663
MESH:D000544 Alzheimer Disease Ozone 6.5515513908
MESH:D000544 Alzheimer Disease Raloxifene 6.5515800139
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.8311748828
MESH:D001161 Arteriosclerosis Dietary Fats 9.4715238619
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 9.4711256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 6.9415885639
MESH:D001169 Arthritis, Experimental Tretinoin 6.9416412693
MESH:D001172 Arthritis, Rheumatoid Curcumin 7.2816807698
MESH:D001172 Arthritis, Rheumatoid Ozone 7.2815570426
MESH:D001172 Arthritis, Rheumatoid Tretinoin 7.2816292516
MESH:D001249 Asthma Ozone 4.8216373670 17854713
MESH:D001249 Asthma Tretinoin 4.8216456186
MESH:D050197 Atherosclerosis Curcumin 6.7318704882
MESH:D050197 Atherosclerosis Methylcholanthrene 6.7311922910
MESH:D001327 Autoimmune Diseases Curcumin 4.3619761891
MESH:D001471 Barrett Esophagus Tretinoin 4.2716935849
MESH:D001778 Blood Coagulation Disorders pirinixic acid 14.5719483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 14.5712125929
MESH:D001778 Blood Coagulation Disorders Tretinoin 14.5716206674 16197459
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.6615340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.6815746008
MESH:D001862 Bone Resorption bisphenol A 3.7411985600
MESH:D001930 Brain Injuries Raloxifene 4.3416580743
MESH:D002545 Brain Ischemia Curcumin 4.2016770732
MESH:D001932 Brain Neoplasms Curcumin 3.8217596214
MESH:D001943 Breast Neoplasms bisphenol A 5.7117123778
MESH:D001943 Breast Neoplasms Curcumin 5.7118593918 16243823 19250217 18462866
MESH:D001943 Breast Neoplasms Dietary Fats 5.7120435547
MESH:D001943 Breast Neoplasms Genistein 5.7116541309 17200150 16873071
MESH:D001943 Breast Neoplasms Methylcholanthrene 5.7117474063
MESH:D001943 Breast Neoplasms Raloxifene 5.7116912660 17049068 15572757 16837676 17952589 17440819 17261762 17242785 15758505 15775269 17893378 17595753
MESH:D001943 Breast Neoplasms Tamoxifen 5.7119221464 15565566 19200415 18629630 18815881 19155303 20859285 15668708 20390343 19142967 17893378 19011961 17261762 20544844 19288272 11161223 21152245 19084267 19189212 20135344 19189210 19410462 19115204 20005174 16273361 18425577 21138602 19487384 19066611 17049068 17440819 16818667 18855134 18351453 19059307 20065188 16873071 19289846 19244106 18997820 18984771 17242785 18821012 16202921 19103187
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 5.7120435547
MESH:D001943 Breast Neoplasms Tretinoin 5.7116873071 16443354 16166294
MESH:D016535 Bronchial Hyperreactivity Ozone 3.5716777450 18315731 17626835 15516495 18417511 14754758 19059883
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 4.4616813970
MESH:D002100 Cachexia Ozone 4.6116183385
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 3.6518705752 3786805 16011737 10355542 16192424 16227642 16097048 15673190 16050911 15700767 16124888 15721981
MESH:D002277 Carcinoma Curcumin 13.4218593918
MESH:D002277 Carcinoma Methylcholanthrene 13.4210545420
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 13.4216835633
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 4.3819066611
MESH:D018236 Carcinoma, Embryonal Tretinoin 5.0316168501
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 6.4218788625
MESH:D006528 Carcinoma, Hepatocellular Genistein 6.4216924424
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 6.4216924424
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 6.421917145
MESH:D002278 Carcinoma in Situ bisphenol A 4.8617123778
MESH:D002289 Carcinoma, Non-Small-Cell Lung Curcumin 2.9318414057
MESH:D002294 Carcinoma, Squamous Cell Curcumin 4.7018462866
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 4.7016096774 16051514
MESH:D002295 Carcinoma, Transitional Cell Raloxifene 9.1117572228
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 9.1117572228
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.3018850075 16120746 18670907
MESH:D002318 Cardiovascular Diseases Genistein 7.2016332659
MESH:D002318 Cardiovascular Diseases Raloxifene 7.2015775269
MESH:D002386 Cataract Tretinoin 3.0217460283
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 6.5412371664
MESH:D002471 Cell Transformation, Neoplastic Methylcholanthrene 6.5416192471
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 4.4616129372
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 3.0516835633
MESH:D002779 Cholestasis Cyclosporine 12.7819486331
MESH:D002779 Cholestasis Ethinyl Estradiol 12.7817110522 16919318 17333356 11677210 15861022 17681005 16105132
MESH:D002779 Cholestasis pirinixic acid 12.7819176532
MESH:D002822 Choriocarcinoma Tretinoin 5.0316461808
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 5.588697196 15668235 16354765 12621046 15340226
MESH:D002972 Cleft Palate Tretinoin 5.589407595
MESH:D003072 Cognition Disorders Raloxifene 4.4915800139
MESH:D003092 Colitis Curcumin 15.4018200517 16804969 16782535
MESH:D003092 Colitis Tretinoin 15.4017035595
MESH:D003092 Colitis Trinitrobenzenesulfonic Acid 15.4018023891 18200517 17936198 16474422 16804969 16782535 16867261 17991707 11698051
MESH:D003093 Colitis, Ulcerative Trinitrobenzenesulfonic Acid 3.4017276891
MESH:D003103 Coloboma Curcumin 4.4318809619
MESH:D003110 Colonic Neoplasms Curcumin 3.8716340194 19359593
MESH:D003110 Colonic Neoplasms Genistein 3.8717182828
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 2.9514669216 17141729
MESH:D016510 Corneal Neovascularization Curcumin 4.7718497527
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 2.4110048152 20055451 15322242
MESH:D019465 Craniofacial Abnormalities Tretinoin 2.419211117 10589399 16925845 17551590 9142499 9125849 9224671 9664655 8800419 14991402
MESH:D003711 Demyelinating Diseases Tamoxifen 4.2319031437
MESH:D003865 Depressive Disorder, Major Raloxifene 4.0517474826
MESH:D017449 Dermatitis, Allergic Contact alachlor 4.068428444
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.3718249437
MESH:D003924 Diabetes Mellitus, Type 2 Curcumin 6.9818403477
MESH:D003924 Diabetes Mellitus, Type 2 Genistein 6.9816647724
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 6.9817107852
MESH:D003928 Diabetic Nephropathies Curcumin 14.4518204486
MESH:D003928 Diabetic Nephropathies Raloxifene 14.4517451421 17308373 15920148
MESH:D003928 Diabetic Nephropathies Tamoxifen 14.4519279558
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 3.6010092053 6623471 7179309 3732212 19336974 15998439 15027814 3786805 6884620 7120509 11566570 16177239 4309450 19085960 7440962 16227642 2869522 10915739 21278145 9327722 15968718 17522070
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 3.6020420201
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.6611462148
MESH:D004381 Duodenal Ulcer Curcumin 3.9217351913
MESH:D050171 Dyslipidemias Dietary Fats 3.3618367378
MESH:D004487 Edema pirinixic acid 10.7312083418
MESH:D004487 Edema Raloxifene 10.7315860553
MESH:D004487 Edema Tetrachlorodibenzodioxin 10.7312711302 11000095
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 11.5118230668 15322242 16714409
MESH:D004489 Edema, Cardiac Tretinoin 11.5118230668
MESH:C536194 Ehlers-Danlos syndrome type 1 marker/mechanism
MESH:C536195 Ehlers-Danlos syndrome type 2 marker/mechanism
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 14.6112538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Raloxifene 14.6115845917
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 14.6119031437
MESH:D004714 Endometrial Hyperplasia Genistein 4.4616402032
MESH:D016889 Endometrial Neoplasms Genistein 11.9811473722
MESH:D016889 Endometrial Neoplasms Tamoxifen 11.9816202921 19155303 20544844 17893378
MESH:D016889 Endometrial Neoplasms Tretinoin 11.9816569247
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 2.9110568697 9294722
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 8.5111564622
MESH:D005124 Eye Abnormalities Tretinoin 8.519664655 16938888
MESH:D005234 Fatty Liver Carbon Tetrachloride 41.3412795759 17595544 15959796 61145 19224547 12631006 16045604 16239168
MESH:D005234 Fatty Liver Curcumin 41.3419297423
MESH:D005234 Fatty Liver Cyclosporine 41.3419224547
MESH:D005234 Fatty Liver Dietary Fats 41.3419551842 19004024 18296743 17967931
MESH:D005234 Fatty Liver Ethinyl Estradiol 41.3415345470
MESH:D005234 Fatty Liver pirinixic acid 41.3420131406 19236843
MESH:D005234 Fatty Liver Raloxifene 41.3417473493
MESH:D005234 Fatty Liver Tamoxifen 41.3419224547 14986274
MESH:D052776 Female Urogenital Diseases Tamoxifen 3.1616709447
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.3311858732
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 4.4014745880
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 4.0519069698
MESH:D005354 Fibrosarcoma Methylcholanthrene 4.8114633661 10962813
MESH:D005355 Fibrosis Carbon Tetrachloride 39.5418705752
MESH:D005355 Fibrosis Curcumin 39.5418705752
MESH:D005355 Fibrosis Cyclosporine 39.5412168785 12639820
MESH:D005355 Fibrosis Dietary Fats 39.5418296743
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 39.5420067830
MESH:D005355 Fibrosis Tretinoin 39.5417994277
MESH:D005355 Fibrosis Trinitrobenzenesulfonic Acid 39.5417994277
MESH:D005770 Gastrointestinal Neoplasms Curcumin 4.5618462866
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.098708960
MESH:D005909 Glioblastoma Curcumin 11.4617596214
MESH:D005909 Glioblastoma Genistein 11.4616598420
MESH:D005909 Glioblastoma Tretinoin 11.4617312396
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.4710696789
MESH:D006258 Head and Neck Neoplasms Curcumin 7.6018829502 18462866
MESH:D006258 Head and Neck Neoplasms Tretinoin 7.6016096774
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 5.0316084493
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 6.3111294989 10048152
MESH:D006330 Heart Defects, Congenital Tretinoin 6.319664655 14991402
MESH:D006331 Heart Diseases Raloxifene 3.4411110106
MESH:D006333 Heart Failure pirinixic acid 2.4620558911
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.2915720958
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.2111000095
MESH:D006505 Hepatitis Carbon Tetrachloride 3.4719900420 19110552
MESH:D006529 Hepatomegaly pirinixic acid 7.8319772884 18467677 16221962 19176532
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 7.8315340226 16120746 12621046
MESH:D015417 Hereditary Sensory and Motor Neuropathy Curcumin 4.9117701891
MESH:D019247 HIV Wasting Syndrome testosterone enanthate 5.6217440010
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.9218606429 16354765 15340226 16959395 8697196
MESH:D006930 Hyperalgesia Alendronate 8.0216769263
MESH:D006930 Hyperalgesia Tretinoin 8.0216870215
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 4.4016899240
MESH:D006937 Hypercholesterolemia Curcumin 8.8318704882
MESH:D006937 Hypercholesterolemia Dietary Fats 8.8321332399
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 4.4416778211
MESH:D006943 Hyperglycemia pirinixic acid 3.0720558911
MESH:D006949 Hyperlipidemias Dietary Fats 3.4921332399
MESH:D006973 Hypertension Cyclosporine 8.2910903974
MESH:D006973 Hypertension Raloxifene 8.2917577099 15787275
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 8.2918670907 18850075
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 3.9615338365
MESH:D007021 Hypospadias Ethinyl Estradiol 3.6816569931 16945680
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.3412013081
MESH:D007248 Infertility, Male alachlor 6.7816466525 12948887 17049205
MESH:D007248 Infertility, Male Ethinyl Estradiol 6.7817937319
MESH:D007249 Inflammation Curcumin 11.4117151092 18403477 16956363
MESH:D007249 Inflammation Dietary Fats 11.4120412841
MESH:D007249 Inflammation Tamoxifen 11.4119457130
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 11.4112878042 12200463
MESH:D015212 Inflammatory Bowel Diseases Curcumin 6.5218200517 18596194
MESH:D015212 Inflammatory Bowel Diseases Trinitrobenzenesulfonic Acid 6.5218200517
MESH:D007333 Insulin Resistance bisphenol A 11.8416393666
MESH:D007333 Insulin Resistance Dietary Fats 11.8411836018 18457598
MESH:D007333 Insulin Resistance pirinixic acid 11.8416306350
MESH:D007410 Intestinal Diseases Tretinoin 9.5517994277
MESH:D007410 Intestinal Diseases Trinitrobenzenesulfonic Acid 9.5517994277
MESH:D007414 Intestinal Neoplasms Curcumin 4.1010783313
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 9.5316580747
MESH:D007569 Jaw Abnormalities Tretinoin 9.5317551590 15992940
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.3115604871
MESH:D007674 Kidney Diseases Cyclosporine 2.278314463 10903974 18776723
MESH:D007680 Kidney Neoplasms Cyclosporine 6.9412371664
MESH:D007680 Kidney Neoplasms Tamoxifen 6.9418625569
MESH:D007889 Leiomyoma Curcumin 10.7418555241
MESH:D007889 Leiomyoma Raloxifene 10.7416973256
MESH:D007938 Leukemia alachlor 14.5114769641
MESH:D007938 Leukemia Curcumin 14.5118462866
MESH:D007938 Leukemia Genistein 14.5118980019 17468513
MESH:D007938 Leukemia Tretinoin 14.5117143497
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell Curcumin 4.0816106398
MESH:D007951 Leukemia, Myeloid Tretinoin 3.5816482212 19285840 16932348
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 2.0619850784 16294345 17596541
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 3.0717712046 17649720 19075265 16788101 17361223 17506722 17107899 15748426 17294898 12679006 16823087 19225113 16891316 17339181 9834237 17368321 16766008 19642359 19029980 19035177 17301526 17217047 16935935 16331271 16140955
MESH:D015458 Leukemia, T-Cell Curcumin 4.6316106398
MESH:D017880 Limb Deformities, Congenital Tretinoin 3.219224671
MESH:D008064 Lipidoses Tamoxifen 3.0615342952 17567588
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 6.3916943688 11903743 11408273 17174718 16239168 21278145 16221502 17334410 17157831
MESH:D008103 Liver Cirrhosis Dietary Fats 6.3918296743
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 10.6815818738 18006644 17721639 12898905 17708605 15650968 12741479 18277467 10355542 12649538 18279442 17698563 18205269 18251166 17714472 18412020 12586293 12389079 15123356 18210741 18339082 18395914 17761835 14512876 15362042 18705752 15996030 12632514 12667390 17557913 18187930 12666154 16011737 17565644 17976157 17481882 12445421 12445418 18166357 17922224 17640975 18376398 15876570 15673190 18395095 15057751 12609069 17944888 18420326 16015684 16027843 20821823 15959796 15370692 14716833 17805973 18263696 16136751 18429990 15925388 18156304 18472332 12958196 14716496 17631135 14724832 13678700 11481614 16192424 16116963 12632512 14748882 15052691 17869086 18481824 18472094 17900296 12546737 18418968 17823541 17766677 15338365 16097048 14620537 17525996 16248980 16033810 16638106 18317297 15730626 15893842 15931870 18054572
MESH:D008106 Liver Cirrhosis, Experimental Curcumin 10.6817355460 18006644 18705752
MESH:D008106 Liver Cirrhosis, Experimental Genistein 10.6817823541
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 10.6815474484
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 10.6818564211
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 10.6812878042
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 10.6816248980 18397230
MESH:D008107 Liver Diseases Carbon Tetrachloride 4.1516246199 17285989 15720792 15830285 16964402
MESH:D008107 Liver Diseases Curcumin 4.1516956363
MESH:D017093 Liver Failure Carbon Tetrachloride 4.0315123358
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 3.5714706259 16899240
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 10.2619294768
MESH:D008113 Liver Neoplasms pirinixic acid 10.2620007298 16377806 15890375
MESH:D008113 Liver Neoplasms Tamoxifen 10.2616684651
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 10.2616984957
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 9.4115583823 12014681
MESH:D008114 Liver Neoplasms, Experimental Methylcholanthrene 9.41598648 1399818
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 9.4112151625
MESH:D008171 Lung Diseases Ozone 3.2919066396 8266340
MESH:D055370 Lung Injury Asbestos, Crocidolite 8.8117365036
MESH:D055370 Lung Injury Ozone 8.8120417186
MESH:D008175 Lung Neoplasms Curcumin 6.4318462866 16243823 19359593
MESH:D008175 Lung Neoplasms Methylcholanthrene 6.437750092 11893704 16337739 20512841 21163286 20970405 9230183 10545420 15390079 6695378 1399818 17909032 16271038
MESH:D008175 Lung Neoplasms Ozone 6.437614698 8597069
MESH:D008175 Lung Neoplasms Tamoxifen 6.4318625569
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 6.4319555203 11884234
MESH:D008223 Lymphoma Curcumin 3.4918462866
MESH:D016399 Lymphoma, T-Cell Curcumin 4.5616173963
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 3.6319428831
MESH:D008325 Mammary Neoplasms, Experimental Genistein 5.8314578162 12929590
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 5.8311731420 19196723 14580682 19196722 16827153
MESH:D020149 Manganese Poisoning Tamoxifen 4.4219453300
MESH:D008527 Medulloblastoma Tretinoin 2.7317453147
MESH:D008545 Melanoma Curcumin 5.0118462866 17885582
MESH:D008545 Melanoma Tamoxifen 5.0112393984 19393235
MESH:D008545 Melanoma Tretinoin 5.0116752155
MESH:D018328 Melanoma, Amelanotic Tamoxifen 4.0515990972
MESH:D008569 Memory Disorders Curcumin 4.0317263510
MESH:D008591 Meningomyelocele Tretinoin 4.2916940565
MESH:D008654 Mesothelioma Asbestos, Crocidolite 3.1316166281 16966607 18303189
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.6616801185
MESH:D008679 Metaplasia Ozone 4.9810496685
MESH:D018200 Mixed Tumor, Mullerian Raloxifene 5.4315863610
MESH:D009101 Multiple Myeloma alachlor 11.8214769641
MESH:D009101 Multiple Myeloma Curcumin 11.8219372569
MESH:D009101 Multiple Myeloma Raloxifene 11.8216497877
MESH:D009134 Muscular Atrophy, Spinal Curcumin 4.7917962980
MESH:D009135 Muscular Diseases pirinixic acid 3.3816239165
MESH:D009190 Myelodysplastic Syndromes Tretinoin 3.0117596541
MESH:D009203 Myocardial Infarction Genistein 5.5017141266
MESH:D009203 Myocardial Infarction pirinixic acid 5.5019151258
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 2.9112213967
MESH:D015428 Myocardial Reperfusion Injury Genistein 8.0517141266
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 8.0516411023
MESH:D009232 Myxoma Raloxifene 5.4316343187
MESH:D009361 Neoplasm Invasiveness Curcumin 4.2418495463
MESH:D009362 Neoplasm Metastasis Tamoxifen 2.4919393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.4719410462
MESH:D009369 Neoplasms 4-phenylbutyric acid 8.0219116145
MESH:D009369 Neoplasms pirinixic acid 8.0217405874
MESH:D009369 Neoplasms Tretinoin 8.0216946489 16594593
MESH:D009376 Neoplasms, Hormone-Dependent Curcumin 10.4112497104
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 10.4119189210 19196722 19200415
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.3117954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.1719348381 18481113
MESH:D009421 Nervous System Malformations bisphenol A 22.4016427766 11399458
MESH:D009421 Nervous System Malformations Genistein 22.4016427766
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 22.4014600291
MESH:D009421 Nervous System Malformations Tretinoin 22.409125849
MESH:D009423 Nervous System Neoplasms Curcumin 5.5018462866
MESH:D009436 Neural Tube Defects Tretinoin 2.979142499
MESH:D009669 Nose Neoplasms alachlor 4.6916178123 16698726 14563481 11127290 15580706
MESH:D009765 Obesity Curcumin 7.2419297423
MESH:D009765 Obesity Dietary Fats 7.2418674790 11836018 19632207 16723640 21332399 18457598 17217161 20132043 20518802
MESH:D009765 Obesity pirinixic acid 7.2420558911
MESH:D010024 Osteoporosis Alendronate 16.3417882678
MESH:D010024 Osteoporosis Curcumin 16.3418719352
MESH:D010024 Osteoporosis Genistein 16.3419401787
MESH:D010024 Osteoporosis Raloxifene 16.3417882678 15775268 19059307
MESH:D015663 Osteoporosis, Postmenopausal Genistein 9.7316169203
MESH:D015663 Osteoporosis, Postmenopausal Raloxifene 9.7317893378 17823083 15758505 15579764
MESH:D010049 Ovarian Diseases bisphenol A 4.8611985600
MESH:D010051 Ovarian Neoplasms Curcumin 7.7418462866 19020741
MESH:D010051 Ovarian Neoplasms Genistein 7.7419005980
MESH:D010051 Ovarian Neoplasms Tretinoin 7.7416936753
MESH:D010146 Pain Tretinoin 2.8016870215
MESH:D010190 Pancreatic Neoplasms Curcumin 5.2819196508 17440100 19401701
MESH:D010190 Pancreatic Neoplasms Tretinoin 5.2815976015
MESH:D010195 Pancreatitis Trinitrobenzenesulfonic Acid 4.0817698068
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.5611578682
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.1212520081
MESH:D010538 Peritonitis Ozone 4.0016369182
MESH:D010995 Pleural Diseases Asbestos, Crocidolite 4.7610923243
MESH:D011014 Pneumonia Ozone 4.2618929643 18007984 18381685
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.4318163543
MESH:D011230 Precancerous Conditions Cyclosporine 3.1112371664
MESH:D011297 Prenatal Exposure Delayed Effects bisphenol A 9.0710548101
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 9.0711222880 11896295 11399792 11118676
MESH:D019048 Prostatic Intraepithelial Neoplasia bisphenol A 4.0920887781
MESH:D011471 Prostatic Neoplasms bisphenol A 1.8916740699
MESH:D011471 Prostatic Neoplasms Curcumin 1.8915129424 18226269 10851300 18156803 11398177 18769126 12497104
MESH:D011471 Prostatic Neoplasms Genistein 1.8915378649 15256057 16925846
MESH:D011471 Prostatic Neoplasms Raloxifene 1.8916536755 15731164 16220300
MESH:D011471 Prostatic Neoplasms Tamoxifen 1.8915067354
MESH:D011507 Proteinuria Tretinoin 3.4816636307
MESH:D011537 Pruritus Ethinyl Estradiol 3.1815861022 16919318
MESH:D011565 Psoriasis Cyclosporine 2.1816882103
MESH:D011625 Pterygium Tretinoin 4.6616723453
MESH:D011629 Puberty, Precocious bisphenol A 4.6510548101
MESH:D011656 Pulmonary Emphysema Curcumin 4.4119168576
MESH:D011658 Pulmonary Fibrosis Asbestos, Crocidolite 2.9817365031 15814490 17322281 17975199
MESH:D011693 Purpura Raloxifene 5.4315770314
MESH:D015427 Reperfusion Injury pirinixic acid 2.3219058328
MESH:D012128 Respiratory Distress Syndrome, Adult Curcumin 3.9018379247 10666014
MESH:D012135 Respiratory Sounds alachlor 4.8211874814
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.7118990726
MESH:D012208 Rhabdomyosarcoma Tretinoin 3.9816283617 16116481
MESH:D012509 Sarcoma Curcumin 4.0018462866
MESH:D018805 Sepsis Curcumin 3.9718389075
MESH:D012878 Skin Neoplasms tert-Butylhydroperoxide 9.078532709
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 9.0716192470
MESH:D012878 Skin Neoplasms Tretinoin 9.0716467112
MESH:D013088 Spermatocele Ethinyl Estradiol 11.1316709447
MESH:D013088 Spermatocele Tamoxifen 11.1316709447
MESH:D013119 Spinal Cord Injuries Tamoxifen 3.9119457130
MESH:D013274 Stomach Neoplasms Tretinoin 1.7917261132
MESH:D013276 Stomach Ulcer Curcumin 3.3819188055 16631530
MESH:D020521 Stroke Raloxifene 3.7216837676
MESH:D019966 Substance-Related Disorders bisphenol A 3.8516045194 16684133
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.5011994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.0415669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.7712697716
MESH:D013964 Thyroid Neoplasms alachlor 7.318812207
MESH:D013964 Thyroid Neoplasms Tretinoin 7.3117045167 16026305
MESH:D013978 Tibial Fractures Raloxifene 5.0819048282
MESH:D014062 Tongue Neoplasms Tretinoin 3.6716051514
MESH:D014376 Tuberculosis Tretinoin 3.1516040207
MESH:D001749 Urinary Bladder Neoplasms Curcumin 8.1418593936
MESH:D001749 Urinary Bladder Neoplasms Raloxifene 8.1417572228
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 8.1416712894 17572228 8653321
MESH:D014565 Urogenital Neoplasms Curcumin 5.1318462866
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 3.5616129372
MESH:D014591 Uterine Diseases bisphenol A 4.8814652134
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.1714692618
MESH:D014604 Uveal Neoplasms Tretinoin 4.4816752155
MESH:D014605 Uveitis Cyclosporine 3.851336536
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.4712125929
MESH:D054556 Venous Thromboembolism Raloxifene 5.0816837676
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.4214671159 15869587
MESH:D014820 Vitiligo Tretinoin 3.9316761959
MESH:D014846 Vulvar Neoplasms Raloxifene 5.4316343187
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.1215886252
MESH:D015430 Weight Gain Dietary Fats 3.6216723640
MESH:D009396 Wilms Tumor Tretinoin 3.8516287080
MESH:D014985 Xerophthalmia Cyclosporine 4.3117120751
Pathway ID Pathway Name
KEGG:05146 Amoebiasis
REACT:18266 Axon guidance
KEGG:04512 ECM-receptor interaction
KEGG:04510 Focal adhesion
KEGG:04974 Protein digestion and absorption
REACT:16888 Signaling by PDGF
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Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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